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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | Herpes Virus | Case report

Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature

Authors: Mohammadreza Moslemi, Mohammadreza Ardalan, Morteza Haramshahi, Homa Mirzaei, Sahba Khosousi Sani, Ramtin Dastgir, Nima Dastgir

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

Background

Ever since the administration of early doses of COVID-19 vaccines, instances of adverse effects have been reported. Viral infections, specifically herpes simplex reinfection and coinfections, have been reported following administration of different types of vaccines. To our knowledge, there have not been any reports of herpes simplex encephalitis following administration of any type of COVID-19 vaccine to date.

Case presentation

In this article intends to report a case of herpes simplex encephalitis in a 27-year-old male patient who was vaccinated with the ChAdOx1 nCoV-19 vaccine.

Conclusions

Our study suggests a possible but very rare side effect of ChAdOx1 nCoV-19 vaccine, which requires immediate medical attention and can lead to devastating consequences if left undiagnosed and untreated.
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Metadata
Title
Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
Authors
Mohammadreza Moslemi
Mohammadreza Ardalan
Morteza Haramshahi
Homa Mirzaei
Sahba Khosousi Sani
Ramtin Dastgir
Nima Dastgir
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07186-9

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