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Neurology and Therapy

Issue 3/2023

Content (21 Articles)

Open Access Migraine COMMENTARY

The Migraine Stigma Kaleidoscope View

Elena Gross, Elena Ruiz de la Torre, Paolo Martelletti

Open Access Alzheimer's Disease COMMENTARY

Clinical and Scientific Challenges to Effectiveness Studies Under Coverage with Evidence Development in Alzheimer’s Disease

Peter J. Morin, Quanwu Zhang, Weiming Xia, Donald Miller, Henry Querfurth, Amir Abbas Tahami Monfared

Open Access Alzheimer's Disease REVIEW

Dementia with Lewy Bodies Drug Therapies in Clinical Trials: Systematic Review up to 2022

Carla Abdelnour, Maria Camila Gonzalez, Lucy L. Gibson, Kathleen L. Poston, Clive G. Ballard, Jeffrey L. Cummings, Dag Aarsland

Open Access Multiple Sclerosis ORIGINAL RESEARCH

Genetically Determined Levels of mTOR-Dependent Circulating Proteins and Risk of Multiple Sclerosis

Yao-Chen Zhang, Ke-Yi Fan, Qi Wang, Jing-Xi Hu, Qian Wang, He-Yi Zhang, Shan Song, Rong Zhao, Jun Qiao, Sheng-Xiao Zhang

Open Access ORIGINAL RESEARCH

A Randomized, Double-Blind, Placebo-Controlled, Parallel Study Investigating the Efficacy of a Whole Coffee Cherry Extract and Phosphatidylserine Formulation on Cognitive Performance of Healthy Adults with Self-Perceived Memory Problems

Katarina M. Doma, Erin D. Lewis, Jane M. Barracato, Lauren R. Brink, Alejandra A. Gratson, Neeraj Pandey, David C. Crowley, Malkanthi Evans

Open Access Alzheimer's Disease ORIGINAL RESEARCH

Estimated Societal Value of Lecanemab in Patients with Early Alzheimer’s Disease Using Simulation Modeling

Amir Abbas Tahami Monfared, Weicheng Ye, Aditya Sardesai, Henri Folse, Ameya Chavan, Kang Kang, Quanwu Zhang

Open Access Pharmacokinetics ORIGINAL RESEARCH

Comparative Bioequivalence of Tablet and Capsule Formulations of Ulotaront and the Effect of Food on the Pharmacokinetics of the Tablet Form in Humans

Yu-Luan Chen, Hironobu Tsukada, Snezana Milanovic, Lei Shi, Yan Li, Yongcai Mao, Kenneth S. Koblan, Gerald R. Galluppi

Open Access Magnetic Resonance Imaging ORIGINAL RESEARCH

Long-Term Effectiveness and Safety of Natalizumab in African American and Hispanic/Latino Patients with Early Relapsing–Remitting Multiple Sclerosis: STRIVE Data Analysis

Jai Perumal, Roumen Balabanov, Laura Balcer, Steven Galetta, Zhaonan Sun, Hanyue Li, Danette Rutledge, Robin L. Avila, Robert J. Fox

Open Access Multiple Sclerosis ORIGINAL RESEARCH

Cost Per Relapse Avoided for Ozanimod Versus Other Selected Disease-Modifying Therapies for Relapsing–Remitting Multiple Sclerosis in the United States

Daniel Kantor, Timothy Pham, Oscar Patterson-Lomba, Elyse Swallow, Akanksha Dua, Komal Gupte-Singh

Open Access Care ORIGINAL RESEARCH

A Path to Improved Alzheimer’s Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer’s Disease from the CLARITY AD Trial

Amir Abbas Tahami Monfared, Weicheng Ye, Aditya Sardesai, Henri Folse, Ameya Chavan, Elena Aruffo, Quanwu Zhang

Open Access Multiple Sclerosis ORIGINAL RESEARCH

Efficacy of Dimethyl Fumarate in Young Adults with Relapsing-Remitting Multiple Sclerosis: Analysis of the DEFINE, CONFIRM, and ENDORSE Studies

Lilyana Amezcua, Yang Mao-Draayer, Wendy S. Vargas, Rebecca Farber, Sara Schaefer, Filipe Branco, Sarah M. England, Nicholas Belviso, James B. Lewin, Jason P. Mendoza, Sai L. Shankar

Open Access Alzheimer's Disease ORIGINAL RESEARCH

Understanding Barriers Along the Patient Journey in Alzheimer’s Disease Using Social Media Data

Amir Abbas Tahami Monfared, Yaakov Stern, Stephen Doogan, Michael Irizarry, Quanwu Zhang

Open Access Hematoma ORIGINAL RESEARCH

Optimizing The Timing of Stereotactic Minimally Invasive Drainage for Hypertensive Intracerebral Hemorrhage

Jingchen Li, Zhiyong Li, Lin Zhao, Yuanyu Wang, Jiankai Yang, Yan Feng, Xiaowei Zhang, Xiuwen Wu

Open Access Tuberous Sclerosis ORIGINAL RESEARCH

Effect of mTOR Inhibitors in Epilepsy Treatment in Children with Tuberous Sclerosis Complex Under 2 Years of Age

Dominika Śmiałek, Katarzyna Kotulska, Aleksandra Duda, Sergiusz Jóźwiak

Open Access Pharmacokinetics ORIGINAL RESEARCH

Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects

Beibei Liang, Jin Wang, Guanxuanzi Zhang, Rui Wang, Yun Cai

Open Access Spinal Muscular Atrophy ORIGINAL RESEARCH

The Alterations of Gut Microbiome and Lipid Metabolism in Patients with Spinal Muscular Atrophy

Yijie Feng, Yiqin Cui, Jianing Jin, Siyi Huang, Jia Wei, Mei Yao, Dongming Zhou, Shanshan Mao

Open Access Epilepsy Brief report

Frameless Robot-Assisted Asleep Centromedian Thalamic Nucleus Deep Brain Stimulation Surgery in Patients with Drug-Resistant Epilepsy: Technical Description and Short-Term Clinical Results

Changquan Wang, Jing Hong, Ziyu Mao, Wenze Chen, Bin Chen, Wenzhen Chen, Xiaolai Ye, Chencheng Zhang, Yong Lu, Qiangqiang Liu, Jiwen Xu

Open Access Alzheimer's Disease STUDY PROTOCOL

Design of a Non-Interventional Study to Assess Neurologists’ Perspectives and Pharmacological Treatment Decisions in Early Alzheimer's Disease

Gustavo Saposnik, Gonzalo Sánchez-Benavidez, Elena García-Arcelay, Emilio Franco-Macías, Catalina Bensi, Sebastián Carmelingo, Ricardo F. Allegri, David A. Pérez-Martínez, Jorge Maurino

Open Access Colchicine CASE REPORT

Familial Mediterranean Fever and Transverse Myelitis: A Causal Relation?

Ali Motahharynia, Ghazaal Alavi Tabatabaei, Reza Sarrafi, Saba Naghavi, Iman Adibi