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Advances in Alzheimer’s

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition.

Published: Thursday 12th December 2024
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Endocrinology Metabolic Disease and Nutrition

Metabolic Disease and Nutrition

Poor muscle quality: a hidden health condition in obesity

Poor muscle quality is commonly underdiagnosed in people with obesity. Explore the definitions, assessment methods, associated health outcomes, and potential interventions.

Read more

Editor's Choice

Targeting ultra-processed foods for prevention of type 2 diabetes

The increasing availability and intake of UPFs is occurring alongside the rising incidence of obesity and type 2 diabetes. Examine the evidence linking UPFs with excess type 2 diabetes risk.

Racial disparities in HFpEF

HFpEF remains under-recognized in Black and Hispanic patients. Understand the inequities in diagnosis, management and healthcare access and what steps to take to better optimize care. 

SGLT2 inhibitor triggers metabolic encephalopathy

Testing ketone levels and brain MRI is essential for unconscious patients on SGLT2 inhibitors. Patients on these drugs are at increased risk of euglycemic diabetic ketoacidosis, which may cause metabolic encephalopathy.

Managing MASLD: the role of medical nutrition therapy

Medical nutrition therapy is a key intervention in the management of MASLD, but its success depends on a coordinated and continuous approach that is multidisciplinary and guided by the latest evidence.

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Episode 13: Advances in MASLD and MASH

Welcoming a new name and a new treatment

Metabolic dysfunction-associated liver disease is a significant healthcare concern and burden. Until recently there was no approved pharmacologic treatment for the more serious form of the disease, metabolic dysfunction-associated steatohepatitis. 

In this wide-ranging conversation, Prof. Vlad Ratziu explains the rationale behind the recently updated subclassification and nomenclature for steatotic liver disease, puts the therapeutic advance of resmetirom into context, and looks to the future for MASLD and MASH.

Prof. Vlad Ratziu
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Latest News

LDL-C genetic profiles predict type 2 diabetes risk

Increased fat within skeletal muscle raises risk for MACE

Screening for iron deficiency in women is cost-effective

Tirzepatide for heart failure with obesity

BMI may ‘misclassify’ metabolic disease risk among some healthy individuals

Severe CKD increases emergent hypocalcemia risks of denosumab in osteoporosis

Case Studies

SGLT2 inhibitor triggers metabolic encephalopathy

Testing ketone levels and brain MRI is essential for unconscious patients on SGLT2 inhibitors. Patients on these drugs are at increased risk of euglycemic diabetic ketoacidosis, which may cause metabolic encephalopathy.

Cholesterol crystal embolization following alteplase for stroke

CCE led to multiorgan failure and death after intravenous alteplase to treat acute ischemic stroke. This case highlights the urgent need for greater awareness of this serious complication.

Do GNB1 gene variants have a role in obesity?

Two rare cases that expand the list of pathogenic GNB1 variants. GNB1 may have value as a candidate gene for severe early-onset obesity, hyperphagia, and neurodevelopmental delay or other metabolic and endocrine disorders.

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
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Current Reviews

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges

Endometrial cancer (EC) is the sixth-most common cancer in women, with over 427,000 newly diagnosed cases globally in 2022 [ 1 ]. An increasing number of young patients are choosing to undergo fertility-preservation treatment. The guidelines …

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections

The prostate gland is an endocrine-sensitive organ responding to multiple stimuli. Its development and function are regulated by multiple hormones (i.e. steroids such as androgens, estrogens and glucocorticoids) but also by other key hormonal …

Challenges in blood pressure measurement in children with obesity: focus on the cuff

Childhood obesity is a well-known risk factor for primary hypertension (HTN), especially during puberty. Validated automated oscillometric devices based on universal protocols using proper cuffs according to arm sizes must be selected for blood …

The Efficacy of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists for Insufficient Weight Loss or Regain After Metabolic/Bariatric Surgery: A Systematic Review and Meta-analysis

Metabolic and bariatric surgery (MBS) is a successful surgical option for obesity. However, many patients can experience insufficient weight loss and weight regain post-operatively. Glucagon-like peptide-1 (GLP-1) receptor agonists have become …

Keynote webinar | Spotlight on diet and diabetes

  • Webinar | 08-11-2023 | 18:00 (CET)

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine
Watch now

CME & eLearning

Videos | Case Scenarios | Infographics (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)™

Refine the application of CGM technology in primary care to enhance the management of type 2 diabetes. Benefit from key updates and experiential learning using CGM devices, and practice your clinical decision-making skills.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)™

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Further Reading

Cardiovascular Risk Factors and Diseases and Awareness of Related Burden in Women: Results of a Survey in Italian Pharmacies

Cardiovascular diseases (CVD) represent the leading cause of death for women worldwide both during childbearing age and after menopause, and accounted for about 30% of total deaths in women in 2021 ([ 1 ] accessed 13 June, 2024; [ 2 ] accessed 13 …

A Population-Based Study of Bariatric Surgery Trends in Australia: Variations Reflect Continuing Inequities in Access to Surgery

Obesity affects approximately 20% of adults worldwide, and its prevalence continues to rise [ 1 ]. Obesity contributes significantly to the global burden of chronic disease, with cardiovascular disease being the leading cause of obesity-related …

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections

The prostate gland is an endocrine-sensitive organ responding to multiple stimuli. Its development and function are regulated by multiple hormones (i.e. steroids such as androgens, estrogens and glucocorticoids) but also by other key hormonal …

Menstrual and sexual functions in female patients after sleeve gastrectomy due to obesity: obesity and sexual function

  • Open Access
  • Obesity
  • General Gynecology

Obesity is defined as a body mass index (BMI) of 30 kg/m2 and above [ 1 ]. Obesity is a common health problem, associated with type 2 diabetes, hypertension, dyslipidemia, and ischemic heart disease [ 2 , 3 ]. It is reported to be the fifth leading …

Related topics

Poor muscle quality: a hidden health condition in obesity

Poor muscle quality is commonly underdiagnosed in people with obesity. Explore the definitions, assessment methods, associated health outcomes, and potential interventions.

Read more

Targeting ultra-processed foods for prevention of type 2 diabetes

Racial disparities in HFpEF

Managing MASLD: the role of medical nutrition therapy

Increased fat within skeletal muscle raises risk for MACE

The gut microbiota in obesity

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