Oncology

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

Learn about the rationale for using PARP inhibitors in the neoadjuvant treatment of various cancers with homologous recombination repair deficiency, as well as the ongoing clinical trials and future directions.

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

Bone metastases occur in 1–23% of gynecologic cancer patients. What are the available pharmacologic, surgical, and radiation treatments for palliation and the prevention of skeletal-related events in this population?

Although gastrointestinal adverse events were not uncommon in trials of the novel agent zolbetuximab, they tended to be transient. This is the first report of delayed-onset and persistent gastritis linked to its use.

Offering targeted screening based on a high polygenic risk score led to the detection of a high proportion of clinically significant prostate cancer in the BARCODE1 trial.

The changing landscape of NSCLC treatment provides numerous novel options, but how can they best be incorporated into clinical practice to improve patient outcomes?

A patient who received CAR T-cell therapy for refractory/relapsed multiple myeloma developed acute myeloid leukemia, highlighting the need for long-term and close monitoring after such treatment.

Immune checkpoint inhibitors have transformed the treatment of numerous cancer types, but they can cause significant toxicity and unusual patterns of progression. Delve into the good, the bad, and the ugly of these agents.

Up to 95% of cancer patients receiving radiotherapy develop acute radiation-induced dermatitis. Equip yourself to assess and manage this adverse event with these actionable, evidence-based recommendations.

Appendiceal tumors occur at a rate of 14.3% in patients with acute appendicitis and periappendicular abscess, supporting the argument for interval appendectomy after conservative management.

A 10-year-old boy exhibited persistent pancytopenia following treatment for mucormycosis, with further diagnosis revealing AML. Septic shock soon followed, but was successfully managed with combined CRRT and CytoSorb therapy.

Liver metastasis as the first clinical sign of parotid gland adenoid cystic carcinoma is very rare, but shows that salivary gland tumors should be considered in the differential diagnosis of unexplained hepatic lesions.

Patients requiring extended thromboprophylaxis after a first episode of cancer-related venous thromboembolism can be given a low dose of the factor X inhibitor apixaban.

Discover the latest insights on ocular symptoms and related physiopathology in MM. Can the eyes’ manifestations be considered a disease hallmark that can guide your decision-making?

The incidence of secondary neoplasia in patients with acromegaly has increased in recent years. What are the risk factors for cancer in these patients, which cancers are most common, and how should screening be approached?

What’s best practice for managing seizures in patients with primary brain tumors or brain metastases, or as a consequence of cancer therapy?

Using the NeuroSAFE technique to guide robot-assisted radical prostatectomy improves functional outcomes 12 months after surgery compared with standard preoperative nerve-sparing planning.

Explore the evolving landscape of HER2-targeted therapies for gastric cancer and learn about the efforts to overcome resistance to trastuzumab, low HER2 expression, and variability in testing.