Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.
Childhood obesity is a growing global health concern, but how should obesity be defined and measured in children, and how does it impact health in the short and long term?
Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.
Discover the growing evidence for incretin-based therapies in metabolic dysfunction-associated steatohepatitis, the potential mechanisms involved, common side effects, and what’s needed to finesse their use.
The metabolic accelerator HU6 leads to modest but significant weight loss in adults who have obesity and heart failure with preserved ejection fraction.
Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.
Although it seems to be a rare complication, there should be a high index of suspicion for colonic ischemia in patients taking a GLP-1 receptor agonist who present with abdominal pain.
Semaglutide therapy achieved weight loss and reduced cocaine craving in a man with obesity and chronic cocaine abuse. Could this be a new strategy to address substance craving in patients with comorbid obesity?
Two rare cases that expand the list of pathogenic GNB1 variants. GNB1 may have value as a candidate gene for severe early-onset obesity, hyperphagia, and neurodevelopmental delay or other metabolic and endocrine disorders.
We aimed to investigate the effect of primary Roux-en-Y gastric bypass (RYGB) on gastro-oesophageal reflux disease (GORD) in patients with obesity. A systematic review was performed using MEDLINE, Embase, Emcare, and CINAHL databases for studies …
Cardiovascular, kidney and metabolic (CKM) conditions are interrelated, significantly contributing to morbidity, mortality and healthcare burden. Despite therapeutic advances, traditional disease-specific approaches often fail to address their …
Obesity is a chronic disease causing a major public health challenge, particularly in Algeria, yet in patient referrals for metabolic/bariatric surgery (MBS), the most effective treatment remain low. This study aims to analyze the factors …
A recent international multi-society Delphi consensus statement on fatty liver disease nomenclature has established “steatotic liver disease” (SLD) as the term for disorders characterized by hepatic lipid accumulation [ 1 ]. Pediatric SLD includes …
An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.
With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.
This program is not available to users in the UK and US.
Treating children with hormone disorders is complex and requires tailored management. To help you provide the most effective care, we deliver resources covering adrenal, thyroid, pituitary, growth, and puberty disorders, obesity, and diabetes.
We aimed to investigate the effect of primary Roux-en-Y gastric bypass (RYGB) on gastro-oesophageal reflux disease (GORD) in patients with obesity. A systematic review was performed using MEDLINE, Embase, Emcare, and CINAHL databases for studies …
Metabolic and bariatric surgery (MBS) is a safe and effective treatment option for patients not responding to non-surgical treatments [ 1 – 3 ]. Despite its effectiveness, utilization of MBS among eligible patients with severe obesity (BMI ≥ 40) …
Obesity is a highly prevalent chronic disease in the UK, with nearly two-thirds of adults (63%) affected by either overweight or obesity [ 1 ]. Obesity challenges economic growth, costing approximately £27 billion yearly, which includes direct …
Inflammatory Bowel Disease (IBD), mainly consisting of ulcerative colitis (UC) and Crohn’s disease (CD), are chronic immune-mediated inflammatory diseases affecting the gastrointestinal tract. The etiology of IBD is multifactorial, involving a …
