Prostate cancer (PC) has increasing significance: it is the second most frequent cancer diagnosis in patients and the fifth leading cause of cancer death worldwide [ 1 ]. In Japan, the incidence of PC has been growing rapidly over the past decades.
Autoimmune pancreatitis (AIP) is a distinct form of chronic pancreatitis that responds dramatically to steroids [ 1 , 2 ]. The International Consensus diagnostic criteria were proposed for AIP in 2011 and outline two distinct types: type 1, which …
Cancer stands as a prominent contributor to global mortality, accounting for nearly 10 million deaths annually [ 1 , 2 ]. Approximately one in five individuals experiences a cancer diagnosis during their lifetime, and in 2020 alone, an estimated …
In drug discovery, preclinical research using animals is an essential step in bridging between novel compounds and clinical research. In preclinical research, numerous experiments are conducted to evaluate the efficacy and safety of new drugs …
Meningiomas are the most encountered intracranial tumors [ 1 ]. Meningiomas at the skullbase or in close relation with large vascular structures, e.g., the venous sinuses, are challenging to treat. These patients often undergo multimodal treatment.
Authors:
Hanne-Rinck Jeltema, Bart R. J. van Dijken, Katalin Tamási, Gea Drost, Mart A. A. M. Heesters, Anouk van der Hoorn, Andor W. J. M. Glaudemans, J. Marc C. van Dijk
Lung cancer is the second most commonly diagnosed cancer and the leading cause of cancer-related death worldwide [ 1 ]. Adenocarcinoma is the most common histology of lung cancer, and its incidence is still rising [ 2 , 3 ]. Owing to the lack of …
Bone metastasis is common in certain advanced-stage cancers, particularly in prostate, breast, lung, thyroid, renal cell, gynecologic, and melanoma cancers. The occurrence of skeletal-related events, including pain, pathologic fractures …
Authors:
Hacı Arak, Umut Elboga, Yusuf Burak Cayirli, Aydın Aytekin
Chronic kidney disease (CKD) is a global public health problem, affecting 8–16% of the population worldwide [ 1 ]. Thirty million people, or 15% of US adults, are estimated to have CKD [ 2 ]. Patients with CKD have biochemical abnormalities of …
Authors:
Sharjeel Usmani, Najeeb Ahmed, Gopinath Gnanasegaran, Fahad Marafi, Ahmed Bani-Mustafa, Tim Van den Wyngaert
Prostate-specific membrane antigen (PSMA) is overexpressed on prostate cancer (PCa), one of the serious malignancies [ 1 – 4 ]. The expression of PSMA is also correlated with the progression of PCa [ 5 ], and PSMA is a promising target for …
Authors:
Nobuki Kazuta, Shohei Tsuchihashi, Hiroyuki Watanabe, Masahiro Ono
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from neural crest cells. Those arising from the adrenal medulla are referred to as pheochromocytomas, while those originating outside the adrenal glands from …
Prostate cancer ranks among the most prevalent malignancies in men, contributing significantly to the global cancer burden, with an estimated incidence rate of 1104 per million in 2020 [ 1 ]. Metastatic castration-resistant prostate cancer (mCRPC) …
Transarterial radioembolization (TARE), also known as selective internal radiation therapy (SIRT), is a safe and effective therapeutic approach for unresectable liver tumors, particularly hepatocellular carcinoma. The treatment strategy in TARE is …
Authors:
Nazim Coskun, Mehmet Oguz Kartal, Aysenur Sinem Kartal, Velihan Cayhan, Mustafa Ozdemir, Murat Canyigit, Elif Ozdemir
Non-small cell lung cancer (NSCLC) accounts for approximately 80–85% of lung cancer cases [ 1 ]. Distant metastasis is the leading cause of death in NSCLC, and bone is one of the common sites of distant metastasis in this type of cancer [ 2 – 5 ].
Authors:
Xia Zheng, Chunxia Li, Jing Ai, Guili Dong, Man Long, Mingyi Li, Shilin Qiu, Yanni Huang, Guangjun Yang, Tao Zhang, Zhenhui Li
Lung cancer is one of the leading causes of death from cancer worldwide and the overall 5-year survival rate of patients with lung cancer is 17.4% [ 1 , 2 ]. The standard treatment for patients with lung cancer is surgery, but radiation therapy …
Authors:
Changhwan Sung, Jungsu S. Oh, Byung Soo Park, Su Ssan Kim, Si Yeol Song, Jong Jin Lee
Neuroendocrine tumor (NET) is a heterogeneous neoplasm that originates from neuroendocrine cells and has become increasingly prevalent [ 1 , 2 ]. As NETs express high levels of somatostatin receptors (SSTRs), they can be imaged using 68 …
Cancer is a leading cause of death worldwide and a significant barrier to increasing life expectancy [ 1 ]. According to the 2019 report World Health Organization (WHO) [ 2 ], the first or second primary reason for mortality in people under 70 is …
Authors:
Seyyed Ali Hosseini, Isaac Shiri, Pardis Ghaffarian, Ghasem Hajianfar, Atlas Haddadi Avval, Milad Seyfi, Stijn Servaes, Pedro Rosa-Neto, Habib Zaidi, Mohammad Reza Ay
The spread of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has led to a global vaccination campaign [ 1 ]. Following vaccine injection into the deltoid muscle (DM), a physiological immunogenic response occurs, leading to reactive …
In 2022, the World Health Organization ranked the incidence of gastric cancer as third and fifth most in China and worldwide, respectively, with incidence and mortality rates accounting for 10.6% and 12.5% of cancer cases in China, for 5.6% and …
It is estimated that almost 1.4 million new cases of prostate cancer appear every year, making it the second most frequent cancer among men worldwide [ 1 ]. Because prostate cancer causes bone metastasis at a high rate, its control and management …
Quantitative analysis in amyloid positron emission tomography (PET) is expected to allow a continuous measure of amyloid burden, which can be used to complement dichotomous visual reads. Quantification may facilitate comparisons between different …
