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4074 search results for:

Apraxia 

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  1. 03-05-2024 | Intellectual Disability | Online First

    Expanding the clinical phenotype of SHANK2-related disorders: childhood apraxia of speech in a patient with a novel SHANK2 pathogenic variant

    Shankopathies are a spectrum of diseases associated with pathogenic genetic alterations in SHANK genes (SHANK1, SHANK2, SHANK3), which encode for structural proteins fundamental for synaptic formation and plasticity [ 1 ]. SHANK2 pathogenic …

  2. 07-04-2024 | Apraxia | Online First

    Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech

    Primary progressive apraxia of speech (PPAOS) is a motor speech disorder with insidious onset in which patients present with apraxia of speech (AOS) as the only initial symptom resulting from focal atrophy of the premotor cortex [ 1 ]. The main …

  3. 22-09-2023 | Blepharospasm | Letter

    Alternating unilateral blepharospasm with apraxia of eyelid opening in a patient with progressive supranuclear palsy

    Apraxia of lid opening (ALO) is a nonparalytic motor abnormality “characterized by difficulty initiating the act of lid elevation after lid closure” [ 2 ]. It often occurs together with blepharospasm but may also occur alone [ 2 ]. Most of the …

  4. 22-11-2023 | Apraxia | Online First

    Transcranial Alternating Current Stimulation in a Patient with Ataxia-Ocular Apraxia 2: a Case Report

    Ataxia-ocular apraxia 2 (AOA2) is a rare neurodegenerative autosomal recessive disorder with no effective treatment. In this study, we present the case of a patient diagnosed with AOA2, who experienced walking instability and uncoordinated …

  5. 03-06-2023 | Apraxia | ReviewPaper

    An Update on Apraxia of Speech

    Apraxia of speech (AOS) is a motor speech disorder that reflects disruptions in motor planning and programming. While AOS can occur as a developmental disorder (childhood apraxia of speech), and many of the same principles and descriptors apply to …

  6. Open Access 04-10-2023 | Aphasia | Online First

    Behavioral Treatment for Speech and Language in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech: A Systematic Review

    Primary progressive aphasia (PPA) and primary progressive apraxia of speech (PPAOS) are neurodegenerative syndromes characterized by progressive decline in language or speech. There is a growing number of studies investigating speech-language …

  7. Open Access 01-01-2022 | Apraxia | OriginalPaper

    Speech apraxia and oral apraxia: association or dissociation? A multivariate lesion–symptom mapping study in acute stroke patients

    The anatomical relationship between speech apraxia (SA) and oral apraxia (OA) is still unclear. To shed light on this matter we studied 137 patients with acute ischaemic left-hemisphere stroke and performed support vector regression-based …

  8. 04-05-2022 | Stroke | OriginalPaper

    Effect of Oral Apraxia on Dysphagia in Patients with Subacute Stroke

    Aim of this study was to investigate the effect of post-stroke oral apraxia on dysphagia in patients with subacute stroke. We retrospectively analyzed the clinical data of 130 supratentorial stroke patients from January 2015 to February 2021 who …

  9. 01-04-2022 | Apraxia | OriginalPaper

    Effects of anodal stimulation and motor practice on limb-kinetic apraxia in Parkinson’s disease

    Limb-kinetic apraxia, the loss of the ability to make precise, independent but coordinated finger and hand movements affects quality of life in patients with Parkinson’s disease. We aimed to examine the effects of anodal transcranial direct …

  10. Open Access 01-12-2023 | Coma | OriginalPaper

    The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued

    When David C. Cogan in a Jackson Memorial Lecture in 1952 described four children with a distinct disturbance of voluntary horizontal gaze characterized by the “inability to turn the eyes voluntarily in a direction for which there is full …

  11. 01-12-2021 | Frontotemporal Dementia | OriginalPaper

    Progressive apraxia of speech: delays to diagnosis and rates of alternative diagnoses

    Apraxia of speech (AOS) is a motor speech disorder characterized by impaired planning and/or programming of motor speech. Although the most common cause for acquired AOS is stroke, AOS occurs in neurodegenerative diseases as well. Consensus …

  12. Open Access 01-12-2023 | Apraxia | OriginalPaper

    Dose frequency randomized controlled trial for Dynamic Temporal and Tactile Cueing (DTTC) treatment for childhood apraxia of speech: protocol paper

    Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that affects the planning and programming of speech movements [ 1 , 2 ] and is estimated to occur in 1 per 1000 children [ 3 ]. Children with CAS typically have severe speech …

  13. 30-11-2021 | Stroke | OriginalPaper

    The Incidence of Aphasia, Cognitive Deficits, Apraxia, Dysarthria, and Dysphagia in Acute Post Stroke Persian Speaking Adults

    Stroke is a major cause of serious disabilities in adults. While communication deficits post stroke are prevalent and disabling, early detection of them is important during acute phase. There is limited data published on the incidence of …

  14. 01-07-2021 | Nystagmus | Letter

    Ataxia with oculomotor apraxia type 2 (AOA2): an eye movement study of two siblings

    Ataxia with oculomotor apraxia type 2 (AOA2) is an autosomal recessive disease due to mutations in the senataxin gene SETX (OMIM #606002), causing progressive cerebellar ataxia with peripheral neuropathy, cerebellar atrophy, oculomotor apraxia

  15. 01-12-2020 | Reading Disorder | Original Research

    Feature-driven classification reveals potential comorbid subtypes within childhood apraxia of speech

    Childhood Apraxia of Speech (CAS) is a speech sound disorder (SSD) with a range of severity, resulting in unintelligible speech that often persists into elementary school age and impacts language and literacy skills. Children with CAS demonstrate …

  16. Open Access 01-04-2020 | Apraxia | OriginalPaper

    Alien limb in the corticobasal syndrome: phenomenological characteristics and relationship to apraxia

    Alien limb refers to movements that seem purposeful but are independent of patients’ reported intentions. Alien limb often co-occurs with apraxia in the corticobasal syndrome, and anatomical and phenomenological comparisons have led to the …

  17. Open Access 01-12-2022 | Stroke | OriginalPaper

    The impact of apraxia and neglect on early rehabilitation outcome after stroke

    Given the increasing prevalence of stroke, its debilitating effects, and the following socioeconomic burden, improving the effects of rehabilitation on functional and cognitive outcomes remains a challenge. To this end, previous studies intended …

  18. 01-09-2020 | Apraxia | OriginalPaper

    Ioflupane 123I (DAT scan) SPECT identifies dopamine receptor dysfunction early in the disease course in progressive apraxia of speech

    Apraxia of speech (AOS) is a motor speech disorder in which the main problem is impaired planning and/or programming of speech [ 1 ]. Apraxia of speech may arise acutely after a left hemisphere stroke or may result from neurodegeneration, starting …

  19. 01-11-2019 | Apraxia | Letter

    Combination of olfactory aplasia and congenital ocular motor apraxia: a previously unreported association

  20. Open Access 01-12-2022 | Hydrocephalus | OriginalPaper

    Gait apraxia evaluation in normal pressure hydrocephalus using inertial sensors. Clinical correlates, ventriculoperitoneal shunt outcomes, and tap-test predictive capacity

    Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterised by normal cerebrospinal fluid (CSF) pressure associated with chronic ventricular dilation. Progressive gait impairments, urinary incontinence, and cognitive deficits …

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