Skip to main content
Top
Published in: International Journal of Legal Medicine 4/2013

01-07-2013 | Original Article

Age dependence of epiphyseal ossification of the distal radius in ultrasound diagnostics

Authors: S. Schmidt, M. Schiborr, H. Pfeiffer, A. Schmeling, R. Schulz

Published in: International Journal of Legal Medicine | Issue 4/2013

Login to get access

Abstract

By determining the ossification stage of the distal radial epiphysis, it is possible to gain important information to help clarify the question of whether various legally relevant age limits have been exceeded. Any examination of the hand by means of projection radiography such as that used in conventional skeletal age diagnostics is strictly regulated for reasons of radiation hygiene. In many areas of the law, there are no basic legal provisions authorising the performance of X-ray examinations. The present study examines the applicability of ultrasound diagnostics in assessing ossification processes in the distal radius. To this end, the ossification stages of the distal radial epiphysis were determined in 306 female and 309 male study participants aged between 10 and 25 years. In the female gender, ossification stage III was determined at an age of 13.4 years at the earliest, and ossification stage IV at 15.0 years at the earliest. In the male gender, ossification stage III was not observed until 14.3 years, and ossification stage IV not until 15.2 years. In the practice of forensic age estimation in living persons, sonographic examination of the distal radius in areas of application with no legal basis for authorising X-ray examinations makes it possible to improve the accuracy of age diagnosis by including criteria of skeletal maturation. In view of the existing legislative basis for the use of X-rays on human subjects, the exposure of individuals to radiation can be minimised.
Literature
1.
go back to reference Baumann U, Schulz R, Heinecke A, Schmeling A, Schmidt S (2009) Reference study on the time frame for ossification of the distal radius and ulnar epiphysis on the hand radiograph. Forensic Sci Int 191:15–18PubMedCrossRef Baumann U, Schulz R, Heinecke A, Schmeling A, Schmidt S (2009) Reference study on the time frame for ossification of the distal radius and ulnar epiphysis on the hand radiograph. Forensic Sci Int 191:15–18PubMedCrossRef
2.
go back to reference Bernhard W (1988) Reifungsdiagnose an Lebenden. In: Knußmann R (ed) Wesen und Methoden der Anthropologie, 1. Teil, Wissenschaftstheorie, Geschichte, morphologische Methoden. Thieme, Stuttgart Bernhard W (1988) Reifungsdiagnose an Lebenden. In: Knußmann R (ed) Wesen und Methoden der Anthropologie, 1. Teil, Wissenschaftstheorie, Geschichte, morphologische Methoden. Thieme, Stuttgart
3.
go back to reference Braselmann A (1974) Die Bestimmung des Knochenalters am kindlichen Ellenbogengelenk – Studie an 408 Kindern im Vergleich mit der Handwurzelossifikation. Dissertation, Heidelberg Braselmann A (1974) Die Bestimmung des Knochenalters am kindlichen Ellenbogengelenk – Studie an 408 Kindern im Vergleich mit der Handwurzelossifikation. Dissertation, Heidelberg
4.
go back to reference Cameriere R, de Luca S, de Angelis D, Merelli V, Giuliodori A, Cingolani M, Cattaneo C, Ferrante L (2012) Reliability of Schmeling’s stages of ossification of medial clavicular epiphyses and its validity to assess 18 years of age in living subjects. Int J Legal Med 126:923–932PubMedCrossRef Cameriere R, de Luca S, de Angelis D, Merelli V, Giuliodori A, Cingolani M, Cattaneo C, Ferrante L (2012) Reliability of Schmeling’s stages of ossification of medial clavicular epiphyses and its validity to assess 18 years of age in living subjects. Int J Legal Med 126:923–932PubMedCrossRef
5.
go back to reference Cameriere R, de Luca S, Biagi R, Cingolani M, Farronato G, Ferrante L (2012) Accuracy of three age estimation methods in children by measurements of developing teeth and carpals and epiphyses of the ulna and radius. J Forensic Sci 57:1263–1270PubMedCrossRef Cameriere R, de Luca S, Biagi R, Cingolani M, Farronato G, Ferrante L (2012) Accuracy of three age estimation methods in children by measurements of developing teeth and carpals and epiphyses of the ulna and radius. J Forensic Sci 57:1263–1270PubMedCrossRef
6.
go back to reference Dünkel F, Grzywa J, Horsfield P, Pruin I (2010) Juvenile justice systems in Europe. Forum, Godesberg Dünkel F, Grzywa J, Horsfield P, Pruin I (2010) Juvenile justice systems in Europe. Forum, Godesberg
7.
go back to reference Dvorak J, George J, Junge A, Hodler J (2007) Age determination by magnetic resonance imaging of the wrist in adolescent male football players. Br J Sports Med 41:45–52PubMedCrossRef Dvorak J, George J, Junge A, Hodler J (2007) Age determination by magnetic resonance imaging of the wrist in adolescent male football players. Br J Sports Med 41:45–52PubMedCrossRef
8.
go back to reference Dvorak J, George J, Junge A, Hodler J (2007) Application of MRI of the wrist for age determination in international U-17 soccer competitions. Br J Sports Med 41:497–500PubMedCrossRef Dvorak J, George J, Junge A, Hodler J (2007) Application of MRI of the wrist for age determination in international U-17 soccer competitions. Br J Sports Med 41:497–500PubMedCrossRef
9.
go back to reference Dvorak J (2009) Detecting over-age players using wrist MRI: science partnering with sport to ensure fair play. Br J Sports Med 43:884–885PubMedCrossRef Dvorak J (2009) Detecting over-age players using wrist MRI: science partnering with sport to ensure fair play. Br J Sports Med 43:884–885PubMedCrossRef
10.
go back to reference Gefferth K (1970) Ein Verfahren zur Bestimmung des biologischen Knochenalters. Acta Paediatr Acad Sci Hung 11:59–66PubMed Gefferth K (1970) Ein Verfahren zur Bestimmung des biologischen Knochenalters. Acta Paediatr Acad Sci Hung 11:59–66PubMed
11.
go back to reference Grashey R, Birkner R (1964) Atlas typischer Röntgenbilder vom normalen Menschen. Urban & Schwarzenberg, München Grashey R, Birkner R (1964) Atlas typischer Röntgenbilder vom normalen Menschen. Urban & Schwarzenberg, München
12.
go back to reference Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist. Stanford University Press, Stanford Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist. Stanford University Press, Stanford
13.
go back to reference Hansman CF, Maresh MM (1961) A longitudinal study of skeletal maturation. Am J Dis Child 101:305–321PubMed Hansman CF, Maresh MM (1961) A longitudinal study of skeletal maturation. Am J Dis Child 101:305–321PubMed
14.
go back to reference Khan KM, Miller BS, Hoggard E, Somani A, Sarafoglou K (2009) Application of ultrasound for bone age estimation in clinical practice. J Pediatr 154:243–247PubMedCrossRef Khan KM, Miller BS, Hoggard E, Somani A, Sarafoglou K (2009) Application of ultrasound for bone age estimation in clinical practice. J Pediatr 154:243–247PubMedCrossRef
15.
go back to reference Knussmann R (1996) Vergleichende Biologie des Menschen, Lehrbuch der Anthropologie und Humangenetik. Fischer, Stuttgart Knussmann R (1996) Vergleichende Biologie des Menschen, Lehrbuch der Anthropologie und Humangenetik. Fischer, Stuttgart
16.
go back to reference Lockemann U, Fuhrmann A, Püschel K, Schmeling A, Geserick G (2004) Arbeitsgemeinschaft für Forensische Altersdiagnostik der Deutschen Gesellschaft für Rechtsmedizin: Empfehlungen für die Altersdiagnostik bei Jugendlichen und jungen Erwachsenen außerhalb des Strafverfahrens. Rechtsmedizin 14:123–125CrossRef Lockemann U, Fuhrmann A, Püschel K, Schmeling A, Geserick G (2004) Arbeitsgemeinschaft für Forensische Altersdiagnostik der Deutschen Gesellschaft für Rechtsmedizin: Empfehlungen für die Altersdiagnostik bei Jugendlichen und jungen Erwachsenen außerhalb des Strafverfahrens. Rechtsmedizin 14:123–125CrossRef
17.
go back to reference Olze A, Hertel J, Schulz R, Schmeling A (2012) Altersabhängigkeit der Sekundärdentinanlagerung im Pulpencavum. Orthopantomogrammstudie. Rechtsmedizin 22:374–378CrossRef Olze A, Hertel J, Schulz R, Schmeling A (2012) Altersabhängigkeit der Sekundärdentinanlagerung im Pulpencavum. Orthopantomogrammstudie. Rechtsmedizin 22:374–378CrossRef
18.
go back to reference Olze A, Hertel J, Schulz R, Wierer T, Schmeling A (2012) Radiographic evaluation of Gustafson’s criteria for the purpose of forensic age diagnostics. Int J Legal Med 126:615–621PubMedCrossRef Olze A, Hertel J, Schulz R, Wierer T, Schmeling A (2012) Radiographic evaluation of Gustafson’s criteria for the purpose of forensic age diagnostics. Int J Legal Med 126:615–621PubMedCrossRef
19.
go back to reference Olze A, van Niekerk P, Schulz R, Ribbecke S, Schmeling A (2012) The influence of impaction on the rate of third molar mineralisation in male Black Africans. Int J Legal Med 126:869–874PubMedCrossRef Olze A, van Niekerk P, Schulz R, Ribbecke S, Schmeling A (2012) The influence of impaction on the rate of third molar mineralisation in male Black Africans. Int J Legal Med 126:869–874PubMedCrossRef
20.
go back to reference Pelech L, Pechstein J (1976) Vergleichende Untersuchungen über die Entwicklung des Skelettalters bei tschechischen und süddeutschen Kindern. Arztl Jugendkd 67:23–28PubMed Pelech L, Pechstein J (1976) Vergleichende Untersuchungen über die Entwicklung des Skelettalters bei tschechischen und süddeutschen Kindern. Arztl Jugendkd 67:23–28PubMed
21.
go back to reference Pelsmaekers B, Loos R, Carels C, Derom C, Vlietinck R (1997) The genetic contribution to dental maturation. J Dent Res 76:1337–1340PubMedCrossRef Pelsmaekers B, Loos R, Carels C, Derom C, Vlietinck R (1997) The genetic contribution to dental maturation. J Dent Res 76:1337–1340PubMedCrossRef
22.
go back to reference Quirmbach F, Ramsthaler F, Verhoff MA (2009) Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years. Int J Legal Med 123:241–245PubMedCrossRef Quirmbach F, Ramsthaler F, Verhoff MA (2009) Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years. Int J Legal Med 123:241–245PubMedCrossRef
23.
go back to reference Roche AF, Chumlea WC, Thissen D (1988) Assessing the skeletal maturity of the hand-wrist: Fels method. Thomas, Springfield Roche AF, Chumlea WC, Thissen D (1988) Assessing the skeletal maturity of the hand-wrist: Fels method. Thomas, Springfield
24.
go back to reference Roche AF, French NY (1970) Differences in skeletal maturity levels between the knee and hand. Am J Roentgenol Radium Ther Nucl Med 109:307–312PubMedCrossRef Roche AF, French NY (1970) Differences in skeletal maturity levels between the knee and hand. Am J Roentgenol Radium Ther Nucl Med 109:307–312PubMedCrossRef
25.
go back to reference Rösing FW (2000) Forensische Altersdiagnose: Statistik, Arbeitsregeln und Darstellung. In: Oehmichen M, Geserick G (eds) Osteologische Identifikation (Research in Legal Medicine/Rechtsmedizinische Forschungsergebnisse). Schmidt-Römhild, Lübeck Rösing FW (2000) Forensische Altersdiagnose: Statistik, Arbeitsregeln und Darstellung. In: Oehmichen M, Geserick G (eds) Osteologische Identifikation (Research in Legal Medicine/Rechtsmedizinische Forschungsergebnisse). Schmidt-Römhild, Lübeck
26.
go back to reference Santoro V, Roca R, Donno A de, Fiandaca C, Pinto G, Tafuri S, Introna F (2012) Applicability of Greulich and Pyle and Demirijan aging methods to sample of Italian population. Forensic Sci Int 221(1–3):153.e1–153.e5 Santoro V, Roca R, Donno A de, Fiandaca C, Pinto G, Tafuri S, Introna F (2012) Applicability of Greulich and Pyle and Demirijan aging methods to sample of Italian population. Forensic Sci Int 221(1–3):153.e1–153.e5
27.
go back to reference Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rösing FW, Rötzscher K, Geserick G (2008) Criteria for age estimation in living individuals. Int J Legal Med 122:457–460PubMedCrossRef Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rösing FW, Rötzscher K, Geserick G (2008) Criteria for age estimation in living individuals. Int J Legal Med 122:457–460PubMedCrossRef
28.
go back to reference Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G (2000) Effects of ethnicity on skeletal maturation—consequences for forensic age estimations. Int J Legal Med 113:253–258PubMedCrossRef Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G (2000) Effects of ethnicity on skeletal maturation—consequences for forensic age estimations. Int J Legal Med 113:253–258PubMedCrossRef
29.
go back to reference Schmeling A, Schulz R, Reisinger W, Mühler M, Wernecke K-D, Geserick G (2004) Studies on the time frame for ossification of medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8PubMedCrossRef Schmeling A, Schulz R, Reisinger W, Mühler M, Wernecke K-D, Geserick G (2004) Studies on the time frame for ossification of medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8PubMedCrossRef
30.
go back to reference Schmid F, Moll H (1960) Atlas der normalen und pathologischen Handskelettentwicklung. Springer, BerlinCrossRef Schmid F, Moll H (1960) Atlas der normalen und pathologischen Handskelettentwicklung. Springer, BerlinCrossRef
31.
go back to reference Schmidt S, Baumann U, Schulz R, Reisinger W, Schmeling A (2008) A Study of age dependence of epiphyseal ossification of the hand skeleton. Int J Legal Med 122:51–54PubMedCrossRef Schmidt S, Baumann U, Schulz R, Reisinger W, Schmeling A (2008) A Study of age dependence of epiphyseal ossification of the hand skeleton. Int J Legal Med 122:51–54PubMedCrossRef
32.
go back to reference Schmidt S, Koch B, Mühler M, Reisinger W, Schmeling A (2007) Optimizing the Thiemann-Nitz method for skeletal age determination for forensic age diagnostics in live subjects. Scand J Forensic Sci 13:5–7 Schmidt S, Koch B, Mühler M, Reisinger W, Schmeling A (2007) Optimizing the Thiemann-Nitz method for skeletal age determination for forensic age diagnostics in live subjects. Scand J Forensic Sci 13:5–7
33.
go back to reference Schmidt S, Koch B, Schulz R, Reisinger W, Schmeling A (2007) Comparative analysis of the applicability of the skeletal age determination methods of Greulich-Pyle and Thiemann-Nitz for forensic age estimation in living subjects. Int J Legal Med 121:293–296PubMedCrossRef Schmidt S, Koch B, Schulz R, Reisinger W, Schmeling A (2007) Comparative analysis of the applicability of the skeletal age determination methods of Greulich-Pyle and Thiemann-Nitz for forensic age estimation in living subjects. Int J Legal Med 121:293–296PubMedCrossRef
34.
go back to reference Schmidt S, Koch B, Schulz R, Reisinger W, Schmeling A (2008) Studies in use of the Greulich-Pyle skeletal age method to assess criminal liability. Leg med (Tokyo) 10:190–195CrossRef Schmidt S, Koch B, Schulz R, Reisinger W, Schmeling A (2008) Studies in use of the Greulich-Pyle skeletal age method to assess criminal liability. Leg med (Tokyo) 10:190–195CrossRef
35.
go back to reference Schmidt S, Mühler M, Schmeling A, Reisinger W, Schulz R (2007) Magnetic resonance imaging of the clavicular ossification. Int J Legal Med 121:321–324PubMedCrossRef Schmidt S, Mühler M, Schmeling A, Reisinger W, Schulz R (2007) Magnetic resonance imaging of the clavicular ossification. Int J Legal Med 121:321–324PubMedCrossRef
36.
go back to reference Schmidt S, Nitz I, Schulz R, Schmeling A (2008) Applicability of the skeletal age determination method of Tanner and Whitehouse for forensic age diagnostics. Int J Legal Med 122:309–314PubMedCrossRef Schmidt S, Nitz I, Schulz R, Schmeling A (2008) Applicability of the skeletal age determination method of Tanner and Whitehouse for forensic age diagnostics. Int J Legal Med 122:309–314PubMedCrossRef
37.
go back to reference Schmidt S, Nitz I, Schulz R, Tsokos M, Schmeling A (2009) The digital atlas of skeletal maturity by Gilsanz and Ratib: a suitable alternative for age estimation of living individuals in criminal proceedings? Int J Legal Med 123:489–494PubMedCrossRef Schmidt S, Nitz I, Schulz R, Tsokos M, Schmeling A (2009) The digital atlas of skeletal maturity by Gilsanz and Ratib: a suitable alternative for age estimation of living individuals in criminal proceedings? Int J Legal Med 123:489–494PubMedCrossRef
38.
go back to reference Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276PubMedCrossRef Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276PubMedCrossRef
39.
go back to reference Schmidt S, Schmeling A, Zwiesigk P, Schiborr M, Pfeiffer H, Schulz R (2011) Ultrasound studies on age dependency of epiphyseal ossification of the distal radius. Scand J Forensic Sci 17:17–20 Schmidt S, Schmeling A, Zwiesigk P, Schiborr M, Pfeiffer H, Schulz R (2011) Ultrasound studies on age dependency of epiphyseal ossification of the distal radius. Scand J Forensic Sci 17:17–20
40.
go back to reference Schulz R, Zwiesigk P, Schiborr M, Schmidt S, Schmeling A (2008) Ultrasound studies on the time course of clavicular ossification. Int J Legal Med 122:163–167PubMedCrossRef Schulz R, Zwiesigk P, Schiborr M, Schmidt S, Schmeling A (2008) Ultrasound studies on the time course of clavicular ossification. Int J Legal Med 122:163–167PubMedCrossRef
41.
go back to reference de Sousa F, Schuster W (1975) Bestimmung des Knochenalters. Kinderarzt 6:421–428 de Sousa F, Schuster W (1975) Bestimmung des Knochenalters. Kinderarzt 6:421–428
42.
go back to reference Tanner JM, Whitehouse RH, Healy MJR (1962) A new system for estimating skeletal maturity from the hand and wrist with standard derived from a study of 2600 healthy British children. Part II. The scoring system. Int Child Centre, Paris Tanner JM, Whitehouse RH, Healy MJR (1962) A new system for estimating skeletal maturity from the hand and wrist with standard derived from a study of 2600 healthy British children. Part II. The scoring system. Int Child Centre, Paris
43.
go back to reference Thiemann H-H, Nitz I, Schmeling A (2006) Röntgenatlas der normalen Hand im Kindesalter. Thieme, Stuttgart Thiemann H-H, Nitz I, Schmeling A (2006) Röntgenatlas der normalen Hand im Kindesalter. Thieme, Stuttgart
44.
go back to reference Tisè M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A (2011) Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med 125:411–416PubMedCrossRef Tisè M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A (2011) Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med 125:411–416PubMedCrossRef
Metadata
Title
Age dependence of epiphyseal ossification of the distal radius in ultrasound diagnostics
Authors
S. Schmidt
M. Schiborr
H. Pfeiffer
A. Schmeling
R. Schulz
Publication date
01-07-2013
Publisher
Springer-Verlag
Published in
International Journal of Legal Medicine / Issue 4/2013
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-013-0871-2

Other articles of this Issue 4/2013

International Journal of Legal Medicine 4/2013 Go to the issue