Issue 3/2023
Content (12 Articles)
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy
Manuel Flores-Leon, Tiago Fleming Outeiro
Vagus nerve inflammation contributes to dysautonomia in COVID-19
Marcel S. Woo, Mohsin Shafiq, Antonia Fitzek, Matthias Dottermusch, Hermann Altmeppen, Behnam Mohammadi, Christina Mayer, Lukas C. Bal, Lukas Raich, Jakob Matschke, Susanne Krasemann, Susanne Pfefferle, Thomas Theo Brehm, Marc Lütgehetmann, Julia Schädler, Marylyn M. Addo, Julian Schulze zur Wiesch, Benjamin Ondruschka, Manuel A. Friese, Markus Glatzel
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy
Shelley L. Forrest, Seojin Lee, Nasna Nassir, Ivan Martinez-Valbuena, Valerie Sackmann, Jun Li, Awab Ahmed, Maria Carmela Tartaglia, Lars M. Ittner, Anthony E. Lang, Mohammed Uddin, Gabor G. Kovacs
Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old
Lorena Sordo, Tianchen Qian, Syed A. Bukhari, Katelynn M. Nguyen, Davis C. Woodworth, Elizabeth Head, Claudia H. Kawas, María M. Corrada, Thomas J. Montine, S. Ahmad Sajjadi
Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum
Lauren M. Gittings, Eric B. Alsop, Jerry Antone, Mo Singer, Timothy G. Whitsett, Rita Sattler, Kendall Van Keuren-Jensen
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS
Amr Aly, Zsofia I. Laszlo, Sandeep Rajkumar, Tugba Demir, Nicole Hindley, Douglas J. Lamont, Johannes Lehmann, Mira Seidel, Daniel Sommer, Mirita Franz-Wachtel, Francesca Barletta, Simon Heumos, Stefan Czemmel, Edor Kabashi, Albert Ludolph, Tobias M. Boeckers, Christopher M. Henstridge, Alberto Catanese
SMN regulates GEMIN5 expression and acts as a modifier of GEMIN5-mediated neurodegeneration
Tyler R. Fortuna, Sukhleen Kour, Anuradha Venkatakrishnan Chimata, Anixa Muiños-Bühl, Eric N. Anderson, Charlie H. Nelson IV, Caroline Ward, Om Chauhan, Casey O’Brien, Dhivyaa Rajasundaram, Deepa S. Rajan, Brunhilde Wirth, Amit Singh, Udai Bhan Pandey
Integrated genetic analyses of immunodeficiency-associated Epstein-Barr virus- (EBV) positive primary CNS lymphomas
Leon D. Kaulen, Evgeniya Denisova, Felix Hinz, Ling Hai, Dennis Friedel, Octavian Henegariu, Dirk C. Hoffmann, Jakob Ito, Alexandros Kourtesakis, Pascal Lehnert, Sofia Doubrovinskaia, Philipp Karschnia, Louisa von Baumgarten, Tobias Kessler, Joachim M. Baehring, Benedikt Brors, Felix Sahm, Wolfgang Wick
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4
Erik A. Williams, Priscilla K. Brastianos, Hiroaki Wakimoto, Amir Zolal, Mariella G. Filbin, Daniel P. Cahill, Sandro Santagata, Tareq A. Juratli
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics
Pascal D. Johann, Lea Altendorf, Emma-Maria Efremova, Till Holsten, Mona Steinbügl, Karolina Nemes, Alicia Eckhardt, Catena Kresbach, Michael Bockmayr, Arend Koch, Christine Haberler, Manila Antonelli, John DeSisto, Martin U. Schuhmann, Peter Hauser, Reiner Siebert, Susanne Bens, Marcel Kool, Adam L. Green, Martin Hasselblatt, Michael C. Frühwald, Ulrich Schüller
DNA-methylation subgroups carry no prognostic significance in ATRT-SHH patients in clinical trial cohorts
Quynh T. Tran, Santhosh A. Upadhyaya, Catherine A. Billups, Arzu Onar-Thomas, Md. Zahangir Alom, Steven S. Carey, Giles W. Robinson, David W. Ellison, Amar Gajjar, Brent A. Orr
Chronic traumatic encephalopathy in a female ex-professional Australian rules footballer
Catherine M. Suter, Andrew J. Affleck, Alan J. Pearce, Reimar Junckerstorff, Maggie Lee, Michael E. Buckland