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Oncology

Editor's Choice

Advances in radionuclide therapies for neuroendocrine tumors

Open Access Neuroendocrine Tumor Review

What is the current role of peptide receptor radionuclide therapy in patients with advanced neuroendocrine tumors, and what combinations could enhance its efficacy?

Postoperative pembrolizumab improves OS in high-risk RCC

18-04-2024 Kidney Cancer News

Adjuvant treatment with pembrolizumab is associated with a significant survival benefit in individuals with high-risk renal cell carcinoma.

Vocal cord paralysis caused by metastasized endometrial cancer

Open Access Endometrial Cancer Case Study

The first case of vocal cord paralysis due to a mediastinal metastasis developing 16 years after the patient's endometrial cancer was treated by hysterectomy, external beam radiotherapy, and chemotherapy.

Novel therapies for glioblastoma

Free for a limited time Glioblastoma Review

Recent clinical trials in glioblastoma have investigated a wide variety of therapeutic options, such as targeted agents, immunotherapies, and vaccine-based therapies. Find out more in this review.

ADCs in cancer: key data for currently approved agents

Open Access Cancer Therapy Review

Delve into the efficacy and safety data for the antibody–drug conjugates currently approved by the US FDA across tumor types such as hematologic, genitourinary, and gynecologic cancers.

Unusual presentation and delayed diagnosis of cardiac angiosarcoma

Open Access Hemangiosarcoma Case Study

Primary cardiac angiosarcomas are very aggressive tumors that often present after metastatic spread. In this case, initial presentation with chest pain rapidly progressed to multiple solid tumors. 

Three-phase screening approach promising for prostate cancer

11-04-2024 Prostate Cancer News

The ProScreen trial points to the potential of a single round of prostate cancer screening involving a PSA test, a kallikrein panel, and an MRI scan.

A rare case of adult primary brain rhabdomyosarcoma

Open Access Rhabdomyosarcoma Case Study

Primary brain rhabdomyosarcoma primarily occurs in children, but this case in a 26-year-old sheds light on managing the condition in adults.

Viruses and hematologic malignancies

A thorough understanding of the relationship between viruses and hematologic cancers can help clinicians to deliver precise therapies and monitor potential complications.

Update on the management of bone metastases

Open Access Bone Metastasis Review

Familiarize yourself with the currently available conventional and advanced radiotherapy options for symptomatic and oligometastatic bone disease in people with cancer.

Coronary thrombectomy for a post-op MI after brain tumor resection

Open Access Myocardial Infarction Case Study

How should you react to an acute MI immediately after a craniotomy for tumor resection? Management of such patients requires carefully balancing the competing risks of myocardial ischemia and postoperative bleeding. 

Forgoing axillary surgery does not increase breast cancer recurrence

04-04-2024 Breast Cancer News

Completion axillary lymph node dissection can be avoided in patients with early-stage, node-negative breast cancer with one or two macrometastases, show phase 3 data.

Ovarian suppression in breast cancer

Open Access Breast Cancer Review

Ovarian function suppression plays a key role in the management of breast cancer, but it comes with potentially impactful and long-lasting side effects. Counselling and proactive management of these should be considered an essential part of survivorship care.

Novel therapeutic targets in AML

Open Access Acute Myeloid Leukemia Review

Many more targeted therapies are now available for people with AML, in both the newly diagnosed and relapsed/refractory settings. Learn about the genetic and protein targets, and their associated therapeutics, in this review.

ICI-induced insulin-dependent diabetes without islet autoantibodies

Diabetes Case Study

Rapidly progressive insulin-dependent diabetes in the absence of islet autoantibodies developed 2 years after starting treatment with the immune checkpoint inhibitor nivolumab.

Adding pembrolizumab to CRT boosts cervical cancer PFS

27-03-2024 Cervical Cancer News

Women with a new diagnosis of high-risk, locally advanced cervical cancer could benefit from the addition of pembrolizumab to standard chemoradiotherapy.

Profound hypotension induced by ICI treatment

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

Role of ctDNA in gynecologic malignancies

Although circulating tumor DNA analysis has not been adopted as widely in gynecologic cancers as in other tumor types, new research shows promise for diagnosis, prognosis, and prediction of recurrence.

Doxorubicin use may increase breast cancer risk in adult Hodgkin’s lymphoma survivors

20-03-2024 Hodgkin Lymphoma News

Adolescent and adult survivors of Hodgkin’s lymphoma have a higher risk for developing breast cancer if they receive doxorubicin than if they do not.

Severe megaloblastic anemia related to erlotinib

Open Access NSCLC Case Study

The first case of severe megaloblastic anemia in a patient treated with erlotinib for advanced NSCLC. It highlights the need for close clinical and blood monitoring in people receiving long-term TKI therapy.