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Acta Neuropathologica

Issue 4/2023

Content (10 Articles)

Open Access Astrocytoma Original Paper

Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma

Daniel Picard, Jörg Felsberg, Maike Langini, Paweł Stachura, Nan Qin, Jadranka Macas, Yvonne Reiss, Jasmin Bartl, Florian Selt, Romain Sigaud, Frauke-D. Meyer, Anja Stefanski, Kai Stühler, Lucia Roque, Rafael Roque, Aleksandra A. Pandyra, Triantafyllia Brozou, Christiane Knobbe-Thomsen, Karl H. Plate, Alexander Roesch, Till Milde, Guido Reifenberger, Gabriel Leprivier, Claudia C. Faria, Marc Remke

Open Access Alzheimer's Disease Original Paper

Inflammation and the pathological progression of Alzheimer’s disease are associated with low circulating choline levels

Jessica M. Judd, Paniz Jasbi, Wendy Winslow, Geidy E. Serrano, Thomas G. Beach, Judith Klein-Seetharaman, Ramon Velazquez

Open Access Central Nervous System Trauma Original Paper

Neuronal tau pathology worsens late-phase white matter degeneration after traumatic brain injury in transgenic mice

Fengshan Yu, Diego Iacono, Daniel P. Perl, Chen Lai, Jessica Gill, Tuan Q. Le, Patricia Lee, Gauthaman Sukumar, Regina C. Armstrong

TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models

Shintaro Tsuboguchi, Yuka Nakamura, Tomohiko Ishihara, Taisuke Kato, Tokiharu Sato, Akihide Koyama, Hideki Mori, Yuka Koike, Osamu Onodera, Masaki Ueno

Open Access Pathology Original Paper

Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease

Evelyn Berger-Sieczkowski, Verena Endmayr, Carmen Haider, Gerda Ricken, Philipp Jauk, Stefan Macher, Walter Pirker, Birgit Högl, Anna Heidbreder, Peter Schnider, Eszter Bradley-Zechmeister, Sara Mariotto, Inga Koneczny, Raphael Reinecke, Gregor Kasprian, Corinna Weber, Melanie Bergmann, Ivan Milenkovic, Thomas Berger, Carles Gaig, Lidia Sabater, Francesc Graus, Ellen Gelpi, Romana Höftberger

Open Access Glioblastoma Correspondence

Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival

Hans-Georg Wirsching, Jörg Felsberg, Michael Prummer, Vlad Moisoiu, Roxanne Lourman, Caroline Hertler, Michelle Antonios, Patrick J. Cimino, Patrick Roth, Thierry Gorlia, Robert M. Prins, Timothy Cloughesy, Patrick Y. Wen, Eric C. Holland, Guido Reifenberger, Michael Weller

Parkinson's Disease Correspondence

The variance in phosphorylated, insoluble ⍺-synuclein in humans, rats, and mice is not mainly driven by biological sex

Kristin M. Miner, Anuj S. Jamenis, Tarun N. Bhatia, Rachel N. Clark, Muslim Abbas, Kelvin C. Luk, Rehana K. Leak

Decreased dystrophin expression and elevated dystrophin-targeting miRNAs in anti-HMGCR immune-mediated necrotizing myopathy

Maude B. Marmen, Zakaria Orfi, Junio Dort, Jean-Philippe Proulx-Gauthier, Nicolas Chrestian, Nicolas A. Dumont, Benjamin Ellezam

Pathology Correction

Correction to: Intraneuronal aggregation of the β‑CTF fragment of APP (C99) induces Aβ‑independent lysosomal-autophagic pathology

Inger Lauritzen, Raphaëlle Pardossi‑Piquard, Alexandre Bourgeois, Sophie Pagnotta, Maria‑Grazia Biferi, Martine Barkats, Pascale Lacor, William Klein, Charlotte Bauer, Frederic Checler

Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease

Aivi T. Nguyen, Kui Wang, Gang Hu, Xuran Wang, Zhen Miao, Joshua A. Azevedo, EunRan Suh, Vivianna M. Van Deerlin, David Choi, Kathryn Roeder, Mingyao Li, Edward B. Lee