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Non-Tuberculous Mycobacteria 

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  1. Open Access 01-12-2024 | Non-Tuberculous Mycobacteria | OriginalPaper

    The additional value of 18F-FDG PET/CT imaging in guiding the treatment strategy of non-tuberculous mycobacterial patients

    Non-tuberculous mycobacteria (NTM) are Mycobacterium ( M. ) species other than M. leprae and M. tuberculous . NTM are prevalent in the environment, such as soil, dust, plants, water sources, foods, and animals, and are more likely to infect …

  2. 12-12-2023 | Antibiotic | OriginalPaper

    Comparison of treatment modalities for non-tuberculous mycobacterial cervicofacial lymphadenitis in children

    The distinct clinical presentation of cervicofacial lymphadenitis caused by tuberculous pathogens was already well known in the Middle Ages under the name of Scrofula. Historically, the causative pathogen was almost always tuberculous in origin …

  3. Open Access 01-01-2024 | Non-Tuberculous Mycobacteria | OriginalPaper

    Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis

    Infections are among the most frequent complications occurring in patients receiving hematopoietic stem cell transplant (HSCT) [ 1 ]. As diagnostic techniques advanced, specific cultures are now able to identify a wide spectrum of pathogens causing …

  4. 09-12-2023 | Non-Tuberculous Mycobacteria | Online First

    The successful treatment of microscopic polyangiitis associated with non-tuberculous mycobacterial-pulmonary disease

    While the incidence and prevalence of non-tuberculous mycobacterial-pulmonary disease (NTM-PD) are increasing and microscopic polyangiitis (MPA) is common in East Asian countries, case reports of MPA associated with NTM-PD are limited. A …

  5. Open Access 01-12-2023 | Non-Tuberculous Mycobacteria | ReviewPaper

    Treatable traits and challenges in the clinical management of non-tuberculous mycobacteria lung disease in people with cystic fibrosis

    Cystic fibrosis (CF) is a lethal inherited disease characterized by multiorgan manifestations with morbidity and mortality primarily arising from CF-related lung involvement [ 1 – 3 ]. Systemic manifestations result from the impairment of the …

  6. Open Access 01-12-2023 | Bronchiectasis | OriginalPaper

    A case-control study on the risk factors associated with the occurrence of non-tuberculous mycobacteria pulmonary disease in bronchiectasis patients

    Bronchiectasis(BCS) is a chronic respiratory disease characterised by a clinical syndrome of cough, sputum production, and bronchial infection, Radiologically,it is identified by abnormal and permanent dilatation of the bronchi [ 1 ]. The …

  7. Open Access 01-12-2023 | Non-Tuberculous Mycobacteria | OriginalPaper

    Species identification and drug susceptibility testing of non-tuberculous mycobacteria by Line Probe Assay in Lambaréné, Gabon—a cross-sectional study

    Non-tuberculous mycobacteria (NTM) are mycobacteria other than M. tuberculosis and M. leprae . They are environmental pathogens predominantly found in water, soil, dust and animal sources [ 1 ]. In the past, NTM infections did not attract much …

  8. Open Access 01-12-2023 | Moxifloxacin | OriginalPaper

    Disseminated non-tuberculous mycobacterial infection caused by Mycobacterium obuense in an immunocompromised patient: a case report

    The prevalence of non-tuberculous mycobacterial (NTM) disease is increasing worldwide and is becoming a serious public health concern [ 1 , 2 ]. Although more than 180 species have been discovered, only a few have been reported to be pathogenic [ 3 …]. The most common causative organisms of human infections are the slowly growing mycobacteria

  9. Open Access 01-12-2023 | Non-Tuberculous Mycobacteria | OriginalPaper

    Non-tuberculous mycobacteria lung disease due to Mycobacterium chimaera in a 67-year-old man treated with immune checkpoint inhibitors for lung adenocarcinoma: infection due to dysregulated immunity?

    Immune checkpoint inhibitors (ICIs) are drugs growingly employed in cancer immunotherapy which have significantly improved the prognosis of several tumours. ICIs act by restoring the “exhausted” immune system and increasing the number of T cells …

  10. 10-01-2023 | Immunodeficiency | OriginalPaper

    Distinct Lymphocyte Immunophenotyping and Quantitative Anti-Interferon Gamma Autoantibodies in Taiwanese HIV-Negative Patients with Non-Tuberculous Mycobacterial Infections

    Patients with inhibitory and neutralizing autoantibodies against IFN-γ (AutoAbs-IFN-γ), as an adult-onset immunodeficiency [ 1 ] or anti-cytokine autoantibody syndrome [ 2 ], present with recurrent and various refractory non-tuberculous

  11. 01-12-2020 | Non-Tuberculous Mycobacteria | Original Research

    Longitudinal changes in health-related quality of life according to clinical course among patients with non-tuberculous mycobacterial pulmonary disease: a prospective cohort study

    The burden of non-tuberculous mycobacterial pulmonary disease (NTM-PD) has been increasing globally. An increased incidence of NTM-PD has been reported in East Asia [ 1 , 2 ], the United States [ 3 ], and Europe [ 4 ]. This phenomenon has also been …

  12. 01-02-2020 | Non-Tuberculous Mycobacteria | OriginalPaper

    Serum Anti-interferon-γ Autoantibody Titer as a Potential Biomarker of Disseminated Non-tuberculous Mycobacterial Infection

    Interferon-γ-neutralizing autoantibodies (IFNγ-Ab) have been detected in more than 80% of disseminated non-tuberculous mycobacterial (NTM) infection cases without an apparent pathological background leading to immunodeficiency [ 1 – 3 ]. The …

  13. Open Access 01-08-2022 | Non-Tuberculous Mycobacteria | OriginalPaper

    Diagnostic performance of metagenomic next-generation sequencing in non-tuberculous mycobacterial pulmonary disease when applied to clinical practice

    Non-tuberculous mycobacteria disease is caused by infection with nontuberculous mycobacteria (NTM) pathogens and is accompanied by pathological changes of related tissues and organs [ 1 – 3 ], among which pulmonary infection is the most common [ 4 …

  14. 05-12-2022 | Bronchiectasis | OriginalPaper

    Necroptosis-related subtypes are associated with bronchiectasis in pulmonary non-tuberculous mycobacteria-infected patients: a perspective based on transcriptomic analysis

    The aim of this study was to explore the potential mechanisms responsible for the different manifestations of bronchiectasis in patients with pulmonary non-tuberculous mycobacteria (pNTM) infection. We found that the necroptosis level increased …

  15. Open Access 01-12-2021 | Non-Tuberculous Mycobacteria | OriginalPaper

    Non-tuberculous mycobacterial pulmonary diseases in France: an 8 years nationwide study

    More than 190 species and subspecies of non-tuberculous mycobacteria (NTM) have been described. Among these, some like Mycobacterium avium complex (MAC), may cause pulmonary disease (NTM-PD) with increasing frequency in non-acquired …

  16. Open Access 01-12-2021 | Hemoptysis | OriginalPaper

    Factors affecting in-hospital mortality of non-tuberculous mycobacterial pulmonary disease

    Non-tuberculous mycobacterial pulmonary disease (NTM-PD) usually develops in middle-aged and older individuals, and is generally intractable and slowly progressive. The incidence and prevalence of NTM-PD are reportedly increasing in many parts of …

  17. Open Access 01-12-2021 | Tuberculosis | OriginalPaper

    Isolation of non-tuberculous mycobacteria among tuberculosis patients, a study from a tertiary care hospital in Lahore, Pakistan

    Non-tuberculous mycobacteria (NTM) are ubiquitous environmental acid-fast bacilli (AFB). Although NTM are not obligate pathogens, they share with M. tuberculosis complex (MBTC) the features of hardiness, hydrophobicity, aerosolization, and …

  18. 01-09-2021 | Cefoxitin | ReviewPaper

    Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Drug Treatment of Non-Tuberculous Mycobacteria in Cystic Fibrosis

    Non-tuberculous mycobacteria (NTM) are an emerging group of pulmonary infectious pathogens of increasing importance to the management of patients with cystic fibrosis (CF). NTM include slow-growing mycobacteria such as Mycobacterium avium complex …

  19. 01-11-2020 | Myelodysplastic Syndrome | Letter

    Non-Tuberculous Mycobacterial Infection in Hematopoietic Cell Transplant

  20. 01-08-2020 | Computed Tomography

    Radiologic Characteristics of Non-tuberculous Mycobacteria Infection in Patients with Bronchiectasis

    One of the most prominent features of bronchiectasis is chronic bacterial infection. The common bacterial infections in patients with bronchiectasis are Pseudomonas aeruginosa, Haemophilus influenzae , and non-tuberculous mycobacteria (NTM) [ 1 ].

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