Oncology

Primary cardiac angiosarcomas are very aggressive tumors that often present after metastatic spread. In this case, initial presentation with chest pain rapidly progressed to multiple solid tumors. 

Primary brain rhabdomyosarcoma primarily occurs in children, but this case in a 26-year-old sheds light on managing the condition in adults.

How should you react to an acute MI immediately after a craniotomy for tumor resection? Management of such patients requires carefully balancing the competing risks of myocardial ischemia and postoperative bleeding. 

Rapidly progressive insulin-dependent diabetes in the absence of islet autoantibodies developed 2 years after starting treatment with the immune checkpoint inhibitor nivolumab.

A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.

The first case of severe megaloblastic anemia in a patient treated with erlotinib for advanced NSCLC. It highlights the need for close clinical and blood monitoring in people receiving long-term TKI therapy.

Sciatica due to Streptococcus gallolyticus infection of the spinal epidural space led to a diagnosis of colorectal cancer in a person with none of the usual signs and symptoms.

A mediastinal angiosarcoma presented mimicking signs of constrictive pericarditis, aortic dissection, and coronary artery disease. The correct diagnosis only was made measurement of hyaluronic acid concentration in the pleural fluid.

A pancreatic neuroendocrine microtumor with a high proliferation rate but metabolic, genetic, and epigenetic features correlated with a less aggressive disease course highlights the need to better understand PanNET tumorigenesis.

A report of primary endobronchial melanoma that sheds light on the clinical presentation, histopathology, diagnostic challenges, and treatment options for this rare entity.

Although rare, primary thyroid lymphoma should be considered in cases of rapidly growing goiters. Timely needle biopsy can avoid unnecessary surgery.

A woman developed sudden painless ecchymosis (bruising) of her breast, which was thought to be related to the radiotherapy she received for early-stage breast cancer a year and a half earlier.

A patient receiving arsenic trioxide for acute promyelocytic leukemia developed drug-induced acute pericarditis that was successfully treated with colchicine.

Tumor-to-tumor metastasis is the most common extracranial cancer metastasis to existing brain tumors, whereas a rare form is metastasis infiltrating tumor. In this case, a lung cancer tumor metastasized adjacent to and partially infiltrated an existing meningioma.

Secretory carcinoma is generally considered a slow-growing, low-grade malignant tumor, but this report describes a patient with high-grade features who presented with a soft-tissue neck mass.

Nasopharyngeal carcinoma is known for its high potential to metastasize, but breast metastasis is rare. The authors describe the first case of synchronous breast metastases in a male patient.

Ectopic thyroid is very rarely found as a solitary tumor in the submandibular region, but it should be considered in the differential diagnosis when papillary structures are seen on histopathology.

Successful surgical resection of lung cancer arising in a transplanted lung, using venovenous extracorporeal membrane oxygenation to overcome the challenge of single-lung ventilation during the procedure. 

A case series of three patients suggests that obinutuzumab-induced acute thrombocytopenia is a frequent, possibly non-relapsing, and unique adverse event that deserves more attention than it currently receives.

Carcinosarcomas or malignant mixed tumors of the salivary gland are extremely rare. This report describes the first case of adenoid cystic carcinoma as the carcinomatous component with chondrosarcoma.