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01-09-2016 | Review

New insights into basophil heterogeneity

Authors: Landon K. Oetjen, Mario Noti, Brian S. Kim

Published in: Seminars in Immunopathology | Issue 5/2016

Abstract

Basophils have become increasingly recognized as important innate immune cells that mediate antihelminth immunity and barrier inflammation. Recent discoveries have uncovered previously unrecognized heterogeneity in basophil populations. However, how diversity in basophil regulation and function impacts human disease remains poorly defined. The goal of the present review is to highlight how new insights into basophil heterogeneity can help us to better understand disease pathogenesis and inform the development of new therapeutics.

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Title: New insights into basophil heterogeneity
Authors: Landon K. Oetjen
Mario Noti
Brian S. Kim
Publication date: 01-09-2016
Publisher: Springer Berlin Heidelberg
Published in: Seminars in Immunopathology / Issue 5/2016
Print ISSN: 1863-2297
Electronic ISSN: 1863-2300
DOI: https://doi.org/10.1007/s00281-016-0567-z

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