Skip to main content
Top
Published in: Intensive Care Medicine 12/2017

Open Access 01-12-2017 | Conference Reports and Expert Panel

Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC)

Authors: Martin C. J. Kneyber, Daniele de Luca, Edoardo Calderini, Pierre-Henri Jarreau, Etienne Javouhey, Jesus Lopez-Herce, Jürg Hammer, Duncan Macrae, Dick G. Markhorst, Alberto Medina, Marti Pons-Odena, Fabrizio Racca, Gerhard Wolf, Paolo Biban, Joe Brierley, Peter C. Rimensberger, on behalf of the section Respiratory Failure of the European Society for Paediatric and Neonatal Intensive Care

Published in: Intensive Care Medicine | Issue 12/2017

Login to get access

Abstract

Purpose

Much of the common practice in paediatric mechanical ventilation is based on personal experiences and what paediatric critical care practitioners have adopted from adult and neonatal experience. This presents a barrier to planning and interpretation of clinical trials on the use of specific and targeted interventions. We aim to establish a European consensus guideline on mechanical ventilation of critically children.

Methods

The European Society for Paediatric and Neonatal Intensive Care initiated a consensus conference of international European experts in paediatric mechanical ventilation to provide recommendations using the Research and Development/University of California, Los Angeles, appropriateness method. An electronic literature search in PubMed and EMBASE was performed using a combination of medical subject heading terms and text words related to mechanical ventilation and disease-specific terms.

Results

The Paediatric Mechanical Ventilation Consensus Conference (PEMVECC) consisted of a panel of 15 experts who developed and voted on 152 recommendations related to the following topics: (1) general recommendations, (2) monitoring, (3) targets of oxygenation and ventilation, (4) supportive measures, (5) weaning and extubation readiness, (6) normal lungs, (7) obstructive diseases, (8) restrictive diseases, (9) mixed diseases, (10) chronically ventilated patients, (11) cardiac patients and (12) lung hypoplasia syndromes. There were 142 (93.4%) recommendations with “strong agreement”. The final iteration of the recommendations had none with equipoise or disagreement.

Conclusions

These recommendations should help to harmonise the approach to paediatric mechanical ventilation and can be proposed as a standard-of-care applicable in daily clinical practice and clinical research.
Appendix
Available only for authorised users
Literature
1.
go back to reference Santschi M, Jouvet P, Leclerc F, Gauvin F, Newth CJ, Carroll CL, Flori H, Tasker RC, Rimensberger PC, Randolph AG, Investigators P, Pediatric Acute Lung I, Sepsis Investigators N, European Society of P, Neonatal Intensive C (2010) Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. Pediatr Crit Care Med 11:681–689PubMedCrossRef Santschi M, Jouvet P, Leclerc F, Gauvin F, Newth CJ, Carroll CL, Flori H, Tasker RC, Rimensberger PC, Randolph AG, Investigators P, Pediatric Acute Lung I, Sepsis Investigators N, European Society of P, Neonatal Intensive C (2010) Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. Pediatr Crit Care Med 11:681–689PubMedCrossRef
2.
go back to reference Duyndam A, Ista E, Houmes RJ, van Driel B, Reiss I, Tibboel D (2011) Invasive ventilation modes in children: a systematic review and meta-analysis. Crit Care 15:R24PubMedPubMedCentralCrossRef Duyndam A, Ista E, Houmes RJ, van Driel B, Reiss I, Tibboel D (2011) Invasive ventilation modes in children: a systematic review and meta-analysis. Crit Care 15:R24PubMedPubMedCentralCrossRef
3.
go back to reference Chatburn RL, El-Khatib M, Mireles-Cabodevila E (2014) A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care 59:1747–1763PubMedCrossRef Chatburn RL, El-Khatib M, Mireles-Cabodevila E (2014) A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care 59:1747–1763PubMedCrossRef
4.
go back to reference Chatburn RL (2007) Classification of ventilator modes: update and proposal for implementation. Respir Care 52:301–323PubMed Chatburn RL (2007) Classification of ventilator modes: update and proposal for implementation. Respir Care 52:301–323PubMed
5.
go back to reference Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LaCalle JR, Lazaro P, van het Loo M, McDonell J, Vader JP, Kahan JP (2001) The RAND/UCLA appropriateness method user’s manual. RAND, Santa Monica Fitch K, Bernstein SJ, Aguilar MD, Burnand B, LaCalle JR, Lazaro P, van het Loo M, McDonell J, Vader JP, Kahan JP (2001) The RAND/UCLA appropriateness method user’s manual. RAND, Santa Monica
6.
go back to reference Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O’Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer T, Varonen H, Vist GE, Williams JW Jr, Zaza S, Group GW (2004) Grading quality of evidence and strength of recommendations. BMJ 328:1490PubMedCrossRef Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O’Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer T, Varonen H, Vist GE, Williams JW Jr, Zaza S, Group GW (2004) Grading quality of evidence and strength of recommendations. BMJ 328:1490PubMedCrossRef
7.
go back to reference Schwabbauer N, Berg B, Blumenstock G, Haap M, Hetzel J, Riessen R (2014) Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol 14:66PubMedPubMedCentralCrossRef Schwabbauer N, Berg B, Blumenstock G, Haap M, Hetzel J, Riessen R (2014) Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol 14:66PubMedPubMedCentralCrossRef
8.
go back to reference Pham TM, O’Malley L, Mayfield S, Martin S, Schibler A (2015) The effect of high flow nasal cannula therapy on the work of breathing in infants with bronchiolitis. Pediatr Pulmonol 50:713–720PubMedCrossRef Pham TM, O’Malley L, Mayfield S, Martin S, Schibler A (2015) The effect of high flow nasal cannula therapy on the work of breathing in infants with bronchiolitis. Pediatr Pulmonol 50:713–720PubMedCrossRef
9.
go back to reference Hough JL, Pham TM, Schibler A (2014) Physiologic effect of high-flow nasal cannula in infants with bronchiolitis. Pediatr Crit Care Med 15:e214–e219PubMedCrossRef Hough JL, Pham TM, Schibler A (2014) Physiologic effect of high-flow nasal cannula in infants with bronchiolitis. Pediatr Crit Care Med 15:e214–e219PubMedCrossRef
10.
go back to reference Mayfield S, Bogossian F, O’Malley L, Schibler A (2014) High-flow nasal cannula oxygen therapy for infants with bronchiolitis: pilot study. J Paediatr Child Health 50:373–378PubMedCrossRef Mayfield S, Bogossian F, O’Malley L, Schibler A (2014) High-flow nasal cannula oxygen therapy for infants with bronchiolitis: pilot study. J Paediatr Child Health 50:373–378PubMedCrossRef
11.
go back to reference Mayfield S, Jauncey-Cooke J, Hough JL, Schibler A, Gibbons K, Bogossian F (2014) High-flow nasal cannula therapy for respiratory support in children. Cochrane Database Syst Rev: CD009850 Mayfield S, Jauncey-Cooke J, Hough JL, Schibler A, Gibbons K, Bogossian F (2014) High-flow nasal cannula therapy for respiratory support in children. Cochrane Database Syst Rev: CD009850
12.
go back to reference Milesi C, Baleine J, Matecki S, Durand S, Combes C, Novais AR, Cambonie G (2013) Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Intensive Care Med 39:1088–1094PubMedCrossRef Milesi C, Baleine J, Matecki S, Durand S, Combes C, Novais AR, Cambonie G (2013) Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Intensive Care Med 39:1088–1094PubMedCrossRef
13.
go back to reference Rubin S, Ghuman A, Deakers T, Khemani R, Ross P, Newth CJ (2014) Effort of breathing in children receiving high-flow nasal cannula. Pediatr Crit Care Med 15:1–6PubMedCrossRef Rubin S, Ghuman A, Deakers T, Khemani R, Ross P, Newth CJ (2014) Effort of breathing in children receiving high-flow nasal cannula. Pediatr Crit Care Med 15:1–6PubMedCrossRef
14.
go back to reference Chisti MJ, Salam MA, Smith JH, Ahmed T, Pietroni MA, Shahunja KM, Shahid AS, Faruque AS, Ashraf H, Bardhan PK, Sharifuzzaman, Graham SM, Duke T (2015) Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial. Lancet 386:1057–1065PubMedCrossRef Chisti MJ, Salam MA, Smith JH, Ahmed T, Pietroni MA, Shahunja KM, Shahid AS, Faruque AS, Ashraf H, Bardhan PK, Sharifuzzaman, Graham SM, Duke T (2015) Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial. Lancet 386:1057–1065PubMedCrossRef
15.
go back to reference Kelly GS, Simon HK, Sturm JJ (2013) High-flow nasal cannula use in children with respiratory distress in the emergency department: predicting the need for subsequent intubation. Pediatr Emerg Care 29:888–892PubMedCrossRef Kelly GS, Simon HK, Sturm JJ (2013) High-flow nasal cannula use in children with respiratory distress in the emergency department: predicting the need for subsequent intubation. Pediatr Emerg Care 29:888–892PubMedCrossRef
16.
go back to reference Kneyber MC (2013) Question 1: Is there a role for high-flow nasal cannula oxygen therapy to prevent endotracheal intubation in children with viral bronchiolitis? Arch Dis Child 98:1018–1020PubMedCrossRef Kneyber MC (2013) Question 1: Is there a role for high-flow nasal cannula oxygen therapy to prevent endotracheal intubation in children with viral bronchiolitis? Arch Dis Child 98:1018–1020PubMedCrossRef
17.
go back to reference McKiernan C, Chua LC, Visintainer PF, Allen H (2010) High flow nasal cannulae therapy in infants with bronchiolitis. J Pediatr 156:634–638PubMedCrossRef McKiernan C, Chua LC, Visintainer PF, Allen H (2010) High flow nasal cannulae therapy in infants with bronchiolitis. J Pediatr 156:634–638PubMedCrossRef
18.
go back to reference Modesto IAV, Khemani RG, Medina A, Del Villar Guerra P, Molina Cambra A (2017) Bayes to the rescue: continuous positive airway pressure has less mortality than high-flow oxygen. Pediatr Crit Care Med 18:e92–e99CrossRef Modesto IAV, Khemani RG, Medina A, Del Villar Guerra P, Molina Cambra A (2017) Bayes to the rescue: continuous positive airway pressure has less mortality than high-flow oxygen. Pediatr Crit Care Med 18:e92–e99CrossRef
19.
go back to reference Riese J, Fierce J, Riese A, Alverson BK (2015) Effect of a hospital-wide high-flow nasal cannula protocol on clinical outcomes and resource utilization of bronchiolitis patients admitted to the PICU. Hosp Pediatr 5:613–618PubMedCrossRef Riese J, Fierce J, Riese A, Alverson BK (2015) Effect of a hospital-wide high-flow nasal cannula protocol on clinical outcomes and resource utilization of bronchiolitis patients admitted to the PICU. Hosp Pediatr 5:613–618PubMedCrossRef
20.
go back to reference Schibler A, Pham TM, Dunster KR, Foster K, Barlow A, Gibbons K, Hough JL (2011) Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Med 37:847–852PubMedCrossRef Schibler A, Pham TM, Dunster KR, Foster K, Barlow A, Gibbons K, Hough JL (2011) Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Med 37:847–852PubMedCrossRef
21.
go back to reference Wing R, James C, Maranda LS, Armsby CC (2012) Use of high-flow nasal cannula support in the emergency department reduces the need for intubation in pediatric acute respiratory insufficiency. Pediatr Emerg Care 28:1117–1123PubMedCrossRef Wing R, James C, Maranda LS, Armsby CC (2012) Use of high-flow nasal cannula support in the emergency department reduces the need for intubation in pediatric acute respiratory insufficiency. Pediatr Emerg Care 28:1117–1123PubMedCrossRef
22.
go back to reference Borckink I, Essouri S, Laurent M, Albers MJ, Burgerhof JG, Tissieres P, Kneyber MC (2014) Infants with severe respiratory syncytial virus needed less ventilator time with nasal continuous airways pressure then invasive mechanical ventilation. Acta Paediatr 103:81–85PubMedCrossRef Borckink I, Essouri S, Laurent M, Albers MJ, Burgerhof JG, Tissieres P, Kneyber MC (2014) Infants with severe respiratory syncytial virus needed less ventilator time with nasal continuous airways pressure then invasive mechanical ventilation. Acta Paediatr 103:81–85PubMedCrossRef
23.
go back to reference Cambonie G, Milesi C, Jaber S, Amsallem F, Barbotte E, Picaud JC, Matecki S (2008) Nasal continuous positive airway pressure decreases respiratory muscles overload in young infants with severe acute viral bronchiolitis. Intensive Care Med 34:1865–1872PubMedCrossRef Cambonie G, Milesi C, Jaber S, Amsallem F, Barbotte E, Picaud JC, Matecki S (2008) Nasal continuous positive airway pressure decreases respiratory muscles overload in young infants with severe acute viral bronchiolitis. Intensive Care Med 34:1865–1872PubMedCrossRef
24.
go back to reference Donlan M, Fontela PS, Puligandla PS (2011) Use of continuous positive airway pressure (CPAP) in acute viral bronchiolitis: a systematic review. Pediatr Pulmonol 46:736–746PubMedCrossRef Donlan M, Fontela PS, Puligandla PS (2011) Use of continuous positive airway pressure (CPAP) in acute viral bronchiolitis: a systematic review. Pediatr Pulmonol 46:736–746PubMedCrossRef
25.
go back to reference Essouri S, Durand P, Chevret L, Balu L, Devictor D, Fauroux B, Tissieres P (2011) Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis. Intensive Care Med 37:2002–2007PubMedCrossRef Essouri S, Durand P, Chevret L, Balu L, Devictor D, Fauroux B, Tissieres P (2011) Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis. Intensive Care Med 37:2002–2007PubMedCrossRef
26.
go back to reference Milesi C, Baleine J, Matecki S, Durand S, Combes C, Novais AR, Combonie G (2013) Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Intensive Care Med 39:1088–1094PubMedCrossRef Milesi C, Baleine J, Matecki S, Durand S, Combes C, Novais AR, Combonie G (2013) Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Intensive Care Med 39:1088–1094PubMedCrossRef
27.
go back to reference Milesi C, Matecki S, Jaber S, Mura T, Jacquot A, Pidoux O, Chautemps N, Novais AR, Combes C, Picaud JC, Cambonie G (2013) 6 cmH2O continuous positive airway pressure versus conventional oxygen therapy in severe viral bronchiolitis: a randomized trial. Pediatr Pulmonol 48:45–51PubMedCrossRef Milesi C, Matecki S, Jaber S, Mura T, Jacquot A, Pidoux O, Chautemps N, Novais AR, Combes C, Picaud JC, Cambonie G (2013) 6 cmH2O continuous positive airway pressure versus conventional oxygen therapy in severe viral bronchiolitis: a randomized trial. Pediatr Pulmonol 48:45–51PubMedCrossRef
28.
go back to reference Sinha IP, McBride AK, Smith R, Fernandes RM (2015) CPAP and high-flow nasal cannula oxygen in bronchiolitis. Chest 148:810–823PubMedCrossRef Sinha IP, McBride AK, Smith R, Fernandes RM (2015) CPAP and high-flow nasal cannula oxygen in bronchiolitis. Chest 148:810–823PubMedCrossRef
29.
go back to reference Fortenberry JD, Del Toro J, Jefferson LS, Evey L, Haase D (1995) Management of pediatric acute hypoxemic respiratory insufficiency with bilevel positive pressure (BiPAP) nasal mask ventilation. Chest 108:1059–1064PubMedCrossRef Fortenberry JD, Del Toro J, Jefferson LS, Evey L, Haase D (1995) Management of pediatric acute hypoxemic respiratory insufficiency with bilevel positive pressure (BiPAP) nasal mask ventilation. Chest 108:1059–1064PubMedCrossRef
30.
go back to reference Pancera CF, Hayashi M, Fregnani JH, Negri EM, Deheinzelin D, de Camargo B (2008) Noninvasive ventilation in immunocompromised pediatric patients: eight years of experience in a pediatric oncology intensive care unit. J Pediatr Hematol Oncol 30:533–538PubMedCrossRef Pancera CF, Hayashi M, Fregnani JH, Negri EM, Deheinzelin D, de Camargo B (2008) Noninvasive ventilation in immunocompromised pediatric patients: eight years of experience in a pediatric oncology intensive care unit. J Pediatr Hematol Oncol 30:533–538PubMedCrossRef
31.
go back to reference Schiller O, Schonfeld T, Yaniv I, Stein J, Kadmon G, Nahum E (2009) Bi-level positive airway pressure ventilation in pediatric oncology patients with acute respiratory failure. J Intensive Care Med 24:383–388PubMedCrossRef Schiller O, Schonfeld T, Yaniv I, Stein J, Kadmon G, Nahum E (2009) Bi-level positive airway pressure ventilation in pediatric oncology patients with acute respiratory failure. J Intensive Care Med 24:383–388PubMedCrossRef
32.
go back to reference Piastra M, De Luca D, Pietrini D, Pulitano S, D’Arrigo S, Mancino A, Conti G (2009) Noninvasive pressure-support ventilation in immunocompromised children with ARDS: a feasibility study. Intensive Care Med 35:1420–1427PubMedCrossRef Piastra M, De Luca D, Pietrini D, Pulitano S, D’Arrigo S, Mancino A, Conti G (2009) Noninvasive pressure-support ventilation in immunocompromised children with ARDS: a feasibility study. Intensive Care Med 35:1420–1427PubMedCrossRef
33.
go back to reference Gupta P, Kuperstock JE, Hashmi S, Arnolde V, Gossett JM, Prodhan P, Venkataraman S, Roth SJ (2013) Efficacy and predictors of success of noninvasive ventilation for prevention of extubation failure in critically ill children with heart disease. Pediatr Cardiol 34:964–977PubMedCrossRef Gupta P, Kuperstock JE, Hashmi S, Arnolde V, Gossett JM, Prodhan P, Venkataraman S, Roth SJ (2013) Efficacy and predictors of success of noninvasive ventilation for prevention of extubation failure in critically ill children with heart disease. Pediatr Cardiol 34:964–977PubMedCrossRef
34.
go back to reference Kovacikova L, Skrak P, Dobos D, Zahorec M (2014) Noninvasive positive pressure ventilation in critically ill children with cardiac disease. Pediatr Cardiol 35:676–683PubMedCrossRef Kovacikova L, Skrak P, Dobos D, Zahorec M (2014) Noninvasive positive pressure ventilation in critically ill children with cardiac disease. Pediatr Cardiol 35:676–683PubMedCrossRef
35.
go back to reference Chin K, Takahashi K, Ohmori K, Toru I, Matsumoto H, Niimi A, Doi H, Ikeda T, Nakahata T, Komeda M, Mishima M (2007) Noninvasive ventilation for pediatric patients under 1 year of age after cardiac surgery. J Thorac Cardiovasc Surg 134:260–261PubMedCrossRef Chin K, Takahashi K, Ohmori K, Toru I, Matsumoto H, Niimi A, Doi H, Ikeda T, Nakahata T, Komeda M, Mishima M (2007) Noninvasive ventilation for pediatric patients under 1 year of age after cardiac surgery. J Thorac Cardiovasc Surg 134:260–261PubMedCrossRef
36.
go back to reference Fernandez Lafever S, Toledo B, Leiva M, Padron M, Balseiro M, Carrillo A, Lopez- Herce J (2016) Non-invasive mechanical ventilation after heart surgery in children. BMC Pulm Med 16:167PubMedPubMedCentralCrossRef Fernandez Lafever S, Toledo B, Leiva M, Padron M, Balseiro M, Carrillo A, Lopez- Herce J (2016) Non-invasive mechanical ventilation after heart surgery in children. BMC Pulm Med 16:167PubMedPubMedCentralCrossRef
37.
go back to reference Thill PJ, McGuire JK, Baden HP, Green TP, Checchia PA (2004) Noninvasive positive-pressure ventilation in children with lower airway obstruction. Pediatr Crit Care Med 5:337–342PubMedCrossRef Thill PJ, McGuire JK, Baden HP, Green TP, Checchia PA (2004) Noninvasive positive-pressure ventilation in children with lower airway obstruction. Pediatr Crit Care Med 5:337–342PubMedCrossRef
38.
go back to reference Basnet S, Mander G, Andoh J, Klaska H, Verhulst S, Koirala J (2012) Safety, efficacy, and tolerability of early initiation of noninvasive positive pressure ventilation in pediatric patients admitted with status asthmaticus: a pilot study. Pediatr Crit Care Med 13:393–398PubMedCrossRef Basnet S, Mander G, Andoh J, Klaska H, Verhulst S, Koirala J (2012) Safety, efficacy, and tolerability of early initiation of noninvasive positive pressure ventilation in pediatric patients admitted with status asthmaticus: a pilot study. Pediatr Crit Care Med 13:393–398PubMedCrossRef
39.
go back to reference Piastra M, Antonelli M, Caresta E, Chiaretti A, Polidori G, Conti G (2006) Noninvasive ventilation in childhood acute neuromuscular respiratory failure: a pilot study. Respiration 73:791–798PubMedCrossRef Piastra M, Antonelli M, Caresta E, Chiaretti A, Polidori G, Conti G (2006) Noninvasive ventilation in childhood acute neuromuscular respiratory failure: a pilot study. Respiration 73:791–798PubMedCrossRef
40.
go back to reference Chen TH, Hsu JH, Wu JR, Dai ZK, Chen IC, Liang WC, Yang SN, Jong YJ (2014) Combined noninvasive ventilation and mechanical in-exsufflator in the treatment of pediatric acute neuromuscular respiratory failure. Pediatr Pulmonol 49:589–596PubMedCrossRef Chen TH, Hsu JH, Wu JR, Dai ZK, Chen IC, Liang WC, Yang SN, Jong YJ (2014) Combined noninvasive ventilation and mechanical in-exsufflator in the treatment of pediatric acute neuromuscular respiratory failure. Pediatr Pulmonol 49:589–596PubMedCrossRef
41.
go back to reference Demaret P, Mulder A, Loeckx I, Trippaerts M, Lebrun F (2015) Non-invasive ventilation is useful in paediatric intensive care units if children are appropriately selected and carefully monitored. Acta Paediatr 104:861–871PubMedCrossRef Demaret P, Mulder A, Loeckx I, Trippaerts M, Lebrun F (2015) Non-invasive ventilation is useful in paediatric intensive care units if children are appropriately selected and carefully monitored. Acta Paediatr 104:861–871PubMedCrossRef
42.
go back to reference Mayordomo-Colunga J, Medina A, Rey C, Concha A, Menendez S, Los Arcos M, Garcia I (2010) Non invasive ventilation after extubation in paediatric patients: a preliminary study. BMC Pediatr 10:29PubMedPubMedCentralCrossRef Mayordomo-Colunga J, Medina A, Rey C, Concha A, Menendez S, Los Arcos M, Garcia I (2010) Non invasive ventilation after extubation in paediatric patients: a preliminary study. BMC Pediatr 10:29PubMedPubMedCentralCrossRef
43.
go back to reference Fioretto JR, Ribeiro CF, Carpi MF, Bonatto RC, Moraes MA, Fioretto EB, Fagundes DJ (2015) Comparison between noninvasive mechanical ventilation and standard oxygen therapy in children up to 3 years old with respiratory failure after extubation: a pilot prospective randomized clinical study. Pediatr Crit Care Med 16:124–130PubMedCrossRef Fioretto JR, Ribeiro CF, Carpi MF, Bonatto RC, Moraes MA, Fioretto EB, Fagundes DJ (2015) Comparison between noninvasive mechanical ventilation and standard oxygen therapy in children up to 3 years old with respiratory failure after extubation: a pilot prospective randomized clinical study. Pediatr Crit Care Med 16:124–130PubMedCrossRef
44.
go back to reference Yanez LJ, Yunge M, Emilfork M, Lapadula M, Alcantara A, Fernandez C, Lozano J, Contreras M, Conto L, Arevalo C, Gayan A, Hernandez F, Pedraza M, Feddersen M, Bejares M, Morales M, Mallea F, Glasinovic M, Cavada G (2008) A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med 9:484–489PubMedCrossRef Yanez LJ, Yunge M, Emilfork M, Lapadula M, Alcantara A, Fernandez C, Lozano J, Contreras M, Conto L, Arevalo C, Gayan A, Hernandez F, Pedraza M, Feddersen M, Bejares M, Morales M, Mallea F, Glasinovic M, Cavada G (2008) A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med 9:484–489PubMedCrossRef
45.
go back to reference Calderini E, Chidini G, Pelosi P (2010) What are the current indications for noninvasive ventilation in children? Curr Opin Anaesthesiol 23:368–374PubMedCrossRef Calderini E, Chidini G, Pelosi P (2010) What are the current indications for noninvasive ventilation in children? Curr Opin Anaesthesiol 23:368–374PubMedCrossRef
46.
go back to reference Essouri S, Chevret L, Durand P, Haas V, Fauroux B, Devictor D (2006) Noninvasive positive pressure ventilation: five years of experience in a pediatric intensive care unit. Pediatr Crit Care Med 7:329–334PubMedCrossRef Essouri S, Chevret L, Durand P, Haas V, Fauroux B, Devictor D (2006) Noninvasive positive pressure ventilation: five years of experience in a pediatric intensive care unit. Pediatr Crit Care Med 7:329–334PubMedCrossRef
47.
go back to reference James CS, Hallewell CP, James DP, Wade A, Mok QQ (2011) Predicting the success of non-invasive ventilation in preventing intubation and re-intubation in the paediatric intensive care unit. Intensive Care Med 37:1994–2001PubMedCrossRef James CS, Hallewell CP, James DP, Wade A, Mok QQ (2011) Predicting the success of non-invasive ventilation in preventing intubation and re-intubation in the paediatric intensive care unit. Intensive Care Med 37:1994–2001PubMedCrossRef
48.
go back to reference Mayordomo-Colunga J, Medina A, Rey C, Diaz JJ, Concha A, Los Arcos M, Menendez S (2009) Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. Intensive Care Med 35:527–536PubMedCrossRef Mayordomo-Colunga J, Medina A, Rey C, Diaz JJ, Concha A, Los Arcos M, Menendez S (2009) Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. Intensive Care Med 35:527–536PubMedCrossRef
49.
go back to reference Munoz-Bonet JI, Flor-Macian EM, Brines J, Rosello-Millet PM, Cruz Llopis M, Lopez-Prats JL, Castillo S (2010) Predictive factors for the outcome of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med 11:675–680PubMedCrossRef Munoz-Bonet JI, Flor-Macian EM, Brines J, Rosello-Millet PM, Cruz Llopis M, Lopez-Prats JL, Castillo S (2010) Predictive factors for the outcome of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med 11:675–680PubMedCrossRef
50.
go back to reference Piastra M, De Luca D, Marzano L, Stival E, Genovese O, Pietrini D, Conti G (2011) The number of failing organs predicts non-invasive ventilation failure in children with ALI/ARDS. Intensive Care Med 37:1510–1516PubMedCrossRef Piastra M, De Luca D, Marzano L, Stival E, Genovese O, Pietrini D, Conti G (2011) The number of failing organs predicts non-invasive ventilation failure in children with ALI/ARDS. Intensive Care Med 37:1510–1516PubMedCrossRef
51.
go back to reference Antonelli M, Conti G, Esquinas A, Montini L, Maggiore SM, Bello G, Rocco M, Maviglia R, Pennisi MA, Gonzalez-Diaz G, Meduri GU (2007) A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome. Crit Care Med 35:18–25PubMedCrossRef Antonelli M, Conti G, Esquinas A, Montini L, Maggiore SM, Bello G, Rocco M, Maviglia R, Pennisi MA, Gonzalez-Diaz G, Meduri GU (2007) A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome. Crit Care Med 35:18–25PubMedCrossRef
52.
go back to reference Crulli B, Loron G, Nishisaki A, Harrington K, Essouri S, Emeriaud G (2016) Safety of paediatric tracheal intubation after non-invasive ventilation failure. Pediatr Pulmonol 51:165–172PubMedCrossRef Crulli B, Loron G, Nishisaki A, Harrington K, Essouri S, Emeriaud G (2016) Safety of paediatric tracheal intubation after non-invasive ventilation failure. Pediatr Pulmonol 51:165–172PubMedCrossRef
53.
go back to reference Bernet V, Hug MI, Frey B (2005) Predictive factors for the success of noninvasive mask ventilation in infants and children with acute respiratory failure. Pediatr Crit Care Med 6:660–664PubMedCrossRef Bernet V, Hug MI, Frey B (2005) Predictive factors for the success of noninvasive mask ventilation in infants and children with acute respiratory failure. Pediatr Crit Care Med 6:660–664PubMedCrossRef
54.
go back to reference Habashi NM (2005) Other approaches to open-lung ventilation: airway pressure release ventilation. Crit Care Med 33:S228–S240PubMedCrossRef Habashi NM (2005) Other approaches to open-lung ventilation: airway pressure release ventilation. Crit Care Med 33:S228–S240PubMedCrossRef
55.
go back to reference Yehya N, Topjian AA, Thomas NJ, Friess SH (2014) Improved oxygenation 24 hours after transition to airway pressure release ventilation or high-frequency oscillatory ventilation accurately discriminates survival in immunocompromised pediatric patients with acute respiratory distress syndrome. Pediatr Crit Care Med 15:e147–e156PubMedPubMedCentralCrossRef Yehya N, Topjian AA, Thomas NJ, Friess SH (2014) Improved oxygenation 24 hours after transition to airway pressure release ventilation or high-frequency oscillatory ventilation accurately discriminates survival in immunocompromised pediatric patients with acute respiratory distress syndrome. Pediatr Crit Care Med 15:e147–e156PubMedPubMedCentralCrossRef
56.
go back to reference Yehya N, Topjian AA, Lin R, Berg RA, Thomas NJ, Friess SH (2014) High frequency oscillation and airway pressure release ventilation in pediatric respiratory failure. Pediatr Pulmonol 49:707–715PubMedCrossRef Yehya N, Topjian AA, Lin R, Berg RA, Thomas NJ, Friess SH (2014) High frequency oscillation and airway pressure release ventilation in pediatric respiratory failure. Pediatr Pulmonol 49:707–715PubMedCrossRef
57.
go back to reference Walsh MA, Merat M, La Rotta G, Joshi P, Joshi V, Tran T, Jarvis S, Caldarone CA, Van Arsdell GS, Redington AN, Kavanagh BP (2011) Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med 39:2599–2604PubMedCrossRef Walsh MA, Merat M, La Rotta G, Joshi P, Joshi V, Tran T, Jarvis S, Caldarone CA, Van Arsdell GS, Redington AN, Kavanagh BP (2011) Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med 39:2599–2604PubMedCrossRef
58.
go back to reference Krishnan J, Morrison W (2007) Airway pressure release ventilation: a pediatric case series. Pediatr Pulmonol 42:83–88PubMedCrossRef Krishnan J, Morrison W (2007) Airway pressure release ventilation: a pediatric case series. Pediatr Pulmonol 42:83–88PubMedCrossRef
59.
go back to reference de Carvalho WB, Kopelman BI, Gurgueira GL, Bonassa J (2000) Airway pressure release in postoperative cardiac surgery in pediatric patients. Rev Assoc Med Bras 46:166–173PubMedCrossRef de Carvalho WB, Kopelman BI, Gurgueira GL, Bonassa J (2000) Airway pressure release in postoperative cardiac surgery in pediatric patients. Rev Assoc Med Bras 46:166–173PubMedCrossRef
60.
go back to reference Medina A, Modesto-Alapont V, Lobete C, Vidal-Mico S, Alvarez-Caro F, Pons- Odena M, Mayordomo-Colunga J, Ibiza-Palacios E (2014) Is pressure-regulated volume control mode appropriate for severely obstructed patients? J Crit Care 29:1041–1045PubMedCrossRef Medina A, Modesto-Alapont V, Lobete C, Vidal-Mico S, Alvarez-Caro F, Pons- Odena M, Mayordomo-Colunga J, Ibiza-Palacios E (2014) Is pressure-regulated volume control mode appropriate for severely obstructed patients? J Crit Care 29:1041–1045PubMedCrossRef
61.
go back to reference Brenner B, Corbridge T, Kazzi A (2009) Intubation and mechanical ventilation of the asthmatic patient in respiratory failure. Proc Am Thorac Soc 6:371–379PubMedCrossRef Brenner B, Corbridge T, Kazzi A (2009) Intubation and mechanical ventilation of the asthmatic patient in respiratory failure. Proc Am Thorac Soc 6:371–379PubMedCrossRef
62.
go back to reference Arnold JH, Hanson JH, Toro-Figuero LO, Gutierrez J, Berens RJ, Anglin DL (1994) Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Crit Care Med 22:1530–1539PubMedCrossRef Arnold JH, Hanson JH, Toro-Figuero LO, Gutierrez J, Berens RJ, Anglin DL (1994) Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Crit Care Med 22:1530–1539PubMedCrossRef
63.
go back to reference Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, Kacmarek RM, Wetzel RC (2014) Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. JAMA Pediatr 168(3):243–249PubMedCrossRef Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, Kacmarek RM, Wetzel RC (2014) Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. JAMA Pediatr 168(3):243–249PubMedCrossRef
64.
go back to reference Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA, Investigators RS (2016) Early high-frequency oscillatory ventilation in pediatric acute respiratory failure. a propensity score analysis. Am J Respir Crit Care Med 193:495–503PubMedPubMedCentralCrossRef Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA, Investigators RS (2016) Early high-frequency oscillatory ventilation in pediatric acute respiratory failure. a propensity score analysis. Am J Respir Crit Care Med 193:495–503PubMedPubMedCentralCrossRef
65.
go back to reference Kneyber MC, van Heerde M, Markhorst DG (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:861PubMedCrossRef Kneyber MC, van Heerde M, Markhorst DG (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:861PubMedCrossRef
66.
go back to reference Rimensberger PC, Bachman TE (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:862–863PubMedCrossRef Rimensberger PC, Bachman TE (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:862–863PubMedCrossRef
67.
go back to reference Essouri S, Emeriaud G, Jouvet P (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:861–862PubMedCrossRef Essouri S, Emeriaud G, Jouvet P (2014) It is too early to declare early or late rescue high-frequency oscillatory ventilation dead. JAMA Pediatr 168:861–862PubMedCrossRef
68.
go back to reference Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO, Investigators OT, Canadian Critical Care Trials G (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 368:795–805PubMedCrossRef Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO, Investigators OT, Canadian Critical Care Trials G (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 368:795–805PubMedCrossRef
69.
go back to reference Kneyber MC, van Heerde M, Markhorst DG (2012) Reflections on pediatric high- frequency oscillatory ventilation from a physiologic perspective. Respir Care 57:1496–1504PubMedCrossRef Kneyber MC, van Heerde M, Markhorst DG (2012) Reflections on pediatric high- frequency oscillatory ventilation from a physiologic perspective. Respir Care 57:1496–1504PubMedCrossRef
70.
go back to reference Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, Adhikari NK (2010) High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis. BMJ 340:c2327PubMedCrossRef Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, Adhikari NK (2010) High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis. BMJ 340:c2327PubMedCrossRef
71.
go back to reference Young D, Lamb SE, Shah S, MacKenzie I, Tunnicliffe W, Lall R, Rowan K, Cuthbertson BH, Group OS (2013) High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med 368:806–813PubMedCrossRef Young D, Lamb SE, Shah S, MacKenzie I, Tunnicliffe W, Lall R, Rowan K, Cuthbertson BH, Group OS (2013) High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med 368:806–813PubMedCrossRef
72.
go back to reference Bojan M, Gioanni S, Mauriat P, Pouard P (2011) High-frequency oscillatory ventilation and short-term outcome in neonates and infants undergoing cardiac surgery: a propensity score analysis. Crit Care 15:R259PubMedPubMedCentralCrossRef Bojan M, Gioanni S, Mauriat P, Pouard P (2011) High-frequency oscillatory ventilation and short-term outcome in neonates and infants undergoing cardiac surgery: a propensity score analysis. Crit Care 15:R259PubMedPubMedCentralCrossRef
73.
go back to reference Li S, Wang X, Li S, Yan J (2013) High-frequency oscillatory ventilation for cardiac surgery children with severe acute respiratory distress syndrome. Pediatr Cardiol 34:1382–1388PubMedCrossRef Li S, Wang X, Li S, Yan J (2013) High-frequency oscillatory ventilation for cardiac surgery children with severe acute respiratory distress syndrome. Pediatr Cardiol 34:1382–1388PubMedCrossRef
74.
go back to reference Kornecki A, Shekerdemian LS, Adatia I, Bohn D (2002) High-frequency oscillation in children after Fontan operation. Pediatr Crit Care Med 3:144–147PubMedCrossRef Kornecki A, Shekerdemian LS, Adatia I, Bohn D (2002) High-frequency oscillation in children after Fontan operation. Pediatr Crit Care Med 3:144–147PubMedCrossRef
75.
go back to reference Duval EL, Leroy PL, Gemke RJ, van Vught AJ (1999) High-frequency oscillatory ventilation in RSV bronchiolitis patients. Respir Med 93:435–440PubMedCrossRef Duval EL, Leroy PL, Gemke RJ, van Vught AJ (1999) High-frequency oscillatory ventilation in RSV bronchiolitis patients. Respir Med 93:435–440PubMedCrossRef
76.
go back to reference Duval EL, Markhorst DG, Gemke RJ, van Vught AJ (2000) High-frequency oscillatory ventilation in pediatric patients. Neth J Med 56:177–185PubMedCrossRef Duval EL, Markhorst DG, Gemke RJ, van Vught AJ (2000) High-frequency oscillatory ventilation in pediatric patients. Neth J Med 56:177–185PubMedCrossRef
77.
go back to reference Duval ELIM, van Vught AJ (2000) Status asthmaticus treated by high-frequency oscillatory ventilation. Pediatr Pulmonol 30:350–353PubMedCrossRef Duval ELIM, van Vught AJ (2000) Status asthmaticus treated by high-frequency oscillatory ventilation. Pediatr Pulmonol 30:350–353PubMedCrossRef
78.
go back to reference Kneyber MC, Plotz FB, Sibarani-Ponsen RD, Markhorst DG (2005) High-frequency oscillatory ventilation (HFOV) facilitates CO2 elimination in small airway disease: the open airway concept. Respir Med 99:1459–1461PubMedCrossRef Kneyber MC, Plotz FB, Sibarani-Ponsen RD, Markhorst DG (2005) High-frequency oscillatory ventilation (HFOV) facilitates CO2 elimination in small airway disease: the open airway concept. Respir Med 99:1459–1461PubMedCrossRef
79.
go back to reference Davis DA, Russo PA, Greenspan JS, Speziali G, Spitzer A (1994) High-frequency jet versus conventional ventilation in infants undergoing Blalock-Taussig shunts. Ann Thorac Surg 57:846–849PubMedCrossRef Davis DA, Russo PA, Greenspan JS, Speziali G, Spitzer A (1994) High-frequency jet versus conventional ventilation in infants undergoing Blalock-Taussig shunts. Ann Thorac Surg 57:846–849PubMedCrossRef
80.
go back to reference Kocis KC, Meliones JN, Dekeon MK, Callow LB, Lupinetti FM, Bove EL (1992) High-frequency jet ventilation for respiratory failure after congenital heart surgery. Circulation 86:II127–II132PubMed Kocis KC, Meliones JN, Dekeon MK, Callow LB, Lupinetti FM, Bove EL (1992) High-frequency jet ventilation for respiratory failure after congenital heart surgery. Circulation 86:II127–II132PubMed
81.
go back to reference Meliones JN, Bove EL, Dekeon MK, Custer JR, Moler FW, Callow LR, Wilton NC, Rosen DB (1991) High-frequency jet ventilation improves cardiac function after the Fontan procedure. Circulation 84:III364–III368PubMed Meliones JN, Bove EL, Dekeon MK, Custer JR, Moler FW, Callow LR, Wilton NC, Rosen DB (1991) High-frequency jet ventilation improves cardiac function after the Fontan procedure. Circulation 84:III364–III368PubMed
82.
go back to reference Rizkalla NA, Dominick CL, Fitzgerald JC, Thomas NJ, Yehya N (2014) High- frequency percussive ventilation improves oxygenation and ventilation in pediatric patients with acute respiratory failure. J Crit Care 29(314):e311–e317 Rizkalla NA, Dominick CL, Fitzgerald JC, Thomas NJ, Yehya N (2014) High- frequency percussive ventilation improves oxygenation and ventilation in pediatric patients with acute respiratory failure. J Crit Care 29(314):e311–e317
83.
go back to reference Cortiella J, Mlcak R, Herndon D (1999) High frequency percussive ventilation in pediatric patients with inhalation injury. J Burn Care Rehabil 20:232–235PubMedCrossRef Cortiella J, Mlcak R, Herndon D (1999) High frequency percussive ventilation in pediatric patients with inhalation injury. J Burn Care Rehabil 20:232–235PubMedCrossRef
84.
go back to reference Yehya N, Dominick CL, Connelly JT, Davis DH, Minneci PC, Deans KJ, McCloskey JJ, Kilbaugh TJ (2014) High-frequency percussive ventilation and bronchoscopy during extracorporeal life support in children. ASAIO J 60:424–428PubMedCrossRef Yehya N, Dominick CL, Connelly JT, Davis DH, Minneci PC, Deans KJ, McCloskey JJ, Kilbaugh TJ (2014) High-frequency percussive ventilation and bronchoscopy during extracorporeal life support in children. ASAIO J 60:424–428PubMedCrossRef
85.
go back to reference Carman B, Cahill T, Warden G, McCall J (2002) A prospective, randomized comparison of the Volume Diffusive Respirator vs conventional ventilation for ventilation of burned children. 2001 ABA paper. J Burn Care Rehabil 23:444–448PubMedCrossRef Carman B, Cahill T, Warden G, McCall J (2002) A prospective, randomized comparison of the Volume Diffusive Respirator vs conventional ventilation for ventilation of burned children. 2001 ABA paper. J Burn Care Rehabil 23:444–448PubMedCrossRef
86.
go back to reference MacLaren G, Dodge-Khatami A, Dalton HJ, Writing C, MacLaren G, Dodge- Khatami A, Dalton HJ, Adachi I, Almodovar M, Annich G, Bartlett R, Bronicki R, Brown K, Butt W, Cooper D, Demuth M, D’Udekem Y, Fraser C, Guerguerian AM, Heard M, Horton S, Ichord R, Jaquiss R, Laussen P, Lequier L, Lou S, Marino B, McMullan M, Ogino M, Peek G, Pretre R, Rodefeld M, Schmidt A, Schwartz S, Shekerdemian L, Shime N, Sivarajan B, Stiller B, Thiagarajan R (2013) Joint statement on mechanical circulatory support in children: a consensus review from the Pediatric Cardiac Intensive Care Society and Extracorporeal Life Support Organization. Pediatr Crit Care Med 14:S1–S2PubMedCrossRef MacLaren G, Dodge-Khatami A, Dalton HJ, Writing C, MacLaren G, Dodge- Khatami A, Dalton HJ, Adachi I, Almodovar M, Annich G, Bartlett R, Bronicki R, Brown K, Butt W, Cooper D, Demuth M, D’Udekem Y, Fraser C, Guerguerian AM, Heard M, Horton S, Ichord R, Jaquiss R, Laussen P, Lequier L, Lou S, Marino B, McMullan M, Ogino M, Peek G, Pretre R, Rodefeld M, Schmidt A, Schwartz S, Shekerdemian L, Shime N, Sivarajan B, Stiller B, Thiagarajan R (2013) Joint statement on mechanical circulatory support in children: a consensus review from the Pediatric Cardiac Intensive Care Society and Extracorporeal Life Support Organization. Pediatr Crit Care Med 14:S1–S2PubMedCrossRef
87.
go back to reference Blokpoel RG, Burgerhof JG, Markhorst DG, Kneyber MC (2016) Patient–ventilator asynchrony during assisted ventilation in children. Pediatr Crit Care Med 17:e204–e211PubMedCrossRef Blokpoel RG, Burgerhof JG, Markhorst DG, Kneyber MC (2016) Patient–ventilator asynchrony during assisted ventilation in children. Pediatr Crit Care Med 17:e204–e211PubMedCrossRef
88.
go back to reference Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Jaecklin T, Levy-Jamet Y, Tourneux P, Jolliet P, Rimensberger PC (2013) Optimizing patient–ventilator synchrony during invasive ventilator assist in children and infants remains a difficult task. Pediatr Crit Care Med 14:e316–e325PubMedCrossRef Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Jaecklin T, Levy-Jamet Y, Tourneux P, Jolliet P, Rimensberger PC (2013) Optimizing patient–ventilator synchrony during invasive ventilator assist in children and infants remains a difficult task. Pediatr Crit Care Med 14:e316–e325PubMedCrossRef
89.
go back to reference Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Levy-Jamet Y, Jaecklin T, Tourneux P, Jolliet P, Rimensberger PC (2013) Patient-ventilator asynchrony during noninvasive pressure support ventilation and neurally adjusted ventilatory assist in infants and children. Pediatr Crit Care Med 14:e357–e364PubMedCrossRef Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Levy-Jamet Y, Jaecklin T, Tourneux P, Jolliet P, Rimensberger PC (2013) Patient-ventilator asynchrony during noninvasive pressure support ventilation and neurally adjusted ventilatory assist in infants and children. Pediatr Crit Care Med 14:e357–e364PubMedCrossRef
90.
go back to reference de la Oliva P, Schuffelmann C, Gomez-Zamora A, Villar J, Kacmarek RM (2012) Asynchrony, neural drive, ventilatory variability and COMFORT: NAVA versus pressure support in pediatric patients. A non-randomized cross-over trial. Intensive Care Med 38:838–846PubMedCrossRef de la Oliva P, Schuffelmann C, Gomez-Zamora A, Villar J, Kacmarek RM (2012) Asynchrony, neural drive, ventilatory variability and COMFORT: NAVA versus pressure support in pediatric patients. A non-randomized cross-over trial. Intensive Care Med 38:838–846PubMedCrossRef
91.
go back to reference Piastra M, De Luca D, Costa R, Pizza A, De Sanctis R, Marzano L, Biasucci D, Visconti F, Conti G (2014) Neurally adjusted ventilatory assist vs pressure support ventilation in infants recovering from severe acute respiratory distress syndrome: nested study. J Crit Care 29(312):e311–e315 Piastra M, De Luca D, Costa R, Pizza A, De Sanctis R, Marzano L, Biasucci D, Visconti F, Conti G (2014) Neurally adjusted ventilatory assist vs pressure support ventilation in infants recovering from severe acute respiratory distress syndrome: nested study. J Crit Care 29(312):e311–e315
92.
go back to reference Kallio M, Peltoniemi O, Anttila E, Pokka T, Kontiokari T (2015) Neurally adjusted ventilatory assist (NAVA) in pediatric intensive care-a randomized controlled trial. Pediatr Pulmonol 50:55–62PubMedCrossRef Kallio M, Peltoniemi O, Anttila E, Pokka T, Kontiokari T (2015) Neurally adjusted ventilatory assist (NAVA) in pediatric intensive care-a randomized controlled trial. Pediatr Pulmonol 50:55–62PubMedCrossRef
93.
go back to reference Froese AB, Bryan AC (1974) Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41:242–255PubMedCrossRef Froese AB, Bryan AC (1974) Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41:242–255PubMedCrossRef
94.
go back to reference Putensen C, Hering R, Muders T, Wrigge H (2005) Assisted breathing is better in acute respiratory failure. Curr Opin Crit Care 11:63–68PubMedCrossRef Putensen C, Hering R, Muders T, Wrigge H (2005) Assisted breathing is better in acute respiratory failure. Curr Opin Crit Care 11:63–68PubMedCrossRef
95.
go back to reference Putensen C, Muders T, Varelmann D, Wrigge H (2006) The impact of spontaneous breathing during mechanical ventilation. Curr Opin Crit Care 12:13–18PubMedCrossRef Putensen C, Muders T, Varelmann D, Wrigge H (2006) The impact of spontaneous breathing during mechanical ventilation. Curr Opin Crit Care 12:13–18PubMedCrossRef
96.
go back to reference Petrof BJ, Hussain SN (2016) Ventilator-induced diaphragmatic dysfunction: what have we learned? Curr Opin Crit Care 22:67–72PubMedCrossRef Petrof BJ, Hussain SN (2016) Ventilator-induced diaphragmatic dysfunction: what have we learned? Curr Opin Crit Care 22:67–72PubMedCrossRef
97.
go back to reference Emeriaud G, Larouche A, Ducharme-Crevier L, Massicotte E, Flechelles O, Pellerin- Leblanc AA, Morneau S, Beck J, Jouvet P (2014) Evolution of inspiratory diaphragm activity in children over the course of the PICU stay. Intensive Care Med 40:1718–1726PubMedCrossRef Emeriaud G, Larouche A, Ducharme-Crevier L, Massicotte E, Flechelles O, Pellerin- Leblanc AA, Morneau S, Beck J, Jouvet P (2014) Evolution of inspiratory diaphragm activity in children over the course of the PICU stay. Intensive Care Med 40:1718–1726PubMedCrossRef
98.
go back to reference Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, Jaber S, Arnal JM, Perez D, Seghboyan JM, Constantin JM, Courant P, Lefrant JY, Guerin C, Prat G, Morange S, Roch A (2010) Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:1107–1116PubMedCrossRef Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, Jaber S, Arnal JM, Perez D, Seghboyan JM, Constantin JM, Courant P, Lefrant JY, Guerin C, Prat G, Morange S, Roch A (2010) Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 363:1107–1116PubMedCrossRef
99.
go back to reference Wilsterman ME, de Jager P, Blokpoel R, Frerichs I, Dijkstra SK, Albers MJ, Burgerhof JG, Markhorst DG, Kneyber MC (2016) Short-term effects of neuromuscular blockade on global and regional lung mechanics, oxygenation and ventilation in pediatric acute hypoxemic respiratory failure. Ann Intensive Care 6:103PubMedPubMedCentralCrossRef Wilsterman ME, de Jager P, Blokpoel R, Frerichs I, Dijkstra SK, Albers MJ, Burgerhof JG, Markhorst DG, Kneyber MC (2016) Short-term effects of neuromuscular blockade on global and regional lung mechanics, oxygenation and ventilation in pediatric acute hypoxemic respiratory failure. Ann Intensive Care 6:103PubMedPubMedCentralCrossRef
100.
go back to reference Erickson S, Schibler A, Numa A, Nuthall G, Yung M, Pascoe E, Wilkins B (2007) Acute lung injury in pediatric intensive care in Australia and New Zealand: a prospective, multicenter, observational study. Pediatr Crit Care Med 8:317–323PubMed Erickson S, Schibler A, Numa A, Nuthall G, Yung M, Pascoe E, Wilkins B (2007) Acute lung injury in pediatric intensive care in Australia and New Zealand: a prospective, multicenter, observational study. Pediatr Crit Care Med 8:317–323PubMed
101.
go back to reference Khemani RG, Conti D, Alonzo TA, Bart RD III, Newth CJ (2009) Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med 35:1428–1437PubMedCrossRef Khemani RG, Conti D, Alonzo TA, Bart RD III, Newth CJ (2009) Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med 35:1428–1437PubMedCrossRef
102.
go back to reference Flori HR, Glidden DV, Rutherford GW, Matthay MA (2005) Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med 171:995–1001PubMedCrossRef Flori HR, Glidden DV, Rutherford GW, Matthay MA (2005) Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med 171:995–1001PubMedCrossRef
103.
go back to reference Panico FF, Troster EJ, Oliveira CS, Faria A, Lucena M, Joao PR, Saad ED, Foronda FA, Delgado AF, de Carvalho WB (2015) Risk factors for mortality and outcomes in pediatric acute lung injury/acute respiratory distress syndrome. Pediatr Crit Care Med 16:e194–e200PubMedCrossRef Panico FF, Troster EJ, Oliveira CS, Faria A, Lucena M, Joao PR, Saad ED, Foronda FA, Delgado AF, de Carvalho WB (2015) Risk factors for mortality and outcomes in pediatric acute lung injury/acute respiratory distress syndrome. Pediatr Crit Care Med 16:e194–e200PubMedCrossRef
104.
go back to reference Chiumello D, Carlesso E, Cadringher P, Caironi P, Valenza F, Polli F, Tallarini F, Cozzi P, Cressoni M, Colombo A, Marini JJ, Gattinoni L (2008) Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am J Respir Crit Care Med 178:346–355PubMedCrossRef Chiumello D, Carlesso E, Cadringher P, Caironi P, Valenza F, Polli F, Tallarini F, Cozzi P, Cressoni M, Colombo A, Marini JJ, Gattinoni L (2008) Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am J Respir Crit Care Med 178:346–355PubMedCrossRef
105.
go back to reference Chiumello D, Chidini G, Calderini E, Colombo A, Crimella F, Brioni M (2016) Respiratory mechanics and lung stress/strain in children with acute respiratory distress syndrome. Ann Intensive care 6:11PubMedPubMedCentralCrossRef Chiumello D, Chidini G, Calderini E, Colombo A, Crimella F, Brioni M (2016) Respiratory mechanics and lung stress/strain in children with acute respiratory distress syndrome. Ann Intensive care 6:11PubMedPubMedCentralCrossRef
106.
go back to reference Rimensberger PC, Cheifetz IM, Pediatric Acute Lung Injury Consensus Conference G (2015) Ventilatory support in children with pediatric acute respiratory distress syndrome: proceedings from the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med 16:S51–S60PubMedCrossRef Rimensberger PC, Cheifetz IM, Pediatric Acute Lung Injury Consensus Conference G (2015) Ventilatory support in children with pediatric acute respiratory distress syndrome: proceedings from the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med 16:S51–S60PubMedCrossRef
107.
go back to reference Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, Stewart TE, Briel M, Talmor D, Mercat A, Richard JC, Carvalho CR, Brower RG (2015) Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 372:747–755PubMedCrossRef Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, Stewart TE, Briel M, Talmor D, Mercat A, Richard JC, Carvalho CR, Brower RG (2015) Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 372:747–755PubMedCrossRef
108.
go back to reference de Jager P, Burgerhof JG, van Heerde M, Albers MJ, Markhorst DG, Kneyber MC (2014) Tidal volume and mortality in mechanically ventilated children: a systematic review and meta-analysis of observational studies. Crit Care Med 42:2461–2472PubMedCrossRef de Jager P, Burgerhof JG, van Heerde M, Albers MJ, Markhorst DG, Kneyber MC (2014) Tidal volume and mortality in mechanically ventilated children: a systematic review and meta-analysis of observational studies. Crit Care Med 42:2461–2472PubMedCrossRef
109.
go back to reference Kneyber MC, Rimensberger PC (2012) The need for and feasibility of a pediatric ventilation trial: reflections on a survey among pediatric intensivists. Pediatr Crit Care Med 13:632–638PubMedCrossRef Kneyber MC, Rimensberger PC (2012) The need for and feasibility of a pediatric ventilation trial: reflections on a survey among pediatric intensivists. Pediatr Crit Care Med 13:632–638PubMedCrossRef
110.
go back to reference Yu WL, Lu ZJ, Wang Y, Shi LP, Kuang FW, Qian SY, Zeng QY, Xie MH, Zhang GY, Zhuang DY, Fan XM, Sun B, Collaborative Study Group of Pediatric Respiratory F (2009) The epidemiology of acute respiratory distress syndrome in pediatric intensive care units in China. Intensive Care Med 35:136–143PubMedCrossRef Yu WL, Lu ZJ, Wang Y, Shi LP, Kuang FW, Qian SY, Zeng QY, Xie MH, Zhang GY, Zhuang DY, Fan XM, Sun B, Collaborative Study Group of Pediatric Respiratory F (2009) The epidemiology of acute respiratory distress syndrome in pediatric intensive care units in China. Intensive Care Med 35:136–143PubMedCrossRef
111.
go back to reference Zhu YF, Xu F, Lu XL, Wang Y, Chen JL, Chao JX, Zhou XW, Zhang JH, Huang YZ, Yu WL, Xie MH, Yan CY, Lu ZJ, Sun B, Chinese Collaborative Study Group for Pediatric Hypoxemic Respiratory F (2012) Mortality and morbidity of acute hypoxemic respiratory failure and acute respiratory distress syndrome in infants and young children. Chin Med J 125:2265–2271PubMed Zhu YF, Xu F, Lu XL, Wang Y, Chen JL, Chao JX, Zhou XW, Zhang JH, Huang YZ, Yu WL, Xie MH, Yan CY, Lu ZJ, Sun B, Chinese Collaborative Study Group for Pediatric Hypoxemic Respiratory F (2012) Mortality and morbidity of acute hypoxemic respiratory failure and acute respiratory distress syndrome in infants and young children. Chin Med J 125:2265–2271PubMed
112.
go back to reference Albuali WH, Singh RN, Fraser DD, Seabrook JA, Kavanagh BP, Parshuram CS, Komecki A (2007) Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med 8:324–330PubMed Albuali WH, Singh RN, Fraser DD, Seabrook JA, Kavanagh BP, Parshuram CS, Komecki A (2007) Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med 8:324–330PubMed
113.
go back to reference Pulitano S, Mancino A, Pietrini D, Piastra M, De Rosa S, Tosi F, De Luca D, Conti G (2013) Effects of positive end expiratory pressure (PEEP) on intracranial and cerebral perfusion pressure in pediatric neurosurgical patients. J Neurosurg Anesthesiol 25:330–334PubMedCrossRef Pulitano S, Mancino A, Pietrini D, Piastra M, De Rosa S, Tosi F, De Luca D, Conti G (2013) Effects of positive end expiratory pressure (PEEP) on intracranial and cerebral perfusion pressure in pediatric neurosurgical patients. J Neurosurg Anesthesiol 25:330–334PubMedCrossRef
114.
go back to reference von Ungern-Sternberg BS, Regli A, Schibler A, Hammer J, Frei FJ, Erb TO (2007) The impact of positive end-expiratory pressure on functional residual capacity and ventilation homogeneity impairment in anesthetized children exposed to high levels of inspired oxygen. Anesth Analg 104:1364–1368CrossRef von Ungern-Sternberg BS, Regli A, Schibler A, Hammer J, Frei FJ, Erb TO (2007) The impact of positive end-expiratory pressure on functional residual capacity and ventilation homogeneity impairment in anesthetized children exposed to high levels of inspired oxygen. Anesth Analg 104:1364–1368CrossRef
115.
go back to reference Tusman G, Bohm SH, Tempra A, Melkun F, Garcia E, Turchetto E, Mulder PG, Lachmann B (2003) Effects of recruitment maneuver on atelectasis in anesthetized children. Anesthesiology 98:14–22PubMedCrossRef Tusman G, Bohm SH, Tempra A, Melkun F, Garcia E, Turchetto E, Mulder PG, Lachmann B (2003) Effects of recruitment maneuver on atelectasis in anesthetized children. Anesthesiology 98:14–22PubMedCrossRef
116.
go back to reference Russell RI, Greenough A, Giffin F (1993) The effect of variations in positive end expiratory pressure on gas exchange in ventilated children with liver disease. Eur J Pediatr 152:742–744PubMedCrossRef Russell RI, Greenough A, Giffin F (1993) The effect of variations in positive end expiratory pressure on gas exchange in ventilated children with liver disease. Eur J Pediatr 152:742–744PubMedCrossRef
117.
go back to reference Giffin F, Greenough A (1994) Effect of positive end expiratory pressure and mean airway pressure on respiratory compliance and gas exchange in children with liver disease. Eur J Pediatr 153:28–33PubMedCrossRef Giffin F, Greenough A (1994) Effect of positive end expiratory pressure and mean airway pressure on respiratory compliance and gas exchange in children with liver disease. Eur J Pediatr 153:28–33PubMedCrossRef
118.
go back to reference Ingaramo OA, Ngo T, Khemani RG, Newth CJ (2014) Impact of positive end- expiratory pressure on cardiac index measured by ultrasound cardiac output monitor. Pediatr Crit Care Med 15:15–20PubMedCrossRef Ingaramo OA, Ngo T, Khemani RG, Newth CJ (2014) Impact of positive end- expiratory pressure on cardiac index measured by ultrasound cardiac output monitor. Pediatr Crit Care Med 15:15–20PubMedCrossRef
119.
120.
go back to reference Paulson TE, Spear RM, Silva PD, Peterson BM (1996) High-frequency pressure- control ventilation with high positive end-expiratory pressure in children with acute respiratory distress syndrome. J Pediatr 129:566–573PubMedCrossRef Paulson TE, Spear RM, Silva PD, Peterson BM (1996) High-frequency pressure- control ventilation with high positive end-expiratory pressure in children with acute respiratory distress syndrome. J Pediatr 129:566–573PubMedCrossRef
121.
go back to reference Sivan Y, Deakers TW, Newth CJ (1991) Effect of positive end-expiratory pressure on respiratory compliance in children with acute respiratory failure. Pediatr Pulmonol 11:103–107PubMedCrossRef Sivan Y, Deakers TW, Newth CJ (1991) Effect of positive end-expiratory pressure on respiratory compliance in children with acute respiratory failure. Pediatr Pulmonol 11:103–107PubMedCrossRef
122.
go back to reference White MK, Galli SA, Chatburn RL, Blumer JL (1988) Optimal positive end-expiratory pressure therapy in infants and children with acute respiratory failure. Pediatr Res 24:217–221PubMedCrossRef White MK, Galli SA, Chatburn RL, Blumer JL (1988) Optimal positive end-expiratory pressure therapy in infants and children with acute respiratory failure. Pediatr Res 24:217–221PubMedCrossRef
123.
go back to reference Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJ (2007) Positive end-expiratory pressure and pressure support in peripheral airways obstruction: work of breathing in intubated children. Intensive Care Med 33:120–127PubMedCrossRef Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJ (2007) Positive end-expiratory pressure and pressure support in peripheral airways obstruction: work of breathing in intubated children. Intensive Care Med 33:120–127PubMedCrossRef
124.
go back to reference Parrilla FJ, Moran I, Roche-Campo F, Mancebo J (2014) Ventilatory strategies in obstructive lung disease. Semin Resp Crit Care Med 35:431–440CrossRef Parrilla FJ, Moran I, Roche-Campo F, Mancebo J (2014) Ventilatory strategies in obstructive lung disease. Semin Resp Crit Care Med 35:431–440CrossRef
125.
go back to reference Caramez MP, Borges JB, Tucci MR, Okamoto VN, Carvalho CR, Kacmarek RM, Malhotra A, Velasco IT, Amato MB (2005) Paradoxical responses to positive end- expiratory pressure in patients with airway obstruction during controlled ventilation. Crit Care Med 33:1519–1528PubMedPubMedCentralCrossRef Caramez MP, Borges JB, Tucci MR, Okamoto VN, Carvalho CR, Kacmarek RM, Malhotra A, Velasco IT, Amato MB (2005) Paradoxical responses to positive end- expiratory pressure in patients with airway obstruction during controlled ventilation. Crit Care Med 33:1519–1528PubMedPubMedCentralCrossRef
127.
go back to reference Davis S, Jones M, Kisling J, Angelicchio C, Tepper RS (1998) Effect of continuous positive airway pressure on forced expiratory flows in infants with tracheomalacia. Am J Respir Crit Care Med 158:148–152PubMedCrossRef Davis S, Jones M, Kisling J, Angelicchio C, Tepper RS (1998) Effect of continuous positive airway pressure on forced expiratory flows in infants with tracheomalacia. Am J Respir Crit Care Med 158:148–152PubMedCrossRef
128.
go back to reference Essouri S, Nicot F, Clement A, Garabedian EN, Roger G, Lofaso F, Fauroux B (2005) Noninvasive positive pressure ventilation in infants with upper airway obstruction: comparison of continuous and bilevel positive pressure. Intensive Care Med 31:574–580PubMedCrossRef Essouri S, Nicot F, Clement A, Garabedian EN, Roger G, Lofaso F, Fauroux B (2005) Noninvasive positive pressure ventilation in infants with upper airway obstruction: comparison of continuous and bilevel positive pressure. Intensive Care Med 31:574–580PubMedCrossRef
129.
go back to reference Halbertsma FJ, Vaneker M, van der Hoeven JG (2007) Use of recruitment maneuvers during mechanical ventilation in pediatric and neonatal intensive care units in the Netherlands. Intensive Care Med 33:1673–1674PubMedCrossRef Halbertsma FJ, Vaneker M, van der Hoeven JG (2007) Use of recruitment maneuvers during mechanical ventilation in pediatric and neonatal intensive care units in the Netherlands. Intensive Care Med 33:1673–1674PubMedCrossRef
130.
go back to reference Halbertsma FJ, van der Hoeven JG (2005) Lung recruitment during mechanical positive pressure ventilation in the PICU: what can be learned from the literature? Anaesthesia 60:779–790PubMedCrossRef Halbertsma FJ, van der Hoeven JG (2005) Lung recruitment during mechanical positive pressure ventilation in the PICU: what can be learned from the literature? Anaesthesia 60:779–790PubMedCrossRef
131.
go back to reference Cruces P, Donoso A, Valenzuela J, Diaz F (2013) Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: a feasibility study. Pediatr Pulmonol 48:1135–1143PubMedCrossRef Cruces P, Donoso A, Valenzuela J, Diaz F (2013) Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: a feasibility study. Pediatr Pulmonol 48:1135–1143PubMedCrossRef
132.
go back to reference Scohy TV, Bikker IG, Hofland J, de Jong PL, Bogers AJ, Gommers D (2009) Alveolar recruitment strategy and PEEP improve oxygenation, dynamic compliance of respiratory system and end-expiratory lung volume in pediatric patients undergoing cardiac surgery for congenital heart disease. Paediatr Anaesth 19:1207–1212PubMedCrossRef Scohy TV, Bikker IG, Hofland J, de Jong PL, Bogers AJ, Gommers D (2009) Alveolar recruitment strategy and PEEP improve oxygenation, dynamic compliance of respiratory system and end-expiratory lung volume in pediatric patients undergoing cardiac surgery for congenital heart disease. Paediatr Anaesth 19:1207–1212PubMedCrossRef
133.
go back to reference Boriosi JP, Sapru A, Hanson JH, Asselin J, Gildengorin G, Newman V, Sabato K, Flori HR (2011) Efficacy and safety of lung recruitment in pediatric patients with acute lung injury. Pediatr Crit Care Med 12:431–436PubMedPubMedCentralCrossRef Boriosi JP, Sapru A, Hanson JH, Asselin J, Gildengorin G, Newman V, Sabato K, Flori HR (2011) Efficacy and safety of lung recruitment in pediatric patients with acute lung injury. Pediatr Crit Care Med 12:431–436PubMedPubMedCentralCrossRef
134.
go back to reference Kheir JN, Walsh BK, Smallwood CD, Rettig JS, Thompson JE, Gomez-Laberge C, Wolf GK, Arnold JH (2013) Comparison of 2 lung recruitment strategies in children with acute lung injury. Respir Care 58:1280–1290PubMedCrossRef Kheir JN, Walsh BK, Smallwood CD, Rettig JS, Thompson JE, Gomez-Laberge C, Wolf GK, Arnold JH (2013) Comparison of 2 lung recruitment strategies in children with acute lung injury. Respir Care 58:1280–1290PubMedCrossRef
135.
go back to reference Wolf GK, Gomez-Laberge C, Kheir JN, Zurakowski D, Walsh BK, Adler A, Arnold JH (2012) Reversal of dependent lung collapse predicts response to lung recruitment in children with early acute lung injury. Pediatr Crit Care Med 13:509–515PubMedCrossRef Wolf GK, Gomez-Laberge C, Kheir JN, Zurakowski D, Walsh BK, Adler A, Arnold JH (2012) Reversal of dependent lung collapse predicts response to lung recruitment in children with early acute lung injury. Pediatr Crit Care Med 13:509–515PubMedCrossRef
136.
go back to reference Boriosi JP, Cohen RA, Summers E, Sapru A, Hanson JH, Gildengorin G, Newman V, Flori HR (2012) Lung aeration changes after lung recruitment in children with acute lung injury: a feasibility study. Pediatr Pulmonol 47:771–779PubMedPubMedCentralCrossRef Boriosi JP, Cohen RA, Summers E, Sapru A, Hanson JH, Gildengorin G, Newman V, Flori HR (2012) Lung aeration changes after lung recruitment in children with acute lung injury: a feasibility study. Pediatr Pulmonol 47:771–779PubMedPubMedCentralCrossRef
137.
go back to reference Kaditis AG, Motoyama EK, Zin W, Maekawa N, Nishio I, Imai T, Milic-Emili J (2008) The effect of lung expansion and positive end-expiratory pressure on respiratory mechanics in anesthetized children. Anesth Analg 106:775–785PubMedCrossRef Kaditis AG, Motoyama EK, Zin W, Maekawa N, Nishio I, Imai T, Milic-Emili J (2008) The effect of lung expansion and positive end-expiratory pressure on respiratory mechanics in anesthetized children. Anesth Analg 106:775–785PubMedCrossRef
138.
go back to reference Duff JP, Rosychuk RJ, Joffe AR (2007) The safety and efficacy of sustained inflations as a lung recruitment maneuver in pediatric intensive care unit patients. Intensive Care Med 33:1778–1786PubMedCrossRef Duff JP, Rosychuk RJ, Joffe AR (2007) The safety and efficacy of sustained inflations as a lung recruitment maneuver in pediatric intensive care unit patients. Intensive Care Med 33:1778–1786PubMedCrossRef
139.
go back to reference Nacoti M, Spagnolli E, Bonanomi E, Barbanti C, Cereda M, Fumagalli R (2012) Sigh improves gas exchange and respiratory mechanics in children undergoing pressure support after major surgery. Minerva Anesthesiol 78:920–929 Nacoti M, Spagnolli E, Bonanomi E, Barbanti C, Cereda M, Fumagalli R (2012) Sigh improves gas exchange and respiratory mechanics in children undergoing pressure support after major surgery. Minerva Anesthesiol 78:920–929
140.
go back to reference Morrow B, Futter M, Argent A (2007) A recruitment manoeuvre performed after endotracheal suction does not increase dynamic compliance in ventilated paediatric patients: a randomised controlled trial. Aust J Physiother 53:163–169PubMedCrossRef Morrow B, Futter M, Argent A (2007) A recruitment manoeuvre performed after endotracheal suction does not increase dynamic compliance in ventilated paediatric patients: a randomised controlled trial. Aust J Physiother 53:163–169PubMedCrossRef
141.
go back to reference Gregory GA (1994) Pediatric anesthesia. Churchill Livingstone, New York Gregory GA (1994) Pediatric anesthesia. Churchill Livingstone, New York
142.
go back to reference Mau MK, Yamasato KS, Yamamoto LG (2005) Normal oxygen saturation values in pediatric patients. Hawaii Med J 64(42):44–45 Mau MK, Yamasato KS, Yamamoto LG (2005) Normal oxygen saturation values in pediatric patients. Hawaii Med J 64(42):44–45
143.
go back to reference Vengsarkar AS, Swan HJ (1964) Variations in oxygen saturation of arterial blood in infants and children with congenital heart disease. Am J Cardiol 14:622–627PubMedCrossRef Vengsarkar AS, Swan HJ (1964) Variations in oxygen saturation of arterial blood in infants and children with congenital heart disease. Am J Cardiol 14:622–627PubMedCrossRef
144.
go back to reference Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thebaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary CCP, Resuscitation, Council on Clinical C, Council on Cardiovascular Disease in the Y, Council on Cardiovascular R, Intervention, Council on Cardiovascular S, Anesthesia, the American Thoracic S (2015) pediatric pulmonary hypertension: guidelines From the American Heart Association and American Thoracic Society. Circulation 132:2037–2099PubMedCrossRef Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thebaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary CCP, Resuscitation, Council on Clinical C, Council on Cardiovascular Disease in the Y, Council on Cardiovascular R, Intervention, Council on Cardiovascular S, Anesthesia, the American Thoracic S (2015) pediatric pulmonary hypertension: guidelines From the American Heart Association and American Thoracic Society. Circulation 132:2037–2099PubMedCrossRef
145.
go back to reference Jenkinson SG (1993) Oxygen toxicity. N Horiz 1:504–511 Jenkinson SG (1993) Oxygen toxicity. N Horiz 1:504–511
146.
go back to reference Pannu SR (2016) Too much oxygen: hyperoxia and oxygen management in mechanically ventilated patients. Sem Respir Crit Care Med 37:16–22CrossRef Pannu SR (2016) Too much oxygen: hyperoxia and oxygen management in mechanically ventilated patients. Sem Respir Crit Care Med 37:16–22CrossRef
147.
go back to reference Abdelsalam M, Cheifetz IM (2010) Goal-directed therapy for severely hypoxic patients with acute respiratory distress syndrome: permissive hypoxemia. Respir Care 55:1483–1490PubMed Abdelsalam M, Cheifetz IM (2010) Goal-directed therapy for severely hypoxic patients with acute respiratory distress syndrome: permissive hypoxemia. Respir Care 55:1483–1490PubMed
148.
go back to reference Neto AS, Simonis FD, Barbas CS, Biehl M, Determann RM, Elmer J, Friedman G, Gajic O, Goldstein JN, Linko R, Pinheiro de Oliveira R, Sundar S, Talmor D, Wolthuis EK, Gama de Abreu M, Pelosi P, Schultz MJ, Investigators PRVN (2015) Lung-protective ventilation with low tidal volumes and the occurrence of pulmonary complications in patients without acute respiratory distress syndrome: a systematic review and individual patient data analysis. Crit Care Med 43:2155–2163PubMedCrossRef Neto AS, Simonis FD, Barbas CS, Biehl M, Determann RM, Elmer J, Friedman G, Gajic O, Goldstein JN, Linko R, Pinheiro de Oliveira R, Sundar S, Talmor D, Wolthuis EK, Gama de Abreu M, Pelosi P, Schultz MJ, Investigators PRVN (2015) Lung-protective ventilation with low tidal volumes and the occurrence of pulmonary complications in patients without acute respiratory distress syndrome: a systematic review and individual patient data analysis. Crit Care Med 43:2155–2163PubMedCrossRef
149.
go back to reference Laffey JG, O’Croinin D, McLoughlin P, Kavanagh BP (2004) Permissive hypercapnia–role in protective lung ventilatory strategies. Intensive Care Med 30:347–356PubMedCrossRef Laffey JG, O’Croinin D, McLoughlin P, Kavanagh BP (2004) Permissive hypercapnia–role in protective lung ventilatory strategies. Intensive Care Med 30:347–356PubMedCrossRef
150.
go back to reference Goldstein B, Shannon DC, Todres ID (1990) Supercarbia in children: clinical course and outcome. Crit Care Med 18:166–168PubMedCrossRef Goldstein B, Shannon DC, Todres ID (1990) Supercarbia in children: clinical course and outcome. Crit Care Med 18:166–168PubMedCrossRef
151.
go back to reference Curley MA, Fackler JC (1998) Weaning from mechanical ventilation: patterns in young children recovering from acute hypoxemic respiratory failure. Am J Crit Care 7:335–345PubMed Curley MA, Fackler JC (1998) Weaning from mechanical ventilation: patterns in young children recovering from acute hypoxemic respiratory failure. Am J Crit Care 7:335–345PubMed
152.
go back to reference Newth CJ, Venkataraman S, Willson DF, Meert KL, Harrison R, Dean JM, Pollack M, Zimmerman J, Anand KJ, Carcillo JA, Nicholson CE (2009) Weaning and extubation readiness in pediatric patients. Pediatr Crit Care Med 10:1–11PubMedPubMedCentralCrossRef Newth CJ, Venkataraman S, Willson DF, Meert KL, Harrison R, Dean JM, Pollack M, Zimmerman J, Anand KJ, Carcillo JA, Nicholson CE (2009) Weaning and extubation readiness in pediatric patients. Pediatr Crit Care Med 10:1–11PubMedPubMedCentralCrossRef
153.
go back to reference Foronda FK, Troster EJ, Farias JA, Barbas CS, Ferraro AA, Faria LS, Bousso A, Panico FF, Delgado AF (2011) The impact of daily evaluation and spontaneous breathing test on the duration of pediatric mechanical ventilation: a randomized controlled trial. Crit Care Med 39:2526–2533PubMedCrossRef Foronda FK, Troster EJ, Farias JA, Barbas CS, Ferraro AA, Faria LS, Bousso A, Panico FF, Delgado AF (2011) The impact of daily evaluation and spontaneous breathing test on the duration of pediatric mechanical ventilation: a randomized controlled trial. Crit Care Med 39:2526–2533PubMedCrossRef
154.
go back to reference Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH, Pediatric Acute Lung I, Sepsis Investigators N (2002) Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. JAMA 288:2561–2568PubMedCrossRef Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH, Pediatric Acute Lung I, Sepsis Investigators N (2002) Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. JAMA 288:2561–2568PubMedCrossRef
155.
go back to reference Schultz TR, Lin RJ, Watzman HM, Durning SM, Hales R, Woodson A, Francis B, Tyler L, Napoli L, Godinez RI (2001) Weaning children from mechanical ventilation: a prospective randomized trial of protocol-directed versus physician-directed weaning. Respir Care 46:772–782PubMed Schultz TR, Lin RJ, Watzman HM, Durning SM, Hales R, Woodson A, Francis B, Tyler L, Napoli L, Godinez RI (2001) Weaning children from mechanical ventilation: a prospective randomized trial of protocol-directed versus physician-directed weaning. Respir Care 46:772–782PubMed
156.
go back to reference Blackwood B, Murray M, Chisakuta A, Cardwell CR, O’Halloran P (2013) Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in critically ill paediatric patients. Cochrane Database Syst Rev: CD009082 Blackwood B, Murray M, Chisakuta A, Cardwell CR, O’Halloran P (2013) Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in critically ill paediatric patients. Cochrane Database Syst Rev: CD009082
157.
go back to reference Jouvet P, Eddington A, Payen V, Bordessoule A, Emeriaud G, Gasco RL, Wysocki M (2012) A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase. Crit Care 16:R85PubMedPubMedCentralCrossRef Jouvet P, Eddington A, Payen V, Bordessoule A, Emeriaud G, Gasco RL, Wysocki M (2012) A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase. Crit Care 16:R85PubMedPubMedCentralCrossRef
158.
go back to reference Jouvet PA, Payen V, Gauvin F, Emeriaud G, Lacroix J (2013) Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med 39:919–925PubMedCrossRef Jouvet PA, Payen V, Gauvin F, Emeriaud G, Lacroix J (2013) Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med 39:919–925PubMedCrossRef
159.
go back to reference Rose L, Schultz MJ, Cardwell CR, Jouvet P, McAuley DF, Blackwood B (2015) Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta- analysis. Crit Care 19:48PubMedPubMedCentralCrossRef Rose L, Schultz MJ, Cardwell CR, Jouvet P, McAuley DF, Blackwood B (2015) Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta- analysis. Crit Care 19:48PubMedPubMedCentralCrossRef
160.
go back to reference Jouvet P, Farges C, Hatzakis G, Monir A, Lesage F, Dupic L, Brochard L, Hubert P (2007) Weaning children from mechanical ventilation with a computer-driven system (closed-loop protocol): a pilot study. Pediatr Crit Care Med 8:425–432PubMedCrossRef Jouvet P, Farges C, Hatzakis G, Monir A, Lesage F, Dupic L, Brochard L, Hubert P (2007) Weaning children from mechanical ventilation with a computer-driven system (closed-loop protocol): a pilot study. Pediatr Crit Care Med 8:425–432PubMedCrossRef
161.
go back to reference Rushforth K (2005) A randomised controlled trial of weaning from mechanical ventilation in paediatric intensive care (PIC). Methodological and practical issues. Intensive Crit Care Nurs 21:76–86PubMedCrossRef Rushforth K (2005) A randomised controlled trial of weaning from mechanical ventilation in paediatric intensive care (PIC). Methodological and practical issues. Intensive Crit Care Nurs 21:76–86PubMedCrossRef
162.
go back to reference Suominen PK, Tuominen NA, Salminen JT, Korpela RE, Klockars JG, Taivainen TR, Meretoja OA (2007) The air-leak test is not a good predictor of postextubation adverse events in children undergoing cardiac surgery. J Ccardiothorac Vasc Anesthesia 21:197–202CrossRef Suominen PK, Tuominen NA, Salminen JT, Korpela RE, Klockars JG, Taivainen TR, Meretoja OA (2007) The air-leak test is not a good predictor of postextubation adverse events in children undergoing cardiac surgery. J Ccardiothorac Vasc Anesthesia 21:197–202CrossRef
163.
go back to reference Takeuchi M, Imanaka H, Miyano H, Kumon K, Nishimura M (2000) Effect of patient-triggered ventilation on respiratory workload in infants after cardiac surgery. Anesthesiology 93:1238–1244 (discussion 1235A) PubMedCrossRef Takeuchi M, Imanaka H, Miyano H, Kumon K, Nishimura M (2000) Effect of patient-triggered ventilation on respiratory workload in infants after cardiac surgery. Anesthesiology 93:1238–1244 (discussion 1235A) PubMedCrossRef
164.
go back to reference Wolf GK, Walsh BK, Green ML, Arnold JH (2011) Electrical activity of the diaphragm during extubation readiness testing in critically ill children. Pediatr Crit Care Med 12:e220–e224PubMedCrossRef Wolf GK, Walsh BK, Green ML, Arnold JH (2011) Electrical activity of the diaphragm during extubation readiness testing in critically ill children. Pediatr Crit Care Med 12:e220–e224PubMedCrossRef
165.
go back to reference Withington DE, Davis GM, Vallinis P, Del Sonno P, Bevan JC (1998) Respiratory function in children during recovery from neuromuscular blockade. Paediatr Anaesth 8:41–47PubMedCrossRef Withington DE, Davis GM, Vallinis P, Del Sonno P, Bevan JC (1998) Respiratory function in children during recovery from neuromuscular blockade. Paediatr Anaesth 8:41–47PubMedCrossRef
166.
go back to reference Harikumar G, Egberongbe Y, Nadel S, Wheatley E, Moxham J, Greenough A, Rafferty GF (2009) Tension-time index as a predictor of extubation outcome in ventilated children. Am J Respir Crit Care Med 180:982–988PubMedPubMedCentralCrossRef Harikumar G, Egberongbe Y, Nadel S, Wheatley E, Moxham J, Greenough A, Rafferty GF (2009) Tension-time index as a predictor of extubation outcome in ventilated children. Am J Respir Crit Care Med 180:982–988PubMedPubMedCentralCrossRef
167.
go back to reference Mohr AM, Rutherford EJ, Cairns BA, Boysen PG (2001) The role of dead space ventilation in predicting outcome of successful weaning from mechanical ventilation. J Trauma 51:843–848PubMedCrossRef Mohr AM, Rutherford EJ, Cairns BA, Boysen PG (2001) The role of dead space ventilation in predicting outcome of successful weaning from mechanical ventilation. J Trauma 51:843–848PubMedCrossRef
168.
go back to reference Noizet O, Leclerc F, Sadik A, Grandbastien B, Riou Y, Dorkenoo A, Fourier C, Cremer R, Leteurtre S (2005) Does taking endurance into account improve the prediction of weaning outcome in mechanically ventilated children? Crit Care 9:R798–R807PubMedPubMedCentralCrossRef Noizet O, Leclerc F, Sadik A, Grandbastien B, Riou Y, Dorkenoo A, Fourier C, Cremer R, Leteurtre S (2005) Does taking endurance into account improve the prediction of weaning outcome in mechanically ventilated children? Crit Care 9:R798–R807PubMedPubMedCentralCrossRef
169.
go back to reference Farias JA, Alia I, Esteban A, Golubicki AN, Olazarri FA (1998) Weaning from mechanical ventilation in pediatric intensive care patients. Intensive Care Med 24:1070–1075PubMedCrossRef Farias JA, Alia I, Esteban A, Golubicki AN, Olazarri FA (1998) Weaning from mechanical ventilation in pediatric intensive care patients. Intensive Care Med 24:1070–1075PubMedCrossRef
170.
go back to reference Gaies M, Tabbutt S, Schwartz SM, Bird GL, Alten JA, Shekerdemian LS, Klugman D, Thiagarajan RR, Gaynor JW, Jacobs JP, Nicolson SC, Donohue JE, Yu S, Pasquali SK, Cooper DS (2015) Clinical epidemiology of extubation failure in the pediatric cardiac ICU: a report from the Pediatric Cardiac Critical Care Consortium. Pediatr Crit Care Med 16:837–845PubMedPubMedCentralCrossRef Gaies M, Tabbutt S, Schwartz SM, Bird GL, Alten JA, Shekerdemian LS, Klugman D, Thiagarajan RR, Gaynor JW, Jacobs JP, Nicolson SC, Donohue JE, Yu S, Pasquali SK, Cooper DS (2015) Clinical epidemiology of extubation failure in the pediatric cardiac ICU: a report from the Pediatric Cardiac Critical Care Consortium. Pediatr Crit Care Med 16:837–845PubMedPubMedCentralCrossRef
171.
go back to reference Willis BC, Graham AS, Yoon E, Wetzel RC, Newth CJ (2005) Pressure-rate products and phase angles in children on minimal support ventilation and after extubation. Intensive Care Med 31:1700–1705PubMedCrossRef Willis BC, Graham AS, Yoon E, Wetzel RC, Newth CJ (2005) Pressure-rate products and phase angles in children on minimal support ventilation and after extubation. Intensive Care Med 31:1700–1705PubMedCrossRef
172.
go back to reference Wratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM (2008) The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med 9:490–496PubMedPubMedCentralCrossRef Wratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM (2008) The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med 9:490–496PubMedPubMedCentralCrossRef
173.
go back to reference Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O’Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH, Pediatric Acute Lung I, Sepsis Investigators N (2005) Cumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. Pediatr Crit Care Med 6:642–647PubMedCrossRef Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O’Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH, Pediatric Acute Lung I, Sepsis Investigators N (2005) Cumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. Pediatr Crit Care Med 6:642–647PubMedCrossRef
174.
go back to reference Tobin MJ (2012) Extubation and the myth of “minimal ventilator settings”. Am J Respir Crit Care Med 185:349–350PubMedCrossRef Tobin MJ (2012) Extubation and the myth of “minimal ventilator settings”. Am J Respir Crit Care Med 185:349–350PubMedCrossRef
175.
go back to reference Manczur T, Greenough A, Nicholson GP, Rafferty GF (2000) Resistance of pediatric and neonatal endotracheal tubes: influence of flow rate, size, and shape. Crit Care Med 28:1595–1598PubMedCrossRef Manczur T, Greenough A, Nicholson GP, Rafferty GF (2000) Resistance of pediatric and neonatal endotracheal tubes: influence of flow rate, size, and shape. Crit Care Med 28:1595–1598PubMedCrossRef
176.
go back to reference Khemani RG, Hotz J, Morzov R, Flink RC, Kamerkar A, LaFortune M, Rafferty GF, Ross PA, Newth CJ (2016) Pediatric extubation readiness tests should not use pressure support. Intensive Care Med 42:1214–1222PubMedCrossRef Khemani RG, Hotz J, Morzov R, Flink RC, Kamerkar A, LaFortune M, Rafferty GF, Ross PA, Newth CJ (2016) Pediatric extubation readiness tests should not use pressure support. Intensive Care Med 42:1214–1222PubMedCrossRef
177.
go back to reference Vianello A, Arcaro G, Braccioni F, Gallan F, Marchi MR, Chizio S, Zampieri D, Pegoraro E, Salvador V (2011) Prevention of extubation failure in high-risk patients with neuromuscular disease. J Crit Care 26:517–524PubMedCrossRef Vianello A, Arcaro G, Braccioni F, Gallan F, Marchi MR, Chizio S, Zampieri D, Pegoraro E, Salvador V (2011) Prevention of extubation failure in high-risk patients with neuromuscular disease. J Crit Care 26:517–524PubMedCrossRef
178.
go back to reference Bach JR, Goncalves MR, Hamdani I, Winck JC (2010) Extubation of patients with neuromuscular weakness: a new management paradigm. Chest 137:1033–1039PubMedCrossRef Bach JR, Goncalves MR, Hamdani I, Winck JC (2010) Extubation of patients with neuromuscular weakness: a new management paradigm. Chest 137:1033–1039PubMedCrossRef
179.
go back to reference Hull J, Aniapravan R, Chan E, Chatwin M, Forton J, Gallagher J, Gibson N, Gordon J, Hughes I, McCulloch R, Russell RR, Simonds A (2012) British Thoracic Society guideline for respiratory management of children with neuromuscular weakness. Thorax 67(Suppl 1):i1–i40PubMedCrossRef Hull J, Aniapravan R, Chan E, Chatwin M, Forton J, Gallagher J, Gibson N, Gordon J, Hughes I, McCulloch R, Russell RR, Simonds A (2012) British Thoracic Society guideline for respiratory management of children with neuromuscular weakness. Thorax 67(Suppl 1):i1–i40PubMedCrossRef
180.
go back to reference Racca F, Mongini T, Wolfler A, Vianello A, Cutrera R, Del Sorbo L, Capello EC, Gregoretti C, Massa R, De Luca D, Conti G, Tegazzin V, Toscano A, Ranieri VM (2013) Recommendations for anesthesia and perioperative management of patients with neuromuscular disorders. Minerva Anestesiol 79:419–433PubMed Racca F, Mongini T, Wolfler A, Vianello A, Cutrera R, Del Sorbo L, Capello EC, Gregoretti C, Massa R, De Luca D, Conti G, Tegazzin V, Toscano A, Ranieri VM (2013) Recommendations for anesthesia and perioperative management of patients with neuromuscular disorders. Minerva Anestesiol 79:419–433PubMed
181.
go back to reference Bissonnette B, Sessler DI, LaFlamme P (1989) Passive and active inspired gas humidification in infants and children. Anesthesiology 71:350–354PubMedCrossRef Bissonnette B, Sessler DI, LaFlamme P (1989) Passive and active inspired gas humidification in infants and children. Anesthesiology 71:350–354PubMedCrossRef
182.
go back to reference Bissonnette B, Sessler DI (1989) Passive or active inspired gas humidification increases thermal steady-state temperatures in anesthetized infants. Anesth Analg 69:783–787PubMed Bissonnette B, Sessler DI (1989) Passive or active inspired gas humidification increases thermal steady-state temperatures in anesthetized infants. Anesth Analg 69:783–787PubMed
183.
go back to reference Kelly M, Gillies D, Todd DA, Lockwood C (2010) Heated humidification versus heat and moisture exchangers for ventilated adults and children. Cochrane Database Syst Rev: CD004711 Kelly M, Gillies D, Todd DA, Lockwood C (2010) Heated humidification versus heat and moisture exchangers for ventilated adults and children. Cochrane Database Syst Rev: CD004711
184.
go back to reference Lellouche F, Taille S, Lefrancois F, Deye N, Maggiore SM, Jouvet P, Ricard JD, Fumagalli B, Brochard L, Groupe de travail sur les Respirateurs de l A-H (2009) Humidification performance of 48 passive airway humidifiers: comparison with manufacturer data. Chest 135:276–286PubMedCrossRef Lellouche F, Taille S, Lefrancois F, Deye N, Maggiore SM, Jouvet P, Ricard JD, Fumagalli B, Brochard L, Groupe de travail sur les Respirateurs de l A-H (2009) Humidification performance of 48 passive airway humidifiers: comparison with manufacturer data. Chest 135:276–286PubMedCrossRef
185.
go back to reference Morrow B, Futter M, Argent A (2006) Effect of endotracheal suction on lung dynamics in mechanically-ventilated paediatric patients. Aust J Physiother 52:121–126PubMedCrossRef Morrow B, Futter M, Argent A (2006) Effect of endotracheal suction on lung dynamics in mechanically-ventilated paediatric patients. Aust J Physiother 52:121–126PubMedCrossRef
186.
go back to reference Avena MJ, de Carvalho WB, Beppu OS (2003) Evaluation of oxygenation, ventilation and respiratory mechanics before and after endotracheal suction in mechanically ventilated children. Rev Assoc Med Bras 49:156–161PubMedCrossRef Avena MJ, de Carvalho WB, Beppu OS (2003) Evaluation of oxygenation, ventilation and respiratory mechanics before and after endotracheal suction in mechanically ventilated children. Rev Assoc Med Bras 49:156–161PubMedCrossRef
187.
go back to reference Choong K, Chatrkaw P, Frndova H, Cox PN (2003) Comparison of loss in lung volume with open versus in-line catheter endotracheal suctioning. Pediatr Crit Care Med 4:69–73PubMedCrossRef Choong K, Chatrkaw P, Frndova H, Cox PN (2003) Comparison of loss in lung volume with open versus in-line catheter endotracheal suctioning. Pediatr Crit Care Med 4:69–73PubMedCrossRef
188.
go back to reference Copnell B, Fergusson D (1995) Endotracheal suctioning: time-worn ritual or timely intervention? Am J Crit Care 4:100–105PubMed Copnell B, Fergusson D (1995) Endotracheal suctioning: time-worn ritual or timely intervention? Am J Crit Care 4:100–105PubMed
189.
go back to reference Gilbert M (1999) Assessing the need for endotracheal suction. Paediatr Nurs 11:14–17PubMed Gilbert M (1999) Assessing the need for endotracheal suction. Paediatr Nurs 11:14–17PubMed
190.
go back to reference Krause MF, Hoehn T (2000) Chest physiotherapy in mechanically ventilated children: a review. Crit Care Med 28:1648–1651PubMedCrossRef Krause MF, Hoehn T (2000) Chest physiotherapy in mechanically ventilated children: a review. Crit Care Med 28:1648–1651PubMedCrossRef
191.
go back to reference Hawkins E, Jones A (2015) What is the role of the physiotherapist in paediatric intensive care units? A systematic review of the evidence for respiratory and rehabilitation interventions for mechanically ventilated patients. Physiotherapy 101:303–309PubMedCrossRef Hawkins E, Jones A (2015) What is the role of the physiotherapist in paediatric intensive care units? A systematic review of the evidence for respiratory and rehabilitation interventions for mechanically ventilated patients. Physiotherapy 101:303–309PubMedCrossRef
192.
go back to reference Vianello A, Corrado A, Arcaro G, Gallan F, Ori C, Minuzzo M, Bevilacqua M (2005) Mechanical insufflation–exsufflation improves outcomes for neuromuscular disease patients with respiratory tract infections. Am J Phys Med Rehabi 84:83–88 (discussion 89–91) CrossRef Vianello A, Corrado A, Arcaro G, Gallan F, Ori C, Minuzzo M, Bevilacqua M (2005) Mechanical insufflation–exsufflation improves outcomes for neuromuscular disease patients with respiratory tract infections. Am J Phys Med Rehabi 84:83–88 (discussion 89–91) CrossRef
193.
go back to reference Miske LJ, Hickey EM, Kolb SM, Weiner DJ, Panitch HB (2004) Use of the mechanical in-exsufflator in pediatric patients with neuromuscular disease and impaired cough. Chest 125:1406–1412PubMedCrossRef Miske LJ, Hickey EM, Kolb SM, Weiner DJ, Panitch HB (2004) Use of the mechanical in-exsufflator in pediatric patients with neuromuscular disease and impaired cough. Chest 125:1406–1412PubMedCrossRef
194.
go back to reference Fauroux B, Guillemot N, Aubertin G, Nathan N, Labit A, Clement A, Lofaso F (2008) Physiologic benefits of mechanical insufflation-exsufflation in children with neuromuscular diseases. Chest 133:161–168PubMedCrossRef Fauroux B, Guillemot N, Aubertin G, Nathan N, Labit A, Clement A, Lofaso F (2008) Physiologic benefits of mechanical insufflation-exsufflation in children with neuromuscular diseases. Chest 133:161–168PubMedCrossRef
195.
go back to reference Chatwin M, Ross E, Hart N, Nickol AH, Polkey MI, Simonds AK (2003) Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness. Eur Respir J 21:502–508PubMedCrossRef Chatwin M, Ross E, Hart N, Nickol AH, Polkey MI, Simonds AK (2003) Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness. Eur Respir J 21:502–508PubMedCrossRef
196.
go back to reference Racca F, Del Sorbo L, Mongini T, Vianello A, Ranieri VM (2010) Respiratory management of acute respiratory failure in neuromuscular diseases. Minerva Anestesiol 76:51–62PubMed Racca F, Del Sorbo L, Mongini T, Vianello A, Ranieri VM (2010) Respiratory management of acute respiratory failure in neuromuscular diseases. Minerva Anestesiol 76:51–62PubMed
197.
go back to reference Newth CJ, Rachman B, Patel N, Hammer J (2004) The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care. J Pediatr 144:333–337PubMedCrossRef Newth CJ, Rachman B, Patel N, Hammer J (2004) The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care. J Pediatr 144:333–337PubMedCrossRef
198.
go back to reference Weiss M, Dullenkopf A, Fischer JE, Keller C, Gerber AC, European Paediatric Endotracheal Intubation Study G (2009) Prospective randomized controlled multi- centre trial of cuffed or uncuffed endotracheal tubes in small children. Br J Anaesth 103:867–873PubMedCrossRef Weiss M, Dullenkopf A, Fischer JE, Keller C, Gerber AC, European Paediatric Endotracheal Intubation Study G (2009) Prospective randomized controlled multi- centre trial of cuffed or uncuffed endotracheal tubes in small children. Br J Anaesth 103:867–873PubMedCrossRef
199.
go back to reference Rabello L, Conceicao C, Ebecken K, Lisboa T, Bozza FA, Soares M, Povoa P, Salluh JI (2015) Management of severe community-acquired pneumonia in Brazil: a secondary analysis of an international survey. Rev Bras Ter Intensiva 27:57–63PubMedPubMedCentralCrossRef Rabello L, Conceicao C, Ebecken K, Lisboa T, Bozza FA, Soares M, Povoa P, Salluh JI (2015) Management of severe community-acquired pneumonia in Brazil: a secondary analysis of an international survey. Rev Bras Ter Intensiva 27:57–63PubMedPubMedCentralCrossRef
200.
go back to reference Pearsall MF, Feldman JM (2014) When does apparatus dead space matter for the pediatric patient? Anesth Analg 118:776–780PubMedCrossRef Pearsall MF, Feldman JM (2014) When does apparatus dead space matter for the pediatric patient? Anesth Analg 118:776–780PubMedCrossRef
201.
go back to reference Lujan M, Sogo A, Grimau C, Pomares X, Blanch L, Monso E (2015) Influence of dynamic leaks in volume-targeted pressure support noninvasive ventilation: a bench study. Respir Care 60:191–200PubMedCrossRef Lujan M, Sogo A, Grimau C, Pomares X, Blanch L, Monso E (2015) Influence of dynamic leaks in volume-targeted pressure support noninvasive ventilation: a bench study. Respir Care 60:191–200PubMedCrossRef
202.
go back to reference Fauroux B, Leroux K, Desmarais G, Isabey D, Clement A, Lofaso F, Louis B (2008) Performance of ventilators for noninvasive positive-pressure ventilation in children. Eur Respir J 31:1300–1307PubMedCrossRef Fauroux B, Leroux K, Desmarais G, Isabey D, Clement A, Lofaso F, Louis B (2008) Performance of ventilators for noninvasive positive-pressure ventilation in children. Eur Respir J 31:1300–1307PubMedCrossRef
203.
go back to reference Hussey SG, Ryan CA, Murphy BP (2004) Comparison of three manual ventilation devices using an intubated mannequin. Arch Dis Child Fetal Neonatal Ed 89:F490–F493PubMedPubMedCentralCrossRef Hussey SG, Ryan CA, Murphy BP (2004) Comparison of three manual ventilation devices using an intubated mannequin. Arch Dis Child Fetal Neonatal Ed 89:F490–F493PubMedPubMedCentralCrossRef
204.
go back to reference Boussaid G, Lofaso F, Santos DB, Vaugier I, Pottier S, Prigent H, Bahrami S, Orlikowski D (2016) Impact of invasive ventilation on survival when non-invasive ventilation is ineffective in patients with Duchenne muscular dystrophy: a prospective cohort. Respir Med 115:26–32PubMedCrossRef Boussaid G, Lofaso F, Santos DB, Vaugier I, Pottier S, Prigent H, Bahrami S, Orlikowski D (2016) Impact of invasive ventilation on survival when non-invasive ventilation is ineffective in patients with Duchenne muscular dystrophy: a prospective cohort. Respir Med 115:26–32PubMedCrossRef
205.
go back to reference Rul B, Carnevale F, Estournet B, Rudler M, Herve C (2012) Tracheotomy and children with spinal muscular atrophy type 1: ethical considerations in the French context. Nurs Ethics 19:408–418PubMedCrossRef Rul B, Carnevale F, Estournet B, Rudler M, Herve C (2012) Tracheotomy and children with spinal muscular atrophy type 1: ethical considerations in the French context. Nurs Ethics 19:408–418PubMedCrossRef
206.
go back to reference Benson RC, Hardy KA, Gildengorin G, Hsia D (2012) International survey of physician recommendation for tracheostomy for spinal muscular atrophy type I. Pediatr Pulmonol 47:606–611PubMedCrossRef Benson RC, Hardy KA, Gildengorin G, Hsia D (2012) International survey of physician recommendation for tracheostomy for spinal muscular atrophy type I. Pediatr Pulmonol 47:606–611PubMedCrossRef
207.
go back to reference Simonds AK (2007) Respiratory support for the severely handicapped child with neuromuscular disease: ethics and practicality. Sem Respir Crit Care Med 28:342–354CrossRef Simonds AK (2007) Respiratory support for the severely handicapped child with neuromuscular disease: ethics and practicality. Sem Respir Crit Care Med 28:342–354CrossRef
208.
go back to reference Bush A (2006) Spinal muscular atrophy with respiratory disease (SMARD): an ethical dilemma. Intensive Care Med 32:1691–1693PubMedCrossRef Bush A (2006) Spinal muscular atrophy with respiratory disease (SMARD): an ethical dilemma. Intensive Care Med 32:1691–1693PubMedCrossRef
209.
go back to reference Yamaguchi M, Suzuki M (2013) Independent living with Duchenne muscular dystrophy and home mechanical ventilation in areas of Japan with insufficient national welfare services. Int J Qual Stud Health Well-being 8:20914PubMedCrossRef Yamaguchi M, Suzuki M (2013) Independent living with Duchenne muscular dystrophy and home mechanical ventilation in areas of Japan with insufficient national welfare services. Int J Qual Stud Health Well-being 8:20914PubMedCrossRef
210.
go back to reference Rimensberger PC, Heulitt MJ, Meliones J, Pons M, Bronicki RA (2011) Mechanical ventilation in the pediatric cardiac intensive care unit: the essentials. World J Pediatr Congenit Heart Surg 2:609–619PubMedCrossRef Rimensberger PC, Heulitt MJ, Meliones J, Pons M, Bronicki RA (2011) Mechanical ventilation in the pediatric cardiac intensive care unit: the essentials. World J Pediatr Congenit Heart Surg 2:609–619PubMedCrossRef
211.
go back to reference Bronicki RA, Penny DJ, Anas NG, Fuhrman B (2016) Cardiopulmonary Interactions. Pediatr Crit Care Med 17:S182–S193PubMedCrossRef Bronicki RA, Penny DJ, Anas NG, Fuhrman B (2016) Cardiopulmonary Interactions. Pediatr Crit Care Med 17:S182–S193PubMedCrossRef
213.
go back to reference Bronicki RA, Herrera M, Mink RB, Domico M, Tucker D, Chang AC, Anas NG (2010) Hemodynamics and cerebral oxygenation following repair of tetralogy of Fallot: the effects of converting from positive pressure ventilation to spontaneous breathing. Congen Heart Dis 5:416–421CrossRef Bronicki RA, Herrera M, Mink RB, Domico M, Tucker D, Chang AC, Anas NG (2010) Hemodynamics and cerebral oxygenation following repair of tetralogy of Fallot: the effects of converting from positive pressure ventilation to spontaneous breathing. Congen Heart Dis 5:416–421CrossRef
214.
go back to reference Jenkins J, Lynn A, Edmonds J, Barker G (1985) Effects of mechanical ventilation on cardiopulmonary function in children after open-heart surgery. Crit Care Med 13:77–80PubMedCrossRef Jenkins J, Lynn A, Edmonds J, Barker G (1985) Effects of mechanical ventilation on cardiopulmonary function in children after open-heart surgery. Crit Care Med 13:77–80PubMedCrossRef
215.
go back to reference Gregory GA, Edmunds LH Jr, Kitterman JA, Phibbs RH, Tooley WH (1975) Continuous positive airway pressure and pulmonary and circulatory function after cardiac surgery in infants less than three months of age. Anesthesiology 43:426–431PubMedCrossRef Gregory GA, Edmunds LH Jr, Kitterman JA, Phibbs RH, Tooley WH (1975) Continuous positive airway pressure and pulmonary and circulatory function after cardiac surgery in infants less than three months of age. Anesthesiology 43:426–431PubMedCrossRef
216.
go back to reference Colgan FJ, Stewart S (1979) PEEP and CPAP following open-heart surgery in infants and children. Anesthesiology 50:336–341PubMedCrossRef Colgan FJ, Stewart S (1979) PEEP and CPAP following open-heart surgery in infants and children. Anesthesiology 50:336–341PubMedCrossRef
217.
go back to reference Kardos A, Vereczkey G, Szentirmai C (2005) Haemodynamic changes during positive-pressure ventilation in children. Acta Anaesthesiol Scand 49:649–653PubMedCrossRef Kardos A, Vereczkey G, Szentirmai C (2005) Haemodynamic changes during positive-pressure ventilation in children. Acta Anaesthesiol Scand 49:649–653PubMedCrossRef
218.
go back to reference Levett JM, Culpepper WS, Lin CY, Arcilla RA, Replogle RL (1983) Cardiovascular responses to PEEP and CPAP following repair of complicated congenital heart defects. Ann Thorac Surg 36:411–416PubMedCrossRef Levett JM, Culpepper WS, Lin CY, Arcilla RA, Replogle RL (1983) Cardiovascular responses to PEEP and CPAP following repair of complicated congenital heart defects. Ann Thorac Surg 36:411–416PubMedCrossRef
219.
go back to reference Alexi-Meskhisvili VV, Falkowski GE, Nikoljuk AP, Popov SA (1985) Hemodynamic changes during mechanical ventilation in infants and small children after open heart surgery. Thorac Cardiovasc Surg 33:215–217PubMedCrossRef Alexi-Meskhisvili VV, Falkowski GE, Nikoljuk AP, Popov SA (1985) Hemodynamic changes during mechanical ventilation in infants and small children after open heart surgery. Thorac Cardiovasc Surg 33:215–217PubMedCrossRef
220.
go back to reference Vincent JL (2010) We should abandon randomized controlled trials in the intensive care unit. Crit Care Med 38:S534–S538PubMedCrossRef Vincent JL (2010) We should abandon randomized controlled trials in the intensive care unit. Crit Care Med 38:S534–S538PubMedCrossRef
221.
go back to reference Khemani RG, Newth CJ (2010) The design of future pediatric mechanical ventilation trials for acute lung injury. Am J Respir Crit Care Med 182:1465–1474PubMedPubMedCentralCrossRef Khemani RG, Newth CJ (2010) The design of future pediatric mechanical ventilation trials for acute lung injury. Am J Respir Crit Care Med 182:1465–1474PubMedPubMedCentralCrossRef
222.
Metadata
Title
Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC)
Authors
Martin C. J. Kneyber
Daniele de Luca
Edoardo Calderini
Pierre-Henri Jarreau
Etienne Javouhey
Jesus Lopez-Herce
Jürg Hammer
Duncan Macrae
Dick G. Markhorst
Alberto Medina
Marti Pons-Odena
Fabrizio Racca
Gerhard Wolf
Paolo Biban
Joe Brierley
Peter C. Rimensberger
on behalf of the section Respiratory Failure of the European Society for Paediatric and Neonatal Intensive Care
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 12/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-017-4920-z

Other articles of this Issue 12/2017

Intensive Care Medicine 12/2017 Go to the issue