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01-11-2020 | Acute Liver Failure | DDS–SIRC COOPERATIVE CONFERENCES
Casting a Wider NET: An Unusual Cause of Acute Liver Failure in a Pregnant Patient
Published in: Digestive Diseases and Sciences | Issue 11/2020
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We present a case patient in her second trimester of pregnancy who developed acute liver failure from metastatic neuroendocrine tumor (NET). Although she underwent prompt induction of a non-viable fetus due to initial concerns of hemolysis, elevated liver enzymes, and low platelet count syndrome, her liver function continued to deteriorate postpartum. She was subsequently transferred to our institution in order to undergo further evaluation that included a transjugular liver biopsy and subsequent diagnosis of high-grade NET. She was given salvage carboplatin-based chemotherapy, as she was not a liver transplant candidate. Unfortunately, the patient expired from cardiovascular collapse as a component of multiorgan failure.