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Medical Oncology

Issue 7/2023

Content (28 Articles)

NSCLC Original Paper

Depletion of enhancer zeste homolog 2 (EZH2) directs transcription factors associated with T cell differentiation through epigenetic regulation of Yin Yang 1(YY1) in combating non-small cell lung cancer (NSCLC)

Nikhil Chandnani, Vedika Shrirang Choudhari, Rajat Talukdar, Sudeshna Rakshit, Geetha Shanmugam, Shiuli Guchait, Ishika Gupta, Melvin George, Koustav Sarkar

Isorhamnetin exerts anti-tumor activity in DEN + CCl4-induced HCC mice

Sayanta Sarkar, Abhishek Kumar Das, Semantee Bhattacharya, Ratan Gachhui, Parames C. Sil

Open Access Lung Cancer Original Paper

β­caryophyllene oxide induces apoptosis and inhibits proliferation of A549 lung cancer cells

Sameh M. Shabana, Nahla S. Gad, Azza I. Othman, Aly Fahmy Mohamed, Mohamed Amr El-Missiry

Dexamethasone enhances venetoclax-induced apoptosis in acute myeloid leukemia cells

Haixia Wang, Junjie Zhou, Xiaoyu Ma, Changqing Jiao, Enbo Chen, Zhonghui Wu, Yan Zhang, Mengya Pan, Jianling Cui, Chengxin Luan, Jian Ge

Metformin Original Paper

A phase II study of metformin plus pemetrexed and carboplatin in patients with non-squamous non-small cell lung cancer (METALUNG)

S. Verma, S. Chitikela, V. Singh, S. Khurana, D. Pushpam, D. Jain, S. Kumar, Y. Gupta, P. S. Malik

Open Access Glioma Original Paper

Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target

Sourat Darabi, Joanne Xiu, Timothy Samec, Santosh Kesari, Jose Carrillo, Sonikpreet Aulakh, Kyle M. Walsh, Soma Sengupta, Ashley Sumrall, David Spetzler, Michael Glantz, Michael J. Demeure

Colorectal Cancer Original Paper

The crosstalk between ubiquitin-conjugating enzyme E2Q1 and p53 in colorectal cancer: An in vitro analysis

Maryam Rasouli, Sara Khakshournia, Omid Vakili, Sanaz Dastghaib, Atefeh Seghatoleslam, Sayed Mohammad Shafiee

Breast Cancer Original Paper

A network pharmacology-based investigation of brugine reveals its multi-target molecular mechanism against Breast Cancer

Hina Qayoom, Mustfa Alkhanani, Abdullah Almilaibary, Suliman A. Alsagaby, Manzoor A. Mir

Open Access Gefitinib Original Paper

Efficacy and safety of EGFR inhibitor gefitinib in recurrent or metastatic cervical cancer: a preliminary report

Abhishek Krishna, M. Sathya, S. Mukesh, M. S. Athiyamaan, Sourjya Banerjee, Johan Sunny, Challapalli Srinivas, Dilson Lobo, Bharat Sai Makkapatti, Vaishak Jawahar

Open Access Myelodysplastic Syndrome Original Paper

Circulating cancer giant cells with unique characteristics frequently found in patients with myelodysplastic syndromes (MDS)

Abdullah Mahmood Ali, Fatima BenMohamed, Alessandra Decina, Sanjay Mukherjee, Shelley Levi, Laura Nalleli Garrido Castillo, Davide Bréchot, Joseph Jurcic, Azra Raza, Patrizia Paterlini Bréchot

Original Paper

RUNX1/ETO regulates reactive oxygen species (ROS) levels in t(8,21) acute myeloid leukaemia via FLT3 and RAC1

Adam Azlan, Kang Zi Khor, Yaashini Rajasegaran, Aliaa Arina Rosli, Mohamed Saifulaman Mohamed Said, Narazah Mohd Yusoff, Emmanuel Jairaj Moses

Breast Cancer Original Paper

Racial and regional disparities in deaths in breast cancer

Akshita Khosla, Devashish Desai, Sachi Singhal, Aanchal Sawhney, Rashmika Potdar

Lung Cancer Original Paper

Identification of glycogen phosphorylase L as a potential target for lung cancer

Xin-Ling He, Wen-Yu Lyu, Xin-Yuan Li, Hong Zhao, Lu Qi, Jin-Jian Lu

Perspectives in Oncology

Current perspectives on Vaxinia virus: an immuno-oncolytic vector in cancer therapy

Simran Deep Kaur, Aman Deep Singh, Deepak N. Kapoor

Lenvatinib Review Article

The past, present, and future of immunotherapy for endometrial adenocarcinoma

Anna C. Jones, Karah H. Brown, Tianyun Guan, Luke A. Smith, Cole R. Formslag, Emerson D. Farjado, Qian Bai, Harrison D. Luechtefeld, Mark R. Wakefield, Lijun Dong, Yujiang Fang

Solid Tumor Review Article

Implications of IL-21 in solid tumor therapy

Seyed Hossein Abtahi Eivary, Ramiar Kamal Kheder, Soran K. Najmaldin, Nahid Kheradmand, Seyed-Alireza Esmaeili, Jafar Hajavi

Breast Cancer Review Article

Recent advancement of HDAC inhibitors against breast cancer

Syed Abdulla Mehmood, Kantrol Kumar Sahu, Sounok Sengupta, Sangh Partap, Rajshekhar Karpoormath, Brajesh Kumar, Deepak Kumar

Cancer Immunotherapy Review Article

The future of cancer immunotherapy: DNA vaccines leading the way

Aanshi Pandya, Yesha Shah, Nirjari Kothari, Humzah Postwala, Aayushi Shah, Priyajeet Parekh, Mehul R. Chorawala

Cancer Immunotherapy Review Article

NK cells direct the perspective approaches to cancer immunotherapy

Abduladheem Turki Jalil, Mohanad Ali Abdulhadi, Farah A. Al-Marzook, Manar Mohammed Hizam, Sada Jasim Abdulameer, Abdul Kareem J. Al-Azzawi, Rahman S. Zabibah, Ali A. Fadhil

Cancer Therapy Review Article

Current advances in microbial-based cancer therapies

Areej Shahbaz, Tehreem Mahmood, Muhammad Uzair Javed, Bilal Haider Abbasi

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine