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Annals of Hematology

Issue 7/2021

Content (32 Articles)

Open Access Primary Myelofibrosis Review Article

Thrombocytosis in children and adolescents—classification, diagnostic approach, and clinical management

Clemens Stockklausner, C. M. Duffert, H. Cario, R. Knöfler, W. Streif, A. E. Kulozik

Clinical characteristics and therapeutic outcomes of paroxysmal nocturnal hemoglobinuria patients in Turkey: a multicenter experience

Deniz Goren Sahin, Olga Meltem Akay, Muzaffer Keklik, Vahap Okan, Abdullah Karakus, Cengiz Demir, Mehmet Ali Erkurt, Kadir Ilkkilic, Rahsan Yildirim, Gulsum Akgun Cagliyan, Salih Aksu, Mehmet Hilmi Dogu, Mehmet Sinan Dal, Volkan Karakus, Ali Ihsan Gemici, Hatice Terzi, Engin Kelkitli, Serdar Sivgin, Ali Unal, Mehmet Yilmaz, Orhan Ayyildiz, Serdal Korkmaz, Bulent Eser, Fevzi Altuntas

Open Access Addiction Original Article

The rare hemoglobin variant Hb Mizuho: report of a Swiss family and literature review

Linet Njue, Cesare Medri, Peter Keller, Miriam Diepold, Behrouz Mansouri Taleghani, Alicia Rovó

Open Access Porphyrias Original Article

Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?

Petro E. Petrides, Michael Klein, Elfriede Schuhmann, Heike Torkler, Brigitte Molitor, Christian Loehr, Zahra Obermeier, Maria K. Beykirch

Acute Myeloid Leukemia Original Article

Aberrant myelomonocytic CD56 expression in Down syndrome is frequent and not associated with leukemogenesis

Manisha Gadgeel, Batool AlQanber, Steven Buck, Jeffrey W. Taub, Yaddanapudi Ravindranath, Süreyya Savaşan

Comparative study of IgG binding to megakaryocytes in immune and myelodysplastic thrombocytopenic patients

Doaa I. Elzaeem, Esmat A. El Sharkawi, Eman M. Zaki, Ayman G. Ghobrial, Aliaa S. Abd El-Fatah, Waleed M. Abd El-Hamed

Monitoring treatment with 5-Azacitidine by flow cytometry predicts duration of hematological response in patients with myelodysplastic syndrome

Dolores Subirá, Canan Alhan, Uta Oelschlaegel, Anna Porwit, Katherina Psarra, Theresia M. Westers, Nuria Golbano, Lars Nilsson, Arjan A van de Loosdrecht, Dunia de Miguel

Open Access Acute Lymphoblastic Leukemia Original Article

Clinical outcomes in patients with Philadelphia chromosome-positive leukemia treated with ponatinib in routine clinical practice—data from a Belgian registry

Timothy Devos, Violaine Havelange, Koen Theunissen, Stef Meers, Fleur Samantha Benghiat, Alain Gadisseur, Gaëtan Vanstraelen, Hélène Vellemans, Benjamin Bailly, Nikki Granacher, Philippe Lewalle, Ann De Becker, Koen Van Eygen, Mia Janssen, Agnes Triffet, Inge Vrelust, Dries Deeren, Dominiek Mazure, Julie Bekaert, Michael Beck, Dominik Selleslag

Rituximab Original Article

Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL: analysis from the iLLUMINATE study

Richard Greil, Alessandra Tedeschi, Carol Moreno, Bertrand Anz, Loree Larratt, Martin Simkovic, Devinder Gill, John G. Gribben, Ian W. Flinn, Zhengyuan Wang, Leo W. K. Cheung, Aaron N. Nguyen, Cathy Zhou, Lori Styles, Fatih Demirkan

The role of ponatinib in adult BCR-ABL1 positive acute lymphoblastic leukemia after allogeneic transplantation: a real-life retrospective multicenter study

Salvatore Leotta, Uros Markovic, Maria Cristina Pirosa, Stefania Stella, Stefania Tringali, Massimo Martino, Giorgina Specchia, Paola Carluccio, Antonio M. Risitano, Francesco Grimaldi, Ernesto Vigna, Fausto Palmieri, Raffaele Palmieri, Mario Annunziata, Giovanni Pisapia, Giulia Palazzo, Giulio Antonio Milone, Angelo Curto Pelle, Luca Scalise, Mary Ann Di Giorgio, Anna Bulla, Valerio Leotta, Francesco Di Raimondo, Giuseppe Milone

Open Access Hodgkin Lymphoma Original Article

High efficacy of BGD (bendamustine, gemcitabine, and dexamethasone) in relapsed/refractory Hodgkin Lymphoma

Ryszard Swoboda, Sebastian Giebel, Wanda Knopińska-Posłuszny, Ewa Chmielowska, Joanna Drozd-Sokołowska, Ewa Paszkiewicz-Kozik, Waldemar Kulikowski, Michał Taszner, Włodzimierz Mendrek, Jacek Najda, Tomasz Czerw, Magdalena Olszewska-Szopa, Anna Czyż, Agnieszka Giza, Wojciech Spychałowicz, Edyta Subocz, Paweł Szwedyk, Aleksandra Krzywon, Agata Wilk, Jan Maciej Zaucha

Multiple Myeloma Original Article

Treatment patterns and outcomes in real-world transplant-ineligible patients newly diagnosed with multiple myeloma

María José Cejalvo, Gabriela Bustamante, Esther González, Judith Vázquez-Álvarez, Ricarda García, Ángel Ramírez-Payer, Ernesto Pérez-Persona, Eugenia Abella, Sebastián Garzón, Antoni García, Isidro Jarque, Marta Sonia González, Antonia Sampol, Cristina Motlló, Josep María Martí, Magdalena Alcalá, Rafael Duro, Yolanda González, José Luis Sastre, Josep Sarrà, Giselle Lostaunau, Rocío López, Javier de la Rubia

Multiple Myeloma Original Article

Characteristics and survival trends in Finnish multiple myeloma patients—a nationwide real-world evidence study

Iiro Toppila, Tatu Miettinen, Mariann I. Lassenius, Juha Lievonen, Melissa Bauer, Pekka Anttila

Multiple Myeloma Original Article

Pleural effusion-based nomogram to predict outcomes in unselected patients with multiple myeloma: a large single center experience

Zi-Liang Hou, Yu Kang, Guang-Zhong Yang, Zhen Wang, Feng Wang, Yan-Xia Yu, Wen-Ming Chen, Huan-Zhong Shi

Multiple Myeloma Original Article

Oral therapy adherence and satisfaction in patients with multiple myeloma

Marine Solano, Etienne Daguindau, Cyril Faure, Pierre Loriod, Coline Pain, Anne-Cécile Maes, Pauline Marguet, Marie Kroemer, Anne Rumpler, Jean Fontan, Eric Deconinck, Samuel Limat, Anne-Laure Clairet

Multiple Myeloma Original Article

A novel Twist1/hsa-miR138-5p/caspase-3 pathway regulates cell proliferation and apoptosis of human multiple myeloma

Wenjiao Qin, Qin Liu, Xiaoping Xu, Aiping Liu, Huating Zhang, Jingwen Gu, Tao Zhang

Multiple Myeloma Original Article

Survival and treatment patterns of patients with relapsed or refractory multiple myeloma in France — a cohort study using the French National Healthcare database (SNDS)

Cyrille Touzeau, Nadia Quignot, Jie Meng, Heng Jiang, Artak Khachatryan, Moushmi Singh, Vanessa Taieb, Jean-Vannak Chauny, Gaëlle Désaméricq

Open Access Graft-Versus-Host Disease Original Article

Impact of anti-thymocyte globulin dose for graft-versus-host disease prophylaxis in allogeneic hematopoietic cell transplantation from matched unrelated donors: a multicenter experience

Sara Butera, Marco Cerrano, Lucia Brunello, Chiara Maria Dellacasa, Danilo Giuseppe Faraci, Sara Vassallo, Nicola Mordini, Roberto Sorasio, Francesco Zallio, Alessandro Busca, Benedetto Bruno, Luisa Giaccone

Single cord blood transplantation for acute myeloid leukemia patients aged 60 years or older: a retrospective study in Japan

Masamichi Isobe, Takaaki Konuma, Masayoshi Masuko, Naoyuki Uchida, Shigesaburo Miyakoshi, Yasuhiro Sugio, Shuro Yoshida, Masatsugu Tanaka, Yoshiko Matsuhashi, Norimichi Hattori, Makoto Onizuka, Nobuyuki Aotsuka, Yasushi Kouzai, Atsushi Wake, Takafumi Kimura, Tatsuo Ichinohe, Yoshiko Atsuta, Masamitsu Yanada

Lymphoma Original Article

Gastrointestinal toxicity of high-dose melphalan in autologous hematopoietic stem cell transplantation: identification of risk factors and a benchmark for experimental therapies

Christian A. Gordillo, Sapna Parmar, Miranda Blanco, Elsa M. Delille, Amer Assal, Markus Mapara, Ran Reshef

Acute Myeloid Leukemia Original Article

Magnesium levels and outcome after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia

Linus Angenendt, Isabel Hilgefort, Jan-Henrik Mikesch, Bernhard Schlüter, Wolfgang E. Berdel, Georg Lenz, Matthias Stelljes, Christoph Schliemann

Epstein-Barr Virus Original Article

The time-dependent effects of early-onset Epstein-Barr viremia on adult acute leukemia patients following allo-HSCT with ATG-containing MAC regimen

Peng Ke, Xinyou Zhang, Songbai Liu, Qian Zhu, Xiao Ma, Feng Chen, Xiaowen Tang, Yue Han, ZhengZheng Fu, Suning Chen, Depei Wu, Huiying Qiu, Jihao Zhou, Xiebing Bao

Lymphoma Letter to the Editor

Complete regression of an HCV-associated diffuse large B cell lymphoma achieved by chemoimmuno-free antiviral therapy

Xiao-Hong Sun, Li-Na Wang, Hai-Zhen Ma, Zi-Jian Li, Ya-Ming Xi

Open Access Acute Myeloid Leukemia Letter to the Editor

HHV-6 encephalitis in a non-transplanted adult acute myeloid leukemia patient

Margarete Voigt, Konrad Sinn, Amer Malouhi, Thomas Gecks, Jan Zinke, Inken Hilgendorf, Sebastian Scholl, Andreas Hochhaus, Ulf Schnetzke

Hemolytic Anemia Letter to the Editor

A belated diagnosis of G6PD deficiency in an 81-year-old woman

Violaine Tran Quang, Sihem Tarfi, Valentine Loustau, Stéphane Moutereau, Marc Michel, Orianne Wagner-Ballon

Thalassemia Letter to the Editor

Variations in hemoglobin level and morbidity burden in non-transfusion-dependent β-thalassemia

Khaled M. Musallam, Maria Domenica Cappellini, Ali T. Taher

Ribavirin Letter to the Editor

Hepatocellular carcinoma in patients with thalassemia in the post-DAA era: not a disappearing entity

Paolo Ricchi, Silvia Costantini, Anna Spasiano, Patrizia Cinque, Simona Esposito, Aldo Filosa

Open Access Acute Myeloid Leukemia Correction

Correction to: Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial

Michael Heuser, B. Douglas Smith, Walter Fiedler, Mikkael A. Sekeres, Pau Montesinos, Brian Leber, Akil Merchant, Cristina Papayannidis, José A. Pérez-Simón, Caroline J. Hoang, Thomas O’Brien, Weidong Wendy Ma, Mirjana Zeremski, Ashleigh O’Connell, Geoffrey Chan, Jorge E. Cortes

Open Access Hodgkin Lymphoma Correction

Correction to: High efficacy of BGD (bendamustine, gemcitabine, and dexamethasone) in relapsed/refractory Hodgkin lymphoma

Ryszard Swoboda, Sebastian Giebel, Wanda Knopińska-Posłuszny, Ewa Chmielowska, Joanna Drozd-Sokołowska, Ewa Paszkiewicz-Kozik, Waldemar Kulikowski, Michał Taszner, Włodzimierz Mendrek, Jacek Najda, Tomasz Czerw, Magdalena Olszewska-Szopa, Anna Czyż, Agnieszka Giza, Wojciech Spychałowicz, Edyta Subocz, Paweł Szwedyk, Aleksandra Krzywon, Agata Wilk, Jan Maciej Zaucha

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.