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Published in: Current Cardiovascular Imaging Reports 7/2018

01-07-2018 | Cardiac Magnetic Resonance (E Nagel and V Puntmann, Section Editors)

State of the Art in Cardiovascular T2 Mapping: on the Way to a Cardiac Biomarker?

Authors: Sebastian M. Haberkorn, Maximilian Spieker, Christoph Jacoby, Ulrich Flögel, Malte Kelm, Florian Bönner

Published in: Current Cardiovascular Imaging Reports | Issue 7/2018

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Abstract

Purpose of Review

Parametric mapping fosters the role of cardiovascular magnetic resonance in its unique capability to evaluate myocardial tissue without the use of contrast agents. While there is a large body of literature highlighting the role of T1 mapping, the role of T2 mapping is less clear. This review aims to address the latest evidences for added clinical value of T2 mapping.

Recent Findings

T2 mapping shows superior diagnostic accuracy in myocarditis, transplant rejection, and cardiac involvement in lupus erythematosus. Moreover, T2 values predict major adverse cardiovascular events in myocarditis and enable therapy monitoring in lupus erythematosus as well as after heart transplantation. In ischemic cardiomyopathy, T2 mapping discriminates acute from chronic injury and provides additional information for patient risk stratification.

Summary

T2 mapping provides a robust, quantifiable non-contrast-enhanced myocardial biomarker. However, there is no standardization in acquisition protocols, which formulates the future need for standardization ahead of multi-center trails.
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Metadata
Title
State of the Art in Cardiovascular T2 Mapping: on the Way to a Cardiac Biomarker?
Authors
Sebastian M. Haberkorn
Maximilian Spieker
Christoph Jacoby
Ulrich Flögel
Malte Kelm
Florian Bönner
Publication date
01-07-2018
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 7/2018
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-018-9455-3