Issue 5/2019
The basis of selective cellular and regional vulnerability in neurodegeneration (Pages: 677 - 770)
Content (14 Articles)
On the journey to uncover the causes of selective cellular and regional vulnerability in neurodegeneration
Zane Jaunmuktane, Sebastian Brandner
Selective vulnerability in α-synucleinopathies
Javier Alegre-Abarrategui, Katherine R. Brimblecombe, Rosalind F. Roberts, Elisavet Velentza-Almpani, Bension S. Tilley, Nora Bengoa-Vergniory, Christos Proukakis
Cellular and regional vulnerability in frontotemporal tauopathies
Shelley L. Forrest, Jillian J. Kril, Glenda M. Halliday
The basis of cellular and regional vulnerability in Alzheimer’s disease
Dunja Mrdjen, Edward J. Fox, Syed A. Bukhari, Kathleen S. Montine, Sean C. Bendall, Thomas J. Montine
The basis of clinicopathological heterogeneity in TDP-43 proteinopathy
Ito Kawakami, Tetsuaki Arai, Masato Hasegawa
Lewy-related pathology exhibits two anatomically and genetically distinct progression patterns: a population-based study of Finns aged 85+
Anna Raunio, Karri Kaivola, Jarno Tuimala, Mia Kero, Minna Oinas, Tuomo Polvikoski, Anders Paetau, Pentti J. Tienari, Liisa Myllykangas
Increased prevalence of granulovacuolar degeneration in C9orf72 mutation
Yuichi Riku, Charles Duyckaerts, Susana Boluda, Isabelle Plu, Isabelle Le Ber, Stéphanie Millecamps, François Salachas, Franck Letournel, Marie-Laure Martin-Négrier, Françoise Chapon, Catherine Godfraind, Claude-Alain Maurage, Vincent Deramecourt, David Meyronet, Nathalie Streichenberger, André Maues de Paula, Valérie Rigau, Fanny Vandenbos-Burel, Serge Milin, Dan Christian Chiforeanu, Annie Laquerrière, Béatrice Lannes, Mathilde Duchesne, Mari Yoshida, Takashi Ando, Masahisa Katsuno, Gen Sobue, Danielle Seilhean
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy
Christopher P. Cali, Maribel Patino, Yee Kit Tai, Wan Yun Ho, Catriona A. McLean, Christopher M. Morris, William W. Seeley, Bruce L. Miller, Carles Gaig, Jean Paul G. Vonsattel, Charles L. White III, Sigrun Roeber, Hans Kretzschmar, Juan C. Troncoso, Claire Troakes, Marla Gearing, Bernardino Ghetti, Vivianna M. Van Deerlin, Virginia M.-Y. Lee, John Q. Trojanowski, Kin Y. Mok, Helen Ling, Dennis W. Dickson, Gerard D. Schellenberg, Shuo-Chien Ling, Edward B. Lee
Splicing repression is a major function of TDP-43 in motor neurons
Aneesh Donde, Mingkuan Sun, Jonathan P. Ling, Kerstin E. Braunstein, Bo Pang, Xinrui Wen, Xueying Cheng, Liam Chen, Philip C. Wong
Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions
Damian Stichel, Daniel Schrimpf, Belén Casalini, Jochen Meyer, Annika K. Wefers, Philipp Sievers, Andrey Korshunov, Christian Koelsche, David E. Reuss, Annekathrin Reinhardt, Azadeh Ebrahimi, Francisco Fernández-Klett, Tobias Kessler, Dominik Sturm, Jonas Ecker, Till Milde, Christel Herold-Mende, Olaf Witt, Stefan M. Pfister, Wolfgang Wick, David T. W. Jones, Andreas von Deimling, Felix Sahm
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia
Clévio Nóbrega, Liliana Mendonça, Adriana Marcelo, Antonin Lamazière, Sandra Tomé, Gaetan Despres, Carlos A. Matos, Fatich Mechmet, Dominique Langui, Wilfred den Dunnen, Luis Pereira de Almeida, Nathalie Cartier, Sandro Alves
Contextualizing the pathology in the essential tremor cerebellar cortex: a patholog-omics approach
Elan D. Louis, Chloë A. Kerridge, Debotri Chatterjee, Regina T. Martuscello, Daniel Trujillo Diaz, Arnulf H. Koeppen, Sheng-Han Kuo, Jean-Paul G. Vonsattel, Peter A. Sims, Phyllis L. Faust
Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas
Emily A. Sloan, Tabitha Cooney, Nancy Ann Oberheim Bush, Robin Buerki, Jennie Taylor, Jennifer L. Clarke, Joseph Torkildson, Cassie Kline, Alyssa Reddy, Sabine Mueller, Anu Banerjee, Nicholas Butowski, Susan Chang, Praveen V. Mummaneni, Dean Chou, Lee Tan, Philip Theodosopoulos, Michael McDermott, Mitchel Berger, Corey Raffel, Nalin Gupta, Peter P. Sun, Yi Li, Vinil Shah, Soonmee Cha, Steve Braunstein, David R. Raleigh, David Samuel, David Scharnhorst, Cynthia Fata, Hua Guo, Gregory Moes, John Y. H. Kim, Carl Koschmann, Jessica Van Ziffle, Courtney Onodera, Patrick Devine, James P. Grenert, Julieann C. Lee, Melike Pekmezci, Joanna J. Phillips, Tarik Tihan, Andrew W. Bollen, Arie Perry, David A. Solomon
Correction to: ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD
Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, Rita Sattler