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Published in: Nuclear Medicine and Molecular Imaging 3/2018

01-06-2018 | Review

Radiomics in Oncological PET/CT: Clinical Applications

Authors: Jeong Won Lee, Sang Mi Lee

Published in: Nuclear Medicine and Molecular Imaging | Issue 3/2018

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Abstract

18F–fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is widely used for staging, evaluating treatment response, and predicting prognosis in malignant diseases. FDG uptake and volumetric PET parameters such as metabolic tumor volume have been used and are still used as conventional PET parameters to assess biological characteristics of tumors. However, in recent years, additional features derived from PET images by computational processing have been found to reflect intratumoral heterogeneity, which is related to biological tumor features, and to provide additional predictive and prognostic information, which leads to the concept of radiomics. In this review, we focus on recent clinical studies of malignant diseases that investigated intratumoral heterogeneity on PET/CT, and we discuss its clinical role in various cancers.
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Metadata
Title
Radiomics in Oncological PET/CT: Clinical Applications
Authors
Jeong Won Lee
Sang Mi Lee
Publication date
01-06-2018
Publisher
Springer Berlin Heidelberg
Published in
Nuclear Medicine and Molecular Imaging / Issue 3/2018
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-017-0500-y

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