Plasmodium ovale malaria is usually considered a tropical infectious disease associated with low morbidity and mortality. However, severe disease and death have previously been reported [ 1 ]. A case of severe P. ovale malaria with a triangle …

Globally and nationally, malaria is an important tropical disease caused by Plasmodium species. Five Plasmodium parasite species are known to cause malaria in humans. They are P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi. Of …

Global malaria cases experienced a significant increase of 14 million in 2020 compared to 2019, with a corresponding increase of 69,000 deaths [ 1 ]. The global fight against malaria is facing severe challenges. Notably, global malaria control …

During the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main data sources: from detailed descriptive morphology, from observational histories of …

Eradication of malaria is still among the major priorities in the malaria research agenda as the disease continues to kill thousands of peoples worldwide [ 1 ]. In 2017, the World Health Organization (WHO) estimated 219 million cases of malaria and …

Malaria remains a major global public health concern. In 2018, studies have estimated 228 million malaria cases, leading to 405,000 deaths worldwide [ 1 ]. Most malaria cases (93%) and deaths (94%) were in the World Health Organization (WHO) …

The increase of imported ovale malaria cases are a cause of concern in non-endemic and malaria-free countries. For instance, Canada diagnosed 49 cases from 2006 to 2015 [ 1 ]; Spain reported 35 cases from 2005 to 2011 [ 2 , 3 ]; the USA diagnosed …

Malaria is one of the major global public health threats and causes substantial morbidity, mortality, and human suffering. In 2017, an estimated 219 million malaria cases occurred worldwide, with 435,000 deaths reported [ 1 ]. In humans, malaria is …

Plasmodium ovale curtisi and P. ovale wallikeri are two non-falciparum malaria (NFM) disease-causing sympatric species endemic to areas in Southeast Asia and particularly in Central and West Africa [ 1 , 2 ]. A recent systematic review of P. ovale …

Malaria remains a global health problem with more than 212 million new cases in 2016 and 429,000 annual deaths worldwide, mostly driven by Plasmodium falciparum and Plasmodium vivax , to which most of the research resources are devoted [ 1 ].

Approximately 2.5 billion people, or one-third of the world’s estimated 2018 population live in regions of stable or unstable malaria transmission, and are at risk for infection [ 1 , 2 ]. In sub-Saharan Africa, Plasmodium falciparum has been the …

Human Plasmodium ovale spp. malaria is caused by two different sympatric Plasmodium species, namely P. ovale curtisi , which was considered the “classic” human pathogen, and P. ovale wallikeri , which has been described as a genetically …

Plasmodium ovale malaria has been neglected largely from research in the past decades with the primary focus being laid on falciparum and to a lesser extent vivax malaria. Even though evidence is scarce, P. ovale is considered a relapsing …

Plasmodium ovale spp . and P. malariae malaria are less common than P. falciparum and P. vivax and cause a milder clinical syndrome than P. falciparum . As a result, much less is known about them. Although mostly found in Africa, they are both …

Plasmodium ovale is one species of malaria parasites that is pathogenic to humans [ 1 ]. Prevalent in West and East Africa and the Asia–Pacific [ 1 ], P. ovale infections can be challenging to diagnose in part due to the typical presentation of …

Although Plasmodium ovale is considered the cause of only mild malaria, some reports indicate the potential evolution to severe disease and even death [ 1 ]. A case of severe ovale malaria with acute respiratory distress syndrome (ARDS) …

Mixed-species malaria infections have received sporadic attention [ 1 ], and the trend toward malaria control in some endemic areas should reduce the occurrence of concurrent infection with more than one species of Plasmodium . However, diagnostic …

Plasmodium ovale was first described in 1922 [ 1 ], as the fourth malaria parasite of humans [ 2 , 3 ]. Generally, a P. ovale infection is of low parasitaemia, and the morphology of the parasite is similar to Plasmodium vivax . Also, it frequently …

Malaria incidence has recently been declining globally, although in many African countries it is still one of the top health problems. The efforts to control and eradicate malaria will still need a strong diagnostic capacity, which allows any …