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Published in: European Radiology 4/2011

01-04-2011 | Forensic Medicine

Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach

Authors: Elke Hillewig, J. De Tobel, O. Cuche, P. Vandemaele, M. Piette, K. Verstraete

Published in: European Radiology | Issue 4/2011

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Abstract

Objectives

The use of 3T magnetic resonance imaging (MRI) of the clavicle in forensic bone age determination was prospectively examined and compared with plain radiography.

Methods

Four MRI sequences and three radiographs of 121 healthy subjects between 11 and 30 were studied by two observers.

Results

The number of images assessable for bone age determination was lower for plain radiography (PA: 68.7%; oblique: 97.5%) compared with MRI (VIBE: 99.0%). Concerning the subjective level of difficulty to assess bone age, the observers found it easier to assess bone age on MRI than on radiography. The developmental stages of the clavicle, as used on plain radiography, were transferable to MRI. Especially the VIBE gradient echo sequence provided an excellent depiction of the growth cartilage and ossification centre with a slice thickness of 0.9 mm and only a 4-min acquisition time. When the developmental stages were assigned, less variability between the observers was seen on MRI, compared with plain radiography.

Conclusion

We conclude that 3T MRI provides high resolution, cross-sectional images of the maturation of the clavicle without ionising radiation in a very short time, allowing more accurate determination of bone age than plain radiography.
Literature
2.
go back to reference Schmeling A, Kaatsch HJ, Marre B et al (2001) Empfehlungen für die Alterdiagnostik bei Lebenden im Strafverfahren. Rechtsmedizin 11:1–3CrossRef Schmeling A, Kaatsch HJ, Marre B et al (2001) Empfehlungen für die Alterdiagnostik bei Lebenden im Strafverfahren. Rechtsmedizin 11:1–3CrossRef
3.
go back to reference Schmeling A, Reisinger W, Geserick G, Olze A (2006) Age estimation of unaccompanied minors—Part I: general considerations. Forensic Sci Int 159:S61–S64PubMedCrossRef Schmeling A, Reisinger W, Geserick G, Olze A (2006) Age estimation of unaccompanied minors—Part I: general considerations. Forensic Sci Int 159:S61–S64PubMedCrossRef
5.
go back to reference Lockemann U, Fuhrmann A, Puschel K, Schmeling A, Geserick G (2004) Empfehlungen für die Alterdiagnostik bei Jugendlichen und jungen Erwachsenen ausserhalb des Strafverfahrens. Rechtsmedizin 14:123–125CrossRef Lockemann U, Fuhrmann A, Puschel K, Schmeling A, Geserick G (2004) Empfehlungen für die Alterdiagnostik bei Jugendlichen und jungen Erwachsenen ausserhalb des Strafverfahrens. Rechtsmedizin 14:123–125CrossRef
7.
go back to reference Dutch Ministry of Justice, Netherlands Forensic Institute (2008) Age Investigation Protocol. Dutch Ministry of Justice and the Netherlands Forensic Institute, The Netherlands. Available via http://www.forensischinstituut.nl. Accessed 3 June 2010 Dutch Ministry of Justice, Netherlands Forensic Institute (2008) Age Investigation Protocol. Dutch Ministry of Justice and the Netherlands Forensic Institute, The Netherlands. Available via http://​www.​forensischinstit​uut.​nl. Accessed 3 June 2010
8.
go back to reference Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Leg Med 118:5–8. doi:10.1007/s00414-003-0404-5 CrossRef Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Leg Med 118:5–8. doi:10.​1007/​s00414-003-0404-5 CrossRef
9.
go back to reference Ludescher B, Martirosian P, Lenk S, Machann J, Dammann F, Schick F, Claussen C, Schlemmer H (2005) High-resolution magnetic resonance imaging of trabecular bone in the wrist at 3T: initial results. Acta Radiol 46:306–305. doi:10.1080/02841850510021076 PubMedCrossRef Ludescher B, Martirosian P, Lenk S, Machann J, Dammann F, Schick F, Claussen C, Schlemmer H (2005) High-resolution magnetic resonance imaging of trabecular bone in the wrist at 3T: initial results. Acta Radiol 46:306–305. doi:10.​1080/​0284185051002107​6 PubMedCrossRef
11.
go back to reference Bauer J, Krause S, Ross C, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link T (2006) Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology 241:399–406PubMedCrossRef Bauer J, Krause S, Ross C, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link T (2006) Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology 241:399–406PubMedCrossRef
13.
go back to reference Kreitner KF, Schweden FJ, Riepert T, Nafe B, Thelen M (1998) Bone age determination based on the study of the medial extremity of the clavicle. Eur Radiol 8:1116–1122PubMedCrossRef Kreitner KF, Schweden FJ, Riepert T, Nafe B, Thelen M (1998) Bone age determination based on the study of the medial extremity of the clavicle. Eur Radiol 8:1116–1122PubMedCrossRef
14.
go back to reference Flecker H (1942) Time of appearance and fusion of ossification centers as observed by roentgenographic methods. AJR Am J Roentgenol 47:97–159 Flecker H (1942) Time of appearance and fusion of ossification centers as observed by roentgenographic methods. AJR Am J Roentgenol 47:97–159
15.
go back to reference Destouet JM, Gilula LA, Murphy WA, Sagel SS (1981) Computed-tomography of the sternoclavicular joint and sternum. Radiology 138:123–128PubMed Destouet JM, Gilula LA, Murphy WA, Sagel SS (1981) Computed-tomography of the sternoclavicular joint and sternum. Radiology 138:123–128PubMed
16.
go back to reference Lucet L, LeLoet X, Menard JF et al (1996) Computed tomography of the normal sternoclavicular joint. Skeletal Radiol 25:237–241PubMedCrossRef Lucet L, LeLoet X, Menard JF et al (1996) Computed tomography of the normal sternoclavicular joint. Skeletal Radiol 25:237–241PubMedCrossRef
17.
go back to reference Robben S (2004) Uitspraak rechtbank ’s Gravenhage inzake leeftijdsonderzoek. Memorad 9:14–15 Robben S (2004) Uitspraak rechtbank ’s Gravenhage inzake leeftijdsonderzoek. Memorad 9:14–15
18.
go back to reference Ramsthaler F, Proschek P, Betz W, Verhoff MA (2009) How reliable are the risk estimates for X-ray examinations in forensic age estimations? A safety update. Int J Leg Med 123:199–204. doi:10.1007/s00414-009-0322-2 CrossRef Ramsthaler F, Proschek P, Betz W, Verhoff MA (2009) How reliable are the risk estimates for X-ray examinations in forensic age estimations? A safety update. Int J Leg Med 123:199–204. doi:10.​1007/​s00414-009-0322-2 CrossRef
19.
go back to reference Richardson DB, Wing S, Hoffmann W (2001) Cancer risk from low-level ionizing radiation: the role of age at exposure. State Art Rev Occup Med 16:191–218 Richardson DB, Wing S, Hoffmann W (2001) Cancer risk from low-level ionizing radiation: the role of age at exposure. State Art Rev Occup Med 16:191–218
20.
go back to reference Brenner DJ, Elliston CD, Hall EJ, Berdon WE (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR Am J Roentgenol 176:289–296PubMed Brenner DJ, Elliston CD, Hall EJ, Berdon WE (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR Am J Roentgenol 176:289–296PubMed
21.
go back to reference Jung H (2000) Strahlenrisiken durch Röntgenuntersuchungen zur Alterschätzung im strafverfahren. Fortschr Röntgenstr 172:553–556CrossRef Jung H (2000) Strahlenrisiken durch Röntgenuntersuchungen zur Alterschätzung im strafverfahren. Fortschr Röntgenstr 172:553–556CrossRef
22.
go back to reference Schmeling A, Reisinger W, Wormanns D, Geserick G (2000) Strahlenexposition bei Röntgenuntersuchungen zur forensischen Alterschätzung Lebender. Rechtsmedizin 10:135–137CrossRef Schmeling A, Reisinger W, Wormanns D, Geserick G (2000) Strahlenexposition bei Röntgenuntersuchungen zur forensischen Alterschätzung Lebender. Rechtsmedizin 10:135–137CrossRef
23.
go back to reference Okkalides D, Fotakis M (1994) Patient effective dose resulting from radiographic examinations. Br J Radiol 67:564–572PubMedCrossRef Okkalides D, Fotakis M (1994) Patient effective dose resulting from radiographic examinations. Br J Radiol 67:564–572PubMedCrossRef
24.
go back to reference Jurik AG, Jensen LC, Hansen J (1996) Radiation dose by spiral CT and conventional tomography of the sternoclavicular joints and the manubrium sterni. Skeletal Radiol 25:467–470PubMedCrossRef Jurik AG, Jensen LC, Hansen J (1996) Radiation dose by spiral CT and conventional tomography of the sternoclavicular joints and the manubrium sterni. Skeletal Radiol 25:467–470PubMedCrossRef
26.
go back to reference Quirmbach F, Ramsthaler F, Verhoff MA (2009) Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years. Int J Leg Med 123:241–245. doi:10.1007/s00414-009-0335-x CrossRef Quirmbach F, Ramsthaler F, Verhoff MA (2009) Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years. Int J Leg Med 123:241–245. doi:10.​1007/​s00414-009-0335-x CrossRef
Metadata
Title
Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach
Authors
Elke Hillewig
J. De Tobel
O. Cuche
P. Vandemaele
M. Piette
K. Verstraete
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
European Radiology / Issue 4/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1978-1

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