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13-12-2022 | Stroke | Neuro-Images

Large vessel stroke and isolated thrombocytopenia as presenting features of thrombotic thrombocytopenic purpura

Authors: Marina Romozzi, Francesca Vitali, Giacomo Della Marca, Mauro Monforte, Aldobrando Broccolini

Published in: Neurological Sciences | Issue 4/2023

Excerpt

A 41-year-old right-handed woman was admitted with an acute onset of speech disturbance and confusion. On examination, she had impoverished speech, characterized by single words and perseveration, together with comprehension difficulties. Physical examination was normal, with no fever and purpuric lesions. Two months before, she had experienced a right quadrantanopia that lasted a week. On that occasion, the blood count showed isolated thrombocytopenia (70 × 10⁹/l). …

Sukumar S, Lämmle B, Cataland SR (2021) Thrombotic thrombocytopenic purpura: pathophysiology, diagnosis, and management. J Clin Med 10(3). https://doi.org/10.3390/jcm10030536

Sugarman R, Tufano AM, Liu JM (2018) Large vessel stroke as initial presentation of thrombotic thrombocytopenic purpura. BMJ Case Rep. https://doi.org/10.1136/bcr-2017-221857

Tomich C, Debruxelles S, Delmas Y, Sagnier S, Poli M, Olindo S, Renou P, Rouanet F, Sibon I (2018) Immune-thrombotic thrombocytopenic purpura is a rare cause of ischemic stroke in young adults: case reports and literature review. J Stroke Cerebrovasc Dis 27(11):3163–3171. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.07.017CrossRefPubMed

Title: Large vessel stroke and isolated thrombocytopenia as presenting features of thrombotic thrombocytopenic purpura
Authors: Marina Romozzi
Francesca Vitali
Giacomo Della Marca
Mauro Monforte
Aldobrando Broccolini
Publication date: 13-12-2022
Publisher: Springer International Publishing
Keywords: Stroke
Angiography
Thrombotic Thrombocytopenic Purpura
Cranial MRI
Thrombocytopenia
Aphasia
Published in: Neurological Sciences / Issue 4/2023
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-022-06549-z

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Large vessel stroke and isolated thrombocytopenia as presenting features of thrombotic thrombocytopenic purpura

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