Issue 5/2024
Content (20 Articles)
PGRN inhibits CD8+T cell recruitment and promotes breast cancer progression by up-regulating ICAM-1 on TAM
Ting Zhou, Husun Qian, Dian Zhang, Wenli Fang, MengLi Yao, He Shi, Tingmei Chen, Chengsen Chai, Bianqin Guo
Targeting osteosarcoma with canine B7-H3 CAR T cells and impact of CXCR2 Co-expression on functional activity
Jennifer W. Cao, Jessica Lake, Renata Impastato, Lyndah Chow, Luisanny Perez, Laura Chubb, Jade Kurihara, Michael R. Verneris, Steven Dow
Lipid droplets-related Perilipin-3: potential immune checkpoint and oncogene in oral squamous cell carcinoma
Yijia He, Lingyun Liu, Yuexin Dong, Xiaoxin Zhang, Yuxian Song, Yue Jing, Yanhong Ni, Yi Wang, Zhiyong Wang, Liang Ding
Efficacy of immune checkpoint inhibitors differs in various status of carcinoma: a study based on 29 cohorts with 3255 participants
Chunlan Wu, Yujun Ke, Luying Wan, Xianhe Xie
Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth
Andrew N. Wilkinson, Rui Chen, Elaina Coleborn, Trent Neilson, Khang Le, Chintan Bhavsar, Yue Wang, Sharat Atluri, Gowri Irgam, Kiefer Wong, Da Yang, Raymond Steptoe, Sherry Y. Wu
Characterization of a novel anti-PVRIG antibody with Fc-competent function that exerts strong antitumor effects via NK activation in preclinical models
Hongyu Xue, Zhimin Zhang, Li Li, Chenjuan Zhu, Keke Fei, Huijun Sha, Zhihai Wu, Xiaomin Lin, Feifei Wang, Shuaixiang Zhou, Xiya Deng, Yiming Li, Bingliang Chen, Yao Xiong, Kai Chen
DR30318, a novel tri-specific T cell engager for Claudin 18.2 positive cancers immunotherapy
Zhe Ma, Zhenxing Zhou, Wenwen Duan, Gaofeng Yao, Shimei Sheng, Sidou Zong, Xin Zhang, Changkui Li, Yuanyuan Liu, Fengting Ou, Maha Raja Dahar, Yanshan Huang, Lushan Yu
23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling
Zeping Fan, Yaru Cui, Lanying Chen, Peng Liu, Wenbin Duan
IL-2 promotes expansion and intratumoral accumulation of tumor infiltrating dendritic cells in pancreatic cancer
Tingting Gong, Xinyang Huang, Zhuoxin Wang, Ye Chu, Lifu Wang, Qi Wang
TGF-β1 and TGF-βR1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation
Zihao Niu, Peng Sun, Mark E. Zafereo, Hongliang Liu, Peng Wei, Jia Wu, Neil D. Gross, Sanjay Shete, Qingyi Wei, Guibin Zheng, Andy G. Sikora, George A. Calin, Guojun Li
SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue
Kelly J. Gregory, Holly Mason, Jesse Casaubon, Sallie S. Schneider
The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy
Wenxin Lu, Guangyu Wu, Xianyuan Miao, Jingyu Ma, Yanling Wang, Haiyan Xu, Daiyuan Shentu, Shengbai Xue, Qing Xia, Yu Wang, Liwei Wang
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression
Jingbo Ma, Jian Tan, Weiqiang Zhang, Miaochun Bai, Keqiang Liu
Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours
Manish R. Patel, Melissa Johnson, Ira Winer, Hendrik-Tobias Arkenau, Natalie Cook, Vanessa Samouëlian, Raid Aljumaily, Shigehisa Kitano, Christine Duffy, Miaomiao Ge, Mabrouk Elgadi, Lillian L. Siu
IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models
Justin Yu, Jacob Gadwa, Richard B. Ross, Michael Knitz, Laurel B. Darragh, Khalid N. M. Abdelazeem, Jessica Beynor, Brooke Neupert, Alexander Nguyen, Diemmy Nguyen, Nicholas Olimpo, Sophia Corbo, Benjamin Van Court, Angelo D’Alessandro, Anthony Saviola, Sana D. Karam
circFTO from M2 macrophage-derived small extracellular vesicles (sEV) enhances NSCLC malignancy by regulation miR-148a-3pPDK4 axis
Qingtao Liu, Pei Xu, Mingming Jin, Lei Wang, Fengqing Hu, Qi Yang, Rui Bi, Haibo Xiao, Lianyong Jiang, Fangbao Ding
Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy
Jhen-Yu Chen, Po-Yu Lin, Wei-Ze Hong, Pei-Chen Yang, Shu-Fen Chiang, Hsin-Yu Chang, Tao-Wei Ke, Ji-An Liang, William Tzu-Liang Chen, K. S. Clifford Chao, Kevin Chih-Yang Huang
The prognostic and potentially immunomodulatory role of cartilage oligomeric matrix protein in patients with gastric and esophageal adenocarcinoma
Konstantinos S. Papadakos, Gilar Gorji-Bahri, Chrysostomi Gialeli, Charlotta Hedner, Catharina Hagerling, Maria C. Svensson, Martin Jeremiasen, David Borg, Richard Fristedt, Karin Jirström, Anna M. Blom
Bifidobacterium modulation of tumor immunotherapy and its mechanism
Bo Pei, Shixuan Peng, Chuying Huang, Fuxiang Zhou
Dual-loss of PBRM1 and RAD51 identifies hyper-sensitive subset patients to immunotherapy in clear cell renal cell carcinoma
Ziyang Xu, Wenbin Jiang, Li Liu, Youqi Qiu, Jiahao Wang, Siyuan Dai, Jianming Guo, Jiejie Xu