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Aspergillosis 

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  1. Open Access 01-12-2024 | Aspergillosis | OriginalPaper

    COVID-19 associated pulmonary aspergillosis in critically-ill patients: a prospective multicenter study in the era of Delta and Omicron variants

    The societal and individual consequences of pneumonia caused by respiratory viruses, notably due to influenza virus and SARS-CoV-2, are well established. Patients with severe pneumonia may develop acute respiratory failure and require admission to …

  2. 16-04-2024 | Invasive Aspergillosis | Online First

    Evaluation of the JF5-based Aspergillus galactomannoprotein lateral flow device for diagnosing invasive aspergillosis in cancer patients

    Invasive aspergillosis (IA) is a life-threatening infectious disease that affects individuals with compromised immune function [ 1 ]. Cancer patients, including those with hematologic malignancies and solid tumours, are often in a state of …

  3. Open Access 01-12-2024 | COVID-19 | Letter

    Covid-19-associated pulmonary aspergillosis in mechanically ventilated patients

  4. Open Access 01-12-2024 | COVID-19 | OriginalPaper

    Risk factors for COVID-19 associated pulmonary aspergillosis and outcomes in patients with acute respiratory failure in a respiratory sub-intensive care unit

    Invasive pulmonary aspergillosis (IPA) has been observed in association with respiratory viral illnesses, such as influenza, SARS-CoV-1, and MERS [ 1 – 3 ].

  5. 07-02-2024 | Influenza | OriginalPaper

    Comparison of influenza- and COVID-19-associated pulmonary aspergillosis in China

    Invasive pulmonary aspergillosis (IPA) is caused by Aspergillus species, which has been mainly described in immunocompromised patients, especially in severe and prolonged neutropenia, hematological malignancies, and solid organ transplantation [ 1 …

  6. 12-02-2024 | Amphotericin B | OriginalPaper

    Risk factors for short-term prognosis of end-stage liver disease complicated by invasive pulmonary aspergillosis

    End-stage liver disease (ESLD) is often life-threatening due to severe complications such as comorbid infection, hemorrhage, ascites, hepatic encephalopathy, and hepatorenal syndrome. The 28-d mortality rate of acute-on-chronic liver failure …

  7. Open Access 01-12-2024 | Invasive Aspergillosis | OriginalPaper

    Age difference of patients with and without invasive aspergillosis: a systematic review and meta-analysis

    Aspergillus spp. are among the most common causes of fungal infections in humans and can cause a variety of diseases in immunocompromised individuals and those with chronic lung disorders [ 1 ]. Invasive aspergillosis (IA) is estimated to affect …

  8. 16-11-2023 | Aspergillosis | OriginalPaper

    Osteomyelitis of Jaw Bone due to Aspergillosis in Post-COVID-19 Patients: An Observational Study

    The Corona virus disease or COVID-19 infection which has been officially declared a pandemic, has put an enormous strain on the healthcare sector worldwide. It has come to light that there is an increased number of cases of infectious diseases of …

  9. 06-02-2024 | Aspergillosis | Online First

    Lacrimal sac Aspergillosis Masquerading as Malignancy: A Rare Case Report

    Invasive fungal infections are uncommon in an immunocompetent host and pose a real diagnostic dilemma. As they have a propensity for locoregional destruction, clinic-radiological findings can mislead to a faulty diagnosis of a malignancy. Here we …

  10. Open Access 01-12-2024 | Omalizumab | OriginalPaper

    Efficacy of omalizumab in adult patients with allergic bronchopulmonary aspergillosis: a multicentre study in China

    Despite conventional glucocorticoid and antifungal therapy, acute exacerbation and hospitalization occur frequently in patients with allergic bronchopulmonary aspergillosis (ABPA). Whether omalizumab is an effective and safe treatment for adult …

  11. Open Access 01-12-2024 | Cryptococcosis | OriginalPaper

    Pulmonary cryptococcosis complicated with pulmonary aspergillosis: a series of studies and a literature review

    With the development of modern medical and health care, the large-scale use or abuse of broad-spectrum antibiotics, glucocorticoids, and immunosuppressants, the rise of organ transplantation technology, and the increasingly diverse means of tumour …

  12. Open Access 01-12-2024 | Aspergillosis | OriginalPaper

    Covid-19-associated pulmonary aspergillosis in mechanically ventilated patients: incidence and outcome in a French multicenter observational cohort (APICOVID)

    Invasive pulmonary aspergillosis (IPA) is increasingly recognized as a complication of severe COVID-19 in patients who lack host factors traditionally associated with invasive fungal disease [ 1 ]. Virus-induced damage to the airway epithelium …

  13. Open Access 01-12-2024 | COVID-19 | OriginalPaper

    Clinical courses and outcomes of COVID-19 associated pulmonary aspergillosis in 168 patients with the SARS-CoV-2 omicron variant

    Since 2022, the new coronavirus Omicron variant has significantly increased its transmission and immune escape ability compared to previous variants, and has quickly replaced the Delta variant as the dominant strain in the world [ 1 ]. Although the …

  14. 10-08-2023 | Aspergillosis | OriginalPaper

    Aspergillosis Causing Orbital Subperiosteal Abscess in an Immunocompetent Child: A Rare Presentation

    Orbital abscesses are primarily seen in children as complication of ethmoid bacterial sinusitis. We report a case of invasive aspergillosis causing orbital abscess in an immunocompetent child which resolved with surgery followed by antifungal …

  15. Open Access 29-11-2023 | Invasive Aspergillosis | OriginalPaper

    Performance of the Aspergillus galactomannan lateral flow assay with a digital reader for the diagnosis of invasive aspergillosis: a multicenter study

    According to cutting-edge research by Fudan University in Shanghai, China, and the Global Action Fund for Fungal Infections (GAFFI), as many as 300,000 people worldwide are affected by invasive aspergillosis (IA), and currently, an estimated …

  16. Open Access 01-12-2023 | Adenovirus | OriginalPaper

    Severe pediatric adenoviral pneumonia combined with invasive pulmonary aspergillosis

    Adenoviral (ADV) pneumonia is one of the most serious types of community-acquired pneumonia in children [ 1 – 3 ]. It has received attention from physicians at all levels because of its severe clinical presentation, susceptibility to multisystem …

  17. 19-12-2023 | Aspergillosis | Online First

    Atypical Presentation of Invasive Aspergillosis in the Infralabial Region of the Face in an Immunocompetent Young Adult: A Case Report

    Aspergillosis is the second most common fungal infection. Aspergillosis can cause a wide range of clinical presentations from asymptomatic lesions to life-threatening invasive conditions. They originate most commonly from the spores that colonize …

  18. Open Access 01-12-2023 | Aspergillosis | OriginalPaper

    Systemic aspergillosis in a patient with interferon gamma receptor 1 deficiency; a case report

    Interferon-gamma receptor deficiency is a heterogeneous spectrum of disease which involves mutations in IFNGR1 , IFNGR2 genes, and the downstream signaling proteins such as STAT1 [ 1 ]. These mutations are associated with immunodeficiency 27 A and …

  19. Open Access 01-12-2023 | Aspergillosis | OriginalPaper

    Prediction of pulmonary aspergillosis in patients with ventilator-associated pneumonia

    Fungi are the deadliest but paradoxically the most disregarded agent of intensive care unit (ICU) acquired infection [ 1 – 3 ]. Once thought to occur mostly in immunocompromised patients, ICU-acquired pulmonary aspergillosis (IPA) has lately been …

  20. Open Access 01-12-2023 | Aspergillosis | OriginalPaper

    Evolution of neuroimaging findings in angioinvasive cerebral aspergillosis in a pediatric patient with leukemia during long-term observation

    The central nervous system is one of the most common sites of aspergillosis involvement in immunocompromised people, just after sinopulmonary infections. Neuroimaging modalities are crucial for the diagnosis of cerebral aspergillosis (CA). Here …

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