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01-10-2010 | Pediatric

Low-dose prospective ECG-triggering dual-source CT angiography in infants and children with complex congenital heart disease: first experience

Authors: Zhaoping Cheng, Ximing Wang, Yanhua Duan, Lebin Wu, Dawei Wu, Baoting Chao, Cheng Liu, Zhuodong Xu, Hongxin Li, Fei Liang, Jian Xu, Jiuhong Chen

Published in: European Radiology | Issue 10/2010

Abstract

Objective:

To explore the clinical value of low-dose prospective ECG-triggering dual-source CT (DSCT) angiography in infants and children with complex congenital heart disease (CHD) compared with transthoracic echocardiography (TTE).

Methods:

Thirty-five patients (mean age: 16 months, range: 2 months to 6 years; male 15; mean weight: 12 kg) underwent low-dose prospective ECG-triggering DSCT angiography and TTE. Surgeries were performed in 29 patients, and conventional cardiac angiography (CCA) was performed in 8 patients. The accuracy was calculated based on the surgical and/or CCA findings. The overall imaging quality was evaluated on a five-point scale.

Results:

A total of 146 separate cardiovascular deformities were confirmed. DSCT missed three atrial septal defects and a patent ductus arteriosus. The accuracy of DSCT angiography and TTE was 97.3% (142/146) and 92.5% (135/146), respectively. Overall test parameters for DSCT angiography and TTE were similar (sensitivity, 97.3% vs 92.5%; specificity, 99.8% vs 99.8%). The average subjective image quality score was 4.3 ± 0.7. The mean effective dose was 0.38 ± 0.09 mSv.

Conclusions:

Prospective ECG-triggering DSCT angiography with a very low effective radiation dose allows the accurate diagnosis of anomalies in infants and children with complex CHD compared with TTE. It has great promise to become a commonly used second-line technique for complex CHD.

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Title: Low-dose prospective ECG-triggering dual-source CT angiography in infants and children with complex congenital heart disease: first experience
Authors: Zhaoping Cheng
Ximing Wang
Yanhua Duan
Lebin Wu
Dawei Wu
Baoting Chao
Cheng Liu
Zhuodong Xu
Hongxin Li
Fei Liang
Jian Xu
Jiuhong Chen
Publication date: 01-10-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 10/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1822-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Low-dose prospective ECG-triggering dual-source CT angiography in infants and children with complex congenital heart disease: first experience

Abstract

Objective:

Methods:

Results:

Conclusions:

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective:

Methods:

Results:

Conclusions:

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