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Cancer Immunology, Immunotherapy

Issue 6/2019

Content (16 Articles)

Open Access Glioblastoma Original Article

Absolute numbers of regulatory T cells and neutrophils in corticosteroid-free patients are predictive for response to bevacizumab in recurrent glioblastoma patients

Véronique Quillien, Antoine F. Carpentier, Alain Gey, Tony Avril, Eric Tartour, Floraly Sejalon, Boris Campillo-Gimenez, Elodie Vauleon

Dimethyl Fumarate Original Article

HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells

Noha Mousaad Elemam, Zaidoon Al-Jaderi, Mahmood Yaseen Hachim, Azzam A. Maghazachi

Melanoma Original Article

Autoimmune genetic risk variants as germline biomarkers of response to melanoma immune-checkpoint inhibition

Vylyny Chat, Robert Ferguson, Danny Simpson, Esther Kazlow, Rebecca Lax, Una Moran, Anna Pavlick, Dennie Frederick, Genevieve Boland, Ryan Sullivan, Antoni Ribas, Keith Flaherty, Iman Osman, Jeffrey Weber, Tomas Kirchhoff

Radiotherapy Original Article

DNA lesions correlate with lymphocyte function after selective internal radiotherapy

Aglaia Domouchtsidou, Vahé Barsegian, Stefan P. Mueller, Pavel Lobachevsky, Jan Best, Peter A. Horn, Andreas Bockisch, Monika Lindemann

Checkpoint Inhibitors Original Article

Pre-existing autoimmune disease and the risk of immune-related adverse events among patients receiving checkpoint inhibitors for cancer

Kenneth L. Kehl, Shihao Yang, Mark M. Awad, Nathan Palmer, Isaac S. Kohane, Deborah Schrag

Open Access Soft Tissue Sarcoma Original Article

An immunosuppressive macrophage profile attenuates the prognostic impact of CD20-positive B cells in human soft tissue sarcoma

Panagiotis Tsagozis, Martin Augsten, Yifan Zhang, Tian Li, Asle Hesla, Jonas Bergh, Felix Haglund, Nicholas P. Tobin, Monika Ehnman

Open Access Glioblastoma Original Article

Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma

Kim C. M. Santegoets, Paul R. Gielen, Christian Büll, Barbara M. Schulte, Esther D. Kers-Rebel, Benno Küsters, Sandra A. J. F. H. Bossman, Mark ter Laan, Pieter Wesseling, Gosse J. Adema

Heterogeneity of PD-L1 expression and CD8 tumor-infiltrating lymphocytes among subtypes of cutaneous adnexal carcinomas

Lucie Duverger, Amélie Osio, Bernard Cribier, Laurent Mortier, Adèle De Masson, Nicole Basset-Seguin, Céleste Lebbé, Maxime Battistella

Sarcoma Original Article

Immune-phenotyping of pleomorphic dermal sarcomas suggests this entity as a potential candidate for immunotherapy

Sebastian Klein, Cornelia Mauch, Svenja Wagener-Ryczek, Maximilian Schoemmel, Reinhard Buettner, Alexander Quaas, Doris Helbig

Merkel Cell Carcinoma Original Article

MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition: a case series

Selma Ugurel, Ivelina Spassova, Jonas Wohlfarth, Christina Drusio, Angela Cherouny, Anita Melior, Antje Sucker, Lisa Zimmer, Cathrin Ritter, Dirk Schadendorf, Jürgen C. Becker

Meningioma Original Article

Systemic and local immunosuppression in patients with high-grade meningiomas

Yuping D. Li, Dorina Veliceasa, Jason B. Lamano, Jonathan B. Lamano, Gurvinder Kaur, Dauren Biyashev, Craig M. Horbinski, Tim J. Kruser, Orin Bloch

Open Access Colorectal Cancer Original Article

Characterization of circulating T-, NK-, and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile

Daniëlle Krijgsman, Natasja L. de Vries, Anni Skovbo, Morten N. Andersen, Marloes Swets, Esther Bastiaannet, Alexander L. Vahrmeijer, Cornelis J. H. van de Velde, Mirjam H. M. Heemskerk, Marianne Hokland, Peter J. K. Kuppen

Open Access Kidney Cancer Clinical Trial Report

Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial

Bas D. Koster, Saskia J. A. M. Santegoets, Jorien Harting, Arnold Baars, S. Marieke van Ham, Rik J. Scheper, Erik Hooijberg, Tanja D. de Gruijl, Alfons J. M. van den Eertwegh

Kidney Cancer Correction

Correction to: Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial

Bas D. Koster, Saskia J. A. M. Santegoets, Jorien Harting, Arnold Baars, S. Marieke van Ham, Rik J. Scheper, Erik Hooijberg, Tanja D. de Gruijl, Alfons J. M. van den Eertwegh

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine