A case series of three patients suggests that obinutuzumab-induced acute thrombocytopenia is a frequent, possibly non-relapsing, and unique adverse event that deserves more attention than it currently receives.
Richter’s transformation is a rare complication of chronic lymphocytic leukemia that is associated with poor outcomes. The evolving landscape of its treatment is discussed in this review.
PCNSL is a B-cell non-Hodgkin lymphoma in the brain, spinal cord, CSF, or eyes, without systemic manifestations. Though relapses are common, PCNSL is treatable in most cases, making timely diagnosis and treatment essential.
A wide range of complementary and integrative approaches are being studied in lymphoma and may prove beneficial for patients. But better patient–practitioner communication and systematic evaluation of potential safety issues are crucial.
Although cauda equina syndrome in the context of secondary CNS lymphoma is a rare occurrence, it should be considered in at-risk patients, especially those presenting with abnormal neurological findings.
Two new classification systems for T/NK-cell lymphomas and lymphoproliferative disorders were released recently. This review provides a summary of the updates and highlights the similarities and differences between the systems.
A 68-year-old woman was admitted to the emergency department with headache, mental confusion, and a mild hemiparesis. Explore the imaging findings, differential diagnosis, and histopathological findings that revealed the patient’s diagnosis.
The key clinical trial results for agents targeting the PI3K/AKT/mTOR signaling pathway in cancer are outlined and the major mechanisms of resistance to these inhibitors are discussed.
Systematic investigation of anemia in a patient receiving immune checkpoint inhibitor treatment for metastatic castration-resistant prostate cancer revealed a diagnosis of secondary pure red cell aplasia with underlying Waldenström macroglobulinemia.
Pure red cell aplasia is a rare side effect of bendamustine and should be considered if anemia progresses during treatment with regimens containing the drug.