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Published in: BMC Infectious Diseases 1/2019

Open Access 01-12-2019 | Tuberculosis | Case report

Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome – a case report of a complicated scenario

Authors: Gopalan Narendran, Deivide Oliveira-de-Souza, Caian L. Vinhaes, Kevan Akrami, Kiyoshi F. Fukutani, Kesavamurthy Banu, Padmapriyadarsini Chandrasekaran, Narayanan Ravichandran, Irini Sereti, Soumya Swaminathan, Bruno B. Andrade

Published in: BMC Infectious Diseases | Issue 1/2019

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Abstract

Background

Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretroviral therapy commencement.

Case presentation

We present a rare case of a 51-year-old woman living with HIV who developed a series of TB-IRIS events occurring at multiple sites sequentially, highlighting the clinical complexity in diagnosis and management.

Conclusion

This case illustrates how complicated a clinical scenario of successive TB-IRIS episodes can be, in terms of clinical management.
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Metadata
Title
Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome – a case report of a complicated scenario
Authors
Gopalan Narendran
Deivide Oliveira-de-Souza
Caian L. Vinhaes
Kevan Akrami
Kiyoshi F. Fukutani
Kesavamurthy Banu
Padmapriyadarsini Chandrasekaran
Narayanan Ravichandran
Irini Sereti
Soumya Swaminathan
Bruno B. Andrade
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2019
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-019-4182-1

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