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Published in: European Radiology 10/2010

01-10-2010 | Experimental

Assessment of liver steatosis in chicken by using acoustic radiation force impulse imaging: preliminary results

Authors: Florentina Guzmán Aroca, Ignacio Ayala, Laura Serrano, Juan D. Berná-Serna, María T. Castell, Bartolomé García-Pérez, Manuel Reus

Published in: European Radiology | Issue 10/2010

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Abstract

Objective

To evaluate acoustic radiation force impulse (ARFI) imaging as a non-invasive tool for quantification of the grades of liver steatosis in chickens.

Methods

We used two different diets: a standard diet (SD group) and a hyperlipidaemic diet (HD group). The ARFI technique was performed in all the animals in the right hepatic lobe and shear wave velocity (SWV) was measured and expressed in metres per second (m/s). Plasma lipid levels were analysed. Steatosis was quantified by using semiquantitative analysis. Statistical analysis was used and Pearson’s correlation coefficient was calculated.

Results

Mean SWV was 0.94 ± 0.16 m/s (range 0.8–1.3 m/s) in the SD group and 1.91 ± 0.25 m/s (range 1.3–2.2 m/s) in the HD group (p < 0.001). The lowest SWVs (≤1.3 m/s) corresponded to the chickens in the SD group, with 100% of the animals returning a score of 0, whereas the range of SWV in the HD group chickens was between 1.6 and 2.2 m/s. A substantial correlation was observed between SWVs with histological semiquantitative analysis of steatosis (r = 0.85, p < 0.001).

Conclusion

ARFI imaging is a non-invasive diagnostic tool that allows discrimination between the grades of liver steatosis in chickens.
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Metadata
Title
Assessment of liver steatosis in chicken by using acoustic radiation force impulse imaging: preliminary results
Authors
Florentina Guzmán Aroca
Ignacio Ayala
Laura Serrano
Juan D. Berná-Serna
María T. Castell
Bartolomé García-Pérez
Manuel Reus
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
European Radiology / Issue 10/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1808-5

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