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16-07-2024 Obesity News

Greater weight loss with tirzepatide than semaglutide

Treatment with tirzepatide leads to greater weight loss than semaglutide in people with overweight or obesity, regardless of type 2 diabetes.

Editor's Choice

Survodutide shows promise for treating MASH

Survodutide beats placebo at improving metabolic dysfunction–associated steatohepatitis without worsening fibrosis.

Tirzepatide shows promise for obstructive sleep apnea

Tirzepatide may reduce sleep apnea severity in people with moderate-to-severe obstructive sleep apnea and obesity, show data from the SURMOUNT-OSA phase 3 trials.

Therapies for co-existing asthma and obesity

Open Access Bronchial Asthma Review

Obesity is associated with increased incidence of asthma and worse outcomes. Explore the biologic and non-biologic treatment options for patients with asthma and obesity.

Tirzepatide shows promise for MASH

Tirzepatide may be a suitable treatment for metabolic dysfunction-associated steatohepatitis with moderate or severe fibrosis, show data from the phase 2 SYNERGY-NASH trial.

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Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Case Studies

Spontaneous remission of diabetes in a girl with systemic lupus erythematosus

Open Access Diabetes Case Study

A unique, reversible diabetes subtype, suggestive of an autoimmune origin, in a 14-year-old girl with obesity and SLE, who presented with ketoacidosis, elevated HbA1c and positive anti-insulin antibodies.

Restoring normal food passage in a patient with severe post-bariatric hypoglycemia

Open Access Bariatric Surgery Case Study

Successful laparoscopic reversal of RYGB in a patient who had undergone many bariatric revision surgeries and was experiencing severe, unresponsive post-bariatric hypoglycemia and daily neuroglycopenic seizures.

Webinar | 08-11-2023 | 18:00 (CET)

Keynote webinar | Spotlight on diet and diabetes

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Prof. Mike Lean
Prof. Falko Sniehotta
Developed by: Springer Medicine

Current Reviews

Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?

Open Access Obesity REVIEW

Atherosclerotic cardiovascular disease (ASCVD) is a prominent contributor to cardiovascular disease (CVD), which is one of the primary contributors of morbidity and mortality in modern society [ 1 ]. In Europe, it claims the lives of approximately …

Efficacy of Interval Training in Improving Body Composition and Adiposity in Apparently Healthy Adults: An Umbrella Review with Meta-Analysis

Open Access Obesity Systematic Review

The World Health Organization (WHO) defines excess weight and obesity as abnormal or excess fat accumulation that poses a risk to health. Obesity is an independent risk factor for various noncommunicable diseases, including heart disease, stroke …

Modern Management of Cardiometabolic Continuum: From Overweight/Obesity to Prediabetes/Type 2 Diabetes Mellitus. Recommendations from the Eastern and Southern Europe Diabetes and Obesity Expert Group

Open Access Type 2 Diabetes Review

The increasing global incidence of obesity and type 2 diabetes mellitus (T2D) underscores the urgency of addressing these interconnected health challenges. Obesity enhances genetic and environmental influences on T2D, being not only a primary risk …

Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds

Open Access Obesity REVIEW

In the era of convenience and abundance of ultra-processed foods, the Western diet has become embedded in our current society. Despite its popularity, the Western diet has been recognized as the major culprit of a more pressing matter – the global …

CME & eLearning

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Further Reading

Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice

Open Access Type 2 Diabetes Original Research

Obesity and type 2 diabetes (T2D) are risk factors for fragility fractures. It is unknown whether this elevated risk is due to a diet favoring obesity or the diabetes that often occurs with obesity. Therefore, we hypothesized that the fracture …

A comparison of brown fat tissue related hormone levels in metabolically healthy and unhealthy individuals with obesity

Open Access Obesity Original Article

In recent years, obesity has become an epidemic in both children and adults and, obesity-related diseases such as type 2 diabetes, cancer, and cardiovascular disease have also increased [ 1 ].

Core Set of Patient-Reported Outcome Measures for Measuring Quality of Life in Clinical Obesity Care

Open Access Obesity Original Contributions

Obesity is chronic and impairs patients’ health and well-being [ 1 , 2 ]. Treatment includes lifestyle interventions, medication, and metabolic and bariatric surgery [ 3 ]. Treatments can have a significant impact on weight and also on patients’ …

Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?

Open Access Obesity REVIEW

Atherosclerotic cardiovascular disease (ASCVD) is a prominent contributor to cardiovascular disease (CVD), which is one of the primary contributors of morbidity and mortality in modern society [ 1 ]. In Europe, it claims the lives of approximately …