This study uses the two-sample Mendelian randomization (TSMR) method to explore the causal relationships between smoking initiation (SMKI), never smoking (NSMK), past tobacco smoking (PTSMK), and the usage of antidepressants (ATD).
Negative symptoms in CHR-P people are generally not responsive to treatments and commonly related to poorer functional outcome. However, less research attention has been dedicated to Persistent Negative Symptoms (PNS), defined as clinically stable …
Authors:
Camilla Ricci, Emanuela Leuci, Emanuela Quattrone, Derna Palmisano, Pietro Pellegrini, Marco Menchetti, Simona Pupo, Lorenzo Pelizza
This study aims to investigate the altered patterns of dynamic functional network connectivity (dFNC) between deficit schizophrenia (DS) and non-deficit schizophrenia (NDS), and further explore the associations with cognitive impairments. 70 DS …
Ketamine has demonstrated rapid and sustained antidepressant effects, marking its emergence as an innovative treatment of depression. Despite the growing number of preclinical and clinical studies exploring the antidepressant effects of ketamine …
Authors:
Li-yuan Zhao, Guang-fen Zhang, Xue-jie Lou, Kenji Hashimoto, Jian-jun Yang
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition with onset in childhood and a high rate of persistence into adulthood [ 1 ]. ADHD is associated with co-occurring mental [ 1 ] and somatic conditions [ 2 ] …
Authors:
Jutta S. Mayer, Laura Kohlhas, Jacek Stermann, Juliane Medda, Geva A. Brandt, Oliver Grimm, Adam D. Pawley, Philip Asherson, Judit Palacio Sanchez, Vanesa Richarte, Douwe Bergsma, Elena D. Koch, Adrià Muntaner-Mas, Ulrich W. Ebner-Priemer, Meinhard Kieser, Wolfgang Retz, Francisco B. Ortega, Michael Colla, Jan K. Buitelaar, Jonna Kuntsi, Josep A. Ramos-Quiroga, Andreas Reif, Christine M. Freitag
Nitrous oxide (N2O) has been known since the end of the eighteenth century. Today, N2O plays a huge role as a greenhouse gas and an ozone-depleting stratospheric molecule. The main sources of anthropogenic N2O emissions are agriculture, fuel …
Authors:
Golo Kronenberg, Georgios Schoretsanitis, Erich Seifritz, Sebastian Olbrich
Open Access
13-04-2024 | Dementia | Original Paper
Criminal behavior is known to peak in people in their 20s and to decline later in life [ 1 ]. However, arrest rates in older age groups are increasing [ 1 ], and the number and proportion of older prisoners have escalated globally over the past …
Authors:
Anniina Palm, Tiina Talaslahti, Risto Vataja, Milena Ginters, Hannu Kautiainen, Henrik Elonheimo, Jaana Suvisaari, Nina Lindberg, Hannu Koponen
Reward processing is impaired in people with schizophrenia, which may begin in the clinical high-risk (CHR) for psychosis period. The Monetary Incentive Delay (MID) task has been important in understanding the neural correlates of reward …
Authors:
D. N. Pratt, M. T. Treadway, G. P. Strauss, V. A. Mittal
Open Access
08-04-2024 | COVID-19 | Original Paper
The coronavirus disease 2019 (COVID-19) pandemic was accompanied by an increase in mental health challenges including depression, stress, loneliness, and anxiety. Common genetic variants can contribute to the risk for psychiatric disorders and may …
Authors:
Alicia M. Schowe, Malvika Godara, Darina Czamara, Mazda Adli, Tania Singer, Elisabeth B. Binder
Post-COVID syndrome (PCS) is characterized by a variety of non-specific symptoms. One of the leading symptoms is fatigue. So far, there is no evidence-based causal therapy established and treatment of PCS is primarily symptom-oriented. The Clinic …
Authors:
Sarah Schmid, Christine Uecker, Antje Fröhlich, Jost Langhorst
Non-invasive brain stimulation is a promising new treatment approach for Major Depressive Disorder (MDD). Repetitive Transcranial Magnetic Stimulation (rTMS) [ 1 , 2 ], a stimulation technique aimed at the activation of local brain regions through …
Authors:
Sjoerd M. van Belkum, Esther M. Opmeer, Hanneke Geugies, Marrit K. de Boer, Robert A. Schoevers, André Aleman
Previous studies about anhedonia symptoms in bipolar depression (BD) ignored the unique role of gender on brain function. This study aims to explore the regional brain neuroimaging features of BD with anhedonia and the sex differences in these …
Anxiety and depressive disorders have overlapping symptoms and share common neurobiological pathways. Antidepressant drugs have been demonstrated to be efficacious in anxiety as well. Vice versa, it may also be promising to investigate the …
Authors:
Siegfried Kasper, Hans-Peter Volz, Hans-Jürgen Möller, Sandra Schläfke, Stephan Klement, Ion-George Anghelescu, Erich Seifritz
The individual’s mental health crisis and the COVID-19 pandemic lead to mental disorders. The transmission of the COVID-19 virus is associated with the levels of anxiety, stress, and depression in individuals, similar to other factors. Increases …
Author:
Usharani Bhimavarapu
Open Access
30-03-2024 | Breast Cancer | Original Paper
Breast cancer is one of the most prevalent and serious types of cancer globally. Previous literature has shown that women with mental illness may have an increased risk of breast cancer, however whether this risk is associated with the use of …
Exercise interventions are nowadays considered as effective add-on treatments in people with schizophrenia but are usually associated with high dropout rates. Therefore, the present study investigated potential predictors of adherence from a large …
Authors:
Rebecca Schwaiger, Isabel Maurus, Moritz Lembeck, Irina Papazova, David Greska, Susanne Muenz, Eliska Sykorova, Cristina E. Thieme, Bob O. Vogel, Sebastian Mohnke, Charlotte Huppertz, Astrid Roeh, Katriona Keller-Varady, Berend Malchow, Henrik Walter, Bernd Wolfarth, Wolfgang Wölwer, Karsten Henkel, Dusan Hirjak, Andrea Schmitt, Alkomiet Hasan, Andreas Meyer-Lindenberg, Peter Falkai, Lukas Roell
Open Access
29-03-2024 | Schizophrenia | Original Paper
After over a hundred years of research, the question whether the symptoms of schizophrenia are rather trait-like (being a relatively stable quality of individuals) or state-like (being substance to change) is still unanswered. To assess the trait …
Authors:
Jana S. Krückl, Károly Acsai, Zsófia B. Dombi, Julian Moeller, Roselind Lieb, Undine E. Lang, Ágota Barabássy, Christian G. Huber
