Skip to main content
Top
Published in: BMC Geriatrics 1/2016

Open Access 01-12-2016 | Debate

Sarcopenia in daily practice: assessment and management

Authors: Charlotte Beaudart, Eugène McCloskey, Olivier Bruyère, Matteo Cesari, Yves Rolland, René Rizzoli, Islène Araujo de Carvalho, Jotheeswaran Amuthavalli Thiyagarajan, Ivan Bautmans, Marie-Claude Bertière, Maria Luisa Brandi, Nasser M. Al-Daghri, Nansa Burlet, Etienne Cavalier, Francesca Cerreta, Antonio Cherubini, Roger Fielding, Evelien Gielen, Francesco Landi, Jean Petermans, Jean-Yves Reginster, Marjolein Visser, John Kanis, Cyrus Cooper

Published in: BMC Geriatrics | Issue 1/2016

Login to get access

Abstract

Background

Sarcopenia is increasingly recognized as a correlate of ageing and is associated with increased likelihood of adverse outcomes including falls, fractures, frailty and mortality. Several tools have been recommended to assess muscle mass, muscle strength and physical performance in clinical trials. Whilst these tools have proven to be accurate and reliable in investigational settings, many are not easily applied to daily practice.

Methods

This paper is based on literature reviews performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) working group on frailty and sarcopenia. Face-to-face meetings were afterwards organized for the whole group to make amendments and discuss further recommendations.

Results

This paper proposes some user-friendly and inexpensive methods that can be used to assess sarcopenia in real-life settings. Healthcare providers, particularly in primary care, should consider an assessment of sarcopenia in individuals at increased risk; suggested tools for assessing risk include the Red Flag Method, the SARC-F questionnaire, the SMI method or different prediction equations. Management of sarcopenia should primarily be patient centered and involve the combination of both resistance and endurance based activity programmes with or without dietary interventions. Development of a number of pharmacological interventions is also in progress.

Conclusions

Assessment of sarcopenia in individuals with risk factors, symptoms and/or conditions exposing them to the risk of disability will become particularly important in the near future.
Literature
1.
go back to reference Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr. 1997;127:990S–1S.PubMed Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr. 1997;127:990S–1S.PubMed
2.
go back to reference Muscaritoli M, et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) ‘cachexia-anorexia in chronic wasting diseases’ and ‘nutrition in geriatrics’. Clin Nutr. 2010;29:154–9.CrossRefPubMed Muscaritoli M, et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) ‘cachexia-anorexia in chronic wasting diseases’ and ‘nutrition in geriatrics’. Clin Nutr. 2010;29:154–9.CrossRefPubMed
3.
go back to reference Cruz-Jentoft AJ, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23.CrossRefPubMedPubMedCentral Cruz-Jentoft AJ, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–23.CrossRefPubMedPubMedCentral
4.
go back to reference Fielding RA, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12:249–56.CrossRefPubMed Fielding RA, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12:249–56.CrossRefPubMed
5.
7.
go back to reference Studenski SA, et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci. 2014;69:547–58.CrossRefPubMedPubMedCentral Studenski SA, et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci. 2014;69:547–58.CrossRefPubMedPubMedCentral
8.
go back to reference Baumgartner RN, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147:755–63.CrossRefPubMed Baumgartner RN, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147:755–63.CrossRefPubMed
9.
go back to reference Cooper C, et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int. 2012;23:1839–48.CrossRefPubMed Cooper C, et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int. 2012;23:1839–48.CrossRefPubMed
10.
go back to reference Chen L-K, et al. Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc. 2014;15:95–101.CrossRefPubMed Chen L-K, et al. Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc. 2014;15:95–101.CrossRefPubMed
11.
go back to reference Cruz-Jentoft AJ. et al. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing. 2014. doi:10.1093/ageing/afu115 Cruz-Jentoft AJ. et al. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing. 2014. doi:10.​1093/​ageing/​afu115
12.
go back to reference Bischoff-Ferrari HA, et al. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporos Int. 2015. doi:10.1007/s00198-015-3194-y. Bischoff-Ferrari HA, et al. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporos Int. 2015. doi:10.​1007/​s00198-015-3194-y.
13.
go back to reference Beaudart C, Rizzoli R, Bruyere O, Reginster JY, Biver E. Sarcopenia: Burden and challenges for Public Health. 2014. Archives of Public Health. Arch Public Heal. 2014;72:45.CrossRef Beaudart C, Rizzoli R, Bruyere O, Reginster JY, Biver E. Sarcopenia: Burden and challenges for Public Health. 2014. Archives of Public Health. Arch Public Heal. 2014;72:45.CrossRef
15.
go back to reference Lauretani F, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95:1851–60.CrossRefPubMed Lauretani F, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95:1851–60.CrossRefPubMed
17.
go back to reference Lang T, et al. Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos Int. 2010;21:543–59.CrossRefPubMed Lang T, et al. Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos Int. 2010;21:543–59.CrossRefPubMed
19.
go back to reference Landi F, et al. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clin Nutr. 2012;31:652–8.CrossRefPubMed Landi F, et al. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clin Nutr. 2012;31:652–8.CrossRefPubMed
20.
go back to reference Denison HJ, Cooper C, Sayer AA, Robinson SM. Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clin Interv Aging. 2015;10:859–69.PubMedPubMedCentral Denison HJ, Cooper C, Sayer AA, Robinson SM. Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clin Interv Aging. 2015;10:859–69.PubMedPubMedCentral
21.
go back to reference Molfino A, Gioia G, Rossi Fanelli F, Muscaritoli M. Beta-hydroxy-beta-methylbutyrate supplementation in health and disease: a systematic review of randomized trials. Amino Acids. 2013;45:1273–92.CrossRefPubMed Molfino A, Gioia G, Rossi Fanelli F, Muscaritoli M. Beta-hydroxy-beta-methylbutyrate supplementation in health and disease: a systematic review of randomized trials. Amino Acids. 2013;45:1273–92.CrossRefPubMed
22.
go back to reference Devries MC, Phillips SM. Creatine supplementation during resistance training in older adults-a meta-analysis. Med Sci Sports Exerc. 2014;46:1194–203.CrossRefPubMed Devries MC, Phillips SM. Creatine supplementation during resistance training in older adults-a meta-analysis. Med Sci Sports Exerc. 2014;46:1194–203.CrossRefPubMed
24.
go back to reference Mijnarends DM, et al. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013;14:170–8.CrossRefPubMed Mijnarends DM, et al. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013;14:170–8.CrossRefPubMed
25.
go back to reference Hiligsmann M, et al. A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum. 2014;44:271–82.CrossRefPubMed Hiligsmann M, et al. A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum. 2014;44:271–82.CrossRefPubMed
26.
go back to reference Rizzoli R, et al. The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 2014;79:122–32.CrossRefPubMed Rizzoli R, et al. The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 2014;79:122–32.CrossRefPubMed
27.
go back to reference Bruyère O, et al. An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: a report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum. 2014;44:253–63.CrossRefPubMed Bruyère O, et al. An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: a report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Semin Arthritis Rheum. 2014;44:253–63.CrossRefPubMed
28.
29.
go back to reference Arden N, et al. Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty. Drugs Aging. 2015;32:525–35.CrossRefPubMedPubMedCentral Arden N, et al. Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty. Drugs Aging. 2015;32:525–35.CrossRefPubMedPubMedCentral
31.
go back to reference Rizzoli R, et al. Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin. 2013;29:305–13.CrossRefPubMed Rizzoli R, et al. Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Curr Med Res Opin. 2013;29:305–13.CrossRefPubMed
33.
go back to reference Rizzoli R, et al. Guidance for the prevention of bone loss and fractures in postmenopausal women treated with aromatase inhibitors for breast cancer: an ESCEO position paper. Osteoporos Int. 2012;23:2567–76.CrossRefPubMed Rizzoli R, et al. Guidance for the prevention of bone loss and fractures in postmenopausal women treated with aromatase inhibitors for breast cancer: an ESCEO position paper. Osteoporos Int. 2012;23:2567–76.CrossRefPubMed
34.
go back to reference Reginster J-Y, et al. Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: expert consensus statement. Osteoarthritis Cartilage. 2015. doi:10.1016/j.joca.2015.07.001. Reginster J-Y, et al. Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: expert consensus statement. Osteoarthritis Cartilage. 2015. doi:10.​1016/​j.​joca.​2015.​07.​001.
35.
go back to reference Reginster J-Y, et al. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clin Exp Res. 2015;28:47–58.CrossRefPubMedPubMedCentral Reginster J-Y, et al. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clin Exp Res. 2015;28:47–58.CrossRefPubMedPubMedCentral
36.
go back to reference Hunter S, White M, Thompson M. Techniques to evaluate elderly human muscle function: a physiological basis. J Gerontol Biol Sci. 1998;53:2–4. Hunter S, White M, Thompson M. Techniques to evaluate elderly human muscle function: a physiological basis. J Gerontol Biol Sci. 1998;53:2–4.
37.
go back to reference Beaudart C, et al. Estimation of sarcopenia prevalence using various assessment tools. Exp Gerontol. 2014;61C:31–7. Beaudart C, et al. Estimation of sarcopenia prevalence using various assessment tools. Exp Gerontol. 2014;61C:31–7.
39.
go back to reference Mitsiopoulos N, et al. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol. 1998;85:115–22.PubMed Mitsiopoulos N, et al. Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol. 1998;85:115–22.PubMed
40.
go back to reference Levine JA, et al. Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry. J Appl Physiol. 2000;88:452–6.PubMed Levine JA, et al. Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry. J Appl Physiol. 2000;88:452–6.PubMed
41.
go back to reference Visser M, Fuerst T, Lang T, Salamone L, Harris TB. Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working Group. J Appl Physiol. 1999;87:1513–20.PubMed Visser M, Fuerst T, Lang T, Salamone L, Harris TB. Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working Group. J Appl Physiol. 1999;87:1513–20.PubMed
42.
go back to reference Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc. 2002;50:889–96.CrossRefPubMed Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc. 2002;50:889–96.CrossRefPubMed
43.
go back to reference Rush EC, Freitas I, Plank LD. Body size, body composition and fat distribution: comparative analysis of European, Maori, Pacific Island and Asian Indian adults. Br J Nutr. 2009;102:632–41.CrossRefPubMed Rush EC, Freitas I, Plank LD. Body size, body composition and fat distribution: comparative analysis of European, Maori, Pacific Island and Asian Indian adults. Br J Nutr. 2009;102:632–41.CrossRefPubMed
44.
go back to reference Bruyère O, et al. Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey. Eur Geriatr Med. 2016;7:243–6.CrossRef Bruyère O, et al. Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey. Eur Geriatr Med. 2016;7:243–6.CrossRef
45.
go back to reference Landi F, et al. Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Clin Nutr. 2010;29:441–7.CrossRefPubMed Landi F, et al. Midarm muscle circumference, physical performance and mortality: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Clin Nutr. 2010;29:441–7.CrossRefPubMed
46.
go back to reference Landi F, et al. Calf circumference, frailty and physical performance among older adults living in the community. Clin Nutr. 2014;33:539–44.CrossRefPubMed Landi F, et al. Calf circumference, frailty and physical performance among older adults living in the community. Clin Nutr. 2014;33:539–44.CrossRefPubMed
47.
go back to reference Rolland Y, et al. Sarcopenia, calf circumference, and physical function of elderly women: a cross-sectional study. J Am Geriatr Soc. 2003;51:1120–4.CrossRefPubMed Rolland Y, et al. Sarcopenia, calf circumference, and physical function of elderly women: a cross-sectional study. J Am Geriatr Soc. 2003;51:1120–4.CrossRefPubMed
48.
go back to reference Heymsfield SB, McManus C, Smith J, Stevens V, Nixon DW. Anthropometric measurement of muscle mass: revised equations for calculating bone-free arm muscle area. Am J Clin Nutr. 1982;36:680–90.PubMed Heymsfield SB, McManus C, Smith J, Stevens V, Nixon DW. Anthropometric measurement of muscle mass: revised equations for calculating bone-free arm muscle area. Am J Clin Nutr. 1982;36:680–90.PubMed
49.
go back to reference Kulkarni B, et al. Development and validation of anthropometric prediction equations for estimation of lean body mass and appendicular lean soft tissue in Indian men and women. J Appl Physiol. 2013;115:1156–62.CrossRefPubMedPubMedCentral Kulkarni B, et al. Development and validation of anthropometric prediction equations for estimation of lean body mass and appendicular lean soft tissue in Indian men and women. J Appl Physiol. 2013;115:1156–62.CrossRefPubMedPubMedCentral
50.
go back to reference Yu S, et al. An anthropometric prediction equation for appendicular skeletal muscle mass in combination with a measure of muscle function to screen for sarcopenia in primary and aged care. J Am Med Dir Assoc. 2015;16:25–30.CrossRefPubMed Yu S, et al. An anthropometric prediction equation for appendicular skeletal muscle mass in combination with a measure of muscle function to screen for sarcopenia in primary and aged care. J Am Med Dir Assoc. 2015;16:25–30.CrossRefPubMed
51.
go back to reference Villani AM, et al. Appendicular skeletal muscle in hospitalised hip-fracture patients: development and cross-validation of anthropometric prediction equations against dual-energy X-ray absorptiometry. Age Ageing. 2014;43:857–62.CrossRefPubMed Villani AM, et al. Appendicular skeletal muscle in hospitalised hip-fracture patients: development and cross-validation of anthropometric prediction equations against dual-energy X-ray absorptiometry. Age Ageing. 2014;43:857–62.CrossRefPubMed
52.
go back to reference Reiss J, et al. Case finding for sarcopenia in geriatric inpatients: performance of bioimpedance analysis in comparison to dual X-ray absorptiometry. BMC Geriatr. 2016;16:52.CrossRefPubMedPubMedCentral Reiss J, et al. Case finding for sarcopenia in geriatric inpatients: performance of bioimpedance analysis in comparison to dual X-ray absorptiometry. BMC Geriatr. 2016;16:52.CrossRefPubMedPubMedCentral
53.
go back to reference Kim M, Kim H. Accuracy of segmental multi-frequency bioelectrical impedance analysis for assessing whole-body and appendicular fat mass and lean soft tissue mass in frail women aged 75 years and older. Eur J Clin Nutr. 2013;67:395–400.CrossRefPubMed Kim M, Kim H. Accuracy of segmental multi-frequency bioelectrical impedance analysis for assessing whole-body and appendicular fat mass and lean soft tissue mass in frail women aged 75 years and older. Eur J Clin Nutr. 2013;67:395–400.CrossRefPubMed
54.
go back to reference Kim M, Shinkai S, Murayama H, Mori S. Comparison of segmental multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for the assessment of body composition in a community-dwelling older population. Geriatr Gerontol Int. 2015;15:1013–22.CrossRefPubMed Kim M, Shinkai S, Murayama H, Mori S. Comparison of segmental multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for the assessment of body composition in a community-dwelling older population. Geriatr Gerontol Int. 2015;15:1013–22.CrossRefPubMed
55.
go back to reference Buckinx F, et al. Concordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptiometry: a cross-sectional study. BMC Musculoskelet Disord. 2015;16:60.CrossRefPubMedPubMedCentral Buckinx F, et al. Concordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptiometry: a cross-sectional study. BMC Musculoskelet Disord. 2015;16:60.CrossRefPubMedPubMedCentral
56.
go back to reference Stevens PJ, et al. Is grip strength a good marker of physical performance among community-dwelling older people? J Nutr Heal Aging. 2012;16:769–74.CrossRef Stevens PJ, et al. Is grip strength a good marker of physical performance among community-dwelling older people? J Nutr Heal Aging. 2012;16:769–74.CrossRef
57.
go back to reference Bohannon RW, Magasi SR, Bubela DJ, Wang Y-C, Gershon RC. Grip and knee extension muscle strength reflect a common construct among adults. Muscle Nerve. 2012;46:555–8.CrossRefPubMedPubMedCentral Bohannon RW, Magasi SR, Bubela DJ, Wang Y-C, Gershon RC. Grip and knee extension muscle strength reflect a common construct among adults. Muscle Nerve. 2012;46:555–8.CrossRefPubMedPubMedCentral
58.
go back to reference Roberts HC, et al. A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing. 2011;40:423–9.CrossRefPubMed Roberts HC, et al. A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing. 2011;40:423–9.CrossRefPubMed
59.
go back to reference Bean JF, et al. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002;50:461–7.CrossRefPubMed Bean JF, et al. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002;50:461–7.CrossRefPubMed
61.
go back to reference Anjum SN, Choudary P, Dimri R, Ankarath S. Comparative evaluation of grip and pinch strength in an Asian and European population. Hand Ther. 2012;17:11–4.CrossRef Anjum SN, Choudary P, Dimri R, Ankarath S. Comparative evaluation of grip and pinch strength in an Asian and European population. Hand Ther. 2012;17:11–4.CrossRef
62.
go back to reference Brown M, Sinacore DR, Binder EF, Kohrt WM. Physical and performance measures for the identification of mild to moderate frailty. J Gerontol A Biol Sci Med Sci. 2000;55:M350–5.CrossRefPubMed Brown M, Sinacore DR, Binder EF, Kohrt WM. Physical and performance measures for the identification of mild to moderate frailty. J Gerontol A Biol Sci Med Sci. 2000;55:M350–5.CrossRefPubMed
63.
go back to reference Callahan D, Phillips E, Carabello R, Frontera WR, Fielding RA. Assessment of lower extremity muscle power in functionally-limited elders. Aging Clin Exp Res. 2007;19:194–9.CrossRefPubMed Callahan D, Phillips E, Carabello R, Frontera WR, Fielding RA. Assessment of lower extremity muscle power in functionally-limited elders. Aging Clin Exp Res. 2007;19:194–9.CrossRefPubMed
64.
go back to reference Jones CJ, Rikli RE, Beam WC. A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Q Exerc Sport. 1999;70:113–9.CrossRefPubMed Jones CJ, Rikli RE, Beam WC. A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Q Exerc Sport. 1999;70:113–9.CrossRefPubMed
65.
go back to reference Karpman C, Lebrasseur NK, Depew ZS, Novotny PJ, Benzo RP. Measuring gait speed in the out-patient clinic: methodology and feasibility. Respir Care. 2014;59:531–7.CrossRefPubMed Karpman C, Lebrasseur NK, Depew ZS, Novotny PJ, Benzo RP. Measuring gait speed in the out-patient clinic: methodology and feasibility. Respir Care. 2014;59:531–7.CrossRefPubMed
67.
go back to reference Bean JF, Kiely DK, LaRose S, Alian J, Frontera WR. Is Stair Climb Power a Clinically Relevant Measure of Leg Power Impairments in At-Risk Older Adults? Arch Phys Med Rehabil. 2007;88:604–9.CrossRefPubMed Bean JF, Kiely DK, LaRose S, Alian J, Frontera WR. Is Stair Climb Power a Clinically Relevant Measure of Leg Power Impairments in At-Risk Older Adults? Arch Phys Med Rehabil. 2007;88:604–9.CrossRefPubMed
68.
go back to reference Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev. 1996;54:S59–65.CrossRefPubMed Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev. 1996;54:S59–65.CrossRefPubMed
69.
go back to reference Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013;14:531–2.CrossRefPubMed Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013;14:531–2.CrossRefPubMed
70.
go back to reference Woo J, Leung J, Morley JE. Validating the SARC-F: a suitable community screening tool for sarcopenia? J Am Med Dir Assoc. 2014;15:630–4.CrossRefPubMed Woo J, Leung J, Morley JE. Validating the SARC-F: a suitable community screening tool for sarcopenia? J Am Med Dir Assoc. 2014;15:630–4.CrossRefPubMed
71.
go back to reference Goodman MJ, et al. Development of a practical screening tool to predict low muscle mass using NHANES 1999–2004. J Cachexia Sarcopenia Muscle. 2013;4:187–97.CrossRefPubMedPubMedCentral Goodman MJ, et al. Development of a practical screening tool to predict low muscle mass using NHANES 1999–2004. J Cachexia Sarcopenia Muscle. 2013;4:187–97.CrossRefPubMedPubMedCentral
73.
go back to reference Ishii S, et al. Development of a simple screening test for sarcopenia in older adults. Geriatr Gerontol Int. 2014;14 Suppl 1:93–101.CrossRefPubMed Ishii S, et al. Development of a simple screening test for sarcopenia in older adults. Geriatr Gerontol Int. 2014;14 Suppl 1:93–101.CrossRefPubMed
74.
go back to reference Sayer AA, et al. Type 2 Diabetes, Muscle Strength, and Impaired Physical Function: The tip of the iceberg? Diabetes Care. 2005;28:2541–2.CrossRefPubMed Sayer AA, et al. Type 2 Diabetes, Muscle Strength, and Impaired Physical Function: The tip of the iceberg? Diabetes Care. 2005;28:2541–2.CrossRefPubMed
76.
go back to reference Kalyani RR, Corriere M, Ferrucci L. Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. Lancet Diabetes Endocrinol. 2014;2:819–29.CrossRefPubMedPubMedCentral Kalyani RR, Corriere M, Ferrucci L. Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. Lancet Diabetes Endocrinol. 2014;2:819–29.CrossRefPubMedPubMedCentral
77.
go back to reference Peterson MD, Sen A, Gordon PM. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sport Exerc. 2011;43:249–58.CrossRef Peterson MD, Sen A, Gordon PM. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sport Exerc. 2011;43:249–58.CrossRef
78.
go back to reference Sahni S, Mangano KM, Hannan MT, Kiel DP, McLean RR. Higher Protein Intake Is Associated with Higher Lean Mass and Quadriceps Muscle Strength in Adult Men and Women. J Nutr. 2015;145:1569–75.CrossRefPubMedPubMedCentral Sahni S, Mangano KM, Hannan MT, Kiel DP, McLean RR. Higher Protein Intake Is Associated with Higher Lean Mass and Quadriceps Muscle Strength in Adult Men and Women. J Nutr. 2015;145:1569–75.CrossRefPubMedPubMedCentral
79.
go back to reference Genaro Pde S, Pinheiro Mde M, Szejnfeld VL, Martini LA. Dietary protein intake in elderly women: association with muscle and bone mass. Nutr Clin Pract. 2015;30:283–9. Genaro Pde S, Pinheiro Mde M, Szejnfeld VL, Martini LA. Dietary protein intake in elderly women: association with muscle and bone mass. Nutr Clin Pract. 2015;30:283–9.
80.
go back to reference Bauer J, et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc. 2013;14:542–59.CrossRefPubMed Bauer J, et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc. 2013;14:542–59.CrossRefPubMed
82.
go back to reference Gryson C, et al. Four-month course of soluble milk proteins interacts with exercise to improve muscle strength and delay fatigue in elderly participants. J Am Med Dir Assoc. 2014;15:958.e1–9.CrossRefPubMed Gryson C, et al. Four-month course of soluble milk proteins interacts with exercise to improve muscle strength and delay fatigue in elderly participants. J Am Med Dir Assoc. 2014;15:958.e1–9.CrossRefPubMed
83.
go back to reference Finger D, et al. Effects of protein supplementation in older adults undergoing resistance training: a systematic review and meta-analysis. Sports Med. 2015;45:245–55.CrossRefPubMed Finger D, et al. Effects of protein supplementation in older adults undergoing resistance training: a systematic review and meta-analysis. Sports Med. 2015;45:245–55.CrossRefPubMed
84.
go back to reference Beaudart C. et al. The effects of vitamin D on skeletal muscle strength, muscle mass and muscle power: a systematic review and meta-analysis of randomized controlled trials. J Clin Endocrinol Metab jc20141742 (2014). doi:10.1210/jc.2014-1742 Beaudart C. et al. The effects of vitamin D on skeletal muscle strength, muscle mass and muscle power: a systematic review and meta-analysis of randomized controlled trials. J Clin Endocrinol Metab jc20141742 (2014). doi:10.​1210/​jc.​2014-1742
Metadata
Title
Sarcopenia in daily practice: assessment and management
Authors
Charlotte Beaudart
Eugène McCloskey
Olivier Bruyère
Matteo Cesari
Yves Rolland
René Rizzoli
Islène Araujo de Carvalho
Jotheeswaran Amuthavalli Thiyagarajan
Ivan Bautmans
Marie-Claude Bertière
Maria Luisa Brandi
Nasser M. Al-Daghri
Nansa Burlet
Etienne Cavalier
Francesca Cerreta
Antonio Cherubini
Roger Fielding
Evelien Gielen
Francesco Landi
Jean Petermans
Jean-Yves Reginster
Marjolein Visser
John Kanis
Cyrus Cooper
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2016
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-016-0349-4

Other articles of this Issue 1/2016

BMC Geriatrics 1/2016 Go to the issue