Skip to main content
Top
Published in: International Journal of Legal Medicine 4/2016

01-07-2016 | Original Article

Age estimation based on pelvic ossification using regression models from conventional radiography

Authors: Kui Zhang, Xiao-ai Dong, Fei Fan, Zhen-hua Deng

Published in: International Journal of Legal Medicine | Issue 4/2016

Login to get access

Abstract

To establish regression models for age estimation from the combination of the ossification of iliac crest and ischial tuberosity. One thousand three hundred and seventy-nine conventional pelvic radiographs at the West China Hospital of Sichuan University between January 2010 and June 2012 were evaluated retrospectively. The receiver operating characteristic analysis was performed to measure the value of estimation of 18 years of age with the classification scheme for the iliac crest and ischial tuberosity. Regression analysis was performed, and formulas for calculating approximate chronological age according to the combination developmental status of the ossification for the iliac crest and ischial tuberosity were developed. The areas under the receiver operating characteristic (ROC) curves were above 0.9 (p < 0.001), indicating a good prediction of the grading systems, and the cubic regression model was found to have the highest R-square value (R 2 = 0.744 for female and R 2 = 0.753 for male). The present classification scheme for apophyseal iliac crest ossification and the ischial tuberosity may be used for age estimation. And the present established cubic regression model according to the combination developmental status of the ossification for the iliac crest and ischial tuberosity can be used for age estimation.
Literature
1.
go back to reference Gaskin CM, Kalm S (2011) Skeletal development of the hand and wrist: a radiographic atlas and digital bone age companion. Oxford University Press, USA, pp 30–42CrossRef Gaskin CM, Kalm S (2011) Skeletal development of the hand and wrist: a radiographic atlas and digital bone age companion. Oxford University Press, USA, pp 30–42CrossRef
2.
go back to reference De Sanctis V, Di Maio S, Soliman AT, Raiola G, Elalaily R, Millimaggi G (2014) Hand X-ray in pediatric endocrinology: skeletal age assessment and beyond. Indian J Endocrinol Metab 18:S63–S71CrossRef De Sanctis V, Di Maio S, Soliman AT, Raiola G, Elalaily R, Millimaggi G (2014) Hand X-ray in pediatric endocrinology: skeletal age assessment and beyond. Indian J Endocrinol Metab 18:S63–S71CrossRef
3.
go back to reference Fishman LS (1982) Radiographic evaluation of skeletal maturation. A clinically oriented method based on hand-wrist films. Angle Orthod 52:88–112PubMed Fishman LS (1982) Radiographic evaluation of skeletal maturation. A clinically oriented method based on hand-wrist films. Angle Orthod 52:88–112PubMed
4.
go back to reference Darmawan MF, Yusuf SM, Abdul Kadir MR, Haron H (2015) Age estimation based on bone length using 12 regression models of left hand X-ray images for Asian children below 19 years old. Leg Med (Tokyo) 17:71–78CrossRef Darmawan MF, Yusuf SM, Abdul Kadir MR, Haron H (2015) Age estimation based on bone length using 12 regression models of left hand X-ray images for Asian children below 19 years old. Leg Med (Tokyo) 17:71–78CrossRef
5.
go back to reference Schmidt S, Nitz I, Ribbecke S, Schulz R, Pfeiffer H, Schmeling A (2013) Skeletal age determination of the hand: a comparison of methods. Int J Legal Med 127:691–698CrossRef Schmidt S, Nitz I, Ribbecke S, Schulz R, Pfeiffer H, Schmeling A (2013) Skeletal age determination of the hand: a comparison of methods. Int J Legal Med 127:691–698CrossRef
6.
go back to reference Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8CrossRef Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med 118:5–8CrossRef
7.
go back to reference Wittschieber D, Schulz R, Vieth V et al (2014) The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study. Forensic Sci Med Pathol 10:163–169CrossRef Wittschieber D, Schulz R, Vieth V et al (2014) The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study. Forensic Sci Med Pathol 10:163–169CrossRef
8.
go back to reference Zhang K, Chen XG, Zhao H, Dong XA, Deng ZH (2015) Forensic age estimation using thin-slice multidetector CT of the clavicular epiphyses among adolescent western Chinese. J Forensic Sci 60:675–678CrossRef Zhang K, Chen XG, Zhao H, Dong XA, Deng ZH (2015) Forensic age estimation using thin-slice multidetector CT of the clavicular epiphyses among adolescent western Chinese. J Forensic Sci 60:675–678CrossRef
9.
go back to reference Wittschieber D, Ottow C, Vieth V et al (2015) Projection radiography of the clavicle: still recommendable for forensic age diagnostics in living individuals? Int J Legal Med 129:187–193CrossRef Wittschieber D, Ottow C, Vieth V et al (2015) Projection radiography of the clavicle: still recommendable for forensic age diagnostics in living individuals? Int J Legal Med 129:187–193CrossRef
10.
go back to reference Cameriere R, Giuliodori A, Zampi M et al (2015) Age estimation in children and young adolescents for forensic purposes using fourth cervical vertebra (C4). Int J Legal Med 129:347–355CrossRef Cameriere R, Giuliodori A, Zampi M et al (2015) Age estimation in children and young adolescents for forensic purposes using fourth cervical vertebra (C4). Int J Legal Med 129:347–355CrossRef
11.
go back to reference Nagaoka T, Kawakubo Y (2015) Using the petrous part of the temporal bone to estimate fetal age at death. Forensic Sci Int 248(188):e181–e187 Nagaoka T, Kawakubo Y (2015) Using the petrous part of the temporal bone to estimate fetal age at death. Forensic Sci Int 248(188):e181–e187
12.
go back to reference de Oliveira FT, Soares MQ, Sarmento VA, Rubira CM, Lauris JR, Rubira-Bullen IR (2015) Mandibular ramus length as an indicator of chronological age and sex. Int J Legal Med 129:195–201CrossRef de Oliveira FT, Soares MQ, Sarmento VA, Rubira CM, Lauris JR, Rubira-Bullen IR (2015) Mandibular ramus length as an indicator of chronological age and sex. Int J Legal Med 129:195–201CrossRef
13.
go back to reference Lewis AJ, Boaz K, Nagesh KR et al (2015) Demirjian’s method in the estimation of age: a study on human third molars. J Forensic Dent Sci 7:153–157CrossRef Lewis AJ, Boaz K, Nagesh KR et al (2015) Demirjian’s method in the estimation of age: a study on human third molars. J Forensic Dent Sci 7:153–157CrossRef
14.
go back to reference Talabani RM, Baban MT, Mahmood MA (2015) Age estimation using lower permanent first molars on a panoramic radiograph: a digital image analysis. J Forensic Dent Sci 7:158–162CrossRef Talabani RM, Baban MT, Mahmood MA (2015) Age estimation using lower permanent first molars on a panoramic radiograph: a digital image analysis. J Forensic Dent Sci 7:158–162CrossRef
15.
go back to reference Ge ZP, Ma RH, Li G, Zhang JZ, Ma XC (2015) Age estimation based on pulp chamber volume of first molars from cone-beam computed tomography images. Forensic Sci Int 253(133):e131–e137 Ge ZP, Ma RH, Li G, Zhang JZ, Ma XC (2015) Age estimation based on pulp chamber volume of first molars from cone-beam computed tomography images. Forensic Sci Int 253(133):e131–e137
16.
go back to reference Scoles PV, Salvagno R, Villalba K, Riew D (1988) Relationship of iliac crest maturation to skeletal and chronologic age. J Pediatr Orthop 8:639–644CrossRef Scoles PV, Salvagno R, Villalba K, Riew D (1988) Relationship of iliac crest maturation to skeletal and chronologic age. J Pediatr Orthop 8:639–644CrossRef
17.
go back to reference Wittschieber D, Vieth V, Domnick C, Pfeiffer H, Schmeling A (2013) The iliac crest in forensic age diagnostics: evaluation of the apophyseal ossification in conventional radiography. Int J Legal Med 127:473–479CrossRef Wittschieber D, Vieth V, Domnick C, Pfeiffer H, Schmeling A (2013) The iliac crest in forensic age diagnostics: evaluation of the apophyseal ossification in conventional radiography. Int J Legal Med 127:473–479CrossRef
18.
go back to reference Wittschieber D, Vieth V, Wierer T, Pfeiffer H, Schmeling A (2013) Cameriere’s approach modified for pelvic radiographs: a novel method to assess apophyseal iliac crest ossification for the purpose of forensic age diagnostics. Int J Legal Med 127:825–829CrossRef Wittschieber D, Vieth V, Wierer T, Pfeiffer H, Schmeling A (2013) Cameriere’s approach modified for pelvic radiographs: a novel method to assess apophyseal iliac crest ossification for the purpose of forensic age diagnostics. Int J Legal Med 127:825–829CrossRef
19.
go back to reference Eich GF, Babyn P, Giedion A (1992) Pediatric pelvis: radiographic appearance in various congenital disorders. Radiographics 12:467–484CrossRef Eich GF, Babyn P, Giedion A (1992) Pediatric pelvis: radiographic appearance in various congenital disorders. Radiographics 12:467–484CrossRef
20.
go back to reference Buckberry JL, Chamberlain AT (2002) Age estimation from the auricular surface of the ilium: a revised method. Am J Phys Anthropol 119:231–239CrossRef Buckberry JL, Chamberlain AT (2002) Age estimation from the auricular surface of the ilium: a revised method. Am J Phys Anthropol 119:231–239CrossRef
21.
go back to reference Hao D, Xiren X, Rubiao P (1996) The evaluation of the apophyseal ossification in conventional radiography in Hai Nan Han Group. Forensic Science and Technology 6:24–26 Hao D, Xiren X, Rubiao P (1996) The evaluation of the apophyseal ossification in conventional radiography in Hai Nan Han Group. Forensic Science and Technology 6:24–26
22.
go back to reference Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276CrossRef Schmidt S, Schmeling A, Zwiesigk P, Pfeiffer H, Schulz R (2011) Sonographic evaluation of apophyseal ossification of the iliac crest in forensic age diagnostics in living individuals. Int J Legal Med 125:271–276CrossRef
23.
go back to reference Zhang K, Dong XA, Chen XG, Li Y, Deng ZH (2015) Forensic age estimation through evaluation of the apophyseal ossification of the iliac crest in Western Chinese. Forensic Sci Int 252(192):e191–e195 Zhang K, Dong XA, Chen XG, Li Y, Deng ZH (2015) Forensic age estimation through evaluation of the apophyseal ossification of the iliac crest in Western Chinese. Forensic Sci Int 252(192):e191–e195
24.
go back to reference Zhang K, Dong XA, Chen XG, Li Y, Deng ZH (2014) The ossification of the ischial tuberosity for forensic age diagnostics in conventional radiography. Australian Journal of Forensic Sciences 46:455–462CrossRef Zhang K, Dong XA, Chen XG, Li Y, Deng ZH (2014) The ossification of the ischial tuberosity for forensic age diagnostics in conventional radiography. Australian Journal of Forensic Sciences 46:455–462CrossRef
25.
go back to reference Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A (2010) Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med 124:321–325CrossRef Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A (2010) Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med 124:321–325CrossRef
26.
go back to reference Kreitner KF, Schweden F, Schild HH, Riepert T, Nafe B (1997) Computerized tomography of the epiphyseal union of the medial clavicle: an auxiliary method of age determination during adolescence and the 3d decade of life? Röfo 166:481–486PubMed Kreitner KF, Schweden F, Schild HH, Riepert T, Nafe B (1997) Computerized tomography of the epiphyseal union of the medial clavicle: an auxiliary method of age determination during adolescence and the 3d decade of life? Röfo 166:481–486PubMed
27.
go back to reference Schmidt S, Schiborr M, Pfeiffer H, Schmeling A, Schulz R (2013) Sonographic examination of the apophysis of the iliac crest for forensic age estimation in living persons. Sci Justice 53:395–401CrossRef Schmidt S, Schiborr M, Pfeiffer H, Schmeling A, Schulz R (2013) Sonographic examination of the apophysis of the iliac crest for forensic age estimation in living persons. Sci Justice 53:395–401CrossRef
28.
go back to reference Wittschieber D, Vieth V, Timme M, Dvorak J, Schmeling A (2014) Magnetic resonance imaging of the iliac crest: age estimation in under-20 soccer players. Forensic Sci Med Pathol 10:198–202CrossRef Wittschieber D, Vieth V, Timme M, Dvorak J, Schmeling A (2014) Magnetic resonance imaging of the iliac crest: age estimation in under-20 soccer players. Forensic Sci Med Pathol 10:198–202CrossRef
29.
go back to reference Ji L, Terazawa K, Tsukamoto T, Haga K (1994) Estimation of age from epiphyseal union degrees of the sternal end of the clavicle. Hokkaido Igaky Zasshi 69:104–111 Ji L, Terazawa K, Tsukamoto T, Haga K (1994) Estimation of age from epiphyseal union degrees of the sternal end of the clavicle. Hokkaido Igaky Zasshi 69:104–111
30.
go back to reference O’Connor JE, Coyle J, Bogue C, Spence LD, Last J (2014) Age prediction formulae from radiographic assessment of skeletal maturation at the knee in an Irish population. Forensic Sci Int 234(188):e181–e188 O’Connor JE, Coyle J, Bogue C, Spence LD, Last J (2014) Age prediction formulae from radiographic assessment of skeletal maturation at the knee in an Irish population. Forensic Sci Int 234(188):e181–e188
31.
go back to reference Aboshi H, Takahashi T, Komuro T (2010) Age estimation using microfocus X-ray computed tomography of lower premolars. Forensic Sci Int 200:35–40CrossRef Aboshi H, Takahashi T, Komuro T (2010) Age estimation using microfocus X-ray computed tomography of lower premolars. Forensic Sci Int 200:35–40CrossRef
32.
go back to reference Van Vlierberghe M, Boltacz-Rzepkowska E, Van Langenhove L et al (2010) A comparative study of two different regression methods for radiographs in Polish youngsters estimating chronological age on third molars. Forensic Sci Int 201:86–94CrossRef Van Vlierberghe M, Boltacz-Rzepkowska E, Van Langenhove L et al (2010) A comparative study of two different regression methods for radiographs in Polish youngsters estimating chronological age on third molars. Forensic Sci Int 201:86–94CrossRef
Metadata
Title
Age estimation based on pelvic ossification using regression models from conventional radiography
Authors
Kui Zhang
Xiao-ai Dong
Fei Fan
Zhen-hua Deng
Publication date
01-07-2016
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Legal Medicine / Issue 4/2016
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-016-1383-7

Other articles of this Issue 4/2016

International Journal of Legal Medicine 4/2016 Go to the issue