Issue 1/2007
Content (93 Articles)
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an α-smooth muscle actin-Cre transgenic mouse
Zhuang Wu, Leilei Yang, Lin Cai, Min Zhang, Xuan Cheng, Xiao Yang, Jun Xu
Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study
Medea Imboden, Sara H Downs, Oliver Senn, Gabor Matyas, Otto Brändli, Erich W Russi, Christian Schindler, Ursula Ackermann-Liebrich, Wolfgang Berger, Nicole M Probst-Hensch
The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model
María del Mar García-Suárez, Noelia Flórez, Aurora Astudillo, Fernando Vázquez, Roberto Villaverde, Kevin Fabrizio, Liise-Anne Pirofski, Francisco J Méndez
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs
Ralph T Schermuly, Soni S Pullamsetti, Susanne C Breitenbach, Norbert Weissmann, Hossein A Ghofrani, Friedrich Grimminger, Sigrid M Nilius, Karsten Schrör, Jutta Meger-Kirchrath, Werner Seeger, Frank Rose
Isoniazid prophylaxis differently modulates T-cell responses to RD1-epitopes in contacts recently exposed to Mycobacterium tuberculosis: a pilot study
Delia Goletti, M Pasquale Parracino, Ornella Butera, Federica Bizzoni, Rita Casetti, Duilio Dainotto, Gianfranco Anzidei, Carla Nisii, Giuseppe Ippolito, Fabrizio Poccia, Enrico Girardi
Human metapneumovirus induces more severe disease and stronger innate immune response in BALB/c mice as compared with respiratory syncytial virus
Barbara Huck, Dieter Neumann-Haefelin, Annette Schmitt-Graeff, Markus Weckmann, Jörg Mattes, Stephan Ehl, Valeria Falcone
Body composition and functional limitation in COPD
Mark D Eisner, Paul D Blanc, Steve Sidney, Edward H Yelin, Phenius V Lathon, Patricia P Katz, Irina Tolstykh, Lynn Ackerson, Carlos Iribarren
Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice
William Raoul, Orianne Wagner-Ballon, Guitanouch Saber, Anne Hulin, Elisabeth Marcos, Stéphane Giraudier, William Vainchenker, Serge Adnot, Saadia Eddahibi, Bernard Maitre
Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D
Kevan L Hartshorn, Mitchell R White, Tesfaldet Tecle, Ida Tornoe, Grith L Sorensen, Erika C Crouch, Uffe Holmskov
Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis
Brian D Gelbman, Adriana Heguy, Timothy P O'Connor, Joseph Zabner, Ronald G Crystal
An integrated approach to diagnosis and management of severe haemoptysis in patients admitted to the intensive care unit: a case series from a referral centre
Muriel Fartoukh, Antoine Khalil, Laurence Louis, Marie-France Carette, Bernard Bazelly, Jacques Cadranel, Charles Mayaud, Antoine Parrot
Impact on respiratory tract infections of heptavalent pneumococcal conjugate vaccine administered at 3, 5 and 11 months of age
Susanna Esposito, Alessandro Lizioli, Annalisa Lastrico, Enrica Begliatti, Alessandro Rognoni, Claudia Tagliabue, Laura Cesati, Vittorio Carreri, Nicola Principi
Surfactant disaturated-phosphatidylcholine kinetics in acute respiratory distress syndrome by stable isotopes and a two compartment model
Paola E Cogo, Gianna Maria Toffolo, Carlo Ori, Andrea Vianello, Marco Chierici, Antonina Gucciardi, Claudio Cobelli, Aldo Baritussio, Virgilio P Carnielli
Reference values of Forced Expiratory Volumes and pulmonary flows in 3–6 year children: a cross-sectional study
Pavilio Piccioni, Alberto Borraccino, Maria Pia Forneris, Enrica Migliore, Carlo Carena, Elisabetta Bignamini, Stefania Fassio, Giorgio Cordola, Walter Arossa, Massimiliano Bugiani
Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
Renate Paddenberg, Philipp Stieger, Anna-Laura von Lilien, Petra Faulhammer, Anna Goldenberg, Harald H Tillmanns, Wolfgang Kummer, Ruediger C Braun-Dullaeus
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
Lena Uller, Jesper Mosolff Mathiesen, Lisa Alenmyr, Magnus Korsgren, Trond Ulven, Thomas Högberg, Gunnar Andersson, Carl GA Persson, Evi Kostenis
Expression of Toll-like Receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis
Mattias Fransson, Mikael Benson, Jonas S Erjefält, Lennart Jansson, Rolf Uddman, Sven Björnsson, Lars-Olaf Cardell, Mikael Adner
Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease
Juan P de Torres, Ciro Casanova, Angela Montejo de Garcini, Armando Aguirre-Jaime, Bartolome R Celli
Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials
Sarah Haney, Robert J Hancox
Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?
Tamara Schikowski, Dorothea Sugiri, Ulrich Ranft, Ulrike Gehring, Joachim Heinrich, H-Erich Wichmann, Ursula Krämer
The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice
Hossein Koohsari, Meiyo Tamaoka, Holly R Campbell, James G Martin
Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD
Hiroshi Kanazawa, Kazuhisa Asai, Saeko Nomura
Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts
Giampiero La Rocca, Rita Anzalone, Francesca Magno, Felicia Farina, Francesco Cappello, Giovanni Zummo
Resolution of LPS-induced airway inflammation and goblet cell hyperplasia is independent of IL-18
J Foster Harris, Jay Aden, C Rick Lyons, Yohannes Tesfaigzi
A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease
Nicholas S Hopkinson, Rachel C Tennant, Mark J Dayer, Elisabeth B Swallow, Trevor T Hansel, John Moxham, Michael I Polkey
Validation of a guideline-based composite outcome assessment tool for asthma control
Sally Spencer, Bhabita Mayer, Kate L Bendall, Eric D Bateman
Stimulation of MAP kinase pathways after maternal IL-1β exposure induces fetal lung fluid absorption in guinea pigs
Reshma Bhattacharjee, Tianbo Li, Shyny Koshy, LaMonta L Beard, Kapil Sharma, Ethan P Carter, Chrystelle Garat, Hans G Folkesson
Nitric oxide induces MUC5AC mucin in respiratory epithelial cells through PKC and ERK dependent pathways
Jeong Sup Song, Chun Mi Kang, Moon Bin Yoo, Seung Joon Kim, Hyung Kyu Yoon, Young Kyoon Kim, Kwan Hyung Kim, Hwa Sik Moon, Sung Hak Park
IL-1β induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism
Yaping Zhang, Lars-Olaf Cardell, Mikael Adner
Exacerbations of chronic obstructive pulmonary disease: when are antibiotics indicated? A systematic review
Milo A Puhan, Daniela Vollenweider, Tsogyal Latshang, Johann Steurer, Claudia Steurer-Stey
Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells
Seijitsu Ando, Hitomi Otani, Yasuhiro Yagi, Kenzo Kawai, Hiromasa Araki, Shirou Fukuhara, Chiyoko Inagaki
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics
Sushma Komakula, Sumita Khatri, Joel Mermis, Samira Savill, Shireen Haque, Mauricio Rojas, LouAnn Brown, Gerald W Teague, Fernando Holguin
In-vivo kinetics of inhaled 5-Aminolevulinic acid-Induced Protoporphyrin IX fluorescence in bronchial tissue
Hubert Hautmann, Josef P Pichler, Herbert Stepp, Reinhold Baumgartner, Fernando Gamarra, Rudolf M Huber
Genomic analysis of human lung fibroblasts exposed to vanadium pentoxide to identify candidate genes for occupational bronchitis
Jennifer L Ingram, Aurita Antao-Menezes, Elizabeth A Turpin, Duncan G Wallace, James B Mangum, Linda J Pluta, Russell S Thomas, James C Bonner
Anti-inflammatory properties of desipramine and fluoxetine
Caroline Roumestan, Alain Michel, Florence Bichon, Karine Portet, Maëlle Detoc, Corinne Henriquet, Dany Jaffuel, Marc Mathieu
Alterations in cytoskeletal and immune function-related proteome profiles in whole rat lung following intratracheal instillation of heparin
Amir A Gabr, Mathew Reed, Donna R Newman, Jan Pohl, Jody Khosla, Philip L Sannes
Antisense oligonucleotide inhibition of Heat Shock Protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats
Satoshi Hagiwara, Hideo Iwasaka, Shigekiyo Matsumoto, Takayuki Noguchi
Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection
Paul Rennie, Philip Bowtell, David Hull, Duane Charbonneau, Robert Lambkin-Williams, John Oxford
Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa
Daniel Tetaert, Maud Pierre, Dominique Demeyer, Marie-Odile Husson, Laurent Béghin, Claude Galabert, Frédéric Gottrand, Christopher Beermann, Benoit Guery, Jean-Luc Desseyn
Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung
Mario Rüdiger, Sebastian Wendt, Lars Köthe, Wolfram Burkhardt, Roland R Wauer, Matthias Ochs
Azithromycin in the extremely low birth weight infant for the prevention of Bronchopulmonary Dysplasia: a pilot study
Hubert O Ballard, Michael I Anstead, Lori A Shook
AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid
Kondwani C Jambo, Neil French, Ed Zijlstra, Stephen B Gordon
A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy
Dagmar S Lang, Daniel Droemann, Holger Schultz, Detlev Branscheid, Christian Martin, Anne R Ressmeyer, Peter Zabel, Ekkehard Vollmer, Torsten Goldmann
Control of mucosal virus infection by influenza nucleoprotein-specific CD8+ cytotoxic T lymphocytes
Innocent N Mbawuike, Yongxin Zhang, Robert B Couch
Efficacy and safety of tiotropium in COPD patients in primary care – the SPiRiva Usual CarE (SPRUCE) study
Daryl Freeman, Angela Lee, David Price
Salmeterol/fluticasone stable-dose treatment compared with formoterol/budesonide adjustable maintenance dosing: impact on health-related quality of life
David B Price, Angela E Williams, Sally Yoxall
Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation
Marcus Gereke, Lothar Gröbe, Silvia Prettin, Michael Kasper, Stefanie Deppenmeier, Achim D Gruber, Richard I Enelow, Jan Buer, Dunja Bruder
Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients
Terttu H Harju, Mirva J Peltoniemi, Paula H Rytilä, Ylermi Soini, Kaisa M Salmenkivi, Philip G Board, Lloyd W Ruddock, Vuokko L Kinnula
Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice
Margaretha van der Deen, Wim Timens, Hetty Timmer-Bosscha, Barry W van der Strate, Rik J Scheper, Dirkje S Postma, Elisabeth G de Vries, Huib A Kerstjens
Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury
Christian M Kähler, Jutta Wechselberger, Wolfgang Hilbe, Andreas Gschwendtner, Daniela Colleselli, Harald Niederegger, Eva-Maria Boneberg, Gilbert Spizzo, Albrecht Wendel, Eberhard Gunsilius, Josef R Patsch, Jürg Hamacher
IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17
Brian W Booth, Tracy Sandifer, Erika L Martin, Linda D Martin
Comparison of the effects of salmeterol/fluticasone propionate with fluticasone propionate on airway physiology in adults with mild persistent asthma
Catherine M Houghton, Naomi Lawson, Zoe L Borrill, Claire L Wixon, Sally Yoxall, Stephen J Langley, Ashley Woodcock, Dave Singh
Vascular endothelial growth factor: an angiogenic factor reflecting airway inflammation in healthy smokers and in patients with bronchitis type of chronic obstructive pulmonary disease?
Nikoletta Rovina, Andreas Papapetropoulos, Androniki Kollintza, Makrina Michailidou, Davina CM Simoes, Charis Roussos, Christina Gratziou
Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate
Anagnostis Valotis, Petra Högger
Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration
Reinhold Schmidt, Philipp Markart, Clemens Ruppert, Malgorzata Wygrecka, Tim Kuchenbuch, Dieter Walmrath, Werner Seeger, Andreas Guenther
Maternal allergic contact dermatitis causes increased asthma risk in offspring
Robert H Lim, Mohamed S Arredouani, Alexey Fedulov, Lester Kobzik, Cedric Hubeau
Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study
Ulrich Baumann, Kerstin Göcke, Britta Gewecke, Joachim Freihorst, Bernd Ulrich von Specht
Effects of simulated altitude (normobaric hypoxia) on cardiorespiratory parameters and circulating endothelial precursors in healthy subjects
Michele M Ciulla, Michela Cortiana, Ilaria Silvestris, Emanuela Matteucci, Elisa Ridolfi, Fabrizio Giofrè, Maddalena Zanardelli, Roberta Paliotti, Agostino Cortelezzi, Alberto Pierini, Fabio Magrini, Maria Alfonsina Desiderio
Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery
Craig P Hersh, Dawn L DeMeo, John J Reilly, Edwin K Silverman
Protective role of vascular endothelial growth factor in endotoxin-induced acute lung injury in mice
Hidefumi Koh, Sadatomo Tasaka, Naoki Hasegawa, Wakako Yamada, Mie Shimizu, Morio Nakamura, Makoto Yonemaru, Eiji Ikeda, Yoshiyuki Adachi, Seitaro Fujishima, Kazuhiro Yamaguchi, Akitoshi Ishizaka
Impaired cortical processing of inspiratory loads in children with chronic respiratory defects
Brigitte Fauroux, Francis Renault, Pierre Yves Boelle, Christine Donzel-Raynaud, Frédéric Nicot, Annick Clément, Christian Straus, Thomas Similowski
Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema
Mathieu C Morissette, Julie Parent, Julie Milot
Invasive and noninvasive methods for studying pulmonary function in mice
Thomas Glaab, Christian Taube, Armin Braun, Wayne Mitzner
Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study
Janet S Lee, Matthew R Rosengart, Venkateswarlu Kondragunta, Yingze Zhang, Jessica McMurray, Robert A Branch, Augustine MK Choi, Frank C Sciurba
In vitro metabolism of beclomethasone dipropionate, budesonide, ciclesonide, and fluticasone propionate in human lung precision-cut tissue slices
Ruediger Nave, Robyn Fisher, Nigel McCracken
Controversy surrounding the increased expression of TGFβ1 in asthma
Ynuk Bossé, Marek Rola-Pleszczynski
Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma
Ian Pavord, Ashley Woodcock, Debbie Parker, Leanne Rice
Salmeterol and cytokines modulate inositol-phosphate signalling in Human airway smooth muscle cells via regulation at the receptor locus
Natalie Smith, Claudia A Browning, Nathalie Duroudier, Ceri Stewart, Samantha Peel, Caroline Swan, Ian P Hall, Ian Sayers
Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant
Hanna Müller, Caroline End, Marcus Renner, Burkhard M Helmke, Nikolaus Gassler, Christel Weiss, Dominik Hartl, Matthias Griese, Mathias Hafner, Annemarie Poustka, Jan Mollenhauer, Johannes Poeschl
Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice
Lars Knudsen, Matthias Ochs, Rosemarie MacKay, Paul Townsend, Roona Deb, Christian Mühlfeld, Joachim Richter, Fabian Gilbert, Samuel Hawgood, Kenneth Reid, Howard Clark
LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms
Hugues Chanteux, Amélie C Guisset, Charles Pilette, Yves Sibille
CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo
Pascal Knuefermann, Georg Baumgarten, Alexander Koch, Markus Schwederski, Markus Velten, Heidi Ehrentraut, Jan Mersmann, Rainer Meyer, Andreas Hoeft, Kai Zacharowski, Christian Grohé
Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses
John M Nicholls, Anthony J Bourne, Honglin Chen, Yi Guan, JS Malik Peiris
Simian virus 40 vectors for pulmonary gene therapy
Luminita Eid, Zohar Bromberg, Mahmoud Abd EL-Latif, Evelyn Zeira, Ariella Oppenheim, Yoram G Weiss
Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation
Emanuela Mazzon, Salvatore Cuzzocrea
Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction
Ziemowit Zietkowski, Roman Skiepko, Maria M Tomasiak, Anna Bodzenta-Lukaszyk
Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27kip1
Maiko Kadowaki, Shiro Mizuno, Yoshiki Demura, Shingo Ameshima, Isamu Miyamori, Takeshi Ishizaki
Continuous monitoring of the bronchial epithelial lining fluid by microdialysis
Stig S Tyvold, Erik Solligård, Oddveig Lyng, Sigurd L Steinshamn, Sigurd Gunnes, Petter Aadahl
Differential epithelial expression of the putative innate immune molecule SPLUNC1 in Cystic Fibrosis
Lynne Bingle, Frances A Barnes, Simon S Cross, Doris Rassl, William A Wallace, Michael A Campos, Colin D Bingle
The role of IFN-γ in regulation of IFN-γ-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures
Maria Torvinen, Hinnah Campwala, Iain Kilty
Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD
Agne Babusyte, Kristina Stravinskaite, Jolanta Jeroch, Jan Lötvall, Raimundas Sakalauskas, Brigita Sitkauskiene
Factors affecting exhaled nitric oxide measurements: the effect of sex
D Robin Taylor, Piush Mandhane, Justina M Greene, Robert J Hancox, Sue Filsell, Christene R McLachlan, Avis J Williamson, Jan O Cowan, Andrew D Smith, Malcolm R Sears
Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice
Francesco Blasi, Stefano Aliberti, Luigi Allegra, Gioia Piatti, Paolo Tarsia, Jacobus M Ossewaarde, Vivienne Verweij, Frans P Nijkamp, Gert Folkerts
Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke
Ruth E MacRedmond, Catherine M Greene, Delbert R Dorscheid, Noel G McElvaney, Shane J O'Neill
Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study
Thérèse S Lapperre, Jacob K Sont, Annemarie van Schadewijk, Margot ME Gosman, Dirkje S Postma, Ingeborg M Bajema, Wim Timens, Thais Mauad, Pieter S Hiemstra
Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD
Gaetan Deslee, Sandra Dury, Jeanne M Perotin, Denise Al Alam, Fabien Vitry, Rachel Boxio, Sophie C Gangloff, Moncef Guenounou, François Lebargy, Abderrazzaq Belaaouaj
Characterization of the innate immune response to chronic aspiration in a novel rodent model
James Z Appel III, Sean M Lee, Matthew G Hartwig, Bin Li, Chong-Chao Hsieh, Edward Cantu III, Yonghan Yoon, Shu S Lin, William Parker, R Duane Davis
Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis
Harriet Corvol, Nadia Nathan, Celine Charlier, Katarina Chadelat, Philippe Le Rouzic, Olivier Tabary, Brigitte Fauroux, Alexandra Henrion-Caude, Josue Feingold, Pierre-Yves Boelle, Annick Clement
COPD diagnosis related to different guidelines and spirometry techniques
Lennart Nathell, Madelene Nathell, Per Malmberg, Kjell Larsson
Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma
Venkata R Narala, Rajesh Ranga, Monica R Smith, Aaron A Berlin, Theodore J Standiford, Nicholas W Lukacs, Raju C Reddy
Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice
Kristen Page, Kristin M Lierl, Nancy Herman, Marsha Wills-Karp
Health-related quality of life and long-term prognosis in chronic hypercapnic respiratory failure: a prospective survival analysis
Stephan Budweiser, Andre P Hitzl, Rudolf A Jörres, Kathrin Schmidbauer, Frank Heinemann, Michael Pfeifer
Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial
Aklak B Choudhury, Carolyn M Dawson, Hazel E Kilvington, Sandra Eldridge, Wai-Yee James, Jadwiga A Wedzicha, Gene S Feder, Chris J Griffiths