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Diabetologia

Issue 2/2021

Content (21 Articles)

Obesity Review

Brain JNK and metabolic disease

Rubén Nogueiras, Guadalupe Sabio

Open Access Diabetes Article

Impact of age at type 2 diabetes mellitus diagnosis on mortality and vascular complications: systematic review and meta-analyses

Natalie Nanayakkara, Andrea J. Curtis, Stephane Heritier, Adelle M. Gadowski, Meda E. Pavkov, Timothy Kenealy, David R. Owens, Rebecca L. Thomas, Soon Song, Jencia Wong, Juliana C.-N. Chan, Andrea O.-Y. Luk, Giuseppe Penno, Linong Ji, Viswanathan Mohan, Anandakumar Amutha, Pedro Romero-Aroca, Danijela Gasevic, Dianna J. Magliano, Helena J. Teede, John Chalmers, Sophia Zoungas

Open Access Prediabetes Article

The prevalence of cardiac autonomic neuropathy in prediabetes: a systematic review

Aikaterini Eleftheriadou, Scott Williams, Sarah Nevitt, Emily Brown, Rebecca Roylance, John P. H. Wilding, Daniel J. Cuthbertson, Uazman Alam

Do variations in insulin sensitivity and insulin secretion in pregnancy predict differences in obstetric and neonatal outcomes?

Lene R. Madsen, Kristen S. Gibbons, Ronald C. W. Ma, Wing Hung Tam, Patrick M. Catalano, David A. Sacks, Julia Lowe, H. David McIntyre

Open Access Epstein-Barr Virus Article

A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes

Bart Keymeulen, André van Maurik, Dave Inman, João Oliveira, Rene McLaughlin, Rachel M. Gittelman, Bart O. Roep, Pieter Gillard, Robert Hilbrands, Frans Gorus, Chantal Mathieu, Ursule Van de Velde, Nicolas Wisniacki, Antonella Napolitano

Circulating biomarkers of nitric oxide bioactivity and impaired muscle vasoreactivity to exercise in adults with uncomplicated type 1 diabetes

Elodie Lespagnol, Sémah Tagougui, Bernadette O. Fernandez, Farid Zerimech, Régis Matran, Patrice Maboudou, Serge Berthoin, Amandine Descat, Isabelle Kim, Mehdi Pawlak-Chaouch, Julien Boissière, Eric Boulanger, Martin Feelisch, Pierre Fontaine, Elsa Heyman

Open Access Polycystic Ovary Syndrome Article

Anti-Müllerian hormone levels and risk of type 2 diabetes in women

Renée M. G. Verdiesen, N. Charlotte Onland-Moret, Carla H. van Gils, Rebecca K. Stellato, Annemieke M. W. Spijkerman, H. Susan J. Picavet, Frank J. M. Broekmans, W. M. Monique Verschuren, Yvonne T. van der Schouw

Increased particle size of triacylglycerol-enriched remnant lipoproteins, but not their plasma concentration or lipid content, augments risk prediction of incident type 2 diabetes

Luiz Sérgio F. Carvalho, Isabela M. Benseñor, Ana C. C. Nogueira, Bruce B. Duncan, Maria I. Schmidt, Michael J. Blaha, Peter P. Toth, Steven R. Jones, Raul D. Santos, Paulo A. Lotufo, Andrei C. Sposito

Metformin Article

The interaction between metformin and physical activity on postprandial glucose and glucose kinetics: a randomised, clinical trial

Nanna S. Pilmark, Mark Lyngbæk, Laura Oberholzer, Ida Elkjær, Christina Petersen-Bønding, Katja Kofoed, Christoph Siebenmann, Katja Kellenberger, Gerrit van Hall, Julie Abildgaard, Helga Ellingsgaard, Carsten Lauridsen, Mathias Ried-Larsen, Bente K. Pedersen, Katrine B. Hansen, Kristian Karstoft

Open Access Insulins Article

Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men

Sindre Lee, Hanne L. Gulseth, Torgrim M. Langleite, Frode Norheim, Thomas Olsen, Helga Refsum, Jørgen Jensen, Kåre I. Birkeland, Christian A. Drevon

Open Access Insulins Article

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Alexandre Houzelle, Johanna A. Jörgensen, Gert Schaart, Sabine Daemen, Nynke van Polanen, Ciarán E. Fealy, Matthijs K. C. Hesselink, Patrick Schrauwen, Joris Hoeks

Effects of long-term vitamin D and n-3 fatty acid supplementation on inflammatory and cardiac biomarkers in patients with type 2 diabetes: secondary analyses from a randomised controlled trial

Christine P. Limonte, Leila R. Zelnick, John Ruzinski, Andrew N. Hoofnagle, Ravi Thadhani, Michal L. Melamed, I-Min Lee, Julie E. Buring, Howard D. Sesso, JoAnn E. Manson, Ian H. de Boer

Open Access Mood Disorders Article

Depression as a risk factor for dementia in older people with type 2 diabetes and the mediating effect of inflammation

Alistair L. Carr, Anniek J. Sluiman, Sheila M. Grecian, Rachel Forster, Stela McLachlan, Mark W. J. Strachan, Jackie F. Price

Open Access Type 2 Diabetes Article

Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes

Dan Ziegler, Alexander Strom, Klaus Straßburger, Birgit Knebel, Gidon J. Bönhof, Jörg Kotzka, Julia Szendroedi, Michael Roden

Diabetic Nephropathy Short Communication

Urinary podocyte-derived microparticles in youth with type 1 and type 2 diabetes

Katie M. Sullivan, James Scholey, Rahim Moineddin, Etienne Sochett, Brandy Wicklow, Yesmino Elia, Feng Xiao, Thalia Mederios, Pusha Sadi, Dylan Burger, Farid H. Mahmud, Alison B. Dart

Correction to: Urinary podocyte-derived microparticles in youth with type 1 and type 2 diabetes

Katie M. Sullivan, James Scholey, Rahim Moineddin, Etienne Sochett, Brandy Wicklow, Yesmino Elia, Fengxia Xiao, Thalia Medeiros, Pusha Sadi, Dylan Burger, Farid H. Mahmud, Alison B. Dart

Correction to: Effects of long-term vitamin D and n-3 fatty acid supplementation on inflammatory and cardiac biomarkers in patients with type 2 diabetes: secondary analyses from a randomised controlled trial

Christine P. Limonte, Leila R. Zelnick, John Ruzinski, Andrew N. Hoofnagle, Ravi Thadhani, Michal L. Melamed, I-Min Lee, Julie E. Buring, Howard D. Sesso, JoAnn E. Manson, Ian H. de Boer

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine