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Neurocritical Care
Published in: Neurocritical Care 2/2019

01-10-2019 | Human Immunodeficiency Virus | A Day in the Life of a Neurocritical Care Trainee

A Case of HIV Seroconversion Presenting Similarly to Anti-N-methyl-d-aspartate Receptor Encephalitis

Authors: Heather VanDongen-Trimmer, Kumar Sannagowdara, Binod Balakrishnan, Raquel Farias-Moeller

Published in: Neurocritical Care | Issue 2/2019

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Excerpt

Continuous electroencephalogram (cEEG) monitoring is recommended in patients with acute supratentorial brain injury and altered mental status, such as patients with encephalitis. This practice may help facilitate prompt treatment of non-convulsive seizures and status epilepticus as well as assess the severity of encephalopathy [1]. As more critically ill patients with encephalopathy are being monitored with cEEG, experience is gained in recognizing EEG background patterns that can aid in prognostication, prediction of illness trajectory, and in a few occasions as biomarkers for specific disease processes [1]. …
Literature
1.
Herman ST, Abend NS, Bleck TP, et al. Consensus statement on continuous EEG in critically ill adults and children, part I: indications. J Clin Neurophysiol. 2015;32:87–95.CrossRef
2.
Vitaliani R, Mason W, Ances B, Zwerdling T, Jiang Z, Dalmau J. Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann Neurol. 2005;58:594–604.CrossRef
3.
Dalmau J, Tuzun E, Wu HY, et al. Paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007;61:25–36.CrossRef
4.
Gordon-Lipkin E, Yeshokumar AK, Saylor D, Arenivas A, Probasco JC. Comparative outcomes in children and adults with anti-N-methyl-d-aspartate (anti-NMDA) receptor encephalitis. J Child Neurol. 2017;32:930–5.CrossRef
5.
Guasp M, Dalmau J. Encephalitis associated with antibodies against the NMDA receptor. Med Clin (Barc). 2018;151:71–9.CrossRef
6.
Titulaer MJ, McCracken L, Gabilondo I, et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol. 2013;12:157–65.CrossRef
7.
Schmitt SE, Pargeon K, Frechette ES, Hirsch LJ, Dalmau J, Friedman D. Extreme delta brush: a unique EEG pattern in adults with anti-NMDA receptor encephalitis. Neurology. 2012;79:1094–100.CrossRef
8.
Wang J, Wang K, Wu D, Liang H, Zheng X, Luo B. Extreme delta brush guides to the diagnosis of anti-NMDAR encephalitis. J Neurol Sci. 2015;353:81–3.CrossRef
9.
Foff EP, Taplinger D, Suski J, Lopes MB, Quigg M. EEG findings may serve as a potential biomarker for anti-NMDA receptor encephalitis. Clin EEG Neurosci. 2017;48:48–53.CrossRef
10.
Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol. 2011;10:63–74.CrossRef
11.
Hinson HE, Takahashi C, Altowaijri G, Baguley IJ, Bourdette D. Anti-NMDA receptor encephalitis with paroxysmal sympathetic hyperactivity: an under-recognized association? Clin Auton Res. 2013;23:109–11.CrossRef
12.
Liu X, Yan B, Wang R, et al. Seizure outcomes in patients with anti-NMDAR encephalitis: a follow-up study. Epilepsia. 2017;58:2104–11.CrossRef
13.
Maneta E, Garcia G. Psychiatric manifestations of anti-NMDA receptor encephalitis: neurobiological underpinnings and differential diagnostic implications. Psychosomatics. 2014;55:37–44.CrossRef
14.
Mohammad SS, Dale RC. EEG background activity and extreme delta brush in children with anti-NMDAR encephalitis. Eur J Paediatr Neurol. 2018;22:207–8.CrossRef
15.
Castellano J, Glover R, Robinson J. Extreme delta brush in NMDA receptor encephalitis. Neurohospitalist. 2017;7:NP3–4.CrossRef
16.
Armangue T, Titulaer MJ, Malaga I, et al. Pediatric anti-N-methyl-d-aspartate receptor encephalitis-clinical analysis and novel findings in a series of 20 patients. J Pediatr. 2013;162(850–6):e2.
17.
Yildirim M, Konuskan B, Yalnizoglu D, Topaloglu H, Erol I, Anlar B. Electroencephalographic findings in anti-N-methyl-d-aspartate receptor encephalitis in children: a series of 12 patients. Epilepsy Behav. 2018;78:118–23.CrossRef
18.
Zhang Y, Liu G, Jiang MD, Li LP, Su YY. Analysis of electroencephalogram characteristics of anti-NMDA receptor encephalitis patients in China. Clin Neurophysiol. 2017;128:1227–33.CrossRef
19.
Casciato S, Gambardella S, Mascia A, et al. Severe and rapidly-progressive Lafora disease associated with NHLRC1 mutation: a case report. Int J Neurosci. 2017;127:1150–3.CrossRef
20.
Theroux LM, Goodkin HP, Heinan KC, Quigg M, Brenton JN. Extreme delta brush and distinctive imaging in a pediatric patient with autoimmune GFAP astrocytopathy. Mult Scler Relat Disord. 2018;26:121–3.CrossRef
21.
Schmidt LS, Kjaer TW, Schmiegelow K, Born AP. EEG with extreme delta brush in young female with methotrexate neurotoxicity supports NMDA receptor involvement. Eur J Paediatr Neurol. 2017;21:795–7.CrossRef
22.
Farias-Moeller R, Bartolini L, Staso K, Schreiber JM, Carpenter JL. Early ictal and interictal patterns in FIRES: the sparks before the blaze. Epilepsia. 2017;58:1340–8.CrossRef
23.
Baykan B, Gungor Tuncer O, Vanli-Yavuz EN, et al. Delta brush pattern is not unique to NMDAR encephalitis: evaluation of two independent long-term EEG cohorts. Clin EEG Neurosci. 2018;49:278–84.CrossRef
24.
Graus F, Titulaer MJ, Balu R, et al. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016;15:391–404.CrossRef
25.
Kahn JO, Walker BD. Acute human immunodeficiency virus type 1 infection. N Engl J Med. 1998;339:33–9.CrossRef
26.
Hogan C, Wilkins E. Neurological complications in HIV. Clin Med (Lond). 2011;11:571–5.CrossRef
27.
Zhang J, Liu J, Katafiasz B, Fox H, Xiong H. HIV-1 gp120-induced axonal injury detected by accumulation of beta-amyloid precursor protein in adult rat corpus callosum. J Neuroimmune Pharmacol. 2011;6:650–7.CrossRef
28.
Hoefer MM, Sanchez AB, Maung R, et al. Combination of methamphetamine and HIV-1 gp120 causes distinct long-term alterations of behavior, gene expression, and injury in the central nervous system. Exp Neurol. 2015;263:221–34.CrossRef
29.
Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature. 2001;410:988–94.CrossRef
30.
Zhou Y, Liu J, Xiong H. HIV-1 glycoprotein 120 enhancement of N-methyl-d-aspartate NMDA receptor-mediated excitatory postsynaptic currents: implications for HIV-1-associated neural injury. J Neuroimmune Pharmacol. 2017;12:314–26.CrossRef
31.
O’Donnell LA, Agrawal A, Jordan-Sciutto KL, Dichter MA, Lynch DR, Kolson DL. Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes. J Neurosci. 2006;26:981–90.CrossRef
Metadata
Title
A Case of HIV Seroconversion Presenting Similarly to Anti-N-methyl-d-aspartate Receptor Encephalitis
Authors
Heather VanDongen-Trimmer
Kumar Sannagowdara
Binod Balakrishnan
Raquel Farias-Moeller
Publication date
01-10-2019
Publisher
Springer US
Published in
Neurocritical Care / Issue 2/2019
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-019-00805-5

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