Skip to main content
Top
Published in: Obesity Surgery 4/2020

01-04-2020 | Original Contributions

Long-Term Outcomes After One-Anastomosis Gastric Bypass (OAGB) in Morbidly Obese Patients

Authors: Maud Neuberg, Marie-Cécile Blanchet, Benoit Gignoux, Vincent Frering

Published in: Obesity Surgery | Issue 4/2020

Login to get access

Abstract

Background

One-anastomosis gastric bypass (OAGB) has gradually gained in popularity. Evidence of the validity of the technique and the quality of life in the longer term is scarce. The aim of this study was to retrospectively evaluate the longitudinal (≥ 5 years) safety, weight-loss efficacy, comorbid disease improvement, and quality of life of patients following OAGB.

Methods

Data from patients who underwent OAGB from January 2009 to December 2011 were retrospectively reviewed. Preoperative clinical characteristics and data through 8 years were analyzed.

Results

A total of 163 patients completed 5 to 8 years of follow-up with a mean age of 41 ± 11.4 years (22–65). Ninety-four patients (57.6%) had undergone prior bariatric surgery (gastric band). Mean body mass index (BMI, kg/m2) at the time of OAGB was 41.2 ± 6.5 (range 30.1–50.6). Twenty-one patients (13.0%) suffered from type 2 diabetes mellitus (T2DM), 59 (36.2%) hypertension, 31 osteoarthritis (19.0%), and 24 had obstructive sleep apnea (14.7%). At 5, 6, 7, and 8 years of follow-up, respective mean BMI reduction was 12.6 (n = 163), 11.8 (n = 100), 10.7 (n = 82), and 8.8 (n = 40). Respective mean excess weight loss was 81.8 ± 23.6%, 75.9 ± 20.8%, 69.1 ± 20.4%, and 62.3 ± 23.4%. All obesity-related comorbidities decreased significantly at follow-up time points. Five patients (3%) underwent laparoscopic reoperation within 90 days after surgery. Incidence of recurrent reflux was 14.0%. At a mean follow-up of 92 months (76–111), improved or greatly improved quality of life was reported by 86.0% of patients.

Conclusion

OAGB provided very good weight loss, comorbidity improvement, and quality of life at follow-up of ≥ 5 years.
Literature
1.
go back to reference Rutledge R. The mini-gastric bypass: experience with the first 1274 cases. Obes Surg. 2001;11(3):276–80.CrossRef Rutledge R. The mini-gastric bypass: experience with the first 1274 cases. Obes Surg. 2001;11(3):276–80.CrossRef
2.
go back to reference Parmar CD, Mahawar KK. One-anastomosis (mini) gastric bypass is now an established bariatric procedure: a systematic review of 12,807 patients. Obes Surg. 2018;28(9):2956–67.CrossRef Parmar CD, Mahawar KK. One-anastomosis (mini) gastric bypass is now an established bariatric procedure: a systematic review of 12,807 patients. Obes Surg. 2018;28(9):2956–67.CrossRef
3.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28(12):3783–94.CrossRef Angrisani L, Santonicola A, Iovino P, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28(12):3783–94.CrossRef
4.
go back to reference Georgiadou D, Sergentanis TN, Nixon A, et al. Efficacy and safety of laparoscopic mini gastric bypass: a systematic review. Surg Obes Relat Dis. 2014;10:984–91.CrossRef Georgiadou D, Sergentanis TN, Nixon A, et al. Efficacy and safety of laparoscopic mini gastric bypass: a systematic review. Surg Obes Relat Dis. 2014;10:984–91.CrossRef
5.
go back to reference De Luca M, Tie T, Ooi G, et al. Mini gastric bypass–one anastomosis gastric bypass (MGB-OAGB)–IFSO position statement. Obes Surg. 2018;28(5):1188–206.CrossRef De Luca M, Tie T, Ooi G, et al. Mini gastric bypass–one anastomosis gastric bypass (MGB-OAGB)–IFSO position statement. Obes Surg. 2018;28(5):1188–206.CrossRef
6.
go back to reference Mahawar KK, Borg C-M, Kular KS, et al. Understanding objections to one anastomosis (mini) gastric bypass: a survey of 417 surgeons not performing this procedure. Obes Surg. 2017;27(9):2222–8.CrossRef Mahawar KK, Borg C-M, Kular KS, et al. Understanding objections to one anastomosis (mini) gastric bypass: a survey of 417 surgeons not performing this procedure. Obes Surg. 2017;27(9):2222–8.CrossRef
7.
go back to reference Guirat A, Addossari HM. One anastomosis gastric bypass and risk of cancer. Obes Surg. 2018;28(5):1441–4.CrossRef Guirat A, Addossari HM. One anastomosis gastric bypass and risk of cancer. Obes Surg. 2018;28(5):1441–4.CrossRef
9.
go back to reference Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017;27(9):2279–89.CrossRef Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017;27(9):2279–89.CrossRef
10.
go back to reference Fried M, Hainer V, Basdevant A, et al. Inter-disciplinary European guidelines on surgery of severe obesity. Int J Obes. 2007;31(4):569–77.CrossRef Fried M, Hainer V, Basdevant A, et al. Inter-disciplinary European guidelines on surgery of severe obesity. Int J Obes. 2007;31(4):569–77.CrossRef
11.
go back to reference NIH Consensus Development Conference Statement: gastrointestinal surgery for severe obesity. Obes Surg 1991;1:243-256. NIH Consensus Development Conference Statement: gastrointestinal surgery for severe obesity. Obes Surg 1991;1:243-256.
12.
go back to reference Moorehead MK, Ardelt-Gattinger E, Lechner H, et al. The validation of the Moorehead-Ardelt quality of life questionnaire II. Obes Surg. 2003;13(5):684–92.CrossRef Moorehead MK, Ardelt-Gattinger E, Lechner H, et al. The validation of the Moorehead-Ardelt quality of life questionnaire II. Obes Surg. 2003;13(5):684–92.CrossRef
13.
go back to reference Felsenreich DM, Ladinig LM, Beckerhinn P, et al. Update: 10 years of sleeve gastrectomy—the first 103 patients. Obes Surg. 2018;28(11):3586–94.CrossRef Felsenreich DM, Ladinig LM, Beckerhinn P, et al. Update: 10 years of sleeve gastrectomy—the first 103 patients. Obes Surg. 2018;28(11):3586–94.CrossRef
14.
go back to reference Singh T, Sanaka MR, Thota PN. Endoscopic therapy for Barrett’s esophagus and early esophageal cancer: where do we go from here? World J Gastrointest Endosc. 2018;10(9):165–74.CrossRef Singh T, Sanaka MR, Thota PN. Endoscopic therapy for Barrett’s esophagus and early esophageal cancer: where do we go from here? World J Gastrointest Endosc. 2018;10(9):165–74.CrossRef
15.
go back to reference Oor JE, Roks DJ, Ünlü C, et al. Laparoscopic sleeve gastrectomy and gastroesophageal reflux disease: a systematic review and meta-analysis. Am J Surg. 2016;211(1):250–67.CrossRef Oor JE, Roks DJ, Ünlü C, et al. Laparoscopic sleeve gastrectomy and gastroesophageal reflux disease: a systematic review and meta-analysis. Am J Surg. 2016;211(1):250–67.CrossRef
16.
go back to reference Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15(9):1304–8.CrossRef Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15(9):1304–8.CrossRef
17.
go back to reference Lee WJ, Yu PJ, Wang W, et al. Laparoscopic Roux-en-Y versus mini-gastric bypass for the treatment of morbid obesity: a prospective randomized controlled clinical trial. Ann Surg. 2005;242(1):20–8.CrossRef Lee WJ, Yu PJ, Wang W, et al. Laparoscopic Roux-en-Y versus mini-gastric bypass for the treatment of morbid obesity: a prospective randomized controlled clinical trial. Ann Surg. 2005;242(1):20–8.CrossRef
18.
go back to reference Lee WJ, Lin YH. Single-anastomosis gastric bypass (SAGB): appraisal of clinical evidence. Obes Surg. 2014;10:1749–56.CrossRef Lee WJ, Lin YH. Single-anastomosis gastric bypass (SAGB): appraisal of clinical evidence. Obes Surg. 2014;10:1749–56.CrossRef
19.
go back to reference Parmar CD, Bryant C, Luque-DeLeon E, et al. One anastomosis gastric bypass in morbidly obese patients with BMI ≥ 50 kg/m2: a systematic review comparing it with Roux-en-Y gastric bypass and sleeve gastrectomy. Obes Surg 2019 Sep;29(9):3039-3046. Parmar CD, Bryant C, Luque-DeLeon E, et al. One anastomosis gastric bypass in morbidly obese patients with BMI ≥ 50 kg/m2: a systematic review comparing it with Roux-en-Y gastric bypass and sleeve gastrectomy. Obes Surg 2019 Sep;29(9):3039-3046.
Metadata
Title
Long-Term Outcomes After One-Anastomosis Gastric Bypass (OAGB) in Morbidly Obese Patients
Authors
Maud Neuberg
Marie-Cécile Blanchet
Benoit Gignoux
Vincent Frering
Publication date
01-04-2020
Publisher
Springer US
Published in
Obesity Surgery / Issue 4/2020
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-019-04287-4

Other articles of this Issue 4/2020

Obesity Surgery 4/2020 Go to the issue