Skip to main content
Top
Published in: International Journal of Legal Medicine 4/2016

01-07-2016 | Original Article

Accuracy of scoring of the epiphyses at the knee joint (SKJ) for assessing legal adult age of 18 years

Authors: Ivan Galić, Frane Mihanović, Alice Giuliodori, Federica Conforti, Mariano Cingolani, Roberto Cameriere

Published in: International Journal of Legal Medicine | Issue 4/2016

Login to get access

Abstract

Important aspects of forensic practice are age estimation and discrimination of individuals of unknown age as adults and minors. The developing knee joint was recognized as a potential site for age examination in late adolescence. We analyzed a sample of anteroposterior x-rays of the knee joints from 446 living individuals from Umbria, Italy (234 males and 212 females), aged between 12 and 26 years. We evaluated the ossification of the distal femoral (DF), proximal tibial (PT), and proximal fibular (PF) epiphyses. We took into account possible persistence of the epiphyseal scars in the ossified epiphyses by the adopted stages of those previously introduced by Cameriere et al. (2012). We also used measurements from all three epiphyses to calculate the total score of maturation for the knee joint (SKJ). Cohen Kappa coefficients of intrarater agreement for staging the DF, PT, and PF epiphyses were 0.839, 0.894, and 0.907, while interrater agreement was 0.919, 0.791, and 0.907, respectively. The resulting receiver operating characteristic (ROC) curves of SKJ show better discriminatory power than those for DF, PT, and PF epiphyses in predicting that the participant, either male or female, was an adult or a minor. The areas under the curves for SKJ were 0.991 and 0.968 vs. 0.944, 0.962, 0.974 and 0.891, 0.910, 0.918 for males and females, respectively. The results of the 2 by 2 contingency tables showed that SKJ score of 4 in males and SKJ score of 5 in females were the most suitable cut-off value in discriminating between adults and minors. Principally, the sensitivity test for males was 0.94, with 95 % confidence interval (95 % CI) 0.90 to 0.97 and specificity was 0.96 (95 % CI 0.91 to 0.98). The proportion of correctly classified individuals was 0.95 (95 % CI 0.91 to 0.97). For females, the sensitivity test was 0.89 (95 % CI 0.84 to 0.92) and specificity was 0.92 (95 % CI 0.87 to 0.96), the proportion of correctly classified individuals was 0.90 (95 % CI 0.85 to 0.94). These results indicate that the SKJ method may give valuable supporting information in forensic procedures for discriminating individuals of legal adult age of 18 years. Further studies should address the usefulness of the SKJ method in different populations.
Literature
1.
go back to reference Adams BJ (2007) Forensic anthropology. Chelsea House, New York Adams BJ (2007) Forensic anthropology. Chelsea House, New York
6.
go back to reference Verley Kvittingen A (2010) Negotiating childhood: age assessment in the UK asylum system, Working paper series No 67. Refugee Studies Centre, Oxford Department of International Development, University of Oxford, Oxford Verley Kvittingen A (2010) Negotiating childhood: age assessment in the UK asylum system, Working paper series No 67. Refugee Studies Centre, Oxford Department of International Development, University of Oxford, Oxford
7.
go back to reference Lewis ME, Flavel A (2006) Age assessment of child skeletal remains in forensic contexts. In: Schmitt A, Cunha E, Pinheiro J (eds) Forensic anthropology and medicine. Humana Press, Totowa, pp 243–257CrossRef Lewis ME, Flavel A (2006) Age assessment of child skeletal remains in forensic contexts. In: Schmitt A, Cunha E, Pinheiro J (eds) Forensic anthropology and medicine. Humana Press, Totowa, pp 243–257CrossRef
9.
go back to reference Olze A, Solheim T, Schulz R, Kupfer M, Schmeling A (2010) Evaluation of the radiographic visibility of the root pulp in the lower third molars for the purpose of forensic age estimation in living individuals. Int J Legal Med 124:183–186. doi:10.1007/s00414-009-0415-y CrossRefPubMed Olze A, Solheim T, Schulz R, Kupfer M, Schmeling A (2010) Evaluation of the radiographic visibility of the root pulp in the lower third molars for the purpose of forensic age estimation in living individuals. Int J Legal Med 124:183–186. doi:10.​1007/​s00414-009-0415-y CrossRefPubMed
12.
go back to reference (1975) Law No. 39 of March 8, 1975, on the recognition of the legal age of majority for citizens having reached 18 years old and amendment of other provisions relating to the capacity to act and the right to vote. Rome, Italy (1975) Law No. 39 of March 8, 1975, on the recognition of the legal age of majority for citizens having reached 18 years old and amendment of other provisions relating to the capacity to act and the right to vote. Rome, Italy
14.
go back to reference Knottnerus JA, Muris JW (2009) Assessment of the accuracy of diagnostic tests: the cross-sectional study. The evidence base of clinical diagnosis. Wiley-Blackwell, New York, pp 42–62 Knottnerus JA, Muris JW (2009) Assessment of the accuracy of diagnostic tests: the cross-sectional study. The evidence base of clinical diagnosis. Wiley-Blackwell, New York, pp 42–62
15.
go back to reference Habbema JDF, Eijkemans R, Krijnen P, Knottnerus JA (2009) Analysis of data on the accuracy of diagnostic tests. The evidence base of clinical diagnosis. Wiley-Blackwell, London, pp 118–145 Habbema JDF, Eijkemans R, Krijnen P, Knottnerus JA (2009) Analysis of data on the accuracy of diagnostic tests. The evidence base of clinical diagnosis. Wiley-Blackwell, London, pp 118–145
20.
go back to reference Cardoso HF (2008) Epiphyseal union at the innominate and lower limb in a modern Portuguese skeletal sample, and age estimation in adolescent and young adult male and female skeletons. Am J Phys Anthropol 135:161–170. doi:10.1002/ajpa.20717 CrossRefPubMed Cardoso HF (2008) Epiphyseal union at the innominate and lower limb in a modern Portuguese skeletal sample, and age estimation in adolescent and young adult male and female skeletons. Am J Phys Anthropol 135:161–170. doi:10.​1002/​ajpa.​20717 CrossRefPubMed
21.
go back to reference De Luca S, De Giorgio S, Butti AC, Biagi R, Cingolani M, Cameriere R (2012) Age estimation in children by measurement of open apices in tooth roots: study of a Mexican sample. Forensic Sci Int 221(155):e1–e7. doi:10.1016/j.forsciint.2012.04.026 De Luca S, De Giorgio S, Butti AC, Biagi R, Cingolani M, Cameriere R (2012) Age estimation in children by measurement of open apices in tooth roots: study of a Mexican sample. Forensic Sci Int 221(155):e1–e7. doi:10.​1016/​j.​forsciint.​2012.​04.​026
22.
go back to reference Cameriere R, De Luca S, De Angelis D et al (2012) Reliability of Schmeling’s stages of ossification of medial clavicular epiphyses and its validity to assess 18 years of age in living subjects. Int J Legal Med 126:923–932. doi:10.1007/s00414-012-0769-4 CrossRefPubMed Cameriere R, De Luca S, De Angelis D et al (2012) Reliability of Schmeling’s stages of ossification of medial clavicular epiphyses and its validity to assess 18 years of age in living subjects. Int J Legal Med 126:923–932. doi:10.​1007/​s00414-012-0769-4 CrossRefPubMed
30.
go back to reference Hillewig E, De Tobel J, Cuche O, Vandemaele P, Piette M, Verstraete K (2011) Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach. Eur Radiol 21:757–767. doi:10.1007/s00330-010-1978-1 CrossRefPubMed Hillewig E, De Tobel J, Cuche O, Vandemaele P, Piette M, Verstraete K (2011) Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach. Eur Radiol 21:757–767. doi:10.​1007/​s00330-010-1978-1 CrossRefPubMed
31.
go back to reference Hillewig E, Degroote J, Van der Paelt T et al (2013) Magnetic resonance imaging of the sternal extremity of the clavicle in forensic age estimation: towards more sound age estimates. Int J Legal Med 127:677–689. doi:10.1007/s00414-012-0798-z CrossRefPubMed Hillewig E, Degroote J, Van der Paelt T et al (2013) Magnetic resonance imaging of the sternal extremity of the clavicle in forensic age estimation: towards more sound age estimates. Int J Legal Med 127:677–689. doi:10.​1007/​s00414-012-0798-z CrossRefPubMed
35.
go back to reference Saint-Martin P, Rerolle C, Dedouit F, Rousseau H, Rouge D, Telmon N (2014) Evaluation of an automatic method for forensic age estimation by magnetic resonance imaging of the distal tibial epiphysis—a preliminary study focusing on the 18-year threshold. Int J Legal Med 128:675–683. doi:10.1007/s00414-014-0987-z CrossRefPubMed Saint-Martin P, Rerolle C, Dedouit F, Rousseau H, Rouge D, Telmon N (2014) Evaluation of an automatic method for forensic age estimation by magnetic resonance imaging of the distal tibial epiphysis—a preliminary study focusing on the 18-year threshold. Int J Legal Med 128:675–683. doi:10.​1007/​s00414-014-0987-z CrossRefPubMed
36.
go back to reference Saint-Martin P, Rerolle C, Pucheux J, Dedouit F, Telmon N (2014) Contribution of distal femur MRI to the determination of the 18-year limit in forensic age estimation. Int J Legal Med. doi:10.1007/s00414-014-1020-2 Saint-Martin P, Rerolle C, Pucheux J, Dedouit F, Telmon N (2014) Contribution of distal femur MRI to the determination of the 18-year limit in forensic age estimation. Int J Legal Med. doi:10.​1007/​s00414-014-1020-2
37.
go back to reference Krämer JA, Schmidt S, Jurgens KU, Lentschig M, Schmeling A, Vieth V (2014) The use of magnetic resonance imaging to examine ossification of the proximal tibial epiphysis for forensic age estimation in living individuals. Forensic Sci Med Pathol 10:306–313. doi:10.1007/s12024-014-9559-2 CrossRefPubMed Krämer JA, Schmidt S, Jurgens KU, Lentschig M, Schmeling A, Vieth V (2014) The use of magnetic resonance imaging to examine ossification of the proximal tibial epiphysis for forensic age estimation in living individuals. Forensic Sci Med Pathol 10:306–313. doi:10.​1007/​s12024-014-9559-2 CrossRefPubMed
40.
go back to reference Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276. doi:10.1007/s00414-011-0554-9 CrossRefPubMed Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276. doi:10.​1007/​s00414-011-0554-9 CrossRefPubMed
42.
go back to reference Pyle SI, Hoerr NL (1955) Radiographic atlas of skeletal development of the knee. Charles C Thomas, Springfield Pyle SI, Hoerr NL (1955) Radiographic atlas of skeletal development of the knee. Charles C Thomas, Springfield
44.
go back to reference O’Connor JE, Coyle J, Bogue C, Spence LD, Last J (2014) Age prediction formulae from radiographic assessment of skeletal maturation at the knee in an Irish population. Forensic Sci Int 234(188):e1–e8. doi:10.1016/j.forsciint.2013.10.032 O’Connor JE, Coyle J, Bogue C, Spence LD, Last J (2014) Age prediction formulae from radiographic assessment of skeletal maturation at the knee in an Irish population. Forensic Sci Int 234(188):e1–e8. doi:10.​1016/​j.​forsciint.​2013.​10.​032
45.
go back to reference O’Connor JE, Coyle J, Spence LD, Last J (2013) Epiphyseal maturity indicators at the knee and their relationship to chronological age: results of an Irish population study. Clin Anat 26:755–767. doi:10.1002/ca.22122 CrossRefPubMed O’Connor JE, Coyle J, Spence LD, Last J (2013) Epiphyseal maturity indicators at the knee and their relationship to chronological age: results of an Irish population study. Clin Anat 26:755–767. doi:10.​1002/​ca.​22122 CrossRefPubMed
47.
go back to reference Schaefer MC, Black SM (2005) Comparison of ages of epiphyseal union in North American and Bosnian skeletal material. J Forensic Sci 50:777–784CrossRefPubMed Schaefer MC, Black SM (2005) Comparison of ages of epiphyseal union in North American and Bosnian skeletal material. J Forensic Sci 50:777–784CrossRefPubMed
48.
go back to reference Roche AF, Chumlea W, Thissen D (1988) Assessing the skeletal maturity of the hand-wrist: Fels method. Thomas, Springfield Roche AF, Chumlea W, Thissen D (1988) Assessing the skeletal maturity of the hand-wrist: Fels method. Thomas, Springfield
49.
go back to reference Roche AF, Wainer H, Thissen D (1975) Skeletal maturity: the knee joint as a biological indicator. Plenum Medical Book Co, New York Roche AF, Wainer H, Thissen D (1975) Skeletal maturity: the knee joint as a biological indicator. Plenum Medical Book Co, New York
50.
go back to reference McKern TW, Stewart TD (1957) In: United States Army Quartermaster Research Development C (ed) Skeletal age changes in young American males analysed from the standpoint of age identification. Headquarters, Quartermaster Research & Development Command, Natick, p 170CrossRef McKern TW, Stewart TD (1957) In: United States Army Quartermaster Research Development C (ed) Skeletal age changes in young American males analysed from the standpoint of age identification. Headquarters, Quartermaster Research & Development Command, Natick, p 170CrossRef
51.
go back to reference Cameriere R, Cingolani M, Giuliodori A, De Luca S, Ferrante L (2012) Radiographic analysis of epiphyseal fusion at knee joint to assess likelihood of having attained 18 years of age. Int J Legal Med 126:889–899. doi:10.1007/s00414-012-0754-y CrossRefPubMed Cameriere R, Cingolani M, Giuliodori A, De Luca S, Ferrante L (2012) Radiographic analysis of epiphyseal fusion at knee joint to assess likelihood of having attained 18 years of age. Int J Legal Med 126:889–899. doi:10.​1007/​s00414-012-0754-y CrossRefPubMed
52.
go back to reference Weiss E, Desilva J, Zipfel B (2012) Brief communication: radiographic study of metatarsal one basal epiphyseal fusion: a note of caution on age determination. Am J Phys Anthropol 147:489–492. doi:10.1002/ajpa.22022 CrossRefPubMed Weiss E, Desilva J, Zipfel B (2012) Brief communication: radiographic study of metatarsal one basal epiphyseal fusion: a note of caution on age determination. Am J Phys Anthropol 147:489–492. doi:10.​1002/​ajpa.​22022 CrossRefPubMed
54.
57.
go back to reference Fletcher R, Fletcher S (2005) Diagnosis. In: Fletcher R, Fletcher S (eds) Clinical epidemiology the essentials. Wolters, Kluwer, Lippincott, Williams & Wilkins, Baltimore, pp 35–58 Fletcher R, Fletcher S (2005) Diagnosis. In: Fletcher R, Fletcher S (eds) Clinical epidemiology the essentials. Wolters, Kluwer, Lippincott, Williams & Wilkins, Baltimore, pp 35–58
59.
go back to reference The Italian National Institute of Statistics (2014) Resident population on the January, 1st 2014. IStat The Italian National Institute of Statistics (2014) Resident population on the January, 1st 2014. IStat
61.
go back to reference Rai B, Kaur J (2013) Dental age estimation. Evidence-based forensic dentistry. Springer, Berlin Heidelberg, pp 35–63CrossRef Rai B, Kaur J (2013) Dental age estimation. Evidence-based forensic dentistry. Springer, Berlin Heidelberg, pp 35–63CrossRef
62.
go back to reference Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G (2000) Effects of ethnicity on skeletal maturation: consequences for forensic age estimations. Int J Legal Med 113:253–258CrossRefPubMed Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G (2000) Effects of ethnicity on skeletal maturation: consequences for forensic age estimations. Int J Legal Med 113:253–258CrossRefPubMed
65.
go back to reference Schmeling A, Garamendi PM, Prieto JL, Landa MI (2011) Forensic age estimation in unaccompanied minors and young living adults. In: Vieira DN (ed) Forensic medicine - from old problems to new challenges. InTech Europe Rijeka, Croatia, pp 77–120 Schmeling A, Garamendi PM, Prieto JL, Landa MI (2011) Forensic age estimation in unaccompanied minors and young living adults. In: Vieira DN (ed) Forensic medicine - from old problems to new challenges. InTech Europe Rijeka, Croatia, pp 77–120
67.
go back to reference Thevissen P, Altalie S, Brkić H et al (2013) Comparing 14 country-specific populations on third molars development: consequences for age predictions of individuals with different geographic and biological origin. J Forensic Odontostomatol 31:87–88 Thevissen P, Altalie S, Brkić H et al (2013) Comparing 14 country-specific populations on third molars development: consequences for age predictions of individuals with different geographic and biological origin. J Forensic Odontostomatol 31:87–88
68.
go back to reference Cameriere R, Ferrante L, De Angelis D, Scarpino F, Galli F (2008) The comparison between measurement of open apices of third molars and Demirjian stages to test chronological age of over 18 year olds in living subjects. Int J Legal Med 122:493–497. doi:10.1007/s00414-008-0279-6 CrossRefPubMed Cameriere R, Ferrante L, De Angelis D, Scarpino F, Galli F (2008) The comparison between measurement of open apices of third molars and Demirjian stages to test chronological age of over 18 year olds in living subjects. Int J Legal Med 122:493–497. doi:10.​1007/​s00414-008-0279-6 CrossRefPubMed
74.
go back to reference Ambarkova V, Galic I, Vodanovic M, Biocina-Lukenda D, Brkic H (2014) Dental age estimation using Demirjian and Willems methods: cross sectional study on children from the former Yugoslav Republic of Macedonia. Forensic Sci Int 234(187):e1–e7. doi:10.1016/j.forsciint.2013.10.024 Ambarkova V, Galic I, Vodanovic M, Biocina-Lukenda D, Brkic H (2014) Dental age estimation using Demirjian and Willems methods: cross sectional study on children from the former Yugoslav Republic of Macedonia. Forensic Sci Int 234(187):e1–e7. doi:10.​1016/​j.​forsciint.​2013.​10.​024
76.
77.
go back to reference Tise M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A (2011) Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med 125:411–416. doi:10.1007/s00414-010-0541-6 CrossRefPubMed Tise M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A (2011) Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med 125:411–416. doi:10.​1007/​s00414-010-0541-6 CrossRefPubMed
78.
go back to reference Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist, 2nd edn. Stanford University Press, Stanford, p xvi, 256 Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist, 2nd edn. Stanford University Press, Stanford, p xvi, 256
79.
go back to reference Baccetti T, Franchi L, McNamara JA (2005) The cervical vertebral maturation (CVM) method for the assessment of optimal treatment timing in dentofacial orthopedics. Semin Orthod 11:119–129CrossRef Baccetti T, Franchi L, McNamara JA (2005) The cervical vertebral maturation (CVM) method for the assessment of optimal treatment timing in dentofacial orthopedics. Semin Orthod 11:119–129CrossRef
83.
go back to reference Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A (2010) Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med 124:149–154. doi:10.1007/s00414-009-0398-8 CrossRefPubMed Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A (2010) Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med 124:149–154. doi:10.​1007/​s00414-009-0398-8 CrossRefPubMed
84.
go back to reference Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A (2010) Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med 124:321–325. doi:10.1007/s00414-010-0448-2 CrossRefPubMed Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A (2010) Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med 124:321–325. doi:10.​1007/​s00414-010-0448-2 CrossRefPubMed
85.
go back to reference Wittschieber D, Schulz R, Vieth V et al (2014) The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study. Forensic Sci Med Pathol 10:163–169. doi:10.1007/s12024-013-9511-x CrossRefPubMed Wittschieber D, Schulz R, Vieth V et al (2014) The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study. Forensic Sci Med Pathol 10:163–169. doi:10.​1007/​s12024-013-9511-x CrossRefPubMed
87.
go back to reference The Organisation for Economic Co-operation and Development (2014) International migration outlook 2014. OECD Publishing, Paris, p 266 The Organisation for Economic Co-operation and Development (2014) International migration outlook 2014. OECD Publishing, Paris, p 266
89.
go back to reference The Organisation for Economic Co-operation and Development (2013) International migration outlook 2013. OECD Publishing, Paris, p 264 The Organisation for Economic Co-operation and Development (2013) International migration outlook 2013. OECD Publishing, Paris, p 264
90.
go back to reference The Organisation for Economic Co-operation and Development (2012) International migration outlook 2012. OECD Publishing, Paris, p 242 The Organisation for Economic Co-operation and Development (2012) International migration outlook 2012. OECD Publishing, Paris, p 242
91.
go back to reference Thevissen PW, Kvaal SI, Willems G (2012) Ethics in age estimation of unaccompanied minors. J Forensic Odontostomatol 30(Suppl 1):84–102PubMed Thevissen PW, Kvaal SI, Willems G (2012) Ethics in age estimation of unaccompanied minors. J Forensic Odontostomatol 30(Suppl 1):84–102PubMed
92.
94.
go back to reference Aynsley-Green A, Cole TJ, Crawley H, Lessof N, Boag LR, Wallace RM (2012) Medical, statistical, ethical and human rights considerations in the assessment of age in children and young people subject to immigration control. Br Med Bull 102:17–42. doi:10.1093/bmb/lds014 CrossRefPubMed Aynsley-Green A, Cole TJ, Crawley H, Lessof N, Boag LR, Wallace RM (2012) Medical, statistical, ethical and human rights considerations in the assessment of age in children and young people subject to immigration control. Br Med Bull 102:17–42. doi:10.​1093/​bmb/​lds014 CrossRefPubMed
95.
go back to reference Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8. doi:10.1007/s00414-003-0404-5 CrossRefPubMed Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8. doi:10.​1007/​s00414-003-0404-5 CrossRefPubMed
Metadata
Title
Accuracy of scoring of the epiphyses at the knee joint (SKJ) for assessing legal adult age of 18 years
Authors
Ivan Galić
Frane Mihanović
Alice Giuliodori
Federica Conforti
Mariano Cingolani
Roberto Cameriere
Publication date
01-07-2016
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Legal Medicine / Issue 4/2016
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-016-1348-x

Other articles of this Issue 4/2016

International Journal of Legal Medicine 4/2016 Go to the issue