Children born to women with epilepsy who take topiramate when pregnant are not at increased risk for autism spectrum disorders, whereas there is an increased risk with valproate.
Optimal early nutrition has a lifelong positive impact on child development. But specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can contribute to micronutrient deficiencies. Which children are at risk and need supplementation?
Completion axillary lymph node dissection can be avoided in patients with early-stage, node-negative breast cancer with one or two macrometastases, show phase 3 data.
Ovarian function suppression plays a key role in the management of breast cancer, but it comes with potentially impactful and long-lasting side effects. Counselling and proactive management of these should be considered an essential part of survivorship care.
Women with a new diagnosis of high-risk, locally advanced cervical cancer could benefit from the addition of pembrolizumab to standard chemoradiotherapy.
A case of extreme hypotension that could have been prevented or mitigated with awareness of the underlying hypothyroidism related to nivolumab treatment.
Polycystic ovary syndrome is the most common endocrinopathy in women of reproductive age, but what impact do symptoms, including psychological symptoms and cognitive alterations, have on quality of life?
Although circulating tumor DNA analysis has not been adopted as widely in gynecologic cancers as in other tumor types, new research shows promise for diagnosis, prognosis, and prediction of recurrence.
In early treatment of acute migraine pain, combined paracetamol and caffeine can benefit pediatric or older patients and those with cardiovascular comorbidities, pregnancy or breastfeeding, or poor response to trigeminal targeted therapies.
A holistic approach that takes into account all aspects of patient care – from treatment to nutrition, physical activity, and rehabilitation – could be a powerful tool to improve survival and quality of life in breast cancer.
UTIs are common in people with diabetes, but how do they compare with UTIs in people without diabetes? And what role might SGLT2 inhibitors have in the increased risk of genitourinary infections?
What specific issues need to be considered when treating female patients with acute coronary syndrome, especially those who are pregnant or post-partum?
Multisystem involvement in Turner syndrome makes the transition from pediatric to adult care very challenging. Explore guidance on all aspects of transition and referral.
A woman developed sudden painless ecchymosis (bruising) of her breast, which was thought to be related to the radiotherapy she received for early-stage breast cancer a year and a half earlier.
Amniocentesis is not routine for isolated polyhydramnios in the absence of key structural defects. But these two cases show that polyhydramnios can be caused by rare genetic conditions that benefit from early diagnosis and intervention.
Menopausal HRT may reduce the risk of type 2 diabetes developing and improve glycemic control. Individual risk factors must be considered when deciding a treatment plan.
Advances in the development of immunotherapies for ovarian cancer, such as checkpoint inhibitors, adoptive T-cell therapy, and oncolytic viruses, have expanded the treatment armamentarium and improved the prognosis of patients.
Thyroid storm is a rare endocrine emergency and its occurrence in pregnancy poses unique diagnostic and therapeutic challenges. If not treated promptly, it confers high maternal-fetal mortality and morbidity.
