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Diabetologia

Issue 1/2021

Content (25 Articles)

Editorial

The times they are a-changin’

Hindrik Mulder

Obesity Review

Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes

Kimberly M. Alonge, David A. D’Alessio, Michael W. Schwartz

Open Access Type 1 Diabetes Review

Presumption of guilt for T cells in type 1 diabetes: lead culprits or partners in crime depending on age of onset?

Alexia Carré, Sarah J. Richardson, Etienne Larger, Roberto Mallone

Probiotics Meta-analysis

The effect of probiotics, prebiotics or synbiotics on metabolic outcomes in individuals with diabetes: a systematic review and meta-analysis

Patricia M. Bock, Gabriela H. Telo, Rafaela Ramalho, Mariana Sbaraini, Gabriel Leivas, Andreza F. Martins, Beatriz D. Schaan

The effects of dapagliflozin, metformin or exercise on glycaemic variability in overweight or obese individuals with prediabetes (the PRE-D Trial): a multi-arm, randomised, controlled trial

Kristine Færch, Martin B. Blond, Lea Bruhn, Hanan Amadid, Dorte Vistisen, Kim K. B. Clemmensen, Camilla T. R. Vainø, Camilla Pedersen, Maria Tvermosegaard, Thomas F. Dejgaard, Kristian Karstoft, Mathias Ried-Larsen, Frederik Persson, Marit E. Jørgensen

Open Access Diabetic Retinopathy Article

Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT

Deborah M. Broadbent, Amu Wang, Christopher P. Cheyne, Marilyn James, James Lathe, Irene M. Stratton, John Roberts, Tracy Moitt, Jiten P. Vora, Mark Gabbay, Marta García-Fiñana, Simon P. Harding

Vitreous metabolomics profiling of proliferative diabetic retinopathy

Yohei Tomita, Gael Cagnone, Zhongjie Fu, Bertan Cakir, Yumi Kotoda, Masaki Asakage, Yoshihiro Wakabayashi, Ann Hellström, Jean-Sébastien Joyal, Saswata Talukdar, Lois E. H. Smith, Yoshihiko Usui

Obesity Article

Maternal blood glucose level and offspring glucose–insulin homeostasis: what is the role of offspring adiposity?

Ellen C. Francis, Dana Dabelea, Brandy M. Ringham, Katherine A. Sauder, Wei Perng

Open Access Type 2 Diabetes Article

Mortality in first- and second-generation immigrants to Sweden diagnosed with type 2 diabetes: a 10 year nationwide cohort study

Louise Bennet, Ruzan Udumyan, Carl Johan Östgren, Olov Rolandsson, Stefan P. O. Jansson, Per Wändell

Temporal trends in rates of infection-related hospitalisations in Hong Kong people with and without diabetes, 2001–2016: a retrospective study

Andrea O. Y. Luk, Hongjiang Wu, Eric S. H. Lau, Aimin Yang, Wing-Yee So, Elaine Chow, Alice P. S. Kong, David S. C. Hui, Ronald C. W. Ma, Juliana C. N. Chan

Open Access Type 1 Diabetes Article

Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes

Danièle Pacaud, Anita M. Nucci, David Cuthbertson, Dorothy J. Becker, Suvi M. Virtanen, Johnny Ludvigsson, Jorma Ilonen, Mikael Knip

Open Access Insulins Article

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

Marie-Sophie Nguyen-Tu, Aida Martinez-Sanchez, Isabelle Leclerc, Guy A. Rutter, Gabriela da Silva Xavier

Heparin Short Communication

Weekly injection of IL-2 using an injectable hydrogel reduces autoimmune diabetes incidence in NOD mice

Nadine Nagy, Gernot Kaber, Michael J. Kratochvil, Hedwich F. Kuipers, Shannon M. Ruppert, Koshika Yadava, Jason Yang, Sarah C. Heilshorn, S. Alice Long, Alberto Pugliese, Paul L. Bollyky

Obesity Article

Subcellular localisation and composition of intramuscular triacylglycerol influence insulin sensitivity in humans

Darcy Kahn, Leigh Perreault, Emily Macias, Simona Zarini, Sean A. Newsom, Allison Strauss, Anna Kerege, Kathleen Harrison, Janet Snell-Bergeon, Bryan C. Bergman

Obesity Article

Hypothalamic MC4R regulates glucose homeostasis through adrenaline-mediated control of glucose reabsorption via renal GLUT2 in mice

Leticia Maria de Souza Cordeiro, Arwa Elsheikh, Nagavardhini Devisetty, Donald A. Morgan, Steven N. Ebert, Kamal Rahmouni, Kavaljit H. Chhabra

Erythropoietin protects the inner blood–retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy

Hai Xie, Chaoyang Zhang, Dandan Liu, Qian Yang, Lei Tang, Tianqin Wang, Haibin Tian, Lixia Lu, Jing-Ying Xu, Furong Gao, Juan Wang, Caixia Jin, Weiye Li, Guoxu Xu, Guo-Tong Xu, Jingfa Zhang

Obesity Article

Senescence-associated β-galactosidase in subcutaneous adipose tissue associates with altered glycaemic status and truncal fat in severe obesity

Christine Rouault, Geneviève Marcelin, Solia Adriouch, Cindy Rose, Laurent Genser, Marc Ambrosini, Jean-Christophe Bichet, Yanyan Zhang, Florian Marquet, Judith Aron-Wisnewsky, Christine Poitou, Sébastien André, Geneviève Dérumeaux, Michèle Guerre-Millo, Karine Clément

Gestational Diabetes Research Letter

Effects of lifestyle intervention during pregnancy on postpartum diabetes among Chinese women with gestational diabetes

Ninghua Li, Jinnan Liu, Cuiping Zhang, Gongshu Liu, Junhong Leng, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Juliana C. N. Chan, Xilin Yang

Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study

Robert W. Koivula, Naeimeh Atabaki-Pasdar, Giuseppe N. Giordano, Tom White, Jerzy Adamski, Jimmy D. Bell, Joline Beulens, Søren Brage, Søren Brunak, Federico De Masi, Emmanouil T. Dermitzakis, Ian M. Forgie, Gary Frost, Torben Hansen, Tue H. Hansen, Andrew Hattersley, Tarja Kokkola, Azra Kurbasic, Markku Laakso, Andrea Mari, Timothy J. McDonald, Oluf Pedersen, Femke Rutters, Jochen M. Schwenk, Harriet J. A. Teare, E. Louise Thomas, Ana Vinuela, Anubha Mahajan, Mark I. McCarthy, Hartmut Ruetten, Mark Walker, Ewan Pearson, Imre Pavo, Paul W. Franks

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.