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European Journal of Medical Research
Published in: European Journal of Medical Research 1/2023

Open Access 01-12-2023 | Metastasis | Review

Combination of radiotherapy and targeted therapy for HER2-positive breast cancer brain metastases

Authors: Xiaojing Yang, Hanru Ren, Yi Xu, Xue Peng, Wenxi Yu, Zan Shen

Published in: European Journal of Medical Research | Issue 1/2023

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Abstract

Radiotherapy and targeted therapy are essential treatments for patients with brain metastases from human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, the combination of radiotherapy and targeted therapy still needs to be investigated, and neurotoxicity induced by radiotherapy for brain metastases has also become an important issue of clinical concern. It remained unclear how to achieve the balance of efficacy and toxicity with the application of new radiotherapy techniques and new targeted therapy drugs. This article reviews the benefits and potential risk of combining radiotherapy and targeted therapy for HER2-positive breast cancer with brain metastases.
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Metadata
Title
Combination of radiotherapy and targeted therapy for HER2-positive breast cancer brain metastases
Authors
Xiaojing Yang
Hanru Ren
Yi Xu
Xue Peng
Wenxi Yu
Zan Shen
Publication date
01-12-2023
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2023
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/s40001-022-00894-7

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