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Lymphoma

Editor's Choice

Primary thyroid lymphoma: a case series

Open Access Thyroid Cancer Case Study

Although rare, primary thyroid lymphoma should be considered in cases of rapidly growing goiters. Timely needle biopsy can avoid unnecessary surgery.

Childhood cancer survivors benefit from getting active

08-02-2024 Pediatric Cancer News

Increasing intense physical activity levels over a year reduced fatigue among adult childhood cancer survivors enrolled in the SURfit trial.

Obinutuzumab-induced acute thrombocytopenia

Open Access Lymphoma Case Study

A case series of three patients suggests that obinutuzumab-induced acute thrombocytopenia is a frequent, possibly non-relapsing, and unique adverse event that deserves more attention than it currently receives.

Novel therapies for Richter’s transformation

Richter’s transformation is a rare complication of chronic lymphocytic leukemia that is associated with poor outcomes. The evolving landscape of its treatment is discussed in this review.

Primary central nervous system lymphoma

PCNSL is a B-cell non-Hodgkin lymphoma in the brain, spinal cord, CSF, or eyes, without systemic manifestations. Though relapses are common, PCNSL is treatable in most cases, making timely diagnosis and treatment essential.

Integrative approaches in the management of patients with lymphoma

Lymphoma Review

A wide range of complementary and integrative approaches are being studied in lymphoma and may prove beneficial for patients. But better patient–practitioner communication and systematic evaluation of potential safety issues are crucial.

Cauda equina syndrome caused by secondary CNS lymphoma

Open Access Diffuse Large B-Cell Lymphoma Case Study

Although cauda equina syndrome in the context of secondary CNS lymphoma is a rare occurrence, it should be considered in at-risk patients, especially those presenting with abnormal neurological findings.

Updates in the classification of T/NK-cell lymphomas and lymphoproliferative disorders

Lymphoma Review

Two new classification systems for T/NK-cell lymphomas and lymphoproliferative disorders were released recently. This review provides a summary of the updates and highlights the similarities and differences between the systems.

Diffuse large B‑cell lymphoma of the CNS

Open Access Diffuse Large B-Cell Lymphoma Case Study

A 68-year-old woman was admitted to the emergency department with headache, mental confusion, and a mild hemiparesis. Explore the imaging findings, differential diagnosis, and histopathological findings that revealed the patient’s diagnosis.

Targeting the PAM pathway in cancer

Open Access Targeted Therapy Review

The key clinical trial results for agents targeting the PI3K/AKT/mTOR signaling pathway in cancer are outlined and the major mechanisms of resistance to these inhibitors are discussed.

Atorvastatin reduces anthracycline-associated cardiac dysfunction

Lymphoma patients at high risk for anthracycline-associated cardiac dysfunction may benefit from the prophylactic use of atorvastatin.

Brentuximab vedotin for Hodgkin lymphoma with hepatic impairment

First-line treatment with single-agent brentuximab vedotin shows promise in two patients with Hodgkin lymphoma and severe hepatic impairment.

Myelodysplastic clones arising after CAR T-cell therapy

A case of myelodysplastic syndrome developing 21 months after CAR T-cell therapy as a potential long-term consequence of this new strategy.

Anthracyclines may increase heart failure risk among YA cancer survivors

Anthracycline exposure in young adults who previously received cancer treatment is associated with a significantly elevated risk for heart failure.

Pure red cell aplasia with underlying Waldenström macroglobulinemia

Open Access Checkpoint Inhibitors Case Study

Systematic investigation of anemia in a patient receiving immune checkpoint inhibitor treatment for metastatic castration-resistant prostate cancer revealed a diagnosis of secondary pure red cell aplasia with underlying Waldenström macroglobulinemia.

Real-world data add support for ICI use in people with HIV and cancer

25-05-2023 Checkpoint Inhibitors News

The use of immune checkpoint inhibitors is not associated with excess toxicity in people living with HIV and a concomitant diagnosis of cancer.

Successful treatment with cyclosporine of pure red cell aplasia induced by obinutuzumab bendamustine therapy

Anemia Case Study

Pure red cell aplasia is a rare side effect of bendamustine and should be considered if anemia progresses during treatment with regimens containing the drug.