Issue 1/2013
Content (141 Articles)
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension
Nicole Pfarr, Christine Fischer, Nicola Ehlken, Tabea Becker-Grünig, Vanesa López-González, Matthias Gorenflo, Alfred Hager, Katrin Hinderhofer, Oliver Miera, Christian Nagel, Dietmar Schranz, Ekkehard Grünig
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling
Daniel J Angelini, Qingning Su, Kazuyo Yamaji-Kegan, Chunling Fan, John T Skinner, Andre Poloczek, Hazim El-Haddad, Chris Cheadle, Roger A Johns
Human leukocyte antigen-G expression in differentiated human airway epithelial cells: lack of modulation by Th2-associated cytokines
Steven R White, Dagan A Loisel, Randi Stern, Bharathi Laxman, Timothy Floreth, Bertha A Marroquin
Loss of alveolar membrane diffusing capacity and pulmonary capillary blood volume in pulmonary arterial hypertension
Samar Farha, Daniel Laskowski, Deepa George, Margaret M Park, WH Wilson Tang, Raed A Dweik, Serpil C Erzurum
The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
Isham Huizar, Anagha Malur, Janki Patel, Matthew McPeek, Larry Dobbs, Christopher Wingard, Barbara P Barna, Mary Jane Thomassen
IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice
Etsuko Kurimoto, Nobuaki Miyahara, Arihiko Kanehiro, Koichi Waseda, Akihiko Taniguchi, Genyo Ikeda, Hikari Koga, Hisakazu Nishimori, Yasushi Tanimoto, Mikio Kataoka, Yoichiro Iwakura, Erwin W Gelfand, Mitsune Tanimoto
Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses
Hikari Koga, Nobuaki Miyahara, Yasuko Fuchimoto, Genyo Ikeda, Koichi Waseda, Katsuichiro Ono, Yasushi Tanimoto, Mikio Kataoka, Erwin W Gelfand, Mitsune Tanimoto, Arihiko Kanehiro
Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study
Akkelies E Dijkstra, Dirkje S Postma, Nick ten Hacken, Judith M Vonk, Matthijs Oudkerk, Peter MA van Ooijen, Pieter Zanen, Firdaus A Mohamed Hoesein, Bram van Ginneken, Michael Schmidt, Harry JM Groen
Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD
Katherine J Baines, Alan C-Y Hsu, Melinda Tooze, Lakshitha P Gunawardhana, Peter G Gibson, Peter AB Wark
Diverging trends of chronic bronchitis and smoking habits between 1998 and 2010
Simone Accordini, Angelo Guido Corsico, Isa Cerveri, Leonardo Antonicelli, Francesco Attena, Roberto Bono, Lucio Casali, Marcello Ferrari, Alessandro Fois, Pierpaolo Marchetti, Pietro Pirina, Roberta Tassinari, Giuseppe Verlato, Roberto de Marco
Sputum mediator profiling and relationship to airway wall geometry imaging in severe asthma
Dhananjay Desai, Sumit Gupta, Salman Siddiqui, Amisha Singapuri, William Monteiro, James Entwisle, Sudha Visvanathan, Harsukh Parmar, Radhika Kajekar, Christopher E Brightling
Epigenetics of hypoxic pulmonary arterial hypertension following intrauterine growth retardation rat: epigenetics in PAH following IUGR
Xue-Feng Xu, Ying Lv, Wei-Zhong Gu, Li-Li Tang, Jia-Kai Wei, Li-Yan Zhang, Li-Zhong Du
Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study
Hortensia Moreno-Macías, Douglas W Dockery, Joel Schwartz, Diane R Gold, Nan M Laird, Juan J Sienra-Monge, Blanca E Del Río-Navarro, Matiana Ramírez-Aguilar, Albino Barraza-Villarreal, Huiling Li, Stephanie J London, Isabelle Romieu
Lung CD8+ T cells in COPD have increased expression of bacterial TLRs
Christine M Freeman, Fernando J Martinez, MeiLan K Han, George R Washko, Jr, Alexandra L McCubbrey, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Reviewer acknowledgement 2012
Jan Lötvall, Reynold A Panettieri Jr
Preliminary characterizations of a serum biomarker for sarcoidosis by comparative proteomic approach with tandem-mass spectrometry in ethnic Han Chinese patients
Yuan Zhang, Xianqiu Chen, Yang Hu, Shanshan Du, Li Shen, Yifan He, Yuxuan Zhang, Xia Zhang, Huiping Li, Rex C Yung
Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts
Anna-Karin Larsson-Callerfelt, Oskar Hallgren, Annika Andersson-Sjöland, Lena Thiman, Johan Björklund, Josefine Kron, Kristian Nihlberg, Leif Bjermer, Claes-Göran Löfdahl, Gunilla Westergren-Thorsson
Exercise training with negative pressure ventilation improves exercise capacity in patients with severe restrictive lung disease: a prospective controlled study
Shu-Chuan Ho, Horng-Chyuan Lin, Han-Pin Kuo, Li-Fei Chen, Te-Fang Sheng, Wen-Ching Jao, Chun-Hua Wang, Kang-Yun Lee
Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury
Stephan W Glasser, Albert P Senft, Melissa D Maxfield, Teah L Ruetschilling, John E Baatz, Kristen Page, Thomas R Korfhagen
Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms
Khondoker M Akram, Sohel Samad, Monica A Spiteri, Nicholas R Forsyth
Isolation and characterisation of human pulmonary microvascular endothelial cells from patients with severe emphysema
Laura S Mackay, Sara Dodd, Iain G Dougall, Wendy Tomlinson, James Lordan, Andrew J Fisher, Paul A Corris
Exploring factors influencing asthma control and asthma-specific health-related quality of life among children
Pranav K Gandhi, Kelly M Kenzik, Lindsay A Thompson, Darren A DeWalt, Dennis A Revicki, Elizabeth A Shenkman, I-Chan Huang
Apoptosis inhibitor of macrophage (AIM) expression in alveolar macrophages in COPD
Jun Kojima, Jun Araya, Hiromichi Hara, Saburo Ito, Naoki Takasaka, Kenji Kobayashi, Satoko Fujii, Chikako Tsurushige, Takanori Numata, Takeo Ishikawa, Kenichiro Shimizu, Makoto Kawaishi, Keisuke Saito, Noriki Kamiya, Jun Hirano, Makoto Odaka, Toshiaki Morikawa, Hiroshi Hano, Satoko Arai, Toru Miyazaki, Yumi Kaneko, Katsutoshi Nakayama, Kazuyoshi Kuwano
Infection, inflammation and exercise in cystic fibrosis
Pauline Barbera van de Weert-van Leeuwen, Hubertus Gerardus Maria Arets, Cornelis Korstiaan van der Ent, Jeffrey Matthijn Beekman
Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca2+/NFAT pathway
Xianhua Hou, Jian Chen, Yongjun Luo, Fuyu Liu, Gang Xu, Yuqi Gao
Comparative analysis of circulating dendritic cell subsets in patients with atopic diseases and sarcoidosis
Yumeko Hayashi, Yoshiki Ishii, Mitsumi Hata-Suzuki, Ryo Arai, Kazuyuki Chibana, Akihiro Takemasa, Takeshi Fukuda
Target renal damage: the microvascular associations of increased aortic stiffness in patients with COPD
Michelle John, Samia Hussain, Andrew Prayle, Rebecca Simms, John R Cockcroft, Charlotte E Bolton
Atopy is a risk factor for respiratory symptoms in COPD patients: results from the EUROSCOP study
Fatemeh Fattahi, Nick H T ten Hacken, Claes-Göran Löfdahl, Machteld N Hylkema, Wim Timens, Dirkje S Postma, Judith M Vonk
Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma
Keiko Kan-o, Yuko Matsunaga, Satoru Fukuyama, Atsushi Moriwaki, Hiroko Hirai-Kitajima, Takehiko Yokomizo, Kosuke Aritake, Yoshihiro Urade, Yoichi Nakanishi, Hiromasa Inoue, Koichiro Matsumoto
Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression
Jill C Todt, Christine M Freeman, Jeanette P Brown, Joanne Sonstein, Theresa M Ames, Alexandra L McCubbrey, Fernando J Martinez, Stephen W Chensue, James M Beck, Jeffrey L Curtis
Th17 cytokines induce pro-fibrotic cytokines release from human eosinophils
Saleh Al-Muhsen, Severine Letuve, Alejandro Vazquez-Tello, Mary Angeline Pureza, Hamdan Al-Jahdali, Ahmed S Bahammam, Qutayba Hamid, Rabih Halwani
Airway epithelial cells initiate the allergen response through transglutaminase 2 by inducing IL-33 expression and a subsequent Th2 response
Keunhee Oh, Myung Won Seo, Ga Young Lee, Ok-Jin Byoun, Hye-Ryun Kang, Sang-Heon Cho, Dong-Sup Lee
Bone morphogenetic proteins enhance an epithelial-mesenchymal transition in normal airway epithelial cells during restitution of a disrupted epithelium
Natasha McCormack, Emer L Molloy, Shirley O’Dea
Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs
Quanfu Mao, Sharon Chu, Sailaja Ghanta, James F Padbury, Monique E De Paepe
Three-year follow-up of Interleukin 6 and C-reactive protein in chronic obstructive pulmonary disease
Renata Ferrari, Suzana E Tanni, Laura MO Caram, Corina Corrêa, Camila R Corrêa, Irma Godoy
The Tiotropium Safety and Performance in Respimat® Trial (TIOSPIR®), a large scale, randomized, controlled, parallel-group trial-design and rationale
Robert A Wise, Antonio Anzueto, Peter Calverley, Ronald Dahl, Daniel Dusser, Gordon Pledger, Michael Koenen-Bergmann, Elizabeth Joseph, Daniel Cotton, Bernd Disse
Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1
Tiana V Curry-McCoy, Aida Venado, David M Guidot, Pratibha C Joshi
M2 macrophage polarisation is associated with alveolar formation during postnatal lung development
Christina V Jones, Timothy M Williams, Kenneth A Walker, Hayley Dickinson, Samy Sakkal, Bree A Rumballe, Melissa H Little, Graham Jenkin, Sharon D Ricardo
Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD
Craig P Hersh, George R Washko, Raúl San José Estépar, Sharon Lutz, Paul J Friedman, MeiLan K Han, John E Hokanson, Philip F Judy, David A Lynch, Barry J Make, Nathaniel Marchetti, John D Newell Jr, Frank C Sciurba, James D Crapo, Edwin K Silverman
Impact of exacerbations of cystic fibrosis on muscle strength
Chris Burtin, Hans Van Remoortel, Bart Vrijsen, Daniel Langer, Kristine Colpaert, Rik Gosselink, Marc Decramer, Lieven Dupont, Thierry Troosters
Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia
Huanxing Sun, Rayman Choo-Wing, Juan Fan, Lin Leng, Mansoor A Syed, Alissa A Hare, William L Jorgensen, Richard Bucala, Vineet Bhandari
Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies
Luka A Clarke, Lisete Sousa, Celeste Barreto, Margarida D Amaral
The current position of surgical lung biopsy in the diagnosis of idiopathic pulmonary fibrosis
Riitta Kaarteenaho
Current management of patients hospitalized with community-acquired pneumonia across Europe: outcomes from REACH
Francesco Blasi, Javier Garau, Jesús Medina, Marco Ávila, Kyle McBride, Helmut Ostermann
Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency
Stephanie Korn, Marisa Hübner, Matthias Jung, Maria Blettner, Roland Buhl
Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease
Donald P Tashkin, Gary T Ferguson
Role of exhaled nitric oxide as a predictor of atopy
Karina M Romero, Colin L Robinson, Lauren M Baumann, Robert H Gilman, Robert G Hamilton, Nadia N Hansel, William Checkley
Complications associated with endobronchial ultrasound-guided transbronchial needle aspiration: a nationwide survey by the Japan Society for Respiratory Endoscopy
Fumihiro Asano, Motoi Aoe, Yoshinobu Ohsaki, Yoshinori Okada, Shinji Sasada, Shigeki Sato, Eiichi Suzuki, Hiroshi Semba, Kazuya Fukuoka, Shozo Fujino, Kazumitsu Ohmori
Systemic inflammation, depression and obstructive pulmonary function: a population-based study
Yanxia Lu, Lei Feng, Liang Feng, Ma Shwe Nyunt, Keng Bee Yap, Tze Pin Ng
Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis
Yasunari Miyazaki, Koji Unoura, Tomoya Tateishi, Takumi Akashi, Tamiko Takemura, Makoto Tomita, Naohiko Inase, Yasuyuki Yoshizawa
Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury
Laura Amado-Rodríguez, Adrián González-López, Inés López-Alonso, Alina Aguirre, Aurora Astudillo, Estefanía Batalla-Solís, Jorge Blazquez-Prieto, Emilio García-Prieto, Guillermo M Albaiceta
The minimal important difference of the pulmonary functional status and dyspnea questionnaire in patients with severe chronic obstructive pulmonary disease
Eloisa MG Regueiro, Chris Burtin, Paul Baten, Daniel Langer, Hans Van Remoortel, Valéria A Pires Di Lorenzo, Dirceu Costa, Wim Janssens, Marc Decramer, Rik Gosselink, Thierry Troosters
Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust
Tara M Nordgren, Art J Heires, Todd A Wyatt, Jill A Poole, Tricia D LeVan, D Roselyn Cerutis, Debra J Romberger
Efficacy, safety and tolerability of GSK2190915, a 5-lipoxygenase activating protein inhibitor, in adults and adolescents with persistent asthma: a randomised dose-ranging study
Richard MA Follows, Neil G Snowise, Shu-Yen Ho, Claire L Ambery, Kevin Smart, Barbara A McQuade
Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
Yun-Yan Wan, Guang-Yan Tian, Hai-Sheng Guo, Yan-Meng Kang, Zhou-Hong Yao, Xi-Li Li, Qing-Hua Liu, Dian-Jie Lin
Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study
Kristin Blidberg, Lena Palmberg, Anna James, Bo Billing, Elisabeth Henriksson, Ann-Sofie Lantz, Kjell Larsson, Barbro Dahlén
Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study
Firdaus AA Mohamed Hoesein, Pieter Zanen, Pim A de Jong, Bram van Ginneken, H Marike Boezen, Harry JM Groen, Mathijs Oudkerk, Harry J de Koning, Dirkje S Postma, Jan-Willem J Lammers
Critical role of aldehydes in cigarette smoke-induced acute airway inflammation
Marco van der Toorn, Dirk-Jan Slebos, Harold G de Bruin, Renee Gras, Delaram Rezayat, Lucie Jorge, Koen Sandra, Antoon JM van Oosterhout
Diagnosis of chronic obstructive pulmonary disease in lung cancer screening Computed Tomography scans: independent contribution of emphysema, air trapping and bronchial wall thickening
Onno M Mets, Michael Schmidt, Constantinus F Buckens, Martijn J Gondrie, Ivana Isgum, Matthijs Oudkerk, Rozemarijn Vliegenthart, Harry J de Koning, Carlijn M van der Aalst, Mathias Prokop, Jan-Willem J Lammers, Pieter Zanen, Firdaus A Mohamed Hoesein, Willem PThM Mali, Bram van Ginneken, Eva M van Rikxoort, Pim A de Jong
Long-acting beta-agonists reduce mortality of patients with severe and very severe chronic obstructive pulmonary disease: a propensity score matching study
Nobuyuki Horita, Naoki Miyazawa, Satoshi Morita, Ryota Kojima, Naoko Kimura, Takeshi Kaneko, Yoshiaki Ishigatsubo
COPD and disease-specific health status in a working population
Koichi Nishimura, Satoshi Mitsuma, Atsuko Kobayashi, Mikako Yanagida, Kazuhito Nakayasu, Yoshinori Hasegawa, Paul W Jones
The drug efflux pump Pgp1 in pro-inflammatory lymphocytes is a target for novel treatment strategies in COPD
Greg Hodge, Mark Holmes, Hubertus Jersmann, Paul N Reynolds, Sandra Hodge
Nocturnal CPAP improves walking capacity in COPD patients with obstructive sleep apnoea
Tsai-Yu Wang, Yu-Lun Lo, Kang-Yun Lee, Wen-Te Liu, Shu-Min Lin, Ting-Yu Lin, Yung-Lun Ni, Chao-Yung Wang, Shu-Chuan Ho, Han-Pin Kuo
A probabilistic model of biological ageing of the lungs for analysing the effects of smoking, asthma and COPD
Silvia Chiappa, John Winn, Ana Viñuela, Hannah Tipney, Timothy David Spector
Efficacy and safety of AZD3199 vs formoterol in COPD: a randomized, double-blind study
Piotr Kuna, Yavor Ivanov, Vasily Ivanovich Trofimov, Takefumi Saito, Ola Beckman, Thomas Bengtsson, Carin Jorup, François Maltais
The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease
Qin Wang, Yunshan Wang, Yi Zhang, Yuke Zhang, Wei Xiao
NF-κB activation in myeloid cells mediates ventilator-induced lung injury
Yi-An Ko, Ming-Chieh Yang, Hung-Tu Huang, Ching-Mei Hsu, Lee-Wei Chen
RFX3 Modulation of FOXJ1 regulation of cilia genes in the human airway epithelium
Lukas Didon, Rachel K Zwick, Ion Wa Chao, Matthew S Walters, Rui Wang, Neil R Hackett, Ronald G Crystal
Differential response of BDCA-1+ and BDCA-3+myeloid dendritic cells to respiratory syncytial virus infection
Meera R Gupta, Deepthi Kolli, Roberto P Garofalo
Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27kip1 and FoxO3a
Stephen E McGowan, Diann M McCoy
Interleukin-6 and statin therapy: potential role in the management of COPD
Robert P Young, Raewyn J Hopkins
High prevalence of asthma symptoms in Warao Amerindian children in Venezuela is significantly associated with open-fire cooking: a cross-sectional observational study
Stèphan Kraai, Lilly M Verhagen, Enrique Valladares, Joaquin Goecke, Lorena Rasquin, Paula Colmenares, Berenice Del Nogal, Peter WM Hermans, Jacobus H de Waard
Neutrophil adhesion molecules in experimental rhinovirus infection in COPD
Patrick Mallia, Simon D Message, Marco Contoli, Katrina K Gray, Aurica Telcian, Vasile Laza-Stanca, Alberto Papi, Luminita A Stanciu, Sarah Elkin, Onn M Kon, Malcolm Johnson, Sebastian L Johnston
Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry
Laurent Bertoletti, Sara Quenet, Silvy Laporte, Joan Carles Sahuquillo, Francisco Conget, José María Pedrajas, Mar Martin, Ignacio Casado, Antonio Riera-Mestre, Manuel Monreal
Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials
Harold R Collard, Eric Yow, Luca Richeldi, Kevin J Anstrom, Craig Glazer
Factors associated with change in exacerbation frequency in COPD
Gavin C Donaldson, Hanna Müllerova, Nicholas Locantore, John R Hurst, Peter MA Calverley, Jorgen Vestbo, Antonio Anzueto, Jadwiga A Wedzicha
Fibroblasts: the missing link between fibrotic lung diseases of different etiologies?
Bruno Crestani, Valerie Besnard, Laurent Plantier, Keren Borensztajn, Arnaud Mailleux
Elimination of Aspergillus fumigatus conidia from the airways of mice with allergic airway inflammation
Marina A Shevchenko, Elena L Bolkhovitina, Ekaterina A Servuli, Alexander M Sapozhnikov
HTR4 gene structure and altered expression in the developing lung
Emily Hodge, Carl P Nelson, Suzanne Miller, Charlotte K Billington, Ceri E Stewart, Caroline Swan, Anders Malarstig, Amanda P Henry, Catherine Gowland, Erik Melén, Ian P Hall, Ian Sayers
Increased number and altered phenotype of lymphatic vessels in peripheral lung compartments of patients with COPD
Michiko Mori, Cecilia K Andersson, Gerard J Graham, Claes-Göran Löfdahl, Jonas S Erjefält
GST-omega genes interact with environmental tobacco smoke on adult level of lung function
Kim de Jong, H Marike Boezen, Nick HT ten Hacken, Dirkje S Postma, Judith M Vonk
Myofibroblast expression in airways and alveoli is affected by smoking and COPD
Henna M Karvonen, Siri T Lehtonen, Terttu Harju, Raija T Sormunen, Elisa Lappi-Blanco, Johanna M Mäkinen, Kirsi Laitakari, Shirley Johnson, Riitta L Kaarteenaho
Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons
Esther Klaile, Tilman E Klassert, Inka Scheffrahn, Mario M Müller, Annina Heinrich, Kerstin A Heyl, Hendrik Dienemann, Christiane Grünewald, Robert Bals, Bernhard B Singer, Hortense Slevogt
Pyocyanin-induced mucin production is associated with redox modification of FOXA2
Yonghua Hao, Zhizhou Kuang, Ying Xu, Brent E Walling, Gee W Lau
Adjunctive steroid in HIV-negative patients with severe Pneumocystis pneumonia
Virginie Lemiale, Alexandre Debrumetz, Alexandra Delannoy, Corinne Alberti, Elie Azoulay
Differential regulation of cell functions by CSD peptide subdomains
Charles Reese, Shanice Dyer, Beth Perry, Michael Bonner, James Oates, Ann Hofbauer, William Sessa, Pascal Bernatchez, Richard P Visconti, Jing Zhang, Corey M Hatfield, Richard M Silver, Stanley Hoffman, Elena Tourkina
Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease
Gisela E Lindahl, Carmel JW Stock, Xu Shi-Wen, Patricia Leoni, Piersante Sestini, Sarah L Howat, George Bou-Gharios, Andrew G Nicholson, Christopher P Denton, Jan C Grutters, Toby M Maher, Athol U Wells, David J Abraham, Elisabetta A Renzoni
The dopamine D1receptor is expressed and facilitates relaxation in airway smooth muscle
Kentaro Mizuta, Yi Zhang, Dingbang Xu, Fumiko Mizuta, Frank D’Ovidio, Eiji Masaki, Charles W Emala
Modulation of respiratory dendritic cells during Klebsiella pneumonia infection
Holger Hackstein, Sabine Kranz, Anne Lippitsch, Andreas Wachtendorf, Olivia Kershaw, Achim D Gruber, Gabriela Michel, Jürgen Lohmeyer, Gregor Bein, Nelli Baal, Susanne Herold
Aggravation of myocardial dysfunction by injurious mechanical ventilation in LPS-induced pneumonia in rats
Lonneke Smeding, Jan Willem Kuiper, Frans B Plötz, Martin CJ Kneyber, AB Johan Groeneveld
A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma
Chad K Oh, Richard Leigh, Kimmie K McLaurin, Keunpyo Kim, Micki Hultquist, Nestor A Molfino
Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells
Magdalena H Hudy, David Proud
The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells
Mitsuhiro Yamada, Hiroshi Kubo, Chiharu Ota, Toru Takahashi, Yukiko Tando, Takaya Suzuki, Naoya Fujino, Tomonori Makiguchi, Kiyoshi Takagi, Takashi Suzuki, Masakazu Ichinose
Obstructive lung diseases and inhaler treatment: results from a national public pragmatic survey
Fulvio Braido, Ilaria Baiardini, Massimo Sumberesi, Francesco Blasi, Giorgio Walter Canonica
Ceramides: a potential therapeutic target in pulmonary emphysema
Jeroen Tibboel, Irwin Reiss, Johan C de Jongste, Martin Post
Transposable elements and their potential role in complex lung disorder
Muralidharan Sargurupremraj, Matthias Wjst
Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice
Wei Liu, Jing Wan, Jian-Zhong Han, Chen Li, Dan-Dan Feng, Shao-Jie Yue, Yan-Hong Huang, Yi Chen, Qing-Mei Cheng, Yang Li, Zi-Qiang Luo
Role of Abl in airway hyperresponsiveness and airway remodeling
Rachel A Cleary, Ruping Wang, Tao Wang, Dale D Tang
Acrolein exposure suppresses antigen-induced pulmonary inflammation
Page C Spiess, David Kasahara, Aida Habibovic, Milena Hristova, Matthew J Randall, Matthew E Poynter, Albert van der Vliet
Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells
Roland F Hoffmann, Sina Zarrintan, Simone M Brandenburg, Arjan Kol, Harold G de Bruin, Shabnam Jafari, Freark Dijk, Dharamdajal Kalicharan, Marco Kelders, Harry R Gosker, Nick HT ten Hacken, Johannes J van der Want, Antoon JM van Oosterhout, Irene H Heijink
Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation
Duane R Winden, Nicholas T Ferguson, Benjamin R Bukey, Alexander J Geyer, Alex J Wright, Zac R Jergensen, Adam B Robinson, Jeffrey A Stogsdill, Paul R Reynolds
Estimating the U.S. prevalence of chronic obstructive pulmonary disease using pre- and post-bronchodilator spirometry: the National Health and Nutrition Examination Survey (NHANES) 2007–2010
Timothy Tilert, Charles Dillon, Ryne Paulose-Ram, Eva Hnizdo, Brent Doney
Improving medication adherence in chronic obstructive pulmonary disease: a systematic review
Jamie Bryant, Vanessa M McDonald, Allison Boyes, Rob Sanson-Fisher, Christine Paul, Jessica Melville
Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1 -/- mice
Kelsa E Gabehart, Simon G Royce, Diego J Maselli, Shelley K Miyasato, Elaine C Davis, Mimi LK Tang, Claude Jourdan Le Saux
Pulmonary biomarkers in COPD exacerbations: a systematic review
Angela Koutsokera, Konstantinos Kostikas, Laurent P Nicod, Jean-William Fitting
Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: I. Effects on lung remodeling and pathology
Hoeke A Baarsma, Sophie Bos, Herman Meurs, Kim H Visser, Marieke Smit, Annemie MWJ Schols, Ramon C Langen, Huib AM Kerstjens, Reinoud Gosens
Comparative efficacy of long-acting bronchodilators for COPD - a network meta-analysis
Shannon Cope, James F Donohue, Jeroen P Jansen, Matthias Kraemer, Gorana Capkun-Niggli, Michael Baldwin, Felicity Buckley, Alexandra Ellis, Paul Jones
COPD symptoms in the morning: impact, evaluation and management
Nicolas Roche, Niels H Chavannes, Marc Miravitlles
IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells
Jill R Johnson, Michiyoshi Nishioka, Jamila Chakir, Paul-André Risse, Ibrahim Almaghlouth, Ahmad N Bazarbashi, Sophie Plante, James G Martin, David Eidelman, Qutayba Hamid
Role of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD)
Sukhwinder Singh Sohal, Eugene Haydn Walters
Interferon-inducible chemokines reflect severity and progression in sarcoidosis
Robert Su, Michelle-Linh T Nguyen, Misha R Agarwal, Christopher Kirby, Christine P Nguyen, Joris Ramstein, Eli P Darnell, Antonio D Gomez, Melissa Ho, Prescott G Woodruff, Laura L Koth
Nicotine exposure during differentiation causes inhibition of N-myc expression
Ahmi Ben-Yehudah, Becki M Campanaro, Laura M Wakefield, Tia N Kinney, Jill Brekosky, Vonya M Eisinger, Carlos A Castro, Diane L Carlisle
α1-antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice
Di Jiang, Rebecca Persinger, Qun Wu, Ashley Gross, Hong Wei Chu
Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle
David Van Ly, Monique De Pedro, Peter James, Lucy Morgan, Judith L Black, Janette K Burgess, Brian GG Oliver
Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats
May Khin Hnin Si, Chieko Mitaka, Miniwan Tulafu, Shinya Abe, Masanobu Kitagawa, Satoshi Ikeda, Yoshinobu Eishi, Shunichi Kurata, Makoto Tomita
Physical activity level and its clinical correlates in chronic obstructive pulmonary disease: a cross-sectional study
Mikael Andersson, Frode Slinde, Anne Marie Grönberg, Ulla Svantesson, Christer Janson, Margareta Emtner
Azithromycin and cough-specific health status in patients with chronic obstructive pulmonary disease and chronic cough: a randomised controlled trial
Farida F Berkhof, Nynke E Doornewaard-ten Hertog, Steven M Uil, Huib AM Kerstjens, Jan WK van den Berg
LysoTracker is a marker of differentiated alveolar type II cells
Joanne L Van der Velden, Ivan Bertoncello, Jonathan L McQualter
Efficacy of a Carrageenan nasal spray in patients with common cold: a randomized controlled trial
Martin Ludwig, Elisabeth Enzenhofer, Sven Schneider, Margit Rauch, Angelika Bodenteich, Kurt Neumann, Eva Prieschl-Grassauer, Andreas Grassauer, Thomas Lion, Christian A Mueller
Associations between COPD related manifestations: a cross-sectional study
Elisabeth APM Romme, David A McAllister, John T Murchison, Edwin JR Van Beek, George S Petrides, Cameron OS Price, Erica PA Rutten, Frank WJM Smeenk, Emiel FM Wouters, William MacNee
Computer quantification of airway collapse on forced expiration to predict the presence of emphysema
Marko Topalovic, Vasileios Exadaktylos, Anneleen Peeters, Johan Coolen, Walter Dewever, Martijn Hemeryck, Pieter Slagmolen, Karl Janssens, Daniel Berckmans, Marc Decramer, Wim Janssens
Respiratory mechanics and ventilatory control in overlap syndrome and obesity hypoventilation
Johan Verbraecken, Walter T McNicholas
Circulating levels of copeptin predict outcome in patients with pulmonary arterial hypertension
Nils P Nickel, Ralf Lichtinghagen, Heiko Golpon, Karen M Olsson, Korbinian Brand, Tobias Welte, Marius M Hoeper
Serum heat shock protein 47 levels in patients with drug-induced lung disease
Tomoyuki Kakugawa, Shin-ichi Yokota, Yuji Ishimatsu, Tomayoshi Hayashi, Shota Nakashima, Shintaro Hara, Noriho Sakamoto, Yasuhiro Matsuoka, Hiroshi Kubota, Mariko Mine, Hiroshi Mukae, Kazuhiro Nagata, Shigeru Kohno
Role of IGF-1 pathway in lung fibroblast activation
Chi F Hung, Maryam G Rohani, Sung-soon Lee, Peter Chen, Lynn M Schnapp
The expression and relaxant effect of bitter taste receptors in human bronchi
Stanislas Grassin-Delyle, Charlotte Abrial, Sarah Fayad-Kobeissi, Marion Brollo, Christophe Faisy, Jean-Claude Alvarez, Emmanuel Naline, Philippe Devillier
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity
Matthew S Walters, Kazunori Gomi, Beth Ashbridge, Malcolm A S Moore, Vanessa Arbelaez, Jonna Heldrich, Bi-Sen Ding, Shahin Rafii, Michelle R Staudt, Ronald G Crystal
Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist
Brian R Leaker, Peter J Barnes, Brian O’Connor
Galectin-3: its role in asthma and potential as an anti-inflammatory target
Peng Gao, Jodie L Simpson, Jie Zhang, Peter G Gibson
Treatment and outcome of patients with metastatic NSCLC: a retrospective institution analysis of 493 patients
Niels Reinmuth, Nadine Payer, Thomas Muley, Hans Hoffmann, Felix JF Herth, Matthias Villalobos, Michael Thomas
Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
Sidra M Hoffman, Jane E Tully, James D Nolin, Karolyn G Lahue, Dylan H Goldman, Nirav Daphtary, Minara Aliyeva, Charles G Irvin, Anne E Dixon, Matthew E Poynter, Vikas Anathy
The unique alterations of hippocampus and cognitive impairment in chronic obstructive pulmonary disease
Jing Li, Guang-He Fei
Intrinsic predisposition of naïve cystic fibrosis T cells to differentiate towards a Th17 phenotype
Rahul Kushwah, Stéphane Gagnon, Neil B Sweezey
Anxiety and depression disorders in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
Dominik Harzheim, Hans Klose, Fabiola Peña Pinado, Nicola Ehlken, Christian Nagel, Christine Fischer, Ardeschir Ghofrani, Stephan Rosenkranz, Hans-Jürgen Seyfarth, Michael Halank, Eckhard Mayer, Ekkehard Grünig, Stefan Guth
The role of the liver X receptor in chronic obstructive pulmonary disease
Andrew Higham, Simon Lea, Jonathan Plumb, Barbara Maschera, Karen Simpson, David Ray, Dave Singh
Fluticasone impact on airway dendritic cells in smokers: a randomized controlled trial
Marek Lommatzsch, Ulrike Kraeft, Laura Troebs, Katharina Garbe, Andrea Bier, Paul Stoll, Sebastian Klammt, Michael Kuepper, Kai Bratke, Johann Christian Virchow
Improving physical activity in COPD: towards a new paradigm
Thierry Troosters, Thys van der Molen, Michael Polkey, Roberto A Rabinovich, Ioannis Vogiatzis, Idelle Weisman, Karoly Kulich
Characterisation of exacerbation risk and exacerbator phenotypes in the POET-COPD trial
Kai M Beeh, Thomas Glaab, Susanne Stowasser, Hendrik Schmidt, Leonardo M Fabbri, Klaus F Rabe, Claus F Vogelmeier
Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy
Koen JP Verhees, Nicholas AM Pansters, Hoeke A Baarsma, Alexander HV Remels, Astrid Haegens, Chiel C de Theije, Annemie MWJ Schols, Reinoud Gosens, Ramon CJ Langen
Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses
Yury A Bochkov, William W Busse, Rebecca A Brockman-Schneider, Michael D Evans, Nizar N Jarjour, Christopher McCrae, Anna Miller-Larsson, James E Gern