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1801 search results for:

Dimethyl Fumarate 

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  1. Open Access 01-12-2024 | Dimethyl Fumarate | OriginalPaper

    Beneficial mechanisms of dimethyl fumarate in autoimmune uveitis: insights from single-cell RNA sequencing

    Autoimmune uveitis (AU) is an ocular autoimmune-inflammatory disease that imposes a substantial risk on visual acuity [ 1 ]. Patients suffering from AU encounter significant physical and economic burdens due to the recurrence and prolonged duration …

  2. 27-12-2023 | Dimethyl Fumarate | OriginalPaper

    Bariatric surgery and dimethyl fumarate-induced lymphopenia in patients with multiple sclerosis

    Dimethyl fumarate (DMF) is an oral disease-modifying therapy (DMT) for relapsing multiple sclerosis (R-MS). The phase III clinical trials demonstrated a favorable safety profile [ 1 , 2 ]. However, 5% of patients with MS (pwMS) in the phase 3 trial …

  3. Open Access 01-12-2024 | Dimethyl Fumarate | OriginalPaper

    Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease

    Alzheimer’s disease (AD) is the most common cause of dementia affecting elderly individuals. Patients with AD typically show a progressive decline in memory, language ability, and executive functions. Accumulation of amyloid-β and phosphorylated …

  4. 01-01-2024 | Rituximab | News

    Dimethyl-fumarate/Glatiramer-acetate/Rituximab

    Various toxicities
  5. 01-01-2024 | Human Alphaherpesvirus 3 | News

    Dimethyl-fumarate/interferon-beta-1a/natalizumab

    Cerebral varicella zoster virus vasculopathy and lack of efficacy
  6. 01-12-2023 | Dimethyl Fumarate | News

    Use of dimethyl fumarate for MS not linked to Fanconi syndrome

  7. 01-11-2023 | Pyoderma Gangrenosum | News

    Dimethyl fumarate/rituximab

    Lack of efficacy and pyoderma gangrenosum: 3 case reports
  8. 01-11-2023 | Fingolimod | News

    Dimethyl-fumarate/fingolimod

    Cryptococcal meningitis: case report
  9. 01-06-2023 | Quetiapine | News

    Dimethyl-fumarate/quetiapine

    Wells syndrome, nausea and abdominal pain: case report
  10. Open Access 01-12-2023 | Dimethyl Fumarate | OriginalPaper

    Repurposing dimethyl fumarate as an antiepileptogenic and disease-modifying treatment for drug-resistant epilepsy

    Over 65 million people worldwide suffer from epilepsy, one of the most prevalent and debilitating neurological diseases [ 1 ]. Epilepsy is responsible for a substantial share of the global disease burden [ 2 ], morbidity, and mortality [ 3 , 4 ].

  11. 01-04-2023 | Multiple Sclerosis | News

    Dimethyl-fumarate

    Lymphopenia and progressive multifocal leukoencephalopathy: 12 case reports
  12. 01-09-2023 | Dimethyl Fumarate | News

    Dimethyl-fumarate/methylprednisolone/tozinameran

    Herpes zoster: case report
  13. 01-08-2023 | Teriflunomide | OriginalPaper

    Dimethyl Fumarate or Teriflunomide for Relapsing–Remitting Multiple Sclerosis: A Meta-analysis of Post-marketing Studies

    In the absence of head-to-head comparison trials, we aimed to compare the effectiveness of two largely prescribed oral platform disease-modifying treatments for relapsing–remitting multiple sclerosis, namely, dimethyl fumarate (DMF) and …

  14. 01-11-2022 | Dimethyl Fumarate | News

    Dimethyl fumarate/ocrelizumab

    Cytomegalovirus meningitis, urosepsis and lymphopenia: case report
  15. 21-07-2023 | Dimethyl Fumarate | OriginalPaper

    Dimethyl fumarate inhibits ZNF217 and can be beneficial in a subset of estrogen receptor positive breast cancers

    Dimethyl fumarate (DMF) is an approved drug used in the treatment of multiple sclerosis and psoriasis [ 1 , 2 ]. DMF exhibits significant anti-cancer activities in breast cancer models by inhibiting inflammation, cancer stem-like properties and …

  16. 21-09-2023 | Multiple Sclerosis | News | Article

    Dimethyl fumarate associated with better RRMS outcomes than teriflunomide

    Treating relapsing–remitting multiple sclerosis patients with dimethyl fumarate versus teriflunomide is associated with more favorable clinical outcomes.

  17. 01-08-2023 | Lymphopenia | News

    Dimethyl-fumarate

    Prolonged lymphopenia: case report
  18. Open Access 24-06-2023 | Dimethyl Fumarate | OriginalPaper

    Real-World Safety and Effectiveness After 5 Years of Dimethyl Fumarate Treatment in Black and Hispanic Patients with Multiple Sclerosis in ESTEEM

    It has been reported that clinical course and disability outcomes associated with multiple sclerosis (MS) may vary by race and ethnicity [ 1 – 3 ]. However, MS has not been well studied in populations such as racial and ethnic minorities because …

  19. Open Access 01-12-2022 | Multiple Sclerosis | OriginalPaper

    Comparison of dimethyl fumarate and interferon outcomes in an MS cohort

    Multiple sclerosis (MS) is the most common demyelinating disease of the nervous system and a major cause of lifelong disability in the young adult population [ 1 ]. The first generation of disease-modifying therapies (DMT) for MS was approved in …

  20. Open Access 15-04-2023 | Multiple Sclerosis | OriginalPaper

    Efficacy of Dimethyl Fumarate in Young Adults with Relapsing-Remitting Multiple Sclerosis: Analysis of the DEFINE, CONFIRM, and ENDORSE Studies

    Multiple sclerosis (MS) is a chronic, demyelinating, inflammatory disease typically diagnosed at age 20–40 years [ 1 , 2 ]. In young adults, MS is a major cause of non-traumatic disability [ 2 ], placing a substantial burden on individuals and …

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