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Plasmodium Vivax 

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  1. Open Access 01-12-2024 | Plasmodium Vivax | OriginalPaper

    Epidemiology of Plasmodium vivax in Duffy negatives and Duffy positives from community and health centre collections in Ethiopia

    In spite of significant progress towards malaria control in the past two decades, malaria remains a major cause of mortality and morbidity in Africa [ 1 ]. According to the World Health Organization, Plasmodium vivax and Plasmodium falciparum …

  2. Open Access 01-12-2024 | Plasmodium Vivax | OriginalPaper

    Genetic differentiation of Plasmodium vivax duffy binding protein in Ethiopia and comparison with other geographical isolates

    In 2022, there were an estimated of 6.9 million cases of Plasmodium vivax globally [ 1 ]. Plasmodium vivax malaria is recognized as a cause of severe morbidity and mortality, with a significant negative impact on health in endemic countries [ 2 – 4 …]. The unique biological features of

  3. Open Access 01-12-2024 | Plasmodium Vivax | OriginalPaper

    Radical cure for Plasmodium vivax malaria after G6PD qualitative testing in four provinces in Cambodia, results from Phase I implementation

    Individuals infected with Plasmodium vivax may suffer from relapses caused by dormant liver parasites (hypnozoites). Globally between 60 to 96% of P. vivax infections are due to hypnozoite reactivation [ 1 – 3 ]. These relapses can occur within …

  4. Open Access 01-12-2024 | OriginalPaper

    Genomic insights into Plasmodium vivax population structure and diversity in central Africa

    The widespread fixation of the Duffy-negative phenotype in the human population in sub-Saharan Africa, which provides protection from Plasmodium vivax , is one of the most remarkable cases of natural selection documented in human populations [ 1 – …

  5. Open Access 01-12-2024 | Plasmodium Vivax | OriginalPaper

    In-vitro susceptibility and ex-vivo evaluation of macrocyclic lactone endectocides sub-lethal concentrations against Plasmodium vivax oocyst development in Anopheles arabiensis

    Malaria is a life-threatening disease, especially in children, with a high prevalence in sub-Saharan Africa. Globally, an estimated 247 million malaria cases and 619,000 malaria deaths were reported in 2021, of which more than 95% of the cases and …

  6. Open Access 01-12-2024 | Plasmodium Vivax | OriginalPaper

    Presence of Plasmodium vivax in Anopheles gambiae and absence in other malaria vectors in Cove-Zagnanando-Ouinhi health zone in southern Benin, West Africa

    Malaria is a disease caused by a pathogen transmitted to humans by female Anopheles mosquitoes. Despite the goal set by the World Health Organization (WHO) to reduce the global burden of malaria to 90% by 2030 [ 1 ], malaria-related morbidity and …

  7. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Human monoclonal antibodies inhibit invasion of transgenic Plasmodium knowlesi expressing Plasmodium vivax Duffy binding protein

    The estimated annual global burden of Plasmodium vivax malaria is 14.3 million (13.7 to 15.0 million) cases [ 1 ]. However, this approximation of P. vivax clinical cases grossly underestimates P. vivax asymptomatic or latent infections in the …

  8. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Imported and indigenous Plasmodium Vivax and Plasmodium Falciparum malaria in the Hubei Province of China, 2005–2019

    Malaria is one of the most serious public health problems worldwide. In 2021, 84 malaria-endemic countries reported 247 million malaria cases and 619,000 malaria-attributed deaths. Most malaria cases (95%) occurred in the African region, followed …

  9. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs

    One of the key obstacles to malaria elimination is largely attributed to Plasmodium vivax’s ability to form resilient hypnozoites in the host liver that cause relapsing infections. As a result, interruption of P. vivax transmission is difficult.

  10. Open Access 01-12-2023 | Plasmodium Knowlesi | Erratum

    Correction: Droplet digital polymerase chain reaction (ddPCR) for the detection of Plasmodium knowlesi and Plasmodium vivax

  11. Open Access 01-12-2023 | Plasmodium Falciparum | OriginalPaper

    Changing epidemiology of Plasmodium vivax malaria in Nouakchott, Mauritania: a six-year (2015–2020) prospective study

    Despite considerable multisectoral, international efforts to control and eliminate malaria since the end of the Second World War, malaria is still one of the most devastating infectious diseases worldwide, particularly in the tropics. According to …

  12. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Genetic diversity of merozoite surface protein-5 (MSP-5) of Plasmodium vivax isolates from Malaria patients in Iran

    Malaria has not yet been eradicated in Iran, and Plasmodium vivax (P. vivax) is the main cause of malaria in the country. This study aimed to investigate and analyze the amount of genetic diversity of Plasmodium vivax merozoite surface protein-5 …

  13. Open Access 01-12-2023 | Malaria | OriginalPaper

    A fatal respiratory complication of malaria caused by Plasmodium vivax

    Malaria is an endemic disease in Brazil, and Plasmodium vivax is the most prevalent causing species, implicated in over 80% locally diagnosed cases. Plasmodium vivax infection is usually associated with benign presentations of malaria. However …

  14. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Molecular surveillance of chloroquine resistance in Plasmodium vivax isolates from malaria cases in Yunnan Province of China using pvcrt-o gene polymorphisms

    Chloroquine (CQ), an anti-malarial drug that kills intraerythrocytic Plasmodium parasites, has long been the preferred treatment for controlling and eliminating the clinical symptoms of malaria, since it was first synthesized in 1934 [ 1 , 2 ], and …

  15. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Treatment of uncomplicated Plasmodium vivax with chloroquine plus radical cure with primaquine without G6PDd testing is safe in Arba Minch, Ethiopia: assessment of clinical and parasitological response

    Ethiopia achieved the Global Technical Strategy for Malaria (GTS) target; case incidence decreased by more than 40% in 2020 compared with the 2015 baseline [ 1 ]. Yet, malaria continued to be one of the public health challenges with estimated 55 …

  16. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates

    The control of malaria still continues to pose a problem in endemic countries, especially due to emergence and spread of drug resistant Plasmodium parasites across the globe [ 1 ]. Plasmodium falciparum and Plasmodium vivax are responsible for the …

  17. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Development of a Plasmodium vivax biobank for functional ex vivo assays

    Plasmodium vivax is the most geographically widespread malaria parasite species and is responsible for the second highest burden of malaria globally. While the total incidence of P. vivax has decreased globally from 20.5 million cases in 2000 to …

  18. Open Access 01-12-2023 | Plasmodium Ovale | OriginalPaper

    Analysis of the relapse of imported Plasmodium vivax and Plasmodium ovale in five provinces of China

    Global malaria cases experienced a significant increase of 14 million in 2020 compared to 2019, with a corresponding increase of 69,000 deaths [ 1 ]. The global fight against malaria is facing severe challenges. Notably, global malaria control …

  19. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Effect of adherence to primaquine on the risk of Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

    Early diagnosis and effective treatment of malaria are critical to achieving the ambitious goals of reducing malaria case incidence and mortality rates by at least 90% and eliminating malaria in at least 35 countries by 2030 [ 1 , 2 ].

  20. Open Access 01-12-2023 | Plasmodium Vivax | OriginalPaper

    Genetic diversity and natural selection of Plasmodium vivax reticulocyte invasion genes in Ecuador

    Malaria has been a major public health problem worldwide. In 2021, an estimated 247 million cases of malaria occurred, and 619,000 deaths were reported globally. In the Americas, malaria is primarily distributed in the Southern hemisphere and …

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