Issue 1/2007
Content (70 Articles)
Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation
Jiaqiang Ren, Ping Jin, Ena Wang, Eric Liu, David M Harlan, Xin Li, David F Stroncek
Clinical relevance of Neutral Endopeptidase (NEP/CD10) in melanoma
Elsa F Velazquez, Molly Yancovitz, Anna Pavlick, Russell Berman, Richard Shapiro, Dusan Bogunovic, David O'Neill, Yi-Lo Yu, Joanna Spira, Paul J Christos, Xi Kathy Zhou, Madhu Mazumdar, David M Nanus, Leonard Liebes, Nina Bhardwaj, David Polsky, Iman Osman
Usefulness of cancer-testis antigens as biomarkers for the diagnosis and treatment of hepatocellular carcinoma
Fabio Grizzi, Barbara Franceschini, Cody Hamrick, Eldo E Frezza, Everardo Cobos, Maurizio Chiriva-Internati
Therapeutic use of Aldara™ in chronic myeloid leukemia
Annette M Marleau, Jeffrey H Lipton, Neil H Riordan, Thomas E Ichim
Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells
Venky Ramakrishna, John P Vasilakos, Joseph D Tario Jr, Marc A Berger, Paul K Wallace, Tibor Keler
The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization
Harriet M Kluger, Mary M McCarthy, Ayesha B Alvero, Mario Sznol, Stephan Ariyan, Robert L Camp, David L Rimm, Gil Mor
Immune-mediated changes in actinic keratosis following topical treatment with imiquimod 5% cream
Abel Torres, Leslie Storey, Makala Anders, Richard L Miller, Barbara J Bulbulian, Jizhong Jin, Shalini Raghavan, James Lee, Herbert B Slade, Woubalem Birmachu
Cord blood in regenerative medicine: do we need immune suppression?
Neil H Riordan, Kyle Chan, Annette M Marleau, Thomas E Ichim
CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV
Dorothy E Lewis, Kimber L Gross, Martine M Diez, Maria L Martinez, Helen N Lukefahr, Claudia A Kozinetz, Roberto C Arduino
Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models
Xinmei Zhu, Fumihiko Nishimura, Kotaro Sasaki, Mitsugu Fujita, Jill E Dusak, Junichi Eguchi, Wendy Fellows-Mayle, Walter J Storkus, Paul R Walker, Andres M Salazar, Hideho Okada
Gene expression profiling of cutaneous wound healing
Kavita Deonarine, Monica C Panelli, Mitchell E Stashower, Ping Jin, Kina Smith, Herbert B Slade, Christopher Norwood, Ena Wang, Francesco M Marincola, David F Stroncek
Telomerase immunity from bench to bedside: round one
Xochtil Cortez-Gonzalez, Maurizio Zanetti
Calcium Sulfate and Platelet-Rich Plasma make a novel osteoinductive biomaterial for bone regeneration
Giuseppe Intini, Sebastiano Andreana, Francesco E Intini, Robert J Buhite, Libuse A Bobek
Tumor-specific T cells signal tumor destruction via the lymphotoxin β receptor
Hauke Winter, Natasja K van den Engel, Christian H Poehlein, Rudolf A Hatz, Bernard A Fox, Hong-Ming Hu
Safety and efficacy of Y-90 microsphere treatment in patients with primary and metastatic liver cancer: The tumor selectivity of the treatment as a function of tumor to liver flow ratio
Seza A Gulec, Geraldine Mesoloras, William A Dezarn, Patrick McNeillie, Andrew S Kennedy
Specific targeting of whole lymphoma cells to dendritic cells ex vivo provides a potent antitumor vaccine
Christian Adam, Josef Mysliwietz, Ralph Mocikat
CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects
Stefanie L Slezak, Maria Bettinotti, Silvia Selleri, Sharon Adams, Francesco M Marincola, David F Stroncek
Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70
Anke Zobywalski, Miran Javorovic, Bernhard Frankenberger, Heike Pohla, Elisabeth Kremmer, Iris Bigalke, Dolores J Schendel
Monocyte-derived dendritic cells loaded with a mixture of apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
Erika M von Euw, María M Barrio, David Furman, Michele Bianchini, Estrella M Levy, Cassian Yee, Yongqing Li, Rosa Wainstok, José Mordoh
Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax®
Marc Mansour, Bill Pohajdak, W Martin Kast, Antar Fuentes-Ortega, Ella Korets-Smith, Genevieve M Weir, Robert G Brown, Pirouz Daftarian
In support of descriptive studies; relevance to translational research
Francesco M Marincola
Associations between HLA Class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians
Xin Li, Nahla Ghandri, Daniela Piancatelli, Sharon Adams, Deborah Chen, Fu-Meei Robbins, Ena Wang, Alessandro Monaco, Silvia Selleri, Noureddine Bouaouina, David Stroncek, Domenico Adorno, Lotfi Chouchane, Francesco M Marincola
CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia
Dianne Pulte, Kim E Olson, M Johan Broekman, Naziba Islam, Harold S Ballard, Richard R Furman, Ashley E Olson, Aaron J Marcus
Potency analysis of cellular therapies: the emerging role of molecular assays
David F Stroncek, Ping Jin, Ena Wang, Betsy Jett
Transfusion-transmitted infections
Florian Bihl, Damiano Castelli, Francesco Marincola, Roger Y Dodd, Christian Brander
Rejection of large HPV-16 expressing tumors in aged mice by a single immunization of VacciMax® encapsulated CTL/T helper peptides
Pirouz M Daftarian, Marc Mansour, Bill Pohajdak, Antar Fuentes-Ortega, Ella Korets-Smith, Lisa MacDonald, Genevieve Weir, Robert G Brown, W Martin Kast
Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis
Francesca Chamian, Shao-Lee Lin, Edmund Lee, Toyoko Kikuchi, Patricia Gilleaudeau, Mary Sullivan-Whalen, Irma Cardinale, Artemis Khatcherian, Inna Novitskaya, Knut M Wittkowski, James G Krueger, Michelle A Lowes
Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins : Implication for microbicide development
Hela Saïdi, Nadine Nasreddine, Mohammad-Ali Jenabian, Maxime Lecerf, Dominique Schols, Corinne Krief, Jan Balzarini, Laurent Bélec
Adoptively transferred human lung tumor specific cytotoxic T cells can control autologous tumor growth and shape tumor phenotype in a SCID mouse xenograft model
Ezogelin Oflazoglu, Mark Elliott, Hiroshi Takita, Soldano Ferrone, Robert A Henderson, Elizabeth A Repasky
Stem Cell Therapy for Autism
Thomas E Ichim, Fabio Solano, Eduardo Glenn, Frank Morales, Leonard Smith, George Zabrecky, Neil H Riordan
Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in humans
Johann Zdolsek, John W Eaton, Liping Tang
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
Samuel E DePrimo, Carlo L Bello, John Smeraglia, Charles M Baum, Dominic Spinella, Brian I Rini, M Dror Michaelson, Robert J Motzer
Serum proteomic analysis focused on fibrosis in patients with hepatitis C virus infection
Ian R White, Keyur Patel, William T Symonds, Anouk Dev, Philip Griffin, Nikos Tsokanas, Mark Skehel, Chiang Liu, Amany Zekry, Paul Cutler, Mahanandeeshwar Gattu, Don C Rockey, Michelle M Berrey, John G McHutchison
Investigation of HIFU-induced anti-tumor immunity in a murine tumor model
Zhenlin Hu, Xiao Yi Yang, Yunbo Liu, Georgy N Sankin, Eric C Pua, Michael A Morse, H Kim Lyerly, Timothy M Clay, Pei Zhong
Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells
Sara Deola, Samantha Scaramuzza, Roberto Sciarretta Birolo, Massimiliano Cergnul, Francesca Ficara, Jonathan Dando, Claudia Voena, Sergio Vai, Marta Monari, Enrico Pogliani, Gianmarco Corneo, Jacopo Peccatori, Silvia Selleri, Claudio Bordignon, Maria Grazia Roncarolo, Alessandro Aiuti, Marco Bregni
Haplotype of gene Nedd4 binding protein 2 associated with sporadic nasopharyngeal carcinoma in the Southern Chinese population
Mei-Zhen Zheng, Hai-De Qin, Xing-Juan Yu, Ru-Hua Zhang, Li-Zhen Chen, Qi-Sheng Feng, Yi-Xin Zeng
Absence of a relationship between immunophenotypic and colony enumeration analysis of endothelial progenitor cells in clinical haematopoietic cell sources
Olga Tura, G Robin Barclay, Huw Roddie, John Davies, Marc L Turner
Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma
David P Mangiameli, Joseph A Blansfield, Stephan Kachala, Dominique Lorang, Peter H Schafer, George W Muller, David I Stirling, Steven K Libutti
Semi-allogeneic vaccine for T-cell lymphoma
Jin Yu, Mark S Kindy, Sebastiano Gattoni-Celli
The Excellence in Translational Medicine Award 2006–07
Richard J Ablin, Yi-Xin Zeng
Application of Atomic Dielectric Resonance Spectroscopy for the screening of blood samples from patients with clinical variant and sporadic CJD
Timothy J Fagge, G Robin Barclay, G Colin Stove, Gordon Stove, Michael J Robinson, Mark W Head, James W Ironside, Marc L Turner
Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2
Michael A Morse, Amy Hobeika, Takuya Osada, Donna Niedzwiecki, Paul Kelly Marcom, Kimberly L Blackwell, Carey Anders, Gayathri R Devi, H Kim Lyerly, Timothy M Clay
Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response
Dominik Rüttinger, Natasja K van den Engel, Hauke Winter, Marcus Schlemmer, Heike Pohla, Stefanie Grützner, Beate Wagner, Dolores J Schendel, Bernard A Fox, K-W Jauch, Rudolf A Hatz
The mast cell integrates the splanchnic and systemic inflammatory response in portal hypertension
María-Angeles Aller, Jorge-Luis Arias, Jaime Arias
A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy
Louise R Rodino-Klapac, Paul ML Janssen, Chrystal L Montgomery, Brian D Coley, Louis G Chicoine, K Reed Clark, Jerry R Mendell
Monocyte derived dendritic cells generated by IFN-α acquire mature dendritic and natural killer cell properties as shown by gene expression analysis
Mark Korthals, Nancy Safaian, Ralf Kronenwett, Dagmar Maihöfer, Matthias Schott, Claudia Papewalis, Elena Diaz Blanco, Meike Winter, Akos Czibere, Rainer Haas, Guido Kobbe, Roland Fenk
Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles
Ying Jiang, David L Gerhold, Daniel J Holder, David J Figueroa, Wendy J Bailey, Ping Guan, Thomas R Skopek, Frank D Sistare, Joseph F Sina
Patterns of tumor response in canine and feline cancer patients treated with electrochemotherapy: preclinical data for the standardization of this treatment in pets and humans
Enrico P Spugnini, Feliciano Baldi, Pasquale Mellone, Florinda Feroce, Alfredo D'Avino, Francesco Bonetto, Bruno Vincenzi, Gennaro Citro, Alfonso Baldi
The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
Michael T Buckley, Joanne Yoon, Herman Yee, Luis Chiriboga, Leonard Liebes, Gulshan Ara, Xiaozhong Qian, Dean F Bajorin, Tung-Tien Sun, Xue-Ru Wu, Iman Osman
Mycobacterium avium complex immune reconstitution inflammatory syndrome: Long term outcomes
James Riddell IV, Daniel R Kaul, Petros C Karakousis, Joel E Gallant, Jennifer Mitty, Powel H Kazanjian
Basal cytokines profile in metastatic renal cell carcinoma patients treated with subcutaneous IL-2-based therapy compared with that of healthy donors
Michele Guida, Addolorata Casamassima, Giulia Monticelli, Michele Quaranta, Giuseppe Colucci
Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines
Anna Tesei, Marco Rosetti, Paola Ulivi, Francesco Fabbri, Laura Medri, Ivan Vannini, Manlio Bolla, Dino Amadori, Wainer Zoli
Optimal ex vivo expansion of neutrophils from PBSC CD34+ cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO
Olga Tura, G Robin Barclay, Huw Roddie, John Davies, Marc L Turner
"In vitro" and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells
Giuseppe Astori, Francesca Vignati, Silvana Bardelli, Monica Tubio, Mauro Gola, Veronica Albertini, Franco Bambi, Giancarlo Scali, Damiano Castelli, Valeria Rasini, Gianni Soldati, Tiziano Moccetti
Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines
Hauke Winter, Natasja K van den Engel, Dominik Rüttinger, Jürgen Schmidt, Matthias Schiller, Christian H Poehlein, Florian Löhe, Bernard A Fox, Karl-Walter Jauch, Rudolf A Hatz, Hong-Ming Hu
Endometrial regenerative cells: A novel stem cell population
Xiaolong Meng, Thomas E Ichim, Jie Zhong, Andrea Rogers, Zhenglian Yin, James Jackson, Hao Wang, Wei Ge, Vladimir Bogin, Kyle W Chan, Bernard Thébaud, Neil H Riordan
N-myristoyltransferase: A potential novel diagnostic marker for colon cancer
Anuraag Shrivastav, Shailly Varma, Anurag Saxena, John DeCoteau, Rajendra K Sharma
Immunological intervention in human diseases
Hideki Ueno, Catherine M Hawrylowicz, Jacques Banchereau
Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer
Howard L Kaufman, Seunghee Kim-Schulze, Kelledy Manson, Gail DeRaffele, Josephine Mitcham, Kang Seok Seo, Dae Won Kim, John Marshall
A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth in vivo
Vinay Bhaskar, Dong Zhang, Melvin Fox, Pui Seto, Melanie HL Wong, Pauline E Wales, David Powers, Debra T Chao, Robert B DuBridge, Vanitha Ramakrishnan
Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival
Dirk Nagorsen, Sabine Voigt, Erika Berg, Harald Stein, Eckhard Thiel, Christoph Loddenkemper
Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis
Christoph W Michalski, Andre Gorbachevski, Mert Erkan, Carolin Reiser, Stefanie Deucker, Frank Bergmann, Thomas Giese, Markus Weigand, Nathalia A Giese, Helmut Friess, Jörg Kleeff
An epigenetic vaccine model active in the prevention and treatment of melanoma
A Nazmul H Khan, William J Magner, Thomas B Tomasi
Comments on the nonpharmaceutical interventions in New York City and Chicago during the 1918 flu pandemic
John M Barry
Phase II study of intraperitoneal recombinant interleukin-12 (rhIL-12) in patients with peritoneal carcinomatosis (residual disease < 1 cm) associated with ovarian cancer or primary peritoneal carcinoma
Renato Lenzi, Robert Edwards, Carl June, Michael V Seiden, Michael E Garcia, Michael Rosenblum, Ralph S Freedman
Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas
Hideho Okada, Frank S Lieberman, Kevin A Walter, L Dade Lunsford, Douglas S Kondziolka, Ghassan K Bejjani, Ronald L Hamilton, Alejandro Torres-Trejo, Pawel Kalinski, Quan Cai, Jennifer L Mabold, Howard D Edington, Lisa H Butterfield, Theresa L Whiteside, Douglas M Potter, S Clifford Schold Jr, Ian F Pollack
Spontaneous immune responses against glioma-associated antigens in a long term survivor with malignant glioma
Ryo Ueda, Keri L Low, Xinmei Zhu, Mitsugu Fujita, Kotaro Sasaki, Theresa L Whiteside, Lisa H Butterfield, Hideho Okada
SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden
Biagio Di Micco, Marilena Lepretti, Lidia Rota, Ilaria Quaglia, Paola Ferrazzi, Gianluca Di Micco, Pierpaolo Di Micco
Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
Jan Oldenburg, Sigrid M Kraggerud, Marianne Brydøy, Milada Cvancarova, Ragnhild A Lothe, Sophie D Fossa