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Published in: Current Fungal Infection Reports 1/2022

01-03-2022 | Voriconazole | Pediatric Fungal Infections (D. Corzo-Leon, Section Editor)

Central Nervous System Fungal Infections in Paediatric Patients

Authors: Deborah Palacios-Reyes, Ángeles Costta-Michuy, Tania M. Vargas-Vázquez, M. Vanessa Martínez-Astudillo, Rafael Oscar Santamaría Vásquez, Nancy E. Aguilar-Gómez, Astrid A. Hernandez-Soto, Sofia Fortes-Gutiérrez, Daniel Reyes-Gutierrez, Dania J. Juárez-Padilla, Silvia Fuentes-Soliz

Published in: Current Fungal Infection Reports | Issue 1/2022

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Abstract

Purpose of Review

The objective of this paper is to review the main paediatric populations at risk for IFI-CNS and the most frequent agents involved, focusing in the clinical/radiological and diagnostic features, as well as the recommended treatment.

Recent Findings

With new and improved diagnostic techniques, reports on CNS fungal infections in paediatricpatients have increased not only in those with recently discovered congenital immune defects but in immunocompetent childrenas well. Information regarding clinical and imaging findings has expanded to shed light on previously ignored diagnoses.

Summary

Apart from well-described and devastating IFI caused by Candida spp. and Aspergillus spp., other fungal agents are gaining importance not only in immunocompromised patients, but also in children with no identified risk factors, apart from environmental exposure.
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Metadata
Title
Central Nervous System Fungal Infections in Paediatric Patients
Authors
Deborah Palacios-Reyes
Ángeles Costta-Michuy
Tania M. Vargas-Vázquez
M. Vanessa Martínez-Astudillo
Rafael Oscar Santamaría Vásquez
Nancy E. Aguilar-Gómez
Astrid A. Hernandez-Soto
Sofia Fortes-Gutiérrez
Daniel Reyes-Gutierrez
Dania J. Juárez-Padilla
Silvia Fuentes-Soliz
Publication date
01-03-2022
Publisher
Springer US
Published in
Current Fungal Infection Reports / Issue 1/2022
Print ISSN: 1936-3761
Electronic ISSN: 1936-377X
DOI
https://doi.org/10.1007/s12281-021-00427-5
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