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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 4/2016

01-08-2016 | Gastrointestinal Oncology

Impact of Sarcopenic Obesity on Surgical Site Infection after Laparoscopic Total Gastrectomy

Authors: Tatsuto Nishigori, MD, Shigeru Tsunoda, MD, PhD, Hiroshi Okabe, MD, PhD, Eiji Tanaka, MD, PhD, Shigeo Hisamori, MD, PhD, Hisahiro Hosogi, MD, PhD, Hisashi Shinohara, MD, PhD, Yoshiharu Sakai, MD, PhD

Published in: Annals of Surgical Oncology | Special Issue 4/2016

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Abstract

Background

The critical risk factors for surgical site infection (SSI) after laparoscopic total gastrectomy (LTG) remain unclear. We analyzed the association between body composition and SSI after LTG.

Methods

We performed a retrospective study of patients with gastric cancer who underwent LTG between March 2006 and October 2014 at Kyoto University Hospital, Japan. Visceral fat area and skeletal muscle mass were assessed from preoperative computed tomography scans to define sarcopenia and obesity. Patients were classified into one of four body composition categories according to the presence or absence of sarcopenia or obesity. The incidence of SSI was compared between the four body composition categories.

Results

Of the 157 eligible patients, 45 (24 %) fulfilled the criteria for sarcopenic obesity, 28 (18 %) for nonsarcopenic obesity, 52 (33 %) for sarcopenic nonobesity, and 32 (20 %) for nonsarcopenic nonobesity. Thirty-two patients developed SSI (overall incidence rate, 20 %). The incidence of SSI in each body composition category was 33, 25, 13, and 9 %, respectively (P = 0.03). Multivariate logistic regression analysis showed that only sarcopenic obesity was associated with an increased incidence of SSI (odds ratio 4.59, 95 % confidence interval 1.18–17.78, P = 0.028).

Conclusions

Sarcopenic obesity is an independent risk factor for the development of SSI after LTG.
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Metadata
Title
Impact of Sarcopenic Obesity on Surgical Site Infection after Laparoscopic Total Gastrectomy
Authors
Tatsuto Nishigori, MD
Shigeru Tsunoda, MD, PhD
Hiroshi Okabe, MD, PhD
Eiji Tanaka, MD, PhD
Shigeo Hisamori, MD, PhD
Hisahiro Hosogi, MD, PhD
Hisashi Shinohara, MD, PhD
Yoshiharu Sakai, MD, PhD
Publication date
01-08-2016
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 4/2016
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-016-5385-y

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