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Published in: The European Journal of Health Economics 1/2019

Open Access 01-06-2019 | Original Paper

Cost-of-illness studies in nine Central and Eastern European countries

Authors: Valentin Brodszky, Zsuzsanna Beretzky, Petra Baji, Fanni Rencz, Márta Péntek, Alexandru Rotar, Konstantin Tachkov, Susanne Mayer, Judit Simon, Maciej Niewada, Rok Hren, László Gulácsi

Published in: The European Journal of Health Economics | Special Issue 1/2019

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Abstract

Background

To date, a multi-country review evaluating the cost-of-illness (COI) studies from the Central and Eastern European (CEE) region has not yet been published. Our main objective was to provide a general description about published COI studies from CEE.

Methods

A systematic search was performed between 1 January 2006 and 1 June 2017 in Medline, EMBASE, The Cochrane Library, CINAHL, and Web of Science to identify all relevant COI studies from nine CEE countries. COI studies reporting costs without any restrictions by age, co-morbidities, or treatment were included. Methodology, publication standards, and cost results were analysed.

Results

We identified 58 studies providing 83 country-specific COI results: Austria (n = 9), Bulgaria (n = 16), Croatia (n = 3), the Czech Republic (n = 10), Hungary (n = 24), Poland (n = 11), Romania (n = 3), Slovakia (n = 3), and Slovenia (n = 4). Endocrine, nutritional, and metabolic diseases (18%), neoplasms (12%), infections (11%), and neurological disorders (11%) were the most frequently studied clinical areas, and multiple sclerosis was the most commonly studied disease. Overall, 57 (98%) of the studies explicitly stated the source of resource use data, 45 (78%) the study perspective, 34 (64%) the costing method, and 24 (58%) reported at least one unit costs. Regardless of methodological differences, a positive relationship was observed between costs of diseases and countries’ per capita GDP.

Conclusions

Cost-of-illness studies varied considerably in terms of methodology, publication practice, and clinical areas. Due to these heterogeneities, transferability of the COI results is limited across Central and Eastern European countries.
Appendix
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Metadata
Title
Cost-of-illness studies in nine Central and Eastern European countries
Authors
Valentin Brodszky
Zsuzsanna Beretzky
Petra Baji
Fanni Rencz
Márta Péntek
Alexandru Rotar
Konstantin Tachkov
Susanne Mayer
Judit Simon
Maciej Niewada
Rok Hren
László Gulácsi
Publication date
01-06-2019
Publisher
Springer Berlin Heidelberg
Published in
The European Journal of Health Economics / Issue Special Issue 1/2019
Print ISSN: 1618-7598
Electronic ISSN: 1618-7601
DOI
https://doi.org/10.1007/s10198-019-01066-x

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