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Advances in Therapy

Issue 10/2023

Content (37 Articles)

Avelumab as First-Line Maintenance Treatment in Locally Advanced or Metastatic Urothelial Carcinoma

André Mansinho, Andreia Cruz, Lorenzo Marconi, Cidália Pinto, Isabel Augusto

Open Access Influenza Review

Understanding the Global Burden of Influenza in Adults Aged 18–64 years: A Systematic Literature Review from 2012 to 2022

Farzaneh Maleki, Verna Welch, Santiago M. C. Lopez, Alejandro Cane, Jakob Langer, Ashley Enstone, Kristen Markus, Olivia Wright, Nicole Hewitt, Isabelle Whittle

Open Access SCLC Review

Real-World Outcomes of Trilaciclib Among Patients with Extensive-Stage Small Cell Lung Cancer Receiving Chemotherapy

Jerome Goldschmidt, Lowell Hart, Jeffrey Scott, Kristen Boykin, Ray Bailey, Trevor Heritage, Lorena Lopez-Gonzalez, Zheng-Yi Zhou, Marie Louise Edwards, Alisha Monnette, Augustina Ogbonnaya, Kathryn Deyoung, Divea Venkatasetty, Ping Shi, Lindsay Aton, Huan Huang, Paul R. Conkling, Lucio Gordan

Implementing an Evidence-Based COPD Hospital Discharge Protocol: A Narrative Review and Expert Recommendations

Marc Miravitlles, Mohit Bhutani, John R. Hurst, Frits M. E. Franssen, Job F. M. van Boven, Ee Ming Khoo, Jing Zhang, Stephen Brunton, Daiana Stolz, Tonya Winders, Kazuhisa Asai, Jane E. Scullion

Open Access Chronic Obstructive Lung Disease Original Research

DElaying Disease Progression In COPD with Early Initiation of Dual Bronchodilator or Triple Inhaled PharmacoTherapy (DEPICT): A Predictive Modelling Approach

Dave Singh, Diego Litewka, Rafael Páramo, Adrian Rendon, Abdullah Sayiner, Suzana E. Tanni, Sudeep Acharya, Bhumika Aggarwal, Afisi S. Ismaila, Raj Sharma, Peter Daley-Yates

Itraconazole Original Research

Physiologically Based Pharmacokinetic Modeling to Simulate CYP3A4-Mediated Drug-Drug Interactions for Pyrotinib

Liang Ni, Liang Zheng, Yueyue Liu, Wenwen Xu, Yingjie Zhao, Ling Wang, Qian Zhang, Wei Hu, Xijing Chen

Open Access Ulcerative Colitis Original Research

Unmet Needs in Real-World Advanced Therapy-Naïve and -Experienced Patients with Moderately to Severely Active Ulcerative Colitis in the United States

Anita Afzali, Rina Lukanova, Fritha Hennessy, Sumie Kakehi, Hannah Knight, Gary Milligan, Komal Gupte-Singh

Open Access Breast Cancer Original Research

An EMT-Related Gene Signature to Predict the Prognosis of Triple-Negative Breast Cancer

Bo Zhang, Rong Zhao, Qi Wang, Ya-Jing Zhang, Liu Yang, Zhou-Jun Yuan, Jun Yang, Qian-Jun Wang, Liang Yao

Open Access Chronic Kidney Disease Original Research

Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme

Vivekanand Jha, Saeed M. G. Al-Ghamdi, Guisen Li, Mai-Szu Wu, Panagiotis Stafylas, Lise Retat, Joshua Card-Gowers, Salvatore Barone, Claudia Cabrera, Juan Jose Garcia Sanchez

Ustekinumab Original Research

Real-World Persistence of Ustekinumab in the Treatment of Inflammatory Bowel Disease

Brian Bressler, Jennifer Jones, Tracy S. H. In, Tommy Lan, Cristian Iconaru, John K. Marshall

Open Access Ulcerative Colitis Original Research

Modeling of Treatment Outcomes with Tofacitinib Maintenance Therapy in Patients with Ulcerative Colitis: A Post Hoc Analysis of Data from the OCTAVE Clinical Program

Michael Chiorean, Marco Daperno, Charlie W. Lees, Gianluca Bonfanti, Dimitrios Soudis, Irene Modesto, J. Jasper Deuring, Roger A. Edwards

Open Access Mood Disorders Original Research

The Economic Burden of Adults with Major Depressive Disorder in the United States (2019)

Paul Greenberg, Abhishek Chitnis, Derek Louie, Ellison Suthoff, Shih-Yin Chen, Jessica Maitland, Patrick Gagnon-Sanschagrin, Andree-Anne Fournier, Ronald C. Kessler

Open Access Prostate Cancer Original Research

Healthcare Costs in Men with Metastatic Castration-Resistant Prostate Cancer: An Analysis of US Medicare Fee-For-Service Claims

Stephen J. Freedland, Matthew R. Davis, Andrew J. Epstein, Bhakti Arondekar, Jasmina I. Ivanova

Open Access Direct Oral Anticoagulant Original Research

Unintended Consequences of Increased Out-of-Pocket Costs During Medicare Coverage Gap on Anticoagulant Discontinuation and Stroke

Tabassum Salam, Urvi Desai, Patrick Lefebvre, E Jian-Yu, Alexandra Greatsinger, Nina Zacharia, François Laliberté, Brahim Bookhart, Akshay Kharat

Open Access Osimertinib Original Research

Real-World Data About Treatment Outcomes for Patients with EGFR-Mutated NSCLC Resistance to Osimertinib and Platinum-Based Chemotherapy

Hidetoshi Hayashi, Makoto Nishio, Michiko Takahashi, Hiroaki Tsuchiya, Mami Kasahara-Kiritani

Open Access Triptorelin Original Research

Efficacy and Safety of Triptorelin 3-Month Formulation in Chinese Children with Central Precocious Puberty: A Phase 3, Open-Label, Single-Arm Study

Xiaoping Luo, Cai Zhang, Yu Yang, Xu Xu, Xinran Cheng, Haiyan Wei, Lanying Wang, Frank Huang, Xiaofeng Shi, Patrick Cabri

Open Access Spinal Muscular Atrophy Original Research

Health Care Resource Utilization and Costs for Patients with Spinal Muscular Atrophy: Findings from a Retrospective US Claims Database Analysis

Walter Toro, Min Yang, Mihaela Georgieva, Wei Song, Anish Patel, Anya (Xinyi) Jiang, Angela Zhao, Nicole LaMarca, Omar Dabbous

Open Access Multiple Myeloma Original Research

Post-infusion Costs Associated with Idecabtagene Vicleucel Treatment for Patients with Relapsed/Refractory Multiple Myeloma in the KarMMa Trial

November McGarvey, Brian Ung, Thomas Carattini, Ken Imanak, Abraham Lee, Timothy B. Campbell, Pallavi Patwardhan

Open Access Glaucoma Original Research

Phase 3 Clinical Trial Comparing the Safety and Efficacy of Netarsudil to Ripasudil in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: Japan Rho Kinase Elevated Intraocular Pressure Treatment Trial (J-ROCKET)

Makoto Araie, Kazuhisa Sugiyama, Kenji Aso, Koji Kanemoto, Ryo Iwata, David A. Hollander, Michelle Senchyna, Casey C. Kopczynski

Acromegaly Brief Report

Key Device Attributes for Injectable Somatostatin Receptor Ligand Therapy in Acromegaly and Neuroendocrine Tumours

Jens Otto L. Jørgensen, Wouter W. de Herder, Wendy A. Martin, Teodora Kolarova, Muriël Marks, Cecilia Follin, Wanda Geilvoet, Shlomo Melmed

Open Access Chronic Obstructive Lung Disease Correction

Correction to: DElaying Disease Progression In COPD with Early Initiation of Dual Bronchodilator or Triple Inhaled PharmacoTherapy (DEPICT): A Predictive Modelling Approach

Dave Singh, Diego Litewka, Rafael Páramo, Adrian Rendon, Abdullah Sayiner, Suzana E. Tanni, Sudeep Acharya, Bhumika Aggarwal, Afisi S. Ismaila, Raj Sharma, Peter Daley-Yates

Open Access Laryngectomy Correction

Correction to: Pharyngeal Reconstruction Methods to Reduce the Risk of Pharyngocutaneous Fistula After Primary Total Laryngectomy: A Scoping Review

Alvaro Sanabria, María Paula Olivera, Carlos Chiesa-Estomba, Marc Hamoir, Luiz P. Kowalski, Fernando López, Antti Mäkitie, K. Thomas Robbins, Juan Pablo Rodrigo, Cesare Piazza, Ashok Shaha, Elizabeth Sjögren, Carlos Suarez, Mark Zafereo, Alfio Ferlito

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine