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Published in:

01-08-2013 | Review

Bone mineralization: from tissue to crystal in normal and pathological contexts

Authors: Y. Bala, D. Farlay, G. Boivin

Published in: Osteoporosis International | Issue 8/2013

Abstract

Bone is a complex and structured material; its mechanical behavior results from an interaction between the properties of each level of its structural hierarchy. The degree of mineralization of bone (bone density measured at tissue level) and the characteristics of the mineral deposited (apatite crystals) are major determinants of bone strength. Bone remodeling activity acts as a regulator of the degree of mineralization and of the distribution of mineral at the tissue level, directly impacting bone mechanical properties. Recent findings have highlighted the need to understand the underlying process occurring at the nanostructure level that may be independent of bone remodeling itself. A more global comprehension of bone qualities will need further works designed to characterize what are the consequences on whole bone strength of changes at nano- or microstructure levels relative to each other.

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Title: Bone mineralization: from tissue to crystal in normal and pathological contexts
Authors: Y. Bala
D. Farlay
G. Boivin
Publication date: 01-08-2013
Publisher: Springer London
Published in: Osteoporosis International / Issue 8/2013
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-012-2228-y

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Springer Medicine

Bone mineralization: from tissue to crystal in normal and pathological contexts

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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